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    • 8. 发明公开
    • GERMINAL SUBSTITUIERTE AMINE
    • 终端替代氨基酸
    • EP1088029A1
    • 2001-04-04
    • EP99932703.4
    • 1999-06-18
    • MERCK PATENT GmbH
    • BUCHHOLZ, HerwigWELZ-BIERMANN, Urs
    • C08L1/00
    • C07D295/023B01J31/0212B01J31/0237B01J31/0274B01J2231/40C07C209/66C07C209/68C07C2601/08C07C2601/14C07D295/03C07C211/08C07C211/16C07C211/17C07C211/21C07C211/27
    • The present invention relates to an amine of general formula (I), in which R?1 and R2¿ may be the same or different and represent each independently substituted or non-substituted alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkinyl, aryl or trialkylsilyl. R?1 and R2¿ can also form together with the nitrogen atom to which they are bound a substituted or non-substituted cycloalkyl ring which may contain, together with the nitrogen atom, at least one other heteroatom selected from the group comprising nitrogen, oxygen and sulphur. R3 is selected from the group comprising hydrogen and methyl optionally substituted with 1 to 3 fluorine atoms, while R?4 and R5¿ may be the same or different and represent each independently substituted or non-substituted alkyl, cycloalkyl, alkenyl, cycloalkenyl or alkinyl. This invention also relates to a salt thereof.
    • 本发明涉及通式(I)的胺,其中R 1和R 2可以相同或不同,表示各自独立地取代或未取代的烷基,环烷基,烯基,环烯基,炔基, 芳基或三烷基甲硅烷基。 R 1和R 2也可以与它们所连接的氮原子一起形成取代或未取代的环烷基环,其可以与氮原子一起含有至少一个选自以下的基团的其它杂原子: 氮,氧和硫。 R 3选自氢和可以被1至3个氟原子取代的甲基,而R 4和R 5可以相同或不同,并且各自独立地表示烷基,环烷基,烯基,环烯基, 炔基或取代或未取代的芳基。 R 4和R 5也可以表示被取代或未取代的芳基,环烷基,烯基,环烯基或炔基取代的烷基,条件是至少一个R 4和R 5基团 包括芳基。 本发明还涉及其盐。