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1. 发明授权

EP1140284B1 AV SYNCHRONOUS CARDIAC PACING SYSTEM DELIVERING MULTI-SITE VENTRICULAR PACING TRIGGERED BY A VENTRICULAR SENSE EVENT DURING THE AV DELAY 有权
标题翻译： AV同步起搏器系统刺激触发的甲WHILE阿维·德利几种心室感测LOCATIONS心室事件
公开(公告)号：EP1140284B1
公开(公告)日：2005-03-23
申请号：EP00974021.8
申请日：2000-10-27
申请人： Medtronic, Inc.
发明人： YERICH, Charles, G. , KLECKNER, Karen, J. , JURAN, Carleen, J.
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/3627
摘要： A pacing system for selectively sensing spontaneous ventricular cardiac depolarizations at first and second spaced apart ventricular sites during the time-out of an AV delay and delivering pace pulses to the spaced apart ventricular sites in a triggered pacing mode. The first and second ventricular sites are preferably right ventricular (RV) and left ventricular (LV) pace/sense electrode sites, and RV event and LV event signals are sensed at the RV and LV pace/sense electrodes A V-A pacing escape interval and a ventricular refractory period, a trigger pace window, an upper rate interval and further post-event time periods are started upon a RV or LV sense event or a first ventricular pace pulse delivered upon time-out of the AV delay. A triggered ventricular pace pulse or pulses is delivered to one or both of the RV and LV pace/sense electrode sites upon detecting an RV sense event or LV sense event during the AV delay. In one triggered pacing mode, a RV or LV pace pulse is delivered upon a RV or LV sense event during the AV delay to one of the RV or LV pace/sense electrode sites. In another triggered pacing mode, a triggered pace pulse is delivered to the other one of the RV or LV pace/sense electrode sites after a triggered pacing delay timed from a non-refractory RV or LV sense event occurring during the AV delay. In still another triggered pacing mode, a first pace pulse is delivered upon a RV or LV sense event, the triggered pacing delay is timed out, and a second pace pulse is delivered to the other one of the RV or LV pace/sense electrode sites after time-out of the triggered pacing delay. Triggered ventricular pacing is disabled during the V-A escape interval. Such a system could be employed in pacemakers that are part of a cardio defibrillator system if desired.

2. 发明公开

EP1140284A1 AV SYNCHRONOUS CARDIAC PACING SYSTEM DELIVERING MULTI-SITE VENTRICULAR PACING TRIGGERED BY A VENTRICULAR SENSE EVENT DURING THE AV DELAY 有权
标题翻译： AV同步起搏器系统刺激触发的甲WHILE阿维·德利几种心室感测LOCATIONS心室事件
公开(公告)号：EP1140284A1
公开(公告)日：2001-10-10
申请号：EP00974021.8
申请日：2000-10-27
申请人： MEDTRONIC, INC.
发明人： YERICH, Charles, G. , KLECKNER, Karen, J. , JURAN, Carleen, J.
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/3627
摘要： A pacing system for selectively sensing spontaneous ventricular cardiac depolarizations at first and second spaced apart ventricular sites during the time-out of an AV delay and delivering pace pulses to the spaced apart ventricular sites in a triggered pacing mode. The first and second ventricular sites are preferably right ventricular (RV) and left ventricular (LV) pace/sense electrode sites, and RV event and LV event signals are sensed at the RV and LV pace/sense electrodes A V-A pacing escape interval and a ventricular refractory period, a trigger pace window, an upper rate interval and further post-event time periods are started upon a RV or LV sense event or a first ventricular pace pulse delivered upon time-out of the AV delay. A triggered ventricular pace pulse or pulses is delivered to one or both of the RV and LV pace/sense electrode sites upon detecting an RV sense event or LV sense event during the AV delay. In one triggered pacing mode, a RV or LV pace pulse is delivered upon a RV or LV sense event during the AV delay to one of the RV or LV pace/sense electrode sites. In another triggered pacing mode, a triggered pace pulse is delivered to the other one of the RV or LV pace/sense electrode sites after a triggered pacing delay timed from a non-refractory RV or LV sense event occurring during the AV delay. In still another triggered pacing mode, a first pace pulse is delivered upon a RV or LV sense event, the triggered pacing delay is timed out, and a second pace pulse is delivered to the other one of the RV or LV pace/sense electrode sites after time-out of the triggered pacing delay. Triggered ventricular pacing is disabled during the V-A escape interval. Such a system could be employed in pacemakers that are part of a cardio defibrillator system if desired.

3. 发明授权

EP1885446B1 SYSTEM FOR REMOTE PACING THRESHOLD ASSESSMENT 有权
标题翻译：系统起搏阈值的远程评估
公开(公告)号：EP1885446B1
公开(公告)日：2012-12-05
申请号：EP06739405.6
申请日：2006-03-23
申请人： Medtronic, Inc.
发明人： YERICH, Charles, G. , KLECKNER, Karen, J.
IPC分类号： A61N1/37
CPC分类号： G06F19/3418 , A61N1/371 , A61N1/37282 , G06F19/00
摘要： A cardiac rhythm management system includes an implantable medical device capable of delivering cardiac therapy and sensing an EGM. The implantable medical device undergoes threshold testing and transmits testing data to a computer via a remote monitor.

4. 发明公开

EP1885446A1 SYSTEM AND METHOD FOR REMOTE PACING THRESHOLD ASSESSMENT 有权
标题翻译：系统起搏阈值的远程评估
公开(公告)号：EP1885446A1
公开(公告)日：2008-02-13
申请号：EP06739405.6
申请日：2006-03-23
申请人： MEDTRONIC, INC.
发明人： YERICH, Charles, G. , KLECKNER, Karen, J.
IPC分类号： A61N1/37
CPC分类号： G06F19/3418 , A61N1/371 , A61N1/37282 , G06F19/00
摘要： A cardiac rhythm management system includes an implantable medical device capable of delivering cardiac therapy and sensing an EGM. The implantable medical device undergoes threshold testing and transmits testing data to a computer via a remote monitor.

5. 发明公开

EP0794812A2 METHOD AND APPARATUS FOR RATE-RESPONSIVE CARDIAC PACING 失效
标题翻译：方法和装置时钟敏感HERSTIMULATOREN
公开(公告)号：EP0794812A2
公开(公告)日：1997-09-17
申请号：EP95942858.0
申请日：1995-11-13
申请人： MEDTRONIC, INC.
发明人： YERICH, Charles, G. , COMBS, William, J. , KLECKNER, Karen, J. , PANKEN, Eric, J. , SCHALLHORN, Richard, S. , WAHLSTRAND, John, D.
IPC分类号： A61N1
CPC分类号： A61N1/36585
摘要： A body-implantable rate-responsive cardiac pacemaker is provided with circuitry for sensing a plurality of physiologic parameters known to be indicative of a patient's metabolic demand for increased cardiac output. In one embodiment, a rate-responsive pacemaker is provided with an activity sensor for detecting the patient's level of physical activity, and is further provided with an impedance sensing circuit for detecting the patient's level of minute ventilation by monitoring cardiac impedance. A rate-response transfer function, implemented by the pacemaker's control circuitry, periodically computes a rate-responsive pacing rate as a function of the outputs from both physiologic sensing circuits. The pacemaker's pacing rate is variable within a rate range defined by predetermined (programmable) upper and lower limits. In the preferred embodiment, the influence of activity sensing and minute ventilation parameters varies in accordance with the current pacing rate. In particular, the influence of activity sensing in rate determination in accordance with the rate-response function is greater than that of minute ventilation, for slower pacing rates, while the influence of minute ventilation sensing dominates over that of activity sensing for higher pacing rates. Rate response operation of the disclosed system is recorded in the form of histogram data stored over a predetermined history time. The relative influence of the activity sensing and minute ventilation sensing on rate determination is periodically scaled or balanced based upon comparison of the histogram data with predetermined desired response data.

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