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1. 发明公开

EP2722663A4 SENSOR CHIP USED IN SPECIMEN DETECTION DEVICE AND SPECIMEN DETECTION DEVICE USING SENSOR CHIP 审中-公开
标题翻译：传感器芯片用在样品检测设备和样品检测设备符合传感器芯片
公开(公告)号：EP2722663A4
公开(公告)日：2014-11-19
申请号：EP12801279
申请日：2012-05-31
申请人： KONICA MINOLTA INC
发明人： AOKI YOUICHI
IPC分类号： G01N21/05 , G01N21/03 , G01N21/27 , G01N21/55 , G01N21/64 , G01N21/65
CPC分类号： G01N21/05 , G01N21/55 , G01N21/553 , G01N21/64 , G01N21/648 , G01N2021/0325 , G01N2021/0346
摘要： [Technical Problem] It is an object to provide a sensor chip that is used in a specimen material detection device and a specimen material detection device using a sensor chip, with which a solution can be prevented from remaining, an irregularity can be prevented from occurring in a concentration, and a fluctuation of a signal can be prevented from occurring during a detection, and as a result it is possible to carry out an inspection in an accurate manner. [Solution of Problem] A specimen material detection device is configured in such a manner that the relationship between the maximum width (a) of an inflow outflow hole and the width (b) of a flow passage is a > b, and an angle ¸ that is formed between a wall surface of the flow passage and the tangent line of the inflow outflow hole at a contact point of the inflow outflow hole and the flow passage is in the range of 90° ‰¤ ¸ ‰¤ 135°.

2. 发明公开

EP3112870A4 SENSOR CHIP FOR SURFACE PLASMON-FIELD ENHANCED FLUORESCENCE SPECTROSCOPY 有权转让
标题翻译： SENSORCHIPFÜROBERFLÄCHENPLASMONENFELDVERSTÄRKTEFLUORESZENZSPEKTROSKOPIE
公开(公告)号：EP3112870A4
公开(公告)日：2017-09-06
申请号：EP15754701
申请日：2015-01-26
申请人： KONICA MINOLTA INC
发明人： HIKAGE NAOKI , HIRAYAMA HIROSHI , WADA TAKESHI , AOKI YOUICHI
IPC分类号： G01N33/543 , G01N21/64
CPC分类号： G01N21/648
摘要： An object of the present invention is to provide a sensor chip in which non-specific adsorption of contaminants originating from a measurement sample (biological sample) to a sensor section is effectively inhibited and the effect of blocking autofluorescence emitted by a dielectric member is not reduced with time. The sensor chip of the present invention is a sensor chip for surface plasmon-field enhanced spectroscopy that includes: a dielectric member; a metal thin film formed on a main surface of the dielectric member; and a region on a part of the metal thin film, where a capturing substance that specifically captures a substance to be measured is immobilized, wherein a blocking treatment with a blocking agent is performed in a region that includes the region where the capturing substance is immobilized and the blocking treatment is not performed over the entirety of a wetted surface between a measurement sample and the metal thin film.
摘要翻译：本发明的一个目的是提供一种传感器芯片，其中源自测量样本（生物样本）的污染物对传感器部分的非特异性吸附被有效地抑制，并且阻止由电介质部件发射的自发荧光的效果没有降低随着时间的推移。本发明的传感器芯片是用于表面等离子体激元场增强光谱学的传感器芯片，其包括：电介质构件; 形成在电介质部件的主表面上的金属薄膜; 以及金属薄膜的一部分上固定有特异性地捕捉被测定物质的捕捉物质的区域，其中，在包含固定有捕捉物质的区域的区域中进行利用封闭剂的封闭处理并且不在测量样本和金属薄膜之间的整个润湿表面上执行封闭处理。

3. 发明公开

EP2708901A4 MICROCHIP LIQUID FEEDING SYSTEM 有权转让
标题翻译： MICROCHIP供液系统
公开(公告)号：EP2708901A4
公开(公告)日：2014-11-05
申请号：EP12782044
申请日：2012-05-08
申请人： KONICA MINOLTA INC
发明人： YAMAMOTO NORIAKI , AOKI YOUICHI
IPC分类号： G01N35/08 , B01L3/00 , G01N21/27 , G01N21/64 , G01N33/543 , G01N35/10 , G01N37/00
CPC分类号： G01N33/54373 , B01L3/502715 , B01L2200/0605 , B01L2300/0877 , B01L2400/0487 , G01N2035/106
摘要： [Technical Problem] It is an object to provide a microchip solution sending system that is provided with the high reaction efficiency and the high detection accuracy even in the case in which a solution amount of the specimen material solution is small. [Solution of Problem] A microchip solution sending system that is configured in such a manner that a specimen material solution (36) that has been sent passes through a detection region (20) in a repetitive manner in the case in which a micro pump (40) sends the specimen material solution (36) to a flow passage assembly (A) in a reciprocating manner; comprising a solution sending amount measurement means (42) that is configured to measure the amount of a solution that is sent from the micro pump, and a solution sending direction control means (44) that is configured to reverse the solution sending direction of the micro pump, wherein in the case in which the amount of a solution that is sent from the micro pump is measured by the solution sending amount measurement means (42) and the measured amount of the sent solution reaches a predetermined amount of the sent solution, the specimen material solution that has been sent passes through the detection region in a repetitive manner in a state in which the detection region (20) is filled with the specimen material solution (36) on a constant basis by reversing the solution sending direction by using the solution sending direction control means (44).

4. 发明公开

EP3321688A4 DETECTION DEVICE AND DETECTION METHOD 有权转让
公开(公告)号：EP3321688A4
公开(公告)日：2018-07-25
申请号：EP16821438
申请日：2016-07-06
申请人： KONICA MINOLTA INC
发明人： AOKI YOUICHI
IPC分类号： G01N35/02 , G01N1/38 , G01N21/64 , G01N33/543 , G01N35/10
CPC分类号： G01N35/04 , G01N1/38 , G01N21/64 , G01N33/543 , G01N35/02 , G01N35/10 , G01N35/1011 , G01N2035/0434 , G01N2035/103
摘要： A detection device for detecting a substance to be detected contained in a specimen has a pipette that has a detachable pipette tip and that suctions or discharges a specimen in a container, a pipette-moving unit for moving the pipette, and a control unit for controlling the pipette and pipette-moving unit. The control unit controls the pipette and the pipette-moving unit so that the pipette suctions a portion of specimen in the container with the pipette-moving unit having moved the distal end of the pipette tip to a position (a) in the lower side of the container, and thereafter discharges in the container the specimen suctioned by the pipette to stir the specimen with the pipette-moving unit having moved the distal end of the pipette tip to a position (b) above the position (a).

5. 发明公开

EP3112847A4 MEASUREMENT METHOD AND MEASUREMENT DEVICE 审中-公开
标题翻译： MESSVERFAHREN UND MESSVORICHHTUNG
公开(公告)号：EP3112847A4
公开(公告)日：2017-10-04
申请号：EP15755571
申请日：2015-02-23
申请人： KONICA MINOLTA INC
发明人： TAMURA TSURUKI , OOTANI MAKIKO , AOKI YOUICHI
IPC分类号： G01N21/64 , G01N21/552 , G01N33/543 , G01N33/553
CPC分类号： G01N21/554 , G01N21/553 , G01N21/6428 , G01N21/648 , G01N33/54373 , G01N33/553 , G01N2021/6439
摘要： With a blood-derived specimen on top of a metal film on a measurement chip, the intensity of reflected excitation light, the resonance angle of excitation light, the intensity of plasmon-scattered light, or the enhancement angle of excitation light is measured, and the acquired measurement is used to obtain a whole-blood hematocrit value. Using the obtained whole-blood hematocrit value, a first signal value that indicates how much of an analyte the specimen contains is converted to a second signal value that indicates how much of said analyte the liquid part of the specimen contains.
摘要翻译：在测量芯片上的金属膜顶部的血液来源的样本中，测量反射激发光的强度，激发光的共振角，等离子体激元散射光的强度或激发光的增强角，并且采集的测量结果用于获得全血细胞比容值。使用获得的全血细胞比容值，指示试样含有多少分析物的第一信号值被转换成第二信号值，该第二信号值指示试样的液体部分含有多少所述分析物。

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