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1. 发明授权

EP0834287B1 Neovascularization catheter 失效
标题翻译：导管血管生成
公开(公告)号：EP0834287B1
公开(公告)日：2000-12-13
申请号：EP97306105.4
申请日：1997-08-11
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Lary, Banning Gray , Radisch, Herbert R., Jr.
IPC分类号： A61B17/22 , A61B17/32
CPC分类号： A61B17/3207 , A61B17/32002 , A61B17/320725 , A61B17/320783 , A61B17/3209 , A61B17/3478 , A61B2017/00247 , A61B2017/00252 , A61B2017/22044 , A61B2017/22069 , A61B2017/22072 , A61B2018/00392

2. 发明授权

EP0707942B1 Method for manufacturing a polymeric material with enhanced mechanical properties 失效
标题翻译：一种用于具有改进的机械性能的制备聚合物材料的方法
公开(公告)号：EP0707942B1
公开(公告)日：2000-03-01
申请号：EP95303530.0
申请日：1995-05-24
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Radisch, Herbert R., Jr.
IPC分类号： B29C55/00 , B29C55/26 , B29C71/02
CPC分类号： B29C55/26 , B29C55/005 , B29K2105/24

3. 发明授权

EP0427368B1 Atherectomy system 失效
标题翻译：系统旋切术。
公开(公告)号：EP0427368B1
公开(公告)日：1995-04-05
申请号：EP90302065.9
申请日：1990-02-27
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F. , Radisch, Herbert R., Jr.
IPC分类号： A61B17/22
CPC分类号： A61B17/320758

4. 发明公开

EP0427368A1 Atherectomy system 失效
标题翻译：不知不觉间
公开(公告)号：EP0427368A1
公开(公告)日：1991-05-15
申请号：EP90302065.9
申请日：1990-02-27
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F. , Radisch, Herbert R., Jr.
IPC分类号： A61B17/22
CPC分类号： A61B17/320758
摘要： An atherectomy system (10) comprises a guide wire (110) which can be inserted into an artery (14) of a patient to a region of occlusion (12), a torque tube (218) having a cutter device (316) affixed to its distal end which is insertable into the artery over the guide wire, and a protective support sheath (418) surrounding the guide wire and the torque tube. Retraction means (410) is provided for controllably retracting the support sheath so as to allow the cutter on the distal end of the torque tube to extend progressively greater distances beyond the distal end of the support sheath. The system also includes means for rotating (22) the torque tube, thereby simultaneously rotating the cutter, and vacuum means (20) connected to the torque tube for extracting dislodged cuttings from the patient's bloodstream. The guide wire is preferably provided with an abutment (116) on its distal end which both mechanically limits the distance the cutter can advance into the patient's body and assists in retrieving the cutter from the patient's body following the atherectomy operation.
摘要翻译：动脉粥样硬化切除术系统（10）包括导丝（110），其能够插入患者的动脉（14）到闭塞区域（12）;扭矩管（218），其具有固定到其远端可插入到引导线上的动脉中，以及围绕引导线和扭矩管的保护性支撑护套（418）。提供缩回装置（410）用于可控地缩回支撑护套，以便允许转矩管的远端上的切割器延伸超出支撑护套远端的距离。该系统还包括用于旋转（22）扭矩管的装置，从而同时旋转切割器，以及连接到扭矩管的真空装置（20），用于从病人血液中提取脱落的切屑。引导线优选地在其远端设置有邻接部（116），两者都机械地限制切割器能够前进到患者体内的距离，并且有助于在动脉粥样斑块切除术后从患者身体取回刀具。

5. 发明公开

EP0834287A1 Neovascularization catheter 失效
标题翻译： Katheter zurGefässneubildung
公开(公告)号：EP0834287A1
公开(公告)日：1998-04-08
申请号：EP97306105.4
申请日：1997-08-11
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Lary, Banning Gray , Radisch, Herbert R., Jr.
IPC分类号： A61B17/22 , A61B17/32
CPC分类号： A61B17/3207 , A61B17/32002 , A61B17/320725 , A61B17/320783 , A61B17/3209 , A61B17/3478 , A61B2017/00247 , A61B2017/00252 , A61B2017/22044 , A61B2017/22069 , A61B2017/22072 , A61B2018/00392
摘要： The present invention is a device and a method for boring a perfusion channel into the myocardial tissue of a patient. Structurally, the present invention includes a positioning catheter and a cutting catheter. The positioning catheter is formed with an inflation lumen and a deployment lumen and has an inflatable balloon mounted at its distal end. The cutting catheter has a sharpened distal end and is advanceable through the deployment lumen of the positioning catheter. Advancement of the cutting catheter through the deployment lumen causes the distal end of the cutting catheter to be directed radially outward from the positioning catheter. In use, the positioning catheter is positioned within a target vessel. The inflatable balloon is then expanded to anchor the distal end of the positioning catheter. The cutting catheter is then advanced through the deployment lumen, projecting the distal end of the cutting catheter radially outward from the positioning catheter, boring a perfusion channel in the tissue adjacent to the target vessel.
摘要翻译：本发明是一种用于将灌注通道浸入患者的心肌组织的装置和方法。在结构上，本发明包括定位导管和切割导管。定位导管形成有充气腔和展开腔，并且具有安装在其远端的可充气气囊。切割导管具有锋利的远端，并且能够通过定位导管的展开腔而前进。通过展开腔导入切割导管，导致切割导管的远端从定位导管径向向外引导。在使用中，定位导管位于靶容器内。然后将可膨胀气囊膨胀以锚定定位导管的远端。切割导管然后前进通过展开腔，将切割导管的远端从定位导管径向向外突出，使邻近靶血管的组织中的灌注通道钻孔。

6. 发明授权

EP0551706B1 Atherectomy cutter with a positive attack angle 失效
标题翻译：动脉斑块旋切术铣刀正攻角
公开(公告)号：EP0551706B1
公开(公告)日：1996-02-28
申请号：EP92308135.0
申请日：1992-09-08
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Radisch, Herbert R., Jr.
IPC分类号： A61B17/22
CPC分类号： A61B17/320758

7. 发明授权

EP0554607B1 Collapsible folding angioplasty balloon 失效
标题翻译： Zusammenklapbarer球囊血管成形术
公开(公告)号：EP0554607B1
公开(公告)日：1997-11-12
申请号：EP92308260.6
申请日：1992-09-10
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F. , Radisch, Herbert R., Jr.
IPC分类号： A61M29/02
CPC分类号： A61M25/1027 , A61M25/1002 , A61M25/1038 , A61M25/104 , A61M2025/1004 , A61M2025/1084

8. 发明公开

EP0707942A3 Method for manufacturing a polymeric material with enhanced mechanical properties 失效
标题翻译： Verfahren zur Herstellung eines Polymermaterials mit verb desserten mechanischen Eigenschaften
公开(公告)号：EP0707942A3
公开(公告)日：1997-01-02
申请号：EP95303530.0
申请日：1995-05-24
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Radisch, Herbert R., Jr.
IPC分类号： B29C55/00 , B29C55/26
CPC分类号： B29C55/26 , B29C55/005 , B29K2105/24
摘要： A method of manufacturing polymeric material having enhanced structural integrity includes heating the material to a temperature between the material's glass transition temperature and the material's melt temperature. Once heated, the material is highly overstretched in a first direction and moderately overstretched in a second direction. The material is then held in the overstretched condition while it is allowed to cool to room temperature. Cooling is followed by reheating to a curing temperature. After curing for a predetermined period, the material is again allowed to cool. The completed material has high polymeric orientation in the first direction and moderate polymeric orientation in the second direction. Therefore, the material is characterized by enhanced structural integrity and absence of pinhole defects common to highly oriented polymeric materials.
摘要翻译：制造具有增强的结构完整性的聚合材料的方法包括将材料加热到材料的玻璃化转变温度和材料的熔融温度之间的温度。一旦加热，材料在第一方向上被高度过度拉伸，并在第二方向适度地过度拉伸。然后将材料保持在过度拉伸状态，同时使其冷却至室温。冷却后再加热至固化温度。固化预定时间后，再次使材料冷却。完成的材料在第一方向上具有高聚合物取向，在第二方向上具有适度的聚合物取向。因此，该材料的特征在于增强的结构完整性和高度取向的聚合物材料常见的针孔缺陷。

9. 发明公开

EP0707942A2 Method for manufacturing a polymeric material with enhanced mechanical properties 失效
标题翻译：一种用于具有改进的机械性能的制备聚合物材料的方法
公开(公告)号：EP0707942A2
公开(公告)日：1996-04-24
申请号：EP95303530.0
申请日：1995-05-24
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Radisch, Herbert R., Jr.
IPC分类号： B29C55/00 , B29C55/26
CPC分类号： B29C55/26 , B29C55/005 , B29K2105/24
摘要： A method of manufacturing polymeric material having enhanced structural integrity includes heating the material to a temperature between the material's glass transition temperature and the material's melt temperature. Once heated, the material is highly overstretched in a first direction and moderately overstretched in a second direction. The material is then held in the overstretched condition while it is allowed to cool to room temperature. Cooling is followed by reheating to a curing temperature. After curing for a predetermined period, the material is again allowed to cool. The completed material has high polymeric orientation in the first direction and moderate polymeric orientation in the second direction. Therefore, the material is characterized by enhanced structural integrity and absence of pinhole defects common to highly oriented polymeric materials.

10. 发明公开

EP0554607A1 Collapsible folding angioplasty balloon 失效
标题翻译： Zusammenklapbarer血管造影术
公开(公告)号：EP0554607A1
公开(公告)日：1993-08-11
申请号：EP92308260.6
申请日：1992-09-10
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F. , Radisch, Herbert R., Jr.
IPC分类号： A61M29/02
CPC分类号： A61M25/1027 , A61M25/1002 , A61M25/1038 , A61M25/104 , A61M2025/1004 , A61M2025/1084
摘要： An inflatable angioplasty balloon is formed in an unstressed configuration for inflation into an expanded configuration and deflation into a collapsed configuration. The balloon has a body portion (22) and two hollow end portions (24,26), with the end portions being attached to opposite ends of the body portion.
In the balloon's unstressed configuration, the body portion has three flat folding regions (42a,b,c) extending the length of the body portion. Successive folding regions are separated from each other by curved reinforcing regions (44a,b,c). The end portions are configured and oriented to guide the folding regions of the balloon into a pleated, collapsed configuration when the interior of the balloon is evacuated.
摘要翻译：可膨胀的血管成形术气囊形成为不受压力的构造，用于膨胀成扩张构型并且放气成为收缩构型。气囊具有主体部分（22）和两个中空端部部分（24,26），其端部附接到主体部分的相对端部。在气球的不受压配置中，主体部分具有延伸主体部分的长度的三个平的折叠区域（42a，b，c）。连续折叠区域通过弯曲的加强区域（44a，b，c）彼此分离。当气囊的内部被抽空时，端部被构造和定向成将气囊的折叠区域引导成打褶的折叠构型。

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