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1. 发明授权

EP0348573B1 Cutter for atherectomy device 失效转让
标题翻译：斑块切除装置切割器
公开(公告)号：EP0348573B1
公开(公告)日：1994-04-13
申请号：EP88309178.7
申请日：1988-10-03
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F. , Radisch, Herbert R. Jr.
IPC分类号： A61B17/22
CPC分类号： A61B17/320758

2. 发明公开

EP0379786A3 Atherectomy cutting device with eccentric wire 失效
标题翻译：具有中心线的自动切割装置
公开(公告)号：EP0379786A3
公开(公告)日：1991-07-17
申请号：EP89311812.5
申请日：1989-11-15
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F.
IPC分类号： A61B17/32 , A61B17/22
CPC分类号： A61B17/320758 , A61B2017/22038
摘要： An atherectomy cutting device (10) for removing obstructive tissue from the lumen (12) of a body vessel (14) comprises a guide wire (16) positionable in the lumen of the vessel, and a rotatable cutter (18) supported on an eccentric wire (20). The eccentric wire has a distal portion extension (32) establishing a substantially right angle with the eccentric wire and having a ring (34) to permit sliding movement of the eccentric wire and cutter along the guide wire. The extension and eccentric wire also permit manipulative movement of the rotatable cutter in an arc around the guide wire. There is included a dual lumen sheath (30) having a first lumen (36) for supporting the guide wire and a second lumen (38) for supporting the eccentric wire carrying the rotatable cutter. Also included is a method for removing obstructive tissue which involves manipulating the eccentric wire about the guide wire to move the cutter in an arc about the guide wire and this increase the portion of obstructive tissue contacted by the cutter.

3. 发明公开

EP0427367A1 A rotary cutting device 失效
标题翻译： Rotierende Schneidvorrichtung。
公开(公告)号：EP0427367A1
公开(公告)日：1991-05-15
申请号：EP90301576.6
申请日：1990-02-14
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F.
IPC分类号： A61B17/22
CPC分类号： A61B17/320758
摘要： A rotatable atherectomy cutter (10) for removing obstructive tissue from a body vessel includes a hollow cylindrical base (12) having an outer wall (46), a hollow cylindrical guide tip (16) coaxially distanced from the base for slidably receiving a guide wire (18) and a pair of diametrically opposed blades (14) each having a distal end and a proximal end. The distal end of each blade is connected to the guide tip and the proximal end connected to the base for alternately cutting the tissue with a first cutting edge (50) and a second cutting edge (52) longer than the first cutting edge. The proximal end of each blade is connected to an ovoid portion (40) formed in the base for allowing the second cutting edge of the blade to extend beyond the outer diameter of the cylindrical base to cut a diameter of tissue larger than the diameter of the base. The base includes a straight wall portion (54) connecting the pair of blades to establish the first cutting edge on each of the blades. The blades are inclined to the longitudinal axis of the cutter at an angle in the range of between thirty (30) and seventy (70) degrees and are preferably made of stainless steel. Also included is a mechanism for removing debris through an opening in the top of the base. The ovoid portion extends the second cutting edge of the blades beyond the outer wall a distance of approximately five (5) to ten (10) percent of the diameter of the base.
摘要翻译：一种用于从身体血管移除阻塞性组织的可旋转粥样斑块切割器（10）包括具有外壁（46）的中空圆柱形基座（12），与所述基座同轴地远离的中空圆柱形引导尖端（16），以可滑动地容纳导丝（18）和一对径向相对的叶片（14），每个叶片具有远端和近端。每个叶片的远端连接到引导尖端并且连接到基部的近端用于交替地切割具有比第一切削刃长的第一切削刃（50）和第二切削刃（52）的组织。每个叶片的近端连接到形成在基部中的卵形部分（40），用于允许叶片的第二切割刃延伸超出圆柱形基部的外径，以切割大于直径的组织的直径基础。底座包括连接该对刀片以在每个刀片上建立第一切削刃的直壁部分（54）。刀片相对于刀具的纵向轴线以三十（30）和七十（70）度之间的角度倾斜，并且优选地由不锈钢制成。还包括用于通过基座顶部的开口去除碎屑的机构。卵形部分将叶片的第二切割刃延伸超过外壁距离基部直径的大约五（5）至十（10）％的距离。

4. 发明公开

EP0379786A2 Atherectomy cutting device with eccentric wire 失效
标题翻译： SchneidegerätfürArteriektomie mit einem exzentrischen Draht。
公开(公告)号：EP0379786A2
公开(公告)日：1990-08-01
申请号：EP89311812.5
申请日：1989-11-15
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F.
IPC分类号： A61B17/32 , A61B17/22
CPC分类号： A61B17/320758 , A61B2017/22038
摘要： An atherectomy cutting device (10) for removing obstructive tissue from the lumen (12) of a body vessel (14) comprises a guide wire (16) positionable in the lumen of the vessel, and a rotatable cutter (18) supported on an eccentric wire (20). The eccentric wire has a distal portion extension (32) establishing a substantially right angle with the eccentric wire and having a ring (34) to permit sliding movement of the eccentric wire and cutter along the guide wire. The extension and eccentric wire also permit manipulative movement of the rotatable cutter in an arc around the guide wire. There is included a dual lumen sheath (30) having a first lumen (36) for supporting the guide wire and a second lumen (38) for supporting the eccentric wire carrying the rotatable cutter.
Also included is a method for removing obstructive tissue which involves manipulating the eccentric wire about the guide wire to move the cutter in an arc about the guide wire and this increase the portion of obstructive tissue contacted by the cutter.
摘要翻译：一种用于从身体容器（14）的内腔（12）去除阻塞性组织的动脉粥样组织切除切割装置（10）包括可定位在血管内腔中的导丝（16），以及可旋转切割器（18），其支撑在偏心电线（20）。偏心线具有远端部分延伸部（32），该远端部分延伸部（32）与偏心线形成大致直角并且具有环（34），以允许偏心线和切割器沿导丝滑动。延伸和偏心线还允许可旋转切割器围绕导丝围绕电弧进行操纵运动。包括具有用于支撑引导线的第一内腔（36）和用于支撑承载可旋转切割器的偏心线的第二内腔（38）的双腔护套（30）。还包括用于去除阻塞性组织的方法，其涉及围绕导丝操纵偏心线，以使围绕导丝的电弧移动切割器，并且增加了切割器接触的阻塞组织的部分。

5. 发明授权

EP0554607B1 Collapsible folding angioplasty balloon 失效
标题翻译： Zusammenklapbarer球囊血管成形术
公开(公告)号：EP0554607B1
公开(公告)日：1997-11-12
申请号：EP92308260.6
申请日：1992-09-10
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F. , Radisch, Herbert R., Jr.
IPC分类号： A61M29/02
CPC分类号： A61M25/1027 , A61M25/1002 , A61M25/1038 , A61M25/104 , A61M2025/1004 , A61M2025/1084

6. 发明公开

EP0554607A1 Collapsible folding angioplasty balloon 失效
标题翻译： Zusammenklapbarer血管造影术
公开(公告)号：EP0554607A1
公开(公告)日：1993-08-11
申请号：EP92308260.6
申请日：1992-09-10
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F. , Radisch, Herbert R., Jr.
IPC分类号： A61M29/02
CPC分类号： A61M25/1027 , A61M25/1002 , A61M25/1038 , A61M25/104 , A61M2025/1004 , A61M2025/1084
摘要： An inflatable angioplasty balloon is formed in an unstressed configuration for inflation into an expanded configuration and deflation into a collapsed configuration. The balloon has a body portion (22) and two hollow end portions (24,26), with the end portions being attached to opposite ends of the body portion.
In the balloon's unstressed configuration, the body portion has three flat folding regions (42a,b,c) extending the length of the body portion. Successive folding regions are separated from each other by curved reinforcing regions (44a,b,c). The end portions are configured and oriented to guide the folding regions of the balloon into a pleated, collapsed configuration when the interior of the balloon is evacuated.
摘要翻译：可膨胀的血管成形术气囊形成为不受压力的构造，用于膨胀成扩张构型并且放气成为收缩构型。气囊具有主体部分（22）和两个中空端部部分（24,26），其端部附接到主体部分的相对端部。在气球的不受压配置中，主体部分具有延伸主体部分的长度的三个平的折叠区域（42a，b，c）。连续折叠区域通过弯曲的加强区域（44a，b，c）彼此分离。当气囊的内部被抽空时，端部被构造和定向成将气囊的折叠区域引导成打褶的折叠构型。

7. 发明授权

EP0427368B1 Atherectomy system 失效
标题翻译：系统旋切术。
公开(公告)号：EP0427368B1
公开(公告)日：1995-04-05
申请号：EP90302065.9
申请日：1990-02-27
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F. , Radisch, Herbert R., Jr.
IPC分类号： A61B17/22
CPC分类号： A61B17/320758

8. 发明授权

EP0379786B1 Atherectomy cutting device with eccentric wire 失效
标题翻译：具有偏心线切断装置用于旋切术。
公开(公告)号：EP0379786B1
公开(公告)日：1995-03-29
申请号：EP89311812.5
申请日：1989-11-15
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F.
IPC分类号： A61B17/32 , A61B17/22
CPC分类号： A61B17/320758 , A61B2017/22038

9. 发明公开

EP0427368A1 Atherectomy system 失效
标题翻译：不知不觉间
公开(公告)号：EP0427368A1
公开(公告)日：1991-05-15
申请号：EP90302065.9
申请日：1990-02-27
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F. , Radisch, Herbert R., Jr.
IPC分类号： A61B17/22
CPC分类号： A61B17/320758
摘要： An atherectomy system (10) comprises a guide wire (110) which can be inserted into an artery (14) of a patient to a region of occlusion (12), a torque tube (218) having a cutter device (316) affixed to its distal end which is insertable into the artery over the guide wire, and a protective support sheath (418) surrounding the guide wire and the torque tube. Retraction means (410) is provided for controllably retracting the support sheath so as to allow the cutter on the distal end of the torque tube to extend progressively greater distances beyond the distal end of the support sheath. The system also includes means for rotating (22) the torque tube, thereby simultaneously rotating the cutter, and vacuum means (20) connected to the torque tube for extracting dislodged cuttings from the patient's bloodstream. The guide wire is preferably provided with an abutment (116) on its distal end which both mechanically limits the distance the cutter can advance into the patient's body and assists in retrieving the cutter from the patient's body following the atherectomy operation.
摘要翻译：动脉粥样硬化切除术系统（10）包括导丝（110），其能够插入患者的动脉（14）到闭塞区域（12）;扭矩管（218），其具有固定到其远端可插入到引导线上的动脉中，以及围绕引导线和扭矩管的保护性支撑护套（418）。提供缩回装置（410）用于可控地缩回支撑护套，以便允许转矩管的远端上的切割器延伸超出支撑护套远端的距离。该系统还包括用于旋转（22）扭矩管的装置，从而同时旋转切割器，以及连接到扭矩管的真空装置（20），用于从病人血液中提取脱落的切屑。引导线优选地在其远端设置有邻接部（116），两者都机械地限制切割器能够前进到患者体内的距离，并且有助于在动脉粥样斑块切除术后从患者身体取回刀具。

10. 发明公开

EP0348573A1 Cutter for atherectomy device 失效转让
标题翻译：斑块切除装置切割器
公开(公告)号：EP0348573A1
公开(公告)日：1990-01-03
申请号：EP88309178.7
申请日：1988-10-03
申请人： INTERVENTIONAL TECHNOLOGIES INC
发明人： Farr, Andrew F. , Radisch, Herbert R. Jr.
IPC分类号： A61B17/22
CPC分类号： A61B17/320758
摘要： A cutter (16) penetrates at its forward end into, and excises, obstructive tissue (12) in a lumen (14) in a living being by providing two spaced external segments of a conical generally hollow portion (30) with cutting surfaces at their edges. The cutter (16) may have a forward portion of restricted dimensions to facilitate the penetration of the cutter into the obstructive tissue. A progressively expanding portion such as a truncated cone extends rearwardly from the portion of restricted dimensions. In this way, the cutter expands the area of excision of the obstructive tissue from the lumen wall at progressive positions rearwardly from the forward end. The obstructive tissue in the lumen at the progressively expanding positions may be excised at the positions of penetration of the obstructive tissue by rotating the cutter manually or by a motor. The cutter may then be moved forwardly to penetrate the obstructive tissue through an additional distance in the lumen. The cutter may also have a hollow portion of substantially constant dimensions, such a hollow cylinder (26), at the laterally expanded end. This hollow cylinder is coupled to a torque tube which has strong and resilient properties to follow the contour of the lumen and to communicate a penetrating force to the forward end of the cutter and a torque to the cutter to rotate the cutter. A vacuum may be applied to the cutter through the torque tube to remove fragments of obstructive tissue excised from the lumen.
摘要翻译：切割器（16）在其前端通过提供两个间隔开的圆锥形大致中空部分（30）的外部区段而穿透活体管腔（14）中的阻塞组织（12）并切除其中的切割表面边缘。切割器（16）可以具有有限尺寸的前部以有利于切割器进入阻塞组织。逐渐扩大的部分，例如截锥，从有限尺寸的部分向后延伸。通过这种方式，切割器在前进位置处从前端向后扩展来自腔壁的阻塞组织的切除区域。通过手动或通过马达旋转切割器，可以在阻塞组织穿透的位置切除逐渐扩张位置的内腔中的阻塞组织。然后切割器可以向前移动以在内腔中穿过阻塞组织穿过另外的距离。切割器还可以具有基本上恒定尺寸的中空部分，例如在横向扩展端处的中空圆柱体（26）。该空心圆柱体连接到扭力管，该扭力管具有坚固和弹性的特性以跟随管腔的轮廓并将穿透力传递到切割器的前端以及将扭矩传递到切割器以旋转切割器。可以通过转矩管向切割器施加真空以去除从管腔切除的阻塞组织碎片。

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