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    • 1. 发明公开
    • AUTOMATIC ANALYSIS DEVICE AND DETECTION METHOD FOR MEASUREMENT VALUE ABNORMALITIES
    • AUTOMATISCHE ANALYSEVORRICHTUNG UND DETEKTIONSVERFAHRENFÜRMESSWERTANOMALIEN
    • EP2799882A4
    • 2015-08-19
    • EP12861407
    • 2012-11-22
    • HITACHI HIGH TECH CORP
    • MAKINO AKIHISAIIJIMA MASAHIKOWATANABE AKIKO
    • G01N35/00G01N21/51
    • G01N35/1002G01N21/532G01N35/00603G01N35/00663G01N35/00693G01N2035/00702Y10T436/11
    • There is provided an automatic analyzer for detecting measurement value abnormalities stemming from reaction process anomalies caused by the presence of foreign matter or bubbles without recourse to complicated processing or functionality of the analyzer. Checks for measurement value abnormalities are started to determine whether the results of concentration calculation based on light quantity data from multiple target detectors each fall within an applicable determination range (steps a, b). If the results of concentration calculation are found to fall within the determination range, an average value of the results of concentration calculation with the target detectors is calculated. If the results of concentration calculation are found to fall outside the determination range, an out-of-determination-range flag is given, and an average value of the results of concentration calculation with the target detectors is calculated (steps c, d). A default fluctuation range is retrieved regarding the average value of the results of concentration calculation. The fluctuation range of the results of concentration calculation with the multiple target detectors is calculated. It is then determined whether the calculated fluctuation range falls within the default range (steps e, f, g). If the fluctuation range is found to fall within the default range, the results of concentration calculation are output to a display unit; if the fluctuation range is found to fall outside the default range, the display unit is caused to display a reexamination request and add a measurement value abnormality alarm (steps h, i, j).
    • 提供了一种用于检测由异物或气泡的存在引起的反应过程异常产生的测量值异常的自动分析仪,而不需要分析仪的复杂处理或功能。 检查测量值异常是否开始,以确定基于来自多个目标检测器的光量数据的浓度计算的结果是否落入适用的确定范围内(步骤a,b)。 如果发现浓度计算的结果在确定范围内,则计算与目标检测器的浓度计算结果的平均值。 如果发现浓度计算的结果落在确定范围之外,则给出超出判定范围标志,并且计算与目标检测器的浓度计算结果的平均值(步骤c,d)。 根据浓度计算结果的平均值检索默认波动范围。 计算多个目标检测器的浓度计算结果的波动范围。 然后确定计算的波动范围是否在默认范围内(步骤e,f,g)。 如果发现波动范围在默认范围内,则将浓度计算的结果输出到显示单元; 如果发现波动范围超出默认范围,则显示单元显示重新检查请求并添加测量值异常警报(步骤h,i,j)。
    • 4. 发明公开
    • AUTOMATIC ANALYSIS APPARATUS
    • 自动分析装置
    • EP2860528A4
    • 2016-03-09
    • EP13804200
    • 2013-05-24
    • HITACHI HIGH TECH CORP
    • MAKINO AKIHISAYAMAZAKI HAJIMEYOSHIKAWA KEIKOANDO MANABUIIJIMA MASAHIKO
    • G01N35/02G01N21/82G01N33/86
    • G01N35/025G01N21/11G01N21/82G01N33/86G01N35/00584G01N35/00693G01N35/0092G01N35/1004G01N2021/115G01N2035/00425G01N2035/00673G01N2035/0094G01N2035/0097G01N2035/0437G01N2035/0453
    • An object of the present invention is to provide a high-throughput automatic analyzer that integrates a biochemical analysis section and a blood coagulation analysis section, the analyzer being capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk having a reaction cell arranged circumferentially thereon, the reaction cell mixing and reacting a sample and a reagent with each other, the reaction disk repeating rotation and stop; a first reagent dispensing mechanism that dispenses a reagent to the reaction cell; a photometer that irradiates a reaction solution in the reaction cell with light to thereby detect light; a reaction cell cleaning mechanism that cleans the reaction cell; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism with a reagent heating function that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to thereby detect transmitted light or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.
    • 本发明的目的是提供一种将生化分析部和血液凝固分析部进行集成的高通量自动分析装置,能够实现小型化,系统成本降低,生命周期成本的降低。 所述自动分析装置包括:反应盘,其具有周向配置的反应池,所述反应池使样品和试剂彼此混合并使反应盘反复旋转停止; 向反应池分配试剂的第一试剂分注机构; 光度计,其用光照射反应池中的反应溶液,从而检测光; 清洁反应池的反应池清洗机构; 反应容器供给单元,其供给用于使样品和试剂彼此混合和反应的一次性反应容器; 具有试剂加热功能的第二试剂分注机构,其向一次性反应容器分配试剂; 血液凝固时间测量部分,用光照射一次性反应容器中的反应溶液,从而检测透射光或散射光; 以及将样品分配到反应池和一次性反应容器的样品分配机构。