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2. 发明公开

EP2194548A8 Electronic network components and component networks utilizing biocompatible conductive adhesives for direct body fluid exposure 审中-公开
标题翻译：电子网络组件和组件网络利用生物相容性导电粘合剂直接暴露体液
公开(公告)号：EP2194548A8
公开(公告)日：2011-01-12
申请号：EP09014026.0
申请日：2009-11-10
申请人： Greatbatch Ltd.
发明人： Stevenson, Robert A. , Dabney, Warren S. , Brendel, Richard L. , Roberts, John , Frysz, Christine A.
IPC分类号： H01G4/35 , A61N1/37 , H01R13/719 , A61N1/375 , H05K3/32 , A61N1/05 , H01R13/66
CPC分类号： A61N1/37 , A61N1/0534 , A61N1/0539 , A61N1/0556 , A61N1/3718 , A61N1/375 , A61N1/3754 , H01G4/35 , H01R13/7197 , H01R2201/12 , H05K3/321 , H05K2201/0326
摘要： An implantable passive or active electronic network component or component network is provided which is suitable for prolonged direct body fluid exposure and is attachable to a conductive surface, circuit trace, lead or electrode. The electronic network component or component network includes (1) a non-conductive body of biocompatible and non-migratable material, (2) a conductive termination surface of biocompatible and non-migratable material, associated with the body, and (3) a connection material of biocompatible and non-migratable material, for conductively coupling the termination surface to the conductive surface, circuit trace, lead or electrode. The electronic network component may include a capacitor, a resistor, an inductor, a diode, a transistor, an electronic switch, a MEMs device, or a microchip. A biocompatible and non-migratable adhesive is utilized to conductively couple components of the individual components of the electronic network, such as the conductive surface, circuit trace, lead or electrode.
摘要翻译：提供了可植入的无源或有源电子网络组件或组件网络，其适合于延长直接体液暴露并且可附着到导电表面，电路迹线，引线或电极。该电子网络组件或组件网络包括（1）生物相容和不可迁移材料的非导电主体，（2）与主体相关联的生物相容和不可迁移材料的导电终止表面，以及（3）连接生物相容和不可迁移材料的材料，用于将终端表面导电耦合到导电表面，电路迹线，引线或电极。电子网络组件可以包括电容器，电阻器，电感器，二极管，晶体管，电子开关，MEMs器件或微芯片。利用生物相容且不可迁移的粘合剂来导电地耦合电子网络的各个组件的组件，例如导电表面，电路迹线，引线或电极。

3. 发明公开

EP2198914A1 Switch for turning off therapy delivery of an active implantable medical device during MRI scans 审中-公开
标题翻译：切换到关闭期间MRI检查医疗植入物的治疗传递
公开(公告)号：EP2198914A1
公开(公告)日：2010-06-23
申请号：EP09014027.8
申请日：2009-11-10
申请人： Greatbatch Ltd.
发明人： Stevenson, Robert A.
IPC分类号： A61N1/36 , A61N1/05 , A61N1/08
CPC分类号： A61N1/3718 , A61N1/086
摘要： An MRI-compatible electronic medical therapy system is provided for temporarily preventing current flow through an implanted lead wire in the presence of an induced radio frequency, magnetic, or static field. One or more normally closed switches are disposed in series between the AIMD and the one or more distal electrodes. The switch may be incorporated in the AIMD, lead wire, or within or adjacent to the electrode. The switch remains closed during normal AIMD-related therapy, but temporarily opens in the presence of an induced radio frequency, magnetic, or static field so as to prevent current flow through the electrode and lead wire. The switches prevent current from circulating that could be induced by a medical therapeutic diagnostic device, which can cause overheating of lead wires, excessive currents or temperatures and tissue damage.
摘要翻译： MRI兼容的电子医疗治疗系统提供了一种用于通过在感应射频，磁或静电场的存在暂时防止电流流到植入引线。一个或多个常闭开关设置在AIMD和所述一个或多个远侧电极之间串联。该开关可以在AIMD，引线被结合，或内或邻近的电极。开关保持正常AIMD相关治疗期间关闭，但在感应射频，磁或静电场的存在暂时打开，以防止通过电极和导线的电流流动。开关防止循环，可以由医疗治疗诊断装置，这可能会导致导线，过电流或温度和组织损伤的过热来感应电流。

4. 发明公开

EP2143466A2 Transient voltage/current protection system for electronic circuits associated with implanted leads 审中-公开
标题翻译： Einschwingspannungs- / Einschaltstromschutzsystem与植入的引线相关联的电子电路
公开(公告)号：EP2143466A2
公开(公告)日：2010-01-13
申请号：EP09008970.7
申请日：2009-07-09
申请人： Greatbatch Ltd.
发明人： Stevenson, Robert A. , Dabney, Warren S. , Truex, Buehl E. , Brainard, Scott , Halperin, Henry R. , Lardo, Albert C.
IPC分类号： A61N1/08
CPC分类号： A61N1/08 , A61N1/086 , A61N1/3718 , A61N1/3925 , A61N1/3962 , H03H1/0007 , H03H7/0107 , H03H7/1758 , H03H7/1766
摘要： A transient voltage/surge current protection system is provided for electronic circuits associated with implanted leads. In particular, a transient voltage suppressor such as a diode, a zener diode, a transorb, a surge protector, varistor components or the like, is placed in parallel with the electronic circuits to thereby divert harmful surge current and bypass the electronic circuit during an external defibrillation event or during an applied therapeutic shock, such as from an ICD.
摘要翻译：瞬时电压/电流浪涌保护系统被提供用于与植入的引线相关联的电子电路。特别地，瞬变电压抑制器：诸如二极管，齐纳二极管，一个瞬变吸收，电涌保护器，变阻器元件或类似物，被放置在平行于电子电路，从而转移有害浪涌电流和期间，在绕过所述电子电路外部除颤事件或在应用治疗性休克时，到：如从ICD。

5. 发明公开

EP2025361A1 Tank filters adaptable for placement with a guide wire, in series with the lead wires or circuits of active medical devices to enhance MRI compatibility 审中-公开
标题翻译：改进MRI兼容性，在系列与电极引线或活性的医疗设备的电路和陷波滤波器，适于接收导丝
公开(公告)号：EP2025361A1
公开(公告)日：2009-02-18
申请号：EP07021770.8
申请日：2007-11-09
申请人： Greatbatch Ltd.
发明人： Stevenson, Robert A. , Frysz, Christine , Dabney, Warren , Brendel, Richard L.
IPC分类号： A61N1/05 , A61N1/08 , A61N1/16
CPC分类号： A61N1/3754 , A61N1/05 , A61N1/056 , A61N1/0565 , A61N1/0573 , A61N1/086 , A61N1/3718 , H01G4/35 , H01G4/40 , H03H7/01 , H03H7/1766 , H03H7/1783
摘要： A tank filter is provided for a lead wire of an active medical device (AMD). The tank filter includes a capacitor in parallel with an inductor. The parallel capacitor and inductor are placed in series with the lead wire of the AMD, wherein values of capacitance and inductance are selected such that the tank filter is resonant at a selected frequency. A passageway through the tank filter permits selective slidable passage of a guide wire therethrough for locating the lead wire in an implantable position. The Q of the inductor may be relatively maximized and the Q of the capacitor may be relatively minimized to reduce the overall Q of the tank filter to attenuate current flow through the lead wire along a range of selected frequencies. In a preferred form, the tank filter is integrated into a TIP and/or RING electrode for an active implantable medical device.
摘要翻译：的罐过滤器提供了一种用于有源医疗器械（AMD）的引线。槽路滤波器包括并联的电容器与电感器处。并联电容器和电感器串联放置与AMD的引线，被选择检查电容和电感的值worin做了槽路滤波器在所选频率上谐振。通过槽路滤波器甲通道允许通过用于可植入的位置定位所述引线导丝存在的选择性滑动通道。所述电感器的Q可以是相对最大化，并且所述电容器的Q可以被最小化相对降低槽路滤波器的总Q值通过沿的范围内选择的频率的引线以衰减电流流动。在一个优选的形式中，槽路滤波器被集成到一个TIP和/或RING电极对于有源可植入医疗设备上。

6. 发明授权

EP2267894B1 Switched safety protection circuit for an AIMD system during exposure to high power electromagnetic fields 有权
公开(公告)号：EP2267894B1
公开(公告)日：2019-08-28
申请号：EP10167031.3
申请日：2010-06-23
申请人： Greatbatch Ltd.
发明人： Johnson, Robert Shawn , Dabney, Warren S. , Stevenson, Robert A. , Williams, Christopher Michael , Moschiano, Holly Noelle , Brainard, Scott
IPC分类号： H03H7/01

7. 发明授权

EP2630988B1 Composite RF current attenuator for a medical lead 有权
标题翻译： RF混合流动减速器用于医疗用电极
公开(公告)号：EP2630988B1
公开(公告)日：2017-04-19
申请号：EP13156198.7
申请日：2013-02-21
申请人： Greatbatch Ltd.
发明人： Johnson, Robert Shawn , Frustaci, Dominick J. , Dabney, Warren S. , Stevenson, Robert A. , Kondabatni, Kishore Kumar , Spaulding, Joseph , Moschiano, Holly Noelle
IPC分类号： A61N1/16 , A61N1/08 , A61N1/05 , A61N1/37
CPC分类号： A61N1/056 , A61N1/086

8. 发明公开

EP3103514A1 RF FILTER FOR AN ACTIVE IMPLANTABLE MEDICAL DEVICE (AIMD) FOR HANDLING HIGH RF POWER INDUCED IN AN ASSOCIATED IMPLANTED LEAD FROM AN EXTERNAL RF FIELD 审中-公开
标题翻译： RF滤波器FOR HIGH RF功率的在一个相关的离子注入LINE从外部RF场的有源可植入医疗器件（AIMD）HANDLING
公开(公告)号：EP3103514A1
公开(公告)日：2016-12-14
申请号：EP16175505.3
申请日：2012-03-01
申请人： Greatbatch Ltd.
发明人： Frysz, Christine , Marzano, Thomas , Roberts, John E. , Seitz, Keith W. , Johnson, Robert Shawn , Stevenson, Robert A. , Thiebolt, William , Truex, Buehl E. , Williams, Christopher M. , Woods, Jason , Brendel, Richard L. , Dabney, Warren S. , Frustaci, Dominick J.
IPC分类号： A61N1/37
CPC分类号： A61N1/08 , A61N1/05 , A61N1/3718 , A61N1/3754 , H01G4/35 , H03H1/0007
摘要： An RF filter for an active medical device (AMD), for handling RF power induced in an associated lead from an external RF field at a selected MRI frequency or range frequencies includes a capacitor having a capacitance of between 100 and 10,000 picofarads, and a temperature stable dielectric having a dielectric constant of 200 or less and a temperature coefficient of capacitance (TCC) within the range of plus 400 to minus 7112 parts per million per degree centigrade. The capacitor's dielectric loss tangent in ohms is less than five percent of the capacitor's equivalent series resistance (ESR) at the selected MRI RF frequency or range of frequencies.
摘要翻译：对于有源医疗器件（AMD）上的RF滤波器，用于在选定的MRI频率或频率范围内从外部RF场处理在相关联的导线引起的RF功率包括具有皮法100和10000之间的电容的电容器，和一个温度具有200或更小的范围内的介电常数和电容（TCC）的温度系数加400至零下7112份每百万份每摄氏度稳定的介电。在欧姆电容的电介质损耗角正切是电容器的等效串联电阻（ESR）在所选择的MRI RF频率或频率范围的小于百分之五。

9. 发明授权

EP2415499B1 Multilayer helical wave filter for medical therapeutic or diagnostic applications 有权
标题翻译：用于医学治疗或诊断应用的多层螺旋波滤波器
公开(公告)号：EP2415499B1
公开(公告)日：2016-04-06
申请号：EP11176333.0
申请日：2011-08-02
申请人： Greatbatch Ltd.
发明人： Kondabatni, Kishore Kumar , Dabney, Waren S. , Johnson, Robert Shawn , Stevenson, Robert A. , Frysz, Christine
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/086 , A61N1/3718 , H01F17/02 , H03H1/0007
摘要： A multilayer helical wave filter having a primary resonance at a selected RF diagnostic or therapeutic frequency or frequency range, includes an elongated conductor forming at least a portion of an implantable medical lead. The elongated conductor includes a first helically wound segment having at least one planar surface, a first end and a second end, which forms a first inductive component, and a second helically wound segment having at least one planar surface, a first end and a second end, which forms a second inductive element. The first and second helically wound segments are wound in the same longitudinal direction and share a common longitudinal axis. Planar surfaces of the helically wound segments face one another, and a dielectric material is disposed between the facing planar surfaces of the helically wound segments and between adjacent coils of the helically wound segments, thereby forming a capacitance.

10. 发明公开

EP2617461A1 Co-fired hermetically sealed feedthrough with alumina substrate and platinum filled via for an active implantable medical device 有权
标题翻译：密封共烧导电铝衬底与铂经由有源可植入医疗设备填充
公开(公告)号：EP2617461A1
公开(公告)日：2013-07-24
申请号：EP13151536.3
申请日：2013-01-16
申请人： Greatbatch Ltd.
发明人： Tang, Xiaohong , Thieblot, William C. , Frysz, Christine A. , Seitz, Keith W. , Stevenson, Robert A. , Brendel, Richard L. , Marzano, Thomas , Woods, Jason , Frustaci, Dominick J. , Winn, Steven W.
IPC分类号： A61N1/375 , H01G9/10
CPC分类号： A61N1/3754 , A61N1/05 , A61N1/08 , A61N1/372 , A61N1/375 , B23K35/3013 , C22C29/12 , H01G2/103 , H01G4/005 , H01G4/12 , H01G4/30 , H01G4/35 , H01G4/40 , H01R43/00 , H02G3/22 , Y10T156/1052
摘要： A co-fired hermetically sealed feedthrough is attachable to an active implantable medical device. The feedthrough comprises an alumina dielectric substrate comprising at least 96 or 99% alumina. A via hole is disposed through the alumina dielectric substrate from a body fluid side to a device side. A substantially closed pore, fritless and substantially pure platinum fill is disposed within the via hole forming a platinum filled via electrically conductive between the body fluid side and the device side. A hermetic seal is between the platinum fill and the alumina dielectric substrate, wherein the hermetic seal comprises a tortuous and mutually conformal interface between the alumina dielectric substrate and the platinum fill.
摘要翻译：共烧密封馈通是附连到有源可植入医疗器件。通过包括在包括至少96或99％的氧化铝的氧化铝介质基板的进料。通孔A通过从体液侧到装置侧的氧化铝介质基板地设置。基本上封闭的孔隙，和无玻璃料基本上纯的铂是填充通孔形成通过导电体液侧和装置侧之间填充铂内设置。甲气密密封是铂和氧化铝填充电介质基片，worin气密密封件包括在氧化铝电介质基板和铂填充物之间的曲折和相互保形界面之间。

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