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1. 发明公开

EP1660516A1 COMPOUND AND METHOD FOR ENHANCING THE CHOLESTEROL LOWERING PROPERTY OF PLANT STEROL AND STANOL ESTERS 审中-公开
标题翻译：连接及一种改善胆固醇的财产和PFLANZENSTEROL-降低-STANOLESTERN
公开(公告)号：EP1660516A1
公开(公告)日：2006-05-31
申请号：EP04783435.3
申请日：2004-09-03
申请人： University of Nebraska-Lincoln
发明人： CARR, Timothy, P.
IPC分类号： C07J9/00 , A61K31/56
CPC分类号： C07J9/00 , A61K31/56
摘要： The present invention includes a compound which combines, through esterification, the natural cholesterol lowering properties of plant sterols or stanols with the natural cholesterol lowering properties of fatty acids, more particularly a stearic acid. This combination of substances provides a synergistic lowering of cholesterol by interfering with the normal absorption of cholesterol within the gastrointestinal tract of the digestive system and may assist in avoiding unwanted side effects which are typically experienced with commonly used cholesterol lowering drugs.

2. 发明公开

EP2694543A2 SINGLE CHAIN ANTIBODIES FOR PHOTOSYNTHETIC MICROORGANISMS AND METHODS OF USE 审中-公开
标题翻译：对于照片合成微生物的单链抗体及其使用方法
公开(公告)号：EP2694543A2
公开(公告)日：2014-02-12
申请号：EP12767799.5
申请日：2012-04-07
申请人： Synaptic Research LLC , University of Nebraska Lincoln
发明人： OYLER, George A. , ROSENBERG, Julian N , WEEKS, Donald P
IPC分类号： C07K16/14 , C07K19/00 , C12N1/12 , C12R1/89
CPC分类号： C07K16/14 , C07K2317/22 , C07K2317/569 , C07K2319/00 , C07K2319/20 , C07K2319/70 , C12N1/02 , C12N1/12 , C12N1/22
摘要： A single chain antibody that binds algae is described. The single chain antibody for algae is used to capture algae onto bioactive films. The single chain antibody is also used in a chimeric construct having a substrate binding domain and a single chain antibody domain. Dimers, trimmers, and multimer constructs are also described that aid in collection of algae from liquid mixtures by causing flocculation of algae cells.

3. 发明授权

EP2609639B1 UTILISATION DE MOLECULES A CARACTERE ZWITTERIONIQUE POUR LA FORMATION D'UNE COUCHE DE TRANSPORT DE TROUS OU D'ELECTRONS 有权
标题翻译：两性离子分子用于生产LOCH或电子传输层中使用
公开(公告)号：EP2609639B1
公开(公告)日：2016-10-05
申请号：EP11755148.1
申请日：2011-08-23
申请人： Centre National de la Recherche Scientifique , Université de Strasbourg , University Of Nebraska Lincoln
发明人： DOUDIN, Bernard , BRAUNSTEIN, Pierre , ROUTABOUL, Lucie , DALMAS, Guillaume , ZHANG, Zhengzheng , DOWBEN, Peter
IPC分类号： H01L51/54 , C07C251/22 , G03G5/06
CPC分类号： H01L51/0032 , C07C251/22 , G03G5/0618 , H01L51/0051 , H01L51/105 , H01L51/441 , H01L51/5048 , H01L51/5088 , Y02E10/549 , Y02P70/521

4. 发明公开

EP3302289A1 METHOD AND DEVICE FOR COLLECTING MYCOBACTERIUM COMPLEX SPECIES FROM THE ORAL CAVITY OF A PATIENT 有权
标题翻译：用于从患者的口腔收集细菌菌株复合物的方法和装置
公开(公告)号：EP3302289A1
公开(公告)日：2018-04-11
申请号：EP16731970.6
申请日：2016-06-01
申请人： North-West University , Stellenbosch University , University of Nebraska Lincoln
发明人： GROBLER, Anne, Frederica , CRONJE, Lizl , VILJOEN, Hendrik
IPC分类号： A61B10/00 , A61K39/04
CPC分类号： A61B10/0051 , A61B2010/0061 , A61B2010/0216 , A61B2503/04 , A61B2503/06 , A61J17/001 , A61J2200/70 , G01N33/5695
摘要： This invention relates to a method and device for collecting a Mycobacterium complex species, such Mycobacterium tuberculosis (MTB) from the oral cavities of particularly children and infants. A device is provided which has a distal end and an operative end portion manufactured from a parent polymer which has been functionalised with a chemical compound having an affinity to the Mycobacterium complex species to collect same such that the presence thereof in the sample can be detected. The invention further extends to a method of preparing biological material obtained from such collected sample.

5. 发明公开

EP2609639A1 UTILISATION DE MOLECULES A CARACTERE ZWITTERIONIQUE POUR LA FORMATION D'UNE COUCHE DE TRANSPORT DE TROUS OU D'ELECTRONS 有权
标题翻译：两性离子分子用于生产LOCH或电子传输层中使用
公开(公告)号：EP2609639A1
公开(公告)日：2013-07-03
申请号：EP11755148.1
申请日：2011-08-23
申请人： Centre National de la Recherche Scientifique , Université de Strasbourg , University Of Nebraska Lincoln
发明人： DOUDIN, Bernard , BRAUNSTEIN, Pierre , ROUTABOUL, Lucie , DALMAS, Guillaume , ZHANG, Zhengzheng , DOWBEN, Peter
IPC分类号： H01L51/50 , C07C251/22 , G03G5/06
CPC分类号： H01L51/0032 , C07C251/22 , G03G5/0618 , H01L51/0051 , H01L51/105 , H01L51/441 , H01L51/5048 , H01L51/5088 , Y02E10/549 , Y02P70/521
摘要： The invention relates to the use of zwitterionic molecules for forming a hole or electron transport layer. The preferred zwitterionic molecules of the invention are derivatives of
p -benzoquinonemonoimines. The invention is useful in the field of electronic devices in particular.

6. 发明公开

EP1896650A2 PROCESS FOR THE PRODUCTION OF HIGH QUALITY FIBERS FROM WHEAT PROTEINS AND PRODUCTS MADE FROM WHEAT PROTEIN FIBERS 审中-公开
标题翻译：用于生产优质纤维小麦蛋白和麦蛋白纤维生产的商品
公开(公告)号：EP1896650A2
公开(公告)日：2008-03-12
申请号：EP06771284.4
申请日：2006-05-25
申请人： Board of Regents University of Nebraska-Lincoln
发明人： YANG, Yiqi , REDDY, Narendra , LI, Ying
IPC分类号： D06M23/00
CPC分类号： D01F4/00 , D01D1/02
摘要： The present invention provides new fibers manufactured from wheat proteins, and a method and kit for their production. The method includes dissolving one or more wheat proteins in at least one of an alkali, acid, alcohol, reducing agent, amino acid, chemical additive, or salt in ratios between about 0.5 percent and about 50 percent by weight. A spinnable solution is obtained by aging the dissolved wheat proteins at temperatures from about minus thirty degrees Celsius (-30 C) to about one hundred and fifty degrees Celsius (150 C) for approximately one to eighty hours. The dissolved wheat proteins are extruded into a coagulation bath including at least one of an alkali, acid or salt to precipitate the wheat protein fibers. Wheat protein fibers produced according to this invention are intended to be used for textiles such as apparel, carpets and home furnishings, medical and automotive textiles, composites and other fibrous applications.

7. 发明公开

EP1572869A2 PSEUDOMONAS AVR AND HOP PROTEINS, THEIR ENCODING NUCLEIC ACIDS, AND USE THEREOF 审中-公开
标题翻译： AVR假单胞菌和啤酒花的蛋白质，核酸编码及其用途
公开(公告)号：EP1572869A2
公开(公告)日：2005-09-14
申请号：EP02731248.7
申请日：2002-04-02
申请人： CORNELL RESEARCH FOUNDATION, INC. , University of Nebraska-Lincoln , KANSAS STATE UNIVERSITY RESEARCH FOUNDATION , THE INSTITUTE FOR GENOMIC RESEARCH , Boyce Thompson Institute for Plant Research Inc.
发明人： COLLMER, Alan , ALFANO, James, R. , TANG, Xiaoyan , BUELL, C., Robin , MARTIN, Gregory, B.
IPC分类号： C12N1/00
CPC分类号： C12N15/8271 , A61K38/00 , A61K48/00 , C07K14/21 , C12N15/8261 , C12N15/8281 , C12N15/8282 , C12N15/8286 , C12N2799/021 , Y02A40/146 , Y02A40/162
摘要： The present invention relates to isolated nucleic acid molecules encoding a type III-secreted bacterial protein capable of modifying a cell death pathway in a plant cell. One aspect of the present invention involves an isolated nucleic acid molecule having a nucleotide sequence that encodes the HopPtoD2 protein of Pseudomonas syringae pv. syringae DC 3000. Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are also disclosed. The nucleic acid molecules of the present invention can be used to impart disease resistance to a plant and to make a plant hypersusceptible to colonization by nonpathogenic bacteria.

8. 发明公开

EP1161546A2 TRANS-SPECIES TRANSFER OF APOPTOTIC GENES AND TRANSGENIC PLANTS DEVELOPED THEREBY 审中-公开
标题翻译：凋亡基因物种之间的传递，从而发育的转基因植物
公开(公告)号：EP1161546A2
公开(公告)日：2001-12-12
申请号：EP99971458.7
申请日：1999-10-29
申请人： University of Nebraska-Lincoln
发明人： DICKMAN, Martin, B.
IPC分类号： C12N15/82 , C07K14/47 , A01H5/00 , G01N33/68 , C12Q1/68
CPC分类号： C12N15/8283 , C07K14/4747 , C12N15/8257 , C12N15/8271 , C12N15/8282
摘要： The invention relates to trans-species transfer of apoptotic genes to plant cells, transgenic plants developed therefrom, and screening assays using these plants. The invention also relates to drug discovery screening methods utilizing transgenic plant cells. In addition, the invention relates to methods of identifying plant apoptotic pathway components utilizing non-plant proteins and nucleic acids.

9. 发明公开

EP1114188A2 HIGH RESOLUTION GENOME SCANNING 审中-公开
标题翻译：高分辨率基因组扫描
公开(公告)号：EP1114188A2
公开(公告)日：2001-07-11
申请号：EP99969451.6
申请日：1999-09-17
申请人： University of Nebraska-Lincoln
发明人： BENSON, Andrew K.,University of Nebraska-Lincoln
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6858 , C12Q1/6827 , C12Q2527/137 , C12Q2531/113
摘要： A method is disclosed for the detection of polymorphisms in a DNA sequence on nucleotide differences. DNA sequences from different sources are amplified by the polymerase chain reaction using primers based on strand biased, over represented oligonucleotide sequences and differences in the nucleotide sequences of the amplification products determined. Also disclosed are methods for the identification of individuals or the species, strain or serotype of an organism using the method of the present invention. In addition, kits are disclosed for the determination of polymorphisms using the method of the present invention. The ability to determine genetic polymorphisms has widespread application in areas such as genome mapping, genetic linkage studies, medical diagnosis, epidemiological studies, forensics and agriculture.
摘要翻译：公开了一种检测核苷酸差异的DNA序列多态性的方法。使用基于链偏向的，过度表现的寡核苷酸序列和所确定的扩增产物的核苷酸序列差异的引物，通过聚合酶链式反应扩增来自不同来源的DNA序列。还公开了使用本发明的方法鉴定个体或生物体的物种，菌株或血清型的方法。另外，公开了使用本发明的方法测定多态性的试剂盒。确定遗传多态性的能力在诸如基因组作图，遗传连锁研究，医学诊断，流行病学研究，法医学和农业等领域具有广泛的应用。

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