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1. 发明授权

EP2880154B1 PRODUCTION OF INFECTIOUS INFLUENZA VIRUSES 有权转让
公开(公告)号：EP2880154B1
公开(公告)日：2019-05-15
申请号：EP13742451.1
申请日：2013-07-29
申请人： Sanofi Pasteur SA
发明人： LEGASTELOIS, Isabelle , MEDINA, Julie , MOSTE, Catherine
IPC分类号： C12N7/02 , C12N15/85 , C12N7/00

2. 发明授权

EP2764310B1 ROTARY DRUM FOR USE IN A VACUUM FREEZE-DRYER 有权
标题翻译：转鼓FOR USE IN真空冷冻干燥器
公开(公告)号：EP2764310B1
公开(公告)日：2016-11-23
申请号：EP12769022.0
申请日：2012-10-04
申请人： Sanofi Pasteur SA
发明人： STRUSCHKA, Manfred , PLITZKO, Matthias , GEBHARD, Thomas , LUY, Bernhard
IPC分类号： F26B5/06
CPC分类号： F26B5/065 , F26B5/06 , F26B25/16

3. 发明授权

EP2764308B1 ROTARY DRUM WITH A HEATING DEVICE FOR A FREEZE-DRYER 有权
标题翻译：转鼓带有加热装置用于冻干机
公开(公告)号：EP2764308B1
公开(公告)日：2016-09-14
申请号：EP12769023.8
申请日：2012-10-04
申请人： Sanofi Pasteur SA
发明人： GEBHARD, Thomas , KAISER, Roland , PLITZKO, Matthias , STRUSCHKA, Manfred , LUY, Bernhard
IPC分类号： F26B3/30 , F26B5/06
CPC分类号： F26B3/30 , F26B5/06 , F26B11/026

4. 发明公开

EP3416683A1 ZIKA VIRUS VACCINE 审中-公开
公开(公告)号：EP3416683A1
公开(公告)日：2018-12-26
申请号：EP17706710.5
申请日：2017-02-17
申请人： CureVac AG , Sanofi Pasteur SA
发明人： PETSCH, Benjamin , JASNY, Edith , GIRERD-CHAMBAZ, Yves
IPC分类号： A61K39/12
CPC分类号： A61K39/12 , A61K2039/53 , C12N2770/24134 , C12N2830/20 , Y02A50/392
摘要： The present invention is directed to an artificial nucleic acid and to polypeptides suitable for use in treatment or prophylaxis of an infection with Zika virus or a disorder related to such an infection. In particular, the present invention concerns a Zika virus vaccine. The present invention is directed to an artificial nucleic acid, polypeptides, compositions and vaccines comprising the artificial nucleic acid or the polypeptides. The invention further concerns a method of treating or preventing a disorder or a disease, first and second medical uses of the artificial nucleic acid, polypeptides, compositions and vaccines. Further, the invention is directed to a kit, particularly to a kit of parts, comprising the artificial nucleic acid, polypeptides, compositions and vaccines.

5. 发明授权

EP2764309B1 PROCESS LINE FOR THE PRODUCTION OF FREEZE-DRIED PARTICLES 有权
标题翻译：工艺路线冷冻干燥颗粒的生产
公开(公告)号：EP2764309B1
公开(公告)日：2016-11-23
申请号：EP12769021.2
申请日：2012-10-04
申请人： Sanofi Pasteur SA
发明人： LUY, Bernhard , PLITZKO, Matthias , STRUSCHKA, Manfred
IPC分类号： F26B5/06 , A61K9/16
CPC分类号： F26B5/06 , F26B5/065
摘要： The invention relates to freeze-drying, and more specifically to the production of freeze-dried particles as bulkware. One embodiment of a process line (300) for the production of freeze-dried particles under closed conditions comprises at least the following separate devices: A spray chamber (302) for droplet generation and freeze congealing of the liquid droplets to form particles; and a bulk freeze-dryer (304) for freeze drying the particles; wherein a transfer section (308) is provided for a product transfer from the spray chamber (302) to the freeze-dryer (304), and for the production of the particles under end-to-end closed conditions each of the devices (302, 304) and of the transfer section (308) is separately adapted for closed operation.

6. 发明公开

EP2640418A4 IMMUNOGENIC COMPOSITIONS 审中-公开
标题翻译：免疫原性组合物
公开(公告)号：EP2640418A4
公开(公告)日：2015-08-12
申请号：EP11840988
申请日：2011-11-15
申请人： SANOFI PASTEUR LTD , SANOFI PASTEUR SA
发明人： GALLICHAN SCOTT , MANCEVSKI AUSRA , REVENEAU NATHALIE , SU JIN , DALENÇON FRANÇOIS , HAENSLER JEAN
IPC分类号： A61K39/118 , A61K9/107 , A61P31/04 , A61P37/04
CPC分类号： A61K39/39 , A61K9/0019 , A61K9/107 , A61K9/1075 , A61K39/118 , A61K47/44 , A61K2039/55505 , A61K2039/55511 , A61K2039/55561 , A61K2039/55566 , A61K2039/572 , A61K2039/575

7. 发明公开

EP2764310A1 ROTARY DRUM FOR USE IN A VACUUM FREEZE-DRYER 有权
标题翻译：转鼓FOR USE IN真空冷冻干燥器
公开(公告)号：EP2764310A1
公开(公告)日：2014-08-13
申请号：EP12769022.0
申请日：2012-10-04
申请人： Sanofi Pasteur SA
发明人： STRUSCHKA, Manfred , PLITZKO, Matthias , GEBHARD, Thomas , LUY, Bernhard
IPC分类号： F26B5/06
CPC分类号： F26B5/065 , F26B5/06 , F26B25/16
摘要： A rotary drum (302) for use within a vacuum chamber (212) in a vacuum freeze-dryer (204) for the bulkware production of freeze-dried particles is provided. The drum (302) is in open communication with the vacuum chamber (212) and comprises a main section (304) terminated by a front plate (306) and a rear plate (308), the rear plate (308) is adapted for connection with a rotary supporting shaft (312) for rotary support of the drum (302), and the rear plate (308) is permeable for sublimation vapor from freeze-drying the particles.

8. 发明公开

EP2764309A1 PROCESS LINE FOR THE PRODUCTION OF FREEZE-DRIED PARTICLES 有权
标题翻译：工艺路线冷冻干燥颗粒的生产
公开(公告)号：EP2764309A1
公开(公告)日：2014-08-13
申请号：EP12769021.2
申请日：2012-10-04
申请人： Sanofi Pasteur SA
发明人： LUY, Bernhard , PLITZKO, Matthias , STRUSCHKA, Manfred
IPC分类号： F26B5/06 , A61K9/16
CPC分类号： F26B5/06 , F26B5/065
摘要： The invention relates to freeze-drying, and more specifically to the production of freeze-dried particles as bulkware. One embodiment of a process line (300) for the production of freeze-dried particles under closed conditions comprises at least the following separate devices: A spray chamber (302) for droplet generation and freeze congealing of the liquid droplets to form particles; and a bulk freeze-dryer (304) for freeze drying the particles; wherein a transfer section (308) is provided for a product transfer from the spray chamber (302) to the freeze-dryer (304), and for the production of the particles under end-to-end closed conditions each of the devices (302, 304) and of the transfer section (308) is separately adapted for closed operation.

9. 发明公开

EP2668201A2 IMMUNOLOGICAL COMPOSITIONS COMPRISING HIV GP41 POLYPEPTIDE DERIVATIVES 审中-公开
标题翻译：与HIV GP41多肽衍生物免疫组合物
公开(公告)号：EP2668201A2
公开(公告)日：2013-12-04
申请号：EP12705406.2
申请日：2012-01-26
申请人： Sanofi Pasteur SA , PX' Therapeutics , Polymun Scientific Immunbiologische Forschung GmbH , Universidad de Granada
发明人： CONEJERO-LARA, Francisco , LUQUE, Irene , MATEO, Pedro Luis , WAGNER, Andreas , CLAUDE, Raphaelle , ROGER, Marie-Gaëlle , MOUZ, Nicolas , MARTIN, Christophe
IPC分类号： C07K14/005 , C07K14/16 , A61K39/21
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/21 , A61K2039/55555 , A61K2039/55572 , C07K14/08 , C07K14/15 , C07K14/155 , C07K14/16 , C12N2740/16022 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134 , C12N2740/16271
摘要： The disclosure relates to immunological compositions for vaccinating human beings against infection by the Human Immunodeficiency Virus (HIV).

10. 发明公开

EP2578974A1 Process line for the production of freeze-dried particles 审中-公开
标题翻译： Verfahrenslinie zur Herstellung von gefriergetrockneten Partikeln
公开(公告)号：EP2578974A1
公开(公告)日：2013-04-10
申请号：EP11008057.9
申请日：2011-10-05
申请人： SANOFI PASTEUR SA
发明人： Luy, Bernhard , Plitzko, Matthias , Struschka, Manfred
IPC分类号： F26B5/06
CPC分类号： F26B5/06 , F26B5/065
摘要： The invention relates to freeze-drying, and more specifically to the production of freeze-dried particles as bulkware. One embodiment of a process line (300) for the production of freeze-dried particles under closed conditions comprises at least the following separate devices: A spray chamber (302) for droplet generation and freeze congealing of the liquid droplets to form particles; and a bulk freeze-dryer (304) for freeze drying the particles; wherein a transfer section (308) is provided for a product transfer from the spray chamber (302) to the freeze-dryer (304), and for the production of the particles under end-to-end closed conditions each of the devices (302, 304) and of the transfer section (308) is separately adapted for closed operation.
摘要翻译：本发明涉及冷冻干燥，更具体地涉及作为散装物料的冷冻干燥颗粒的生产。用于在封闭条件下生产冷冻干燥颗粒的生产线（300）的一个实施方案包括至少以下分离的装置：用于液滴产生和冷冻凝结液滴以形成颗粒的喷雾室（302）和用于冷冻干燥颗粒的本体冷冻干燥器（304）其中设置有用于从所述喷雾室（302）到所述冷冻干燥器（304）的产品转移的转移部分（308），并且用于在端对端关闭条件下生产所述颗粒，每个所述装置（302 ，304）和转印部（308）分别适于闭合操作。

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