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1. 发明公开

EP0781327A4 PRODUCTION OF HYDROXYLATED FATTY ACIDS IN GENETICALLY MODIFIED PLANTS 失效
标题翻译：制造羟基脂肪酸的转基因植物
公开(公告)号：EP0781327A4
公开(公告)日：1999-12-29
申请号：EP95934442
申请日：1995-09-25
申请人： CARNEGIE INST OF WASHINGTON , MONSANTO CO
发明人： LOO FRANK J NVAN DE , SOMERVILLE CHRIS , BROUN PIERRE
IPC分类号： A01H5/00 , C12N9/02 , C12N9/04 , C12N15/09 , C12N15/29 , C12N15/82 , C12P7/64 , C12Q1/68 , C12N5/14 , C12N15/53
CPC分类号： C12N9/0071 , C12N9/0073 , C12N15/8222 , C12N15/8247
摘要： This invention relates to plant fatty acyl hydroxylases. Methods to use conserved amino acid or nucleotide sequences to obtain plant fatty acyl hydroxylases are described. Also described is the use of cDNA clones encoding a plant hydroxylase to produce a family of hydroxylated fatty acids in transgenic plants.

2. 发明公开

EP0748260A4 ION BEAM PROCESS FOR DEPOSITION OF HIGHLY ABRASION-RESISTANT COATINGS 失效
标题翻译： EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN
公开(公告)号：EP0748260A4
公开(公告)日：1998-07-15
申请号：EP95913564
申请日：1995-03-01
申请人： MONSANTO CO
发明人： KNAPP BRADLEY J , KIMOCK FRED M , PETRMICHL RUDOLPH HUGO , GALVIN NORMAN DONALD
IPC分类号： B05D3/04 , B32B7/02 , B32B9/00 , C23C14/32 , C23C16/02 , C23C16/30 , C23C16/32 , C23C16/34 , C23C16/513 , C23F4/00 , B05D3/06 , B32B7/04
CPC分类号： C23C16/30 , C23C16/0245 , C23C16/308 , C23C16/325 , C23C16/345 , C23C16/513
摘要： An ion beam deposition method is provided for manufacturing a coated substrate with improved abrasion resistance, and improved lifetime. The substrate is first chemically cleaned to remove contaminants. Secondly, the substrate is inserted into a vacuum chamber (1) on holder (3), and the air therein is evacuated via pump (2). Then the substrate surface is bombarded with energetic ions from ion beam source (4) supplied from inert (5) or reactive (6) gas inlets to assist in removing residual hydrocarbons and surface oxides, and activating the surface. After sputter-etching the surface, a protective, abrasion-resistant coating is deposited by ion beam deposition where reactive gas inlets (7, 8 and 9) may be employed. The ion beam-deposited coating may contain one or more layers. Once the chosen coating thickness is achieved, deposition is terminated, vacuum chamber pressure is increased to atmospheric pressure and the coated substrate products having improved abrasion-resistance are removed from the chamber. These coated products may be plastic sunglass lenses, ophthalmic lenses, bar codes scanner windows, and industrial wear parts needing protection from scratches and abrasion.
摘要翻译：提供了一种离子束沉积方法，用于制造具有改善的耐磨性和改善寿命的涂覆基材。根据该方法，首先对基材进行化学清洗以除去污染物。在第二步骤中，将基板插入真空室中，并将所述室中的空气抽真空。在第三步骤中，用能量离子轰击衬底表面以帮助去除残留的碳氢化合物和表面氧化物，并激活表面。改变在”INS-E ID =“INS-S-00001”>衬底表面已经被溅射蚀刻后，通过离子束沉积沉积保护性，耐磨损的涂层。离子束沉积的涂层可以包含一层或多层。一旦已经实现了所选择的涂层厚度，则终止基板上的沉积工艺，使真空室压力增加到大气压，并且从真空室中去除具有改善的耐磨性的涂覆的基底产品。本发明的涂覆产品具有塑料太阳眼镜，眼镜，条形码扫描器窗口以及必须防止划伤和磨损的工业耐磨件的用途。

4. 发明公开

EP1002067A4 STRONG EARLY SEED-SPECIFIC GENE REGULATORY REGION 失效
标题翻译：对种子的早期阶段STRONG Generegulatory区特异IS。
公开(公告)号：EP1002067A4
公开(公告)日：2004-10-27
申请号：EP98934550
申请日：1998-07-15
申请人： CARNEGIE INST OF WASHINGTON , MONSANTO CO
发明人： BROUN PIERRE , SOMERVILLE CHRIS
IPC分类号： A01H5/00 , B62K3/10 , B62M17/00 , C12N5/10 , C12N9/00 , C12N9/02 , C12N15/09 , C12N15/29 , C12N15/82 , C12N15/00 , A01H4/00 , C12N15/04 , C12N15/05 , C12N15/11
CPC分类号： C12N9/0071 , C12N9/0083 , C12N15/8222 , C12N15/8234
摘要： Nucleic acid sequences and methods for their use are described which provide for early seed-specific transcription, in order to modulate or modify expression of foreign or endogenous genes in seeds, particularly embryo cells. The method finds particular use in conjunction with modifying fatty acid production in seed tissue.

5. 发明公开

EP0939629A4 THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS 失效
标题翻译：硫醇磺酰胺ALS METALLOPROTEINASEINHIBITOREN
公开(公告)号：EP0939629A4
公开(公告)日：2002-07-17
申请号：EP97936168
申请日：1997-07-22
申请人： MONSANTO CO
发明人： DECRESCENZO GARY , ABBAS ZAHEER S , FRESKOS JOHN N , GETMAN DANIEL P , HEINTZ ROBERT M , MISCHKE BRENT V , MCDONALD JOSEPH J
IPC分类号： C07D295/12 , A61K31/18 , A61K31/195 , A61K31/215 , A61K31/36 , A61K31/40 , A61K31/445 , A61K31/47 , A61K31/495 , A61K31/505 , A61K31/535 , A61P27/00 , C07C311/16 , C07C311/17 , C07C311/29 , C07C323/25 , C07C323/31 , C07C323/32 , C07C323/49 , C07C323/58 , C07C323/60 , C07C323/67 , C07C327/30 , C07D207/48 , C07D211/96 , C07D213/42 , C07D215/36 , C07D231/20 , C07D233/61 , C07D233/64 , C07D233/84 , C07D239/46 , C07D265/30 , C07D277/28 , C07D295/13 , C07D307/54 , C07D317/62 , C07D333/20 , C07D333/24 , C07D333/34 , C07D333/36 , C07D333/38 , C07D333/40 , C07D333/62 , C07D401/12 , C07D409/04 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/12 , A61K31/21 , A61K31/22 , A61K31/38 , A61K31/415 , A61K31/44
CPC分类号： C07D295/13 , C07C311/17 , C07C311/29 , C07C323/49 , C07D207/48 , C07D211/96 , C07D213/42 , C07D317/62 , C07D409/04
摘要： This invention is directed to proteinase (protease) inhibitors, and more particularly to thiol sulfonamide inhibitors for matrix metalloproteinase 13(MMP-13), compositions of proteinase inhibitors, intermediates for the syntheses of proteinase inhibitors, processes for the preparation of proteinase inhibitors and processes for treating pathological conditions associated with phatological matrix metalloproteinase activity related to MMP-13.

6. 发明公开

EP0983267A4 AMIDOAROMATIC RING SULFONAMIDE HYDROXAMIC ACID COMPOUNDS 失效
标题翻译： WITH酰胺化的芳香环异羟肟酸磺酰胺衍生物
公开(公告)号：EP0983267A4
公开(公告)日：2001-04-11
申请号：EP98911480
申请日：1998-03-04
申请人： MONSANTO CO
发明人： HEINTZ ROBERT M , GETMAN DANIEL P , MCDONALD JOSEPH J , DECRESCENZO GARY A , HOWARD SUSAN C , ABBAS S ZAHEER
IPC分类号： C07D249/12 , A61K31/18 , A61K31/197 , A61K31/216 , A61K31/27 , A61K31/36 , A61K31/381 , A61K31/40 , A61K31/423 , A61K31/426 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/443 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/445 , A61K31/4453 , A61K31/4465 , A61K31/4545 , A61K31/535 , A61K31/5375 , A61K31/5377 , A61K31/55 , A61P1/04 , A61P7/02 , A61P7/04 , A61P9/00 , A61P9/02 , A61P9/10 , A61P13/12 , A61P17/02 , A61P19/02 , A61P19/08 , A61P25/00 , A61P25/28 , A61P27/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P43/00 , C07C311/46 , C07C323/67 , C07D207/08 , C07D209/18 , C07D209/48 , C07D211/14 , C07D211/22 , C07D213/30 , C07D213/32 , C07D213/38 , C07D213/42 , C07D213/70 , C07D213/81 , C07D213/82 , C07D215/36 , C07D233/42 , C07D233/64 , C07D235/28 , C07D239/38 , C07D239/93 , C07D241/12 , C07D257/04 , C07D263/46 , C07D263/58 , C07D265/30 , C07D271/10 , C07D277/20 , C07D277/24 , C07D277/26 , C07D277/36 , C07D277/56 , C07D277/78 , C07D285/08 , C07D285/125 , C07D295/12 , C07D295/13 , C07D295/14 , C07D295/18 , C07D307/38 , C07D307/64 , C07D307/68 , C07D307/79 , C07D309/12 , C07D317/56 , C07D317/62 , C07D333/18 , C07D333/34 , C07D333/38 , C07D333/54 , C07D401/04 , C07D401/12 , C07D405/04 , C07D409/04 , C07D409/12 , C07D413/04 , C07D413/12 , C07D417/12 , C07D471/04 , C07D513/04 , H04N7/088
CPC分类号： C07C311/46 , C07D213/42 , C07D213/82 , C07D295/13 , C07D309/12 , C07D417/12
摘要： An amidoaromatic ring sulfonamide hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed, as are a treatment process that comprises administering a contemplated amidoaromatic ring sulfonamide hydroxamic acid compound in an MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.

7. 发明公开

EP0973719A4 METHOD OF PREPARING AMINO CARBOXYLIC ACIDS 失效
标题翻译： VERFAHREN ZUR HERSTELLUNG VONAMINOCARBONSÄUREN
公开(公告)号：EP0973719A4
公开(公告)日：2000-05-17
申请号：EP98907465
申请日：1998-02-12
申请人： MONSANTO CO
发明人： STERN MICHAEL K , JOHNSON TODD J , ROGERS MICHAEL D , LEVINE JEFFREY A , MORGENSTERN DAVID A , FOBIAN YVETTE M
IPC分类号： B01J31/24 , B01J31/20 , C07B61/00 , C07C227/00 , C07C227/20 , C07C229/16 , C07C231/08 , C07C233/36 , C07C233/47 , C07C273/18 , C07C275/16 , C07D241/08 , C07D241/18 , C07D251/04 , C07D251/14 , C07F9/38 , C07F9/40 , C07F9/6509 , C07C62/00 , C07C61/09 , C07C61/10 , C07C61/24 , C07C233/00 , C07C235/00 , C07C235/06 , C07C237/00 , C07F9/22
CPC分类号： C07F9/3813 , C07C227/00 , C07C275/16 , C07D241/18 , C07D251/04 , C07D251/14
摘要： Process for the preparation of an N-acyl amino carboxylic acid by means of a carboxymethylation reaction. In this reaction, a reaction mixture is formed which contains a base pair, carbon monoxide, hydrogen and an aldehyde with the base pair conprising a carbamoyl compound and a carboxymethylation catalyst precursor. In a preferred embodiment, the carbamoyl compound and aldehyde are selected to yield an N-acyl amino carboxylic acid which is readily converted to N-(phosphonomethyl)glycine, or a salt or ester thereof.
摘要翻译：通过羧甲基化反应制备N-酰基氨基羧酸的方法。在该反应中，形成含有碱基对，一氧化碳，氢和醛的反应混合物，碱基对包含氨基甲酰基化合物和羧甲基化催化剂前体。在优选的实施方案中，选择氨基甲酰基化合物和醛以产生易于转化成N-（膦酰基甲基）甘氨酸或其盐或酯的N-酰基氨基羧酸。

8. 发明公开

EP0870250A4 HANDHELD GUI PDA WITH GPS/dGPS RECEIVER FOR COLLECTING AGRONOMIC AND GPS POSITION DATA 失效
标题翻译：用于检测农艺和GPS位置数据和图形用户界面和GPS / GPS接收器便携PDA
公开(公告)号：EP0870250A4
公开(公告)日：2000-03-15
申请号：EP96919417
申请日：1996-06-14
申请人： MONSANTO CO
发明人： CLARK LOUIS GEORGE JR , GUMMOW DONALD ROMAINE JR , VANACHT MARC
IPC分类号： G06F3/033 , H04L29/06 , H04L29/08
CPC分类号： H04L29/06 , G06F3/033 , H04L67/12 , H04L69/329
摘要： A handheld graphic user interface (GUI) personal digital assistant (PDA) computer (Figure 48, item 200) is coupled to a GPS/dGPS receiver module (Figure 49, items 212, 214) which is also compact in size to provide for the collection of data associated with position information. Additional features provided by the stored program (pages 112-275) in the PDA (200) include a nested set of menus (Figures 3-32) for preorganizing data collection, navigational functions to permit a user to navigate to a desired location with audio and visual feedback, mapping capability, overlay generation functions which further organize and display the collective data, etc.

9. 发明公开

EP0854905A4 IMPROVED WATER SOLUBLE METAL WORKING FLUIDS 失效
标题翻译： VERBESSERTEWASSERLÖSLICHEFLÜSSIGKEITENZUR METALLBEHANDLUNG
公开(公告)号：EP0854905A4
公开(公告)日：1999-12-15
申请号：EP96928010
申请日：1996-07-19
申请人： MONSANTO CO
发明人： KALOTA DENNIS J , MARTIN DAVID A , SILVERMAN DAVID C
IPC分类号： C10M149/04 , C10M173/02 , C10N40/20 , C10N40/22
CPC分类号： C10M173/02 , C10M125/10 , C10M125/24 , C10M125/26 , C10M133/44 , C10M149/14 , C10M149/18 , C10M2201/02 , C10M2201/041 , C10M2201/042 , C10M2201/062 , C10M2201/066 , C10M2201/085 , C10M2201/087 , C10M2201/10 , C10M2201/102 , C10M2201/105 , C10M2205/14 , C10M2205/16 , C10M2205/17 , C10M2207/024 , C10M2207/125 , C10M2207/129 , C10M2215/22 , C10M2215/221 , C10M2215/223 , C10M2215/225 , C10M2215/226 , C10M2215/30 , C10M2217/041 , C10M2217/042 , C10M2217/043 , C10M2217/044 , C10M2217/045 , C10M2219/068 , C10M2223/04 , C10M2223/042 , C10M2223/045 , C10N2210/01 , C10N2210/02 , C10N2210/06 , C10N2240/401 , C10N2240/402 , C10N2240/403 , C10N2240/404 , C10N2240/405 , C10N2240/406 , C10N2240/407 , C10N2240/408 , C10N2240/409 , C10N2250/02 , C10N2270/02
摘要： There are disclosed improved water-soluble metal working fluids comprising polyaspartic acid, amides and salts thereof, a corrosion inhibitor(s) and a basic additive said additive having sufficient basicity and buffering power to maintain the pH of the composition above about 8.5 and preferably above about 9. Such compositions are useful as lubricants in processes to cut, bend, grind and shape both ferrous and non-ferrous metals and tend to maintain higher pH values due to the incorporation of a basic additive. The polyaspartic acid and salts thereof are particularly advantageous in that the fluids can be easily disposed of after use without special treatment because polyaspartic acid and salts thereof are readily biodegradable.
摘要翻译：公开了改进的水溶性金属工作流体，其包含聚天冬氨酸，酰胺和其盐，缓蚀剂和碱性添加剂，所述添加剂具有足够的碱度和缓冲能力以将组合物的pH保持在约8.5以上，优选高于这种组合物在用于切割，弯曲，研磨和成型黑色金属和有色金属的方法中可用作润滑剂，并且由于加入碱性添加剂而倾向于保持较高的pH值。聚天冬氨酸及其盐是特别有利的，因为在使用后流体可以容易地被处理而没有特别的处理，因为聚天冬氨酸及其盐易于生物降解。

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