专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明公开

EP3218043A4 NON-INVASIVE AGENT APPLICATOR 审中-公开
公开(公告)号：EP3218043A4
公开(公告)日：2018-07-11
申请号：EP15858968
申请日：2015-11-12
申请人： MUPHARMA PTY LTD
发明人： UNGER HARRY , UNGER MARK , LANGELIER SEAN MICHAEL
IPC分类号： A61M37/00 , A61K39/12 , A61K41/00 , A61N1/30 , A61N7/00
CPC分类号： A61M37/0092 , A61K39/12 , A61K39/21 , A61K41/0047 , A61K2039/5256 , A61K2039/54 , A61M37/0015 , A61M2037/0007 , A61M2037/0023 , A61M2205/3344 , A61M2205/3375 , A61N1/30 , A61N7/00 , C12N7/00 , C12N2710/24021 , C12N2710/24043 , C12N2710/24143 , C12N2740/16034 , C12N2740/16071
摘要： There is disclosed systems and methods for non-invasive delivery of an agent to biological tissues. Delivery of the agent to the tissues can be by one or more modalities. In some embodiments the systems and methods use agent carrier body including a tissue contacting surface for non-invasively engaging tissues under treatment. The tissue contacting surface can be at least partly defined by a plurality of protrusions that are in fluid communication with one or more reservoirs forming part of the agent carrier body. The protrusions may extend outward from an inside of a void and terminate at said tissue contacting surface.

82. 发明公开

EP3283158A1 DRUG DELIVERY DEVICES HAVING SEPARABLE MICRONEEDLES 有权转让
标题翻译：具有可分离微胶囊的药物递送装置
公开(公告)号：EP3283158A1
公开(公告)日：2018-02-21
申请号：EP16718962.0
申请日：2016-04-18
申请人： Georgia Tech Research Corporation
发明人： MCALLISTER, Devin V. , PRAUSNITZ, Mark R. , HENRY, Sebastien
IPC分类号： A61M37/00
CPC分类号： A61M37/0015 , A61M2037/0007 , A61M2037/0023 , A61M2037/0046 , A61M2037/0061
摘要： The devices 400, 500 include microneedles 450, 550 that may be separable from the drug delivery devices, control drug release rate and/or direction, or a combination thereof. When the microneedles are separable, a force applied to the drug delivery devices may be effective to penetrate a biological tissue with the microneedles and then to separate the microneedles from the drug delivery devices. The drug delivery devices may be capable of achieving discrete periods of drug release.

83. 发明授权

EP3096832B1 SHEAR-INDUCED DERMAL INFUSION 有权
标题翻译：剪切引起的皮肤浸润
公开(公告)号：EP3096832B1
公开(公告)日：2018-02-14
申请号：EP14806757.2
申请日：2014-10-30
申请人： L'Oréal
发明人： GREZ, Joseph, W.
IPC分类号： A61H23/02 , A61B17/3205 , A61B17/32 , A61M35/00 , A61H7/00 , A61B17/00 , A61M37/00 , A45D44/00
CPC分类号： A61B17/3205 , A45D44/00 , A45D2200/20 , A61B2017/00747 , A61B2017/00761 , A61B2017/320008 , A61H7/005 , A61H23/0254 , A61H2201/149 , A61H2201/1678 , A61M35/003 , A61M37/00 , A61M2037/0007
摘要： Treatment protocols for preparing a subject's skin to receive skin formulations having one or more active materials are provided. The devices and/or methods for carrying out the treatment protocols aim to increase the skin's ability for skin formulations to penetrate or infuse into the SC layers thereof. The treatment protocol includes the application of shearing forces in order to part, tear, or form fissures only in the Stratum Corneum (SC) of the subject's skin without inducing trauma in viable skin layers below the SC. After application of shearing forces to the skin, a skin formulation can be applied to the sheared areas of skin.

84. 发明公开

EP3251722A1 MICROPROJECTION ARRAY HAVING A BENEFICIAL AGENT CONTAINING COATING AND METHOD OF FORMING THE COATING THEREON 有权
标题翻译：具有含涂层的有益剂的微喷射阵列和形成涂层的方法
公开(公告)号：EP3251722A1
公开(公告)日：2017-12-06
申请号：EP17175113.4
申请日：2002-04-20
申请人： ALZA Corporation
发明人： Cormier, Michael J , Daddona, Peter E , Johnson, Juanita A , Young, Wendy A
IPC分类号： A61M37/00
CPC分类号： A61M37/0015 , A61B17/205 , A61K9/0014 , A61K9/0021 , A61K47/42 , A61M2037/0007 , A61M2037/0023 , A61M2037/0053
摘要： A method of forming a solid coating on microprojections in a microprojection array, comprising the steps of: (a) applying a liquid composition comprising one or more beneficial agents, a biocompatible carrier and a volatile liquid to the microprojections; (b) drying said liquid composition on said microprojections; (c) optionally, repeating steps (a) and (b) one or more times, to form said solid coating on said microprojections in the microprojection array, wherein the solid coating is adapted to allow release of the one or more beneficial agents from the coating upon hydration of the coating, and wherein said liquid composition has a beneficial agent concentration of from 1% to 30% by weight, and wherein the weight ratio of all biocompatible carriers to all beneficial agents ranges from 0.2:1 to 5:1. Also provided is a device for delivering a beneficial agent through the stratum corneum, comprising a plurality of microprojections and a solid coating obtainable by the method of the invention disposed upon at least a portion of the microprojections.
摘要翻译：包括以下步骤：（a）将包含一种或多种有益物质，生物相容性载体和挥发性液体的液体组合物施加到微喷射体上;（b）在微喷射体阵列中形成固体涂层，（b）干燥所述微喷射体上的所述液体组合物; （c）任选地，重复步骤（a）和（b）一次或多次以在所述微突出物阵列中的所述微突物上形成所述固体涂层，其中所述固体涂层适于允许所述一种或多种有益试剂从并且其中所述液体组合物具有1重量％至30重量％的有益剂浓度，并且其中所有生物相容性载体与所有有益剂的重量比在0.2：1至5：1的范围内。还提供了用于通过角质层递送有益剂的装置，其包含多个微突出物和通过设置在至少一部分微突出物上的本发明方法可获得的固体涂层。

85. 发明公开

EP3247262A1 APPARATUS AND METHOD FOR SKIN TREATMENT 审中-公开
标题翻译：用于皮肤治疗的装置和方法
公开(公告)号：EP3247262A1
公开(公告)日：2017-11-29
申请号：EP16740772.5
申请日：2016-01-21
申请人： Abreu, Marcio Marc
发明人： Abreu, Marcio Marc
IPC分类号： A61B5/01 , A61B18/00 , A61B17/00 , A61B18/02 , A61B18/04 , A61F7/02 , A61K9/00
CPC分类号： A61M35/00 , A61M37/00 , A61M2037/0007
摘要： Apparatuses and methods configured to provide heat and cold to the skin along with a skin treatment to control rate of skin treatment flow to the skin are described. The disclosed apparatuses and methods include beneficially delaying the transition of skin treatments once skin penetration is achieved to improve the effectiveness of topical treatments to the skin. Accordingly, the disclosed apparatuses and methods are configured to enhance the benefits of topical treatments to the skin.

86. 发明公开

EP3236838A1 COMBINED LOCAL DELIVERY OF THERAPEUTIC AGENTS USING INTERVENTIONAL DEVICES AND RADIATION 有权
标题翻译：使用介入装置和辐射联合局部输送治疗剂
公开(公告)号：EP3236838A1
公开(公告)日：2017-11-01
申请号：EP15872073.0
申请日：2015-12-22
申请人： The University of North Carolina at Chapel Hill
发明人： DESIMONE, Joseph , TEPPER, Joel E. , BYRNE, James
IPC分类号： A61B5/00 , A61B8/00 , A61K9/00 , A61N1/30 , A61N5/00 , A61N5/10
CPC分类号： A61N5/1077 , A61M5/007 , A61M37/00 , A61M2037/0007 , A61N1/0509 , A61N1/327 , A61N5/10 , A61N5/1007 , A61N2005/1098
摘要： A method and system for combination therapy utilizing local drug delivery and radiotherapy at a target site of body tissue are provided. The delivery system comprises a source electrode adapted to be positioned proximate to a target site of internal body tissue. A counter electrode is in electrical communication with the source electrode, and 5 is configured to cooperate with the source electrode to form a localized electric field proximate to the target site. A cargo may be delivered to the target site when exposed to the localized electric field. Radiotherapy is applied to the target site in combination with the local drug delivery.
摘要翻译：提供了在身体组织的目标部位利用局部药物递送和放射疗法的联合疗法的方法和系统。输送系统包括适于定位在内部身体组织的目标部位附近的源电极。反电极与源电极电连通，并且5被配置为与源电极协作以形成接近目标部位的局部电场。当暴露于局部电场时，货物可能被运送到目标地点。结合局部给药，将放射治疗应用于目标部位。

87. 发明公开

EP2558044A4 STIFFENER FOR USE WITH A DRUG PATCH 审中-公开
标题翻译： VERSTEIFER ZUR VERWENDUNG MIT EINEM WIRKSTOFFPFLASTER
公开(公告)号：EP2558044A4
公开(公告)日：2017-10-04
申请号：EP11768561
申请日：2011-04-14
申请人： SYNERON MEDICAL LTD
发明人： ARBEL GIORA , BAR-EL YOSSI
IPC分类号： A61F13/00 , A61K9/70 , A61M35/00 , A61M37/00
CPC分类号： A61K9/7084 , A61K9/7023 , A61M35/00 , A61M2037/0007

88. 发明公开

EP3218043A2 NON-INVASIVE AGENT APPLICATOR 审中-公开
标题翻译：非侵入性应用程序
公开(公告)号：EP3218043A2
公开(公告)日：2017-09-20
申请号：EP15858968.9
申请日：2015-11-12
申请人： Mupharma Pty Ltd
发明人： UNGER, Harry , UNGER, Mark , LANGELIER, Sean Michael
IPC分类号： A61M37/00
CPC分类号： A61M37/0092 , A61K39/12 , A61K39/21 , A61K41/0047 , A61K2039/5256 , A61K2039/54 , A61M37/0015 , A61M2037/0007 , A61M2037/0023 , A61M2205/3344 , A61M2205/3375 , A61N1/30 , A61N7/00 , C12N7/00 , C12N2710/24021 , C12N2710/24043 , C12N2710/24143 , C12N2740/16034 , C12N2740/16071
摘要： There is disclosed systems and methods for non-invasive delivery of an agent to biological tissues. Delivery of the agent to the tissues can be by one or more modalities. In some embodiments the systems and methods use agent carrier body including a tissue contacting surface for non-invasively engaging tissues under treatment. The tissue contacting surface can be at least partly defined by a plurality of protrusions that are in fluid communication with one or more reservoirs forming part of the agent carrier body. The protrusions may extend outward from an inside of a void and terminate at said tissue contacting surface.
摘要翻译：公开了用于将试剂非侵入性递送至生物组织的系统和方法。药剂递送到组织可以通过一种或多种形式。在一些实施例中，所述系统和方法使用包括组织接触表面的药剂载体，用于无创地接合治疗中的组织。组织接触表面可以至少部分地由多个突起限定，所述突起与形成药剂载体主体的一部分的一个或多个储器流体连通。突起可以从空隙的内部向外延伸并终止于所述组织接触表面。

89. 发明公开

EP3181183A1 METHODS AND SYSTEMS FOR MODULATING MEDICANTS USING ACOUSTIC ENERGY 审中-公开
标题翻译：方法和系统调制药物的使用声能
公开(公告)号：EP3181183A1
公开(公告)日：2017-06-21
申请号：EP16189694.9
申请日：2008-05-07
申请人： Guided Therapy Systems, L.L.C.
发明人： MAKIN, Inder Raj S. , SLAYTON, Michael H , BARTHE, Peter G
IPC分类号： A61M37/00 , A61B8/00 , A61N7/00 , A61N7/02 , A61B90/00
CPC分类号： A61M37/0092 , A61B8/4281 , A61B2090/378 , A61M2037/0007 , A61M2205/3375 , A61N7/00 , A61N7/02 , A61N2007/0008 , A61N2007/0043 , A61N2007/0056
摘要： This invention provides methods and systems uniquely capable of enhancing medicant delivery and/or effectiveness through the use of energy to predictably disrupt membranes and mechanically and thermally modulate cells and tissues. In exemplary embodiments, the methods and systems disclosed herein are capable of modulating multiple layers of tissue. In an exemplary embodiment, the energy is acoustic energy (e.g., ultrasound). In other exemplary embodiments, the energy is photon based energy (e.g., IPL, LED, laser, white light, etc.), or other energy forms, such radio frequency electric currents, or various combinations of acoustic energy, electromagnetic energy and other energy forms or energy absorbers such as cooling. Medicants can be first introduced to the region of interest by diffusion, circulation, and/or injection. An exemplary system (14) for enhancing medicant delivery and/or effectiveness comprises a control system (20), a probe (18), and a display (22) or indicator (22) system. Imaging and/or monitoring may alternatively be coupled and/or co-housed with an ultrasound system contemplated by the present invention.
摘要翻译：本发明提供的方法和系统能够提高Medicant递送和/或有效性通过使用能量的可预测破坏膜和机械和热调节细胞和组织的唯一。在示例性的实施方案中，方法和系统盘在游离缺失能够调节组织的多层组成。在一个示例性实施例中，能量是声能（E. G.，超声）。在其它示例性实施例中，该能量是基于光子能量（例如，IPL，LED，激光，白光，等），或其它能量形式，求射频电流，或声能，电磁能和其他能源的各种组合形式或能量吸收器：如冷却。 Medicants可以首次引入的通过扩散，循环，和/或注射感兴趣的区域。示例性的系统（14）用于增强Medicant递送和/或有效性的样品包括一个控制系统（20），（18），和显示器（22）或指示器（22）系统。成像和/或监测可以可选地耦合和/或共容纳在与由本发明设想的超声系统。

90. 发明公开

EP3043860A4 SYSTEM AND METHOD FOR CONTROLLING THE IONTOPHORETIC DELIVERY OF THERAPEUTIC AGENTS BASED ON USER INHALATION 失效
标题翻译：系统和方法控制基于吸入的治疗的IOPOPHORETIC管理
公开(公告)号：EP3043860A4
公开(公告)日：2017-05-10
申请号：EP14844895
申请日：2014-09-10
申请人： INCUBE LABS LLC
发明人： IMRAN MIR , IMRAN TALAT , HASHIM MIR
IPC分类号： A61N1/32 , A61M15/00 , A61M37/00 , A61N1/04 , A61N1/30
CPC分类号： A61N1/325 , A61M2037/0007 , A61N1/0428 , A61N1/30
摘要： Embodiments of the invention provide methods for transdermal delivery of therapeutic agents for treatment of addictive cravings e.g., from nicotine. Embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into skin. A dose of agent is delivered from the assembly into skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel agent out of the assembly. During a second period, a second current having a characteristic to attract agent is used to retain agent in the assembly such that delivery of agent into skin is minimized. In particular embodiments, a dose of agent may be delivered on-demand using an input from the patient using an inhalation sensing device which mimics an inhaled form of tobacco.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式