会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 80. 发明公开
    • Method for analyzing fluid samples in substrate channels using alternating flow
    • 通过交替运动用于承载信道的液体样品的分析的方法
    • EP1419819A1
    • 2004-05-19
    • EP03104420.9
    • 2000-09-12
    • PamGene B.V.
    • Carpay, Wilhelmus, M.Papen, Roeland, F.
    • B01L3/00
    • B01L3/50857B01F5/0683B01F5/0693B01F13/0059B01F13/0071B01F2215/0409B01J2219/00891B01L3/5023B01L3/5025B01L2300/069B01L2400/0487G01N2035/106Y10S435/97Y10S435/973Y10S436/805Y10S436/81
    • A method for analyzing one or more fluid samples for the presence, amount or identity of one or more analytes optionally present said samples, comprising the steps of:

      (a) providing a device comprising one or more round wells exposing a substrate, wherein the area of the substrate exposed in the well(s) is provided with at least one binding substance specific for at least one of said analytes;
      (b) adding an amount of sample fluid to one or more of the wells of the device;
      (c) generating an alternating flow through the substrate in the wells, whereby the liquid volume of the sample is forced to pass through the channels in the substrate from the upper side of the substrate to the lower side of the substrate and back at least one time, so as to allow for a reaction between analyte present in the sample and the binding substance(s);
      (d) reading any signal generated in any of the wells from the upper side of the substrate when the fluid has passed from the upper side of the susbtrate to the lower side of the substrate and is located as a drop underneath the substrate; and
      (e) determining from said signal(s) the presence, amount and/or identity of said one or more analytes.
    • 一种用于分析一个或多个流体样本的存在,量或一种或多种分析物任选存在的所述样值的身份的方法,包括步骤:(a)提供包括一个或多个圆形的孔露出基片的装置,worin面积 在井(一个或多个)曝光的衬底的设置有用于所述分析物的至少一个的至少一个结合物质特异性的; (B)向与一个或多个所述装置的孔中的样品流体的量; (C)在通过在孔中的基板交替流产生,由此,样品的液体体积被强制从基板到基板的下侧的上侧通过在基板上的通道通过,并回至少一个 时间,以允许存在于样品中的分析物和结合物质(多个)之间的反应; (D)在读取任何从基材当流体已经从susbtrate至基板的下侧的上侧通过并位于作为底物的下方下降的上侧的孔的产生的任何信号; 从所述信号(S)的存在,量和/或所述一个或多个分析物的身份和(e)确定的挖掘。