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61. 发明公开

EP3068901A1 INTEGRATED DEVICE WITH EXTERNAL LIGHT SOURCE FOR PROBING DETECTING AND ANALYZING MOLECULES 有权转让
标题翻译：与外部光源用于探测，检测和分子分析的集成器件
公开(公告)号：EP3068901A1
公开(公告)日：2016-09-21
申请号：EP14812051.2
申请日：2014-11-17
申请人： Quantum-si Incorporated
发明人： ROTHBERG, Jonathan M. , KABIRI, Ali , SICKLER, Jason W. , GYARFAS, Brett J. , LACKEY, Jeremy , SCHMID, Gerard , CIPRIANY, Benjamin , JEWELL, Jack , WEST, Lawrence , FERRIGNO, Michael , GLENN, Paul E. , BELLOFIORE, Anthony
IPC分类号： C12Q1/68 , G01N21/64 , G01N21/77
CPC分类号： G01N21/6486 , B01L3/5085 , B01L2200/12 , B01L2300/0829 , B01L2300/0887 , B01L2300/0893 , B01L2300/168 , C12Q1/6869 , C12Q1/6874 , C12Q2521/101 , C12Q2537/157 , C12Q2563/107 , C12Q2565/607 , G01N21/64 , G01N21/645 , G01N21/6452 , G01N21/648 , G01N21/7743 , G01N21/7746 , G01N2021/6419 , G01N2021/6441 , G01N2021/6478 , G01N2201/02 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/068 , G01N2201/125 , Y10T29/49016 , C12Q2525/101
摘要： An active-source-pixel, integrated device capable of performing biomolecule detection and/or analysis, such as single-molecule nucleic acid sequencing, is described. An active pixel of the integrated device includes a sample well into which a sample to be analyzed may diffuse, an excitation source for providing excitation energy to the sample well, and a sensor configured to detect emission from the sample. The sensor may comprise two or more segments that produce a set of signals that are analyzed to differentiate between and identify tags that are attached to, or associated with, the sample. Tag differentiation may be spectral and/or temporal based. Identification of the tags may be used to detect, analyze, and/or sequence the biomolecule.

62. 发明公开

EP3065640A2 SKIN-PRINT FLUORESCENCE ANALYSIS METHOD AND APPARATUS 审中-公开
标题翻译： FOR A AUSSENBEDRUCKUNG荧光分析的方法和装置
公开(公告)号：EP3065640A2
公开(公告)日：2016-09-14
申请号：EP14796873.9
申请日：2014-11-07
申请人： Intelligent Fingerprinting Limited
发明人： EARL, Nicholas , GODFREY, Daniel Peterson , DUNTON, John , HUDSON, Mark , RUSSELL, David
IPC分类号： A61B5/117 , A61B5/145 , G01N33/50 , B01L3/00 , G01N1/31 , G01N35/00
CPC分类号： G01N33/5306 , A61B5/0071 , A61B5/1172 , A61B5/14517 , A61B5/1455 , A61B5/1491 , A61B5/4845 , A61B10/0064 , A61B2010/0009 , A61B2560/0406 , B01L3/523 , B01L3/527 , B01L2200/025 , B01L2200/026 , B01L2200/16 , B01L2300/069 , B01L2300/0832 , B01L2400/0478 , B01L2400/084 , G01N1/312 , G01N21/6428 , G01N21/645 , G01N33/54366 , G01N2001/007
摘要： A method of analysing a skin-print provided on a first surface of an optically transparent substrate. The method comprises the steps of exposing the skin-print on the first surface of the optically transparent substrate to one or more reagents selected to bind with one or more metabolites present in the skin-print; transmitting electromagnetic radiation onto the skin-print through the optically transparent substrate using a radiation source to thereby produce an optical signal of said one or more reagents and/or said one or more metabolites; and detecting an optical image of the optical signal through the optically transparent substrate using a sensor. Also a skin-print analysis apparatus and a reagent cartridge for use in carrying out the method.

63. 发明公开

EP3060901A2 OPTOCHEMISCHER SENSOR 有权
标题翻译：光电传感器
公开(公告)号：EP3060901A2
公开(公告)日：2016-08-31
申请号：EP14801907.8
申请日：2014-10-15
申请人： Tecsense GmbH
发明人： RIBITSCH, Volker , KROTTMAIER, Johannes
IPC分类号： G01N21/64 , G01N21/77 , G01J3/44 , G01N31/22 , G01J3/02
CPC分类号： G01N21/77 , G01J3/0202 , G01J3/0272 , G01J3/0291 , G01J3/4406 , G01N21/6428 , G01N21/643 , G01N21/645 , G01N21/7703 , G01N2021/6419 , G01N2021/6432 , G01N2021/6441 , G01N2021/6484 , G01N2021/7786 , G01N2021/7793 , G01N2021/7796 , G01N2201/064
摘要： The invention relates to an optochemical sensor (1) comprising a measuring element (8), which can be excited by means of light of an excitation light source (3) and which is contact with a measurement medium, a measuring arrangement, comprising at least an excitation light source (3), and a detector (4), and a covering hood (7) that separates the measuring arrangement from the measuring element (8), wherein the excitation light source (3) and the detector (4) are fastened to a base plate (2) arranged parallel to the measuring element (8), wherein the covering hood (7), the excitation light source (3), and the detector (4) are separated from each other by at least part of the material thickness of the covering hood (7), and wherein light from the excitation light source (3) hits the measuring element (8) through an optical waveguide (6) at such an angle that fluorescent light emitted by the measuring element (8) hits the detector (4) perpendicularly.
摘要翻译：光化学传感器包括由激发光源的光可激发并与待测介质接触的测量元件，以及包括至少一个激发光源和检测器的测量装置以及将测量装置与所述测量元件，其中所述激发光源和所述检测器固定到与所述测量元件平行布置的基板，所述罩，所述激发光源和所述检测器通过所述材料厚度的至少一部分彼此分离并且来自激发光源的通过光波导的光以这样的角度照射在测量元件上，使得由测量元件发射的荧光垂直照射在检测器上。

64. 发明公开

EP2856254A4 SHUTTER ASSEMBLY FOR A LUMINESCENCE-BASED SAMPLE ANALYZER 有权
标题翻译：孔结构，用于一种在发光的基于采样分析装置
公开(公告)号：EP2856254A4
公开(公告)日：2016-08-17
申请号：EP13798044
申请日：2013-05-23
申请人： SIEMENS HEALTHCARE DIAGNOSTICS
发明人： JASPERSE JEFFREY R
IPC分类号： G03B9/14 , G01N21/64 , G03B7/08 , G03B7/095 , G03B9/42
CPC分类号： G02B26/04 , G01N21/64 , G01N21/645 , G01N33/50 , G01N2201/0221 , G01N2201/0648 , G01N2201/068 , G03B9/14 , G03B11/043 , H01J43/00
摘要： A shutter assembly includes a first shutter blade having a first toothed arm extending therefrom and a first light transmitting aperture therein, and a second shutter blade positioned adjacent and parallel to the first shutter blade. The second shutter blade has a second toothed arm extending therefrom and a second light transmitting aperture therein. The first and second shutter blades are supported to allow parallel linear motion. A motor gear is disposed between, and meshed with, the first and second toothed arms such that rotation of the gear causes the first and second shutter blades to move linearly in opposite directions between an open position in which the first and second light transmitting apertures are in an overlapping relationship with respect to one another, and a closed position in which the first and second light transmitting apertures are in a non-overlapping relationship with respect to one another.

65. 发明公开

EP2875214A4 METHOD AND APPARATUS FOR ANALYZING MULTIPHASE FLUID FLOW USING A MULTIVARIATE OPTICAL ELEMENT CALCULATION DEVICE 审中-公开
标题翻译：方法和设备的多相流体流过一个MOE计算设备分析
公开(公告)号：EP2875214A4
公开(公告)日：2016-08-03
申请号：EP12881720
申请日：2012-07-23
申请人： HALLIBURTON ENERGY SERVICES INC
发明人： ARCE CIDAR MANSILLA , IRANI CYRUS ASPI , KOOL HENDRIK
IPC分类号： E21B49/08 , E21B49/00 , G01N1/20 , G01N21/31 , G01N21/85 , G01N33/28
CPC分类号： G01N21/85 , E21B47/102 , G01N1/16 , G01N1/2035 , G01N1/38 , G01N21/314 , G01N21/55 , G01N21/552 , G01N21/645 , G01N33/2823 , G01N2001/386 , G01N2021/6421 , G01N2021/8557

66. 发明公开

EP3026418A1 PARTICLE ANALYSIS DEVICE AND PARTICLE ANALYSIS METHOD 有权
标题翻译：粒子分析装置和粒子分析程序
公开(公告)号：EP3026418A1
公开(公告)日：2016-06-01
申请号：EP14829164.4
申请日：2014-06-06
申请人： Sony Corporation
发明人： TAHARA Katsutoshi
IPC分类号： G01N15/14 , G01N21/49 , G01N21/64
CPC分类号： G01N15/1429 , G01N15/1434 , G01N15/1459 , G01N21/53 , G01N21/645 , G01N2021/6491
摘要： There are provided a particle analysis apparatus and a particle analysis method that are capable of acquiring detection data with high reliability without performing high frequency superimposition.
A particle analysis apparatus is configured to include: a light irradiation unit that irradiates particles flowing within a flow path with laser light; a light detection unit that detects fluorescence or scattered light or both the fluorescence and the scattered light, the fluorescence and the scattered light being emitted from the particles irradiated with the laser light; and a signal processing unit that processes a detection signal of the fluorescence or the scattered light or detection signals of both the fluorescence and the scattered light, the fluorescence and the scattered light being output from the light detection unit, the light irradiation unit including at least a light source that generates laser, and a laser light detector that detects part of laser light emitted from the light source, the signal processing unit correcting the detection signal of the fluorescence or the scattered light or the detection signals of both the fluorescence and the scattered light, based on a detection result in the laser light detector.

67. 发明公开

EP2901151A4 DIAGNOSTIC DEVICES AND METHODS 有权转让
标题翻译：诊断仪器在VERFAHREN
公开(公告)号：EP2901151A4
公开(公告)日：2016-06-01
申请号：EP13840799
申请日：2013-09-27
申请人： ELLUME PTY LTD
发明人： PARSONS SEAN ANDREW
IPC分类号： G01N33/48 , A61B10/00 , G01N1/10 , G01N21/27 , G01N33/50
CPC分类号： G01N33/76 , A61B10/0045 , A61B10/007 , A61B2010/0006 , G01N21/55 , G01N21/6428 , G01N21/645 , G01N21/6486 , G01N21/8483 , G01N2021/6417 , G01N2021/6441 , G01N2021/7786 , G01N2201/062
摘要： Apparatus is disclosed for identifying at least a first target condition in a human or animal body. The apparatus comprises one or more test portions for identifying a first analyte in a biological sample from the body, the first analyte providing a marker of the first target condition, and a second analyte in the biological sample, the second analyte being different from the first analyte. The apparatus is configured to identify the first target condition in the body based on the identification of both the first and second analytes. In one embodiment, the first target condition is pregnancy, the first analyte is human chorionic gonadotropin (hCG) and the second analyte is luteinizing hormone (LH).
摘要翻译：公开了用于识别人或动物体内的至少第一目标条件的装置。该装置包括一个或多个测试部分，用于从身体识别生物样品中的第一分析物，第一分析物提供第一目标条件的标记物和生物样品中的第二分析物，第二分析物不同于第一分析物分析物。该装置被配置为基于第一和第二分析物的识别识别身体中的第一目标条件。在一个实施方案中，第一个目标条件是怀孕，第一个分析物是人绒毛膜促性腺激素（hCG），第二个分析物是黄体生成素（LH）。

68. 发明公开

EP3021568A1 IMAGING APPARATUS AND METHOD FOR MANUFACTURING IMAGING APPARATUS 审中-公开
标题翻译： BILDGEBUNGSVORRICHTUNG UND VERFAHREN ZUR HERSTELLUNG DER BILDGEBUNGSVORRICHTUNG
公开(公告)号：EP3021568A1
公开(公告)日：2016-05-18
申请号：EP13889078.5
申请日：2013-07-12
申请人： Hamamatsu Photonics K.K.
发明人： SATO Takayuki
IPC分类号： H04N5/225 , A61B10/00 , G01N21/01 , G01N21/64 , G06T1/00
CPC分类号： H04N5/2256 , F21K9/65 , F21Y2107/10 , G01N21/01 , G01N21/645 , G01N21/6456 , G03B15/02 , G03B15/05 , H04N5/2253 , H04N5/33
摘要： In an imaging device 1, a tilted surface 12 is formed on one surface side of a base 3, while a flexible substrate 4 arranged with light sources 5 is secured along the tilted surface 12 of the base 3, so as to adjust the optical axis of an imaging unit 6 and positions illuminated by the light sources 5. Thus, the respective optical axes of light sources 5 are regulated not individually but at once by placing the substrate 4 along the tilted surface 12, which makes it easy to adjust the illumination positions. It is also excellent in heat dissipation of the light sources 5, since the heat generated by the light sources 5 dissipates through the base 3. This enables the light sources 5 to keep their output stability favorably.
摘要翻译：在成像装置1中，在基部3的一个表面侧形成有倾斜面12，同时沿着基部3的倾斜面12固定设置有光源5的柔性基板4，以便调整光轴成像单元6和由光源5照射的位置。因此，光源5的各个光轴不是单独调节，而是通过沿着倾斜表面12放置基板4而立即调节，这使得容易调节照明位置。由于光源5产生的热量通过基座3消散，因此光源5的散热也是极好的。这使得光源5能够有效地保持其输出稳定性。

69. 发明公开

EP2990781A1 FLUOROSCENCE DETECTION APPARATUS AND FLUOROSCENCE DETECTION METHOD 审中-公开
标题翻译： FLUORESZENZNACHWEISVORRICHTUNG UND FLUORESZENZNAZWEISVERFAHREN
公开(公告)号：EP2990781A1
公开(公告)日：2016-03-02
申请号：EP15182924.9
申请日：2015-08-28
申请人： SYSMEX CORPORATION
发明人： Tagawa, Ayato
IPC分类号： G01N21/64
CPC分类号： G01N21/645 , G01J3/4406 , G01J2003/1213 , G01N21/6456 , G01N2021/6417 , G01N2021/6471
摘要： Disclosed is a fluorescence detection apparatus comprising: a photodetector that detects colors; a light filter member on the photodetector that transmits light at on or above a predefined wavelength and that cuts off light with a wavelength included in a wavelength band below the predefined wavelength, the predefined wavelength being included in a wavelength band being a sensitivity range of the photodetector; an irradiator that irradiates a fluorescent substance on the light filter member, with excitation light with a peak wavelength included in the wavelength band below the predefined wavelength; and a first correction unit that compensates for a signal of light cut off by the light filter member out of fluorescence emitted from the fluorescent substance in response to irradiation from the excitation light.
摘要翻译：公开了一种荧光检测装置，包括：检测颜色的光电检测器; 光检测器上的光过滤器构件，其在预定波长上或之上透射光并且切断具有低于预定波长的波长带中的波长的光，所述预定波长包括在波长带中，该波长带是光电探测器; 照射器，其具有包含在预定波长以下的波长带内的峰值波长的激发光，对所述滤光器部件照射荧光物质; 以及第一校正单元，其响应于来自激发光的照射，从由荧光物质发出的荧光中补偿由光过滤器构件切断的光的信号。

70. 发明公开

EP2873976A4 DETECTION SYSTEM OF TEST SUBSTANCE 审中-公开
标题翻译：检测系统的测试物质
公开(公告)号：EP2873976A4
公开(公告)日：2016-01-27
申请号：EP13814000
申请日：2013-07-02
申请人： TOPPAN PRINTING CO LTD , TOKYO INST TECH
发明人： HIRASE TAKUMI , NAKAYAMA MASATO , HANDA HIROSHI , SAKAMOTO SATOSHI , NAITO YASUYUKI
IPC分类号： G01N33/543 , G01N21/64
CPC分类号： G01N33/54326 , G01N21/6428 , G01N21/645

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