专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

51. 发明公开

EP1542020A2 Analyzer having removable holders or a centrifuge 有权
标题翻译：分析师mitlösbarenHalterung und eine Zentrifuge
公开(公告)号：EP1542020A2
公开(公告)日：2005-06-15
申请号：EP04257593.6
申请日：2004-12-07
申请人： Ortho-Clinical Diagnostics, Inc.
发明人： Thomasso, David Angelo , Jakubowicz, Raymond Francis , Barry, James Vanselow
IPC分类号： G01N35/00 , G01N35/04
CPC分类号： G01N35/00029 , G01N35/04 , G01N2035/00089 , G01N2035/00495 , G01N2035/0443 , Y10T436/111666
摘要： An analyzer, preferably a desktop analyzer, includes: a component transport system; a liquid dispense or aspirating station; a member removably located on the transport system. The removable holder includes: a probe tip dispenser; a fluid supply section for holding a sample; a test element recess for holding one or more test elements or test element holders, wherein the removable holder is configured to contain the test element recess such that a test element can be acted upon by the liquid dispense or aspirating station, while the test element is in the recess; and a measurement device to analyze a sample. Another aspect provides a removable centrifuge model on the transport system, which separates samples, such as whole blood before analysis.
摘要翻译：分析仪，优选桌面分析仪，包括：组件传送系统; 液体分配或抽吸站; 一个可移动地位于运输系统上的部件。可移除的保持器包括：探针尖端分配器; 用于保持样品的流体供应部分; 用于保持一个或多个测试元件或测试元件保持器的测试元件凹部，其中可移除的保持器构造成容纳测试元件凹部，使得测试元件可以由液体分配或抽吸站作用，而测试元件是在休息室; 以及用于分析样品的测量装置。另一方面在运输系统上提供可移除的离心机模型，其在分析之前分离样品，例如全血。

52. 发明公开

EP1436410A4 USE OF HCV CORE ANTIGEN ASSAY FOR SCREENING OF ANTI-VIRAL COMPOUNDS 审中-公开
标题翻译： HCV核心抗原检测的用于筛选杀伤病毒化合物用途
公开(公告)号：EP1436410A4
公开(公告)日：2005-04-06
申请号：EP02773541
申请日：2002-09-23
申请人： ORTHO CLINICAL DIAGNOSTICS INC , BAHL CHANDER , LEE STEPHEN , NIVEN PATRICK C , SIMMEN KENNETH A
发明人： GAGNON LAURENCE , BAHL CHANDER , LEE STEPHEN , NIVEN PATRICK C , SIMMEN KENNETH A
IPC分类号： C12N5/08 , G01N33/569 , G01N33/576 , C12Q1/06 , C12Q1/68 , G01N33/53 , G01N33/567
CPC分类号： G01N33/56983 , G01N33/5767 , G01N2333/18 , G01N2500/00 , G01N2500/04 , G01N2500/10
摘要： The present invention is directed to a simple and efficient methof for in vitro screening of antiviral drugs. In one embodiment, an immunoassay for measuring the amount of HCV core protein in an in vitro HCV replicating system is used. This method can be used for high throughput screening of drugs that can potentially be used to treat HCV infection in patients.

53. 发明公开

EP1511391A2 CAPTURE, CONCENTRATION AND QUANTITATION OF ABNORMAL PRION PROTEIN FROM BIOLOGICAL FLUIDS USING DEPTH FILTRATION 无效
标题翻译：捕捉，集中和数量化异常朊病毒生物体液中BY深层过滤
公开(公告)号：EP1511391A2
公开(公告)日：2005-03-09
申请号：EP03731344.2
申请日：2003-05-23
申请人： Ortho-Clinical Diagnostics, Inc.
发明人： VAN HOLTEN,, Robert, W., , AUTENRIETH,, Stephen, M.,
IPC分类号： A23J1/00
CPC分类号： C07K16/065 , A23J3/12 , A23L5/20 , A23L5/23 , A61L2/0017 , C07K1/34 , C07K16/34
摘要： Methods for producing biological solutions such as immunoglobulins and in particular anti-D immunoglobulin substantially free of abnormal prion protein resulting therefrom. Specifically provided are methods for aggregation of prions and depth filtration of the biological solution to capture and remove abnormal and if desired, normal prion protein. The prion protein may then be eluted from the depth filter and filter washes and concentrated sufficient for detection at limits currently required by available assays.

54. 发明公开

EP1388919A3 Support device for a ribbon cable 审中-公开
标题翻译： StützvorrichtungfürBandkabel
公开(公告)号：EP1388919A3
公开(公告)日：2005-02-09
申请号：EP03254859.6
申请日：2003-08-04
申请人： Ortho Clinical Diagnostics Inc.
发明人： Shaw, James D.
IPC分类号： H02G11/00 , B41J19/20
CPC分类号： H02G11/006 , B41J19/20 , H01B7/0892
摘要： A support for a movable ribbon cable has a length and a first end and a second end. The support includes a member having a length and a first end and a second end thereof. The first end of the member is fixed at the movable device and the second end of the member is fixed at a point. The length of the member is substantially parallel with the length of the ribbon cable and the length of the member is movable in a substantially parallel manner with the length of the ribbon cable.
摘要翻译：可移动带状电缆的支撑件具有长度，第一端和第二端。支撑件包括具有长度和第一端及其第二端的构件。构件的第一端固定在可移动装置上，并且构件的第二端固定在一点上。构件的长度基本上平行于带状电缆的长度，并且构件的长度可以与带状电缆的长度基本平行地移动。

55. 发明公开

EP1489303A2 Reducing working fluid dilution in liquid systems 失效
标题翻译： ReduzierteVerdünnung在Flüssigkeitssystemen
公开(公告)号：EP1489303A2
公开(公告)日：2004-12-22
申请号：EP04253624.3
申请日：2004-06-17
申请人： ORTHO-CLINICAL DIAGNOSTICS, INC.
发明人： Jacobs, Merrit , Ding, Zhong
IPC分类号： F04B19/00
CPC分类号： F04B19/006 , Y10T137/0318 , Y10T436/11 , Y10T436/118339 , Y10T436/119163 , Y10T436/25 , Y10T436/2575
摘要： A method of transporting a desired fluid in a channel includes: providing a working fluid to transport the desired fluid, such as a sample; providing a first segment of a first buffer fluid which is immiscible with the working fluid and the desired fluid; providing a first segment of the desired fluid; providing a second segment of a second buffer fluid which is immiscible with the working fluid and the desired fluid; providing the desired fluid to be transported and further manipulated; and transporting the desired fluid in the channel by applying a motive force to the working fluid which in turn exerts force against the desired fluid through the first and second buffer fluid. The method prevents dilution of a sample in an apparatus such as a diagnostic analyzer or an apparatus for immunohematological testing of blood. A microfluidics handling system includes a microsystem platform that has: a substrate having: a first flat, planar surface; and a second flat planar surface opposite to the first surface. The first surface includes: at least one microchannel; an optional reagent source; an optional reaction chamber; a source of motive force to transport the fluid; a working fluid in the microchannels; a first segment of a first buffer fluid which is immiscible with the working fluid and the desired fluid; a first segment of the desired fluid; a second segment of a second buffer fluid which is immiscible with the working fluid and the desired fluid; and the desired fluid to be transported and further manipulated, wherein the fluid is present in the microchannels in the order of working fluid; first buffer fluid; first segment of the desired fluid, second buffer fluid; and the desired fluid.
摘要翻译：在通道中输送所需流体的方法包括：提供工作流体以输送所需流体，例如样品; 提供与工作流体和所需流体不混溶的第一缓冲流体的第一段; 提供所需流体的第一段; 提供与工作流体和期望流体不混溶的第二缓冲流体的第二段; 提供要运输和进一步操纵的所需流体; 以及通过向所述工作流体施加动力来输送所述通道中的所需流体，所述工作流体又通过所述第一和第二缓冲流体对期望的流体施加力。该方法防止样品在诸如诊断分析仪或血液免疫血液学检测装置之类的装置中稀释。微流体处理系统包括微系统平台，该微系统平台具有：具有第一平坦平面的基板; 以及与第一表面相对的第二平坦平面。第一表面包括：至少一个微通道; 任选的试剂源; 可选的反应室; 输送流体的动力源; 微通道中的工作流体; 与工作流体和所需流体不混溶的第一缓冲流体的第一段; 所需流体的第一段; 与工作流体和所需流体不混溶的第二缓冲流体的第二段; 以及待运输和进一步操纵的期望流体，其中流体以工作流体的顺序存在于微通道中; 第一缓冲液; 所需流体的第一段，第二缓冲流体; 和所需的流体。

56. 发明公开

EP1477810A1 Analyzer having concentric rotors 有权
标题翻译： Analysegertt konzentrischen Rotoren
公开(公告)号：EP1477810A1
公开(公告)日：2004-11-17
申请号：EP04252772.1
申请日：2004-05-13
申请人： Ortho-Clinical Diagnostics, Inc.
发明人： Tomasso, David Angelo , Jakubowicz, Raymond Francis , Barry, James Vanselow
IPC分类号： G01N35/00 , G01N35/02
CPC分类号： G01N35/025 , G01N35/00029 , G01N2035/00049 , G01N2035/00089 , G01N2035/00356 , G01N2035/0455
摘要： An analyzer, preferably a desktop analyzer, includes: a first rotor for holding a test element and at least one of a sample reservoir for a sample to be analyzed, a wash reservoir, and a probe tip dispenser; a second rotor arranged concentrically with the first rotor and adapted to receive the test element from the first rotor; an incubator arranged in cooperation with the second rotor to incubate a sample disposed in the second rotor; and a measurement device to analyze a sample located in the second ring. A method of analyzing a sample includes: providing a sample in a sample reservoir and at least one test element on a first rotor; rotating the first rotor to align the sample reservoir with a liquid dispense and aspirating station; aspirating sample from the sample reservoir; rotating the first rotor to align the test element with the liquid dispense and aspirating station; dispensing the sample onto the test element; rotating the first rotor to align the test element with a test element transfer station; and transferring the test element to a second rotor. In a preferred embodiment, the method further includes incubating the test element, rotating the second rotor to bring the test element into cooperation with a measurement device, and measuring the sample with a measurement device.
摘要翻译：分析仪，优选台式分析仪，包括：用于保持测试元件的第一转子和用于待分析样品的样品容器，洗涤容器和探针尖端分配器中的至少一个; 第二转子，与所述第一转子同心地布置并且适于从所述第一转子接收所述测试元件; 培养箱，与第二转子配合配置，以孵育设置在第二转子中的样品; 以及用于分析位于第二环中的样品的测量装置。分析样品的方法包括：在样品储存器中提供样品和在第一转子上提供至少一个测试元件; 旋转第一转子以使样品储存器与液体分配和抽吸站对准; 从样品池吸取样品; 旋转第一转子以使测试元件与液体分配和抽吸站对准; 将样品分配到测试元件上; 旋转第一转子以使测试元件与测试元件传送站对准; 并将测试元件传送到第二转子。在优选实施例中，该方法还包括孵化测试元件，旋转第二转子以使测试元件与测量装置协调，并用测量装置测量样品。

57. 发明授权

EP1036847B1 Oligonucleotide primers for efficient reverse transcription of Hepatitis C Virus (HCV) RNA and methods of use thereof 有权
标题翻译：寡核苷酸引物对的丙型肝炎病毒（HCV）RNA有效的逆转录和使用它们的方法
公开(公告)号：EP1036847B1
公开(公告)日：2004-10-27
申请号：EP00300791.1
申请日：2000-02-01
申请人： Ortho-Clinical Diagnostics, Inc.
发明人： Linnen, Jeffrey M. , Gorman, Kevin M.
IPC分类号： C12Q1/70 , C12Q1/68
CPC分类号： C12Q1/707

58. 发明公开

EP1464964A2 Test element holder with a probe guide for an analyzer 有权
标题翻译： Testelemente-Halter mit Sonden-Führungfüreinen分析师
公开(公告)号：EP1464964A2
公开(公告)日：2004-10-06
申请号：EP04251934.8
申请日：2004-03-31
申请人： Ortho-Clinical Diagnostics, Inc.
发明人： Tomasso, David , Jakubowicz, Raymond , Barry, James Vanselow
IPC分类号： G01N35/04
CPC分类号： G01N35/025 , G01N2035/00089 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0446 , Y10T436/2575
摘要： A test element holder for an automated analyzer includes: a body portion for holding at least one test element; and a guide adapted to receive a probe, such as an aspirating or dispense nozzle to position the probe in a desired registration with a test element. In a preferred embodiment, the test element holder further includes a cover disposed over at least a portion of the body portion and test element and the guide comprises at least one opening in said cover. In a preferred embodiment, the analyzer is a desktop analyzer and/or a veterinary analyzer. A method of dispensing or aspirating a fluid into or onto a test element includes: providing a test element having identifying marks thereon; providing a stationary probe; providing a cover disposed over at least a portion of test element, wherein said cover has a plurality of openings adapted to receive the probe to position the probe in a desired registration with the test element; reading the identifying marks to determine which test is to be performed; and moving the test element and cover into a position to align one of the plurality of holes into alignment with the probe depending on the test to be performed.
摘要翻译：用于自动分析器的测试元件保持器包括：用于保持至少一个测试元件的主体部分; 以及适于接收探针的引导件，例如抽吸或分配喷嘴，以将探针定位成与测试元件所需的对准。在优选实施例中，测试元件保持器还包括设置在主体部分和测试元件的至少一部分上的盖，并且引导件包括在所述盖中的至少一个开口。在优选实施例中，分析仪是台式分析仪和/或兽医分析仪。将流体分配或吸入测试元件中的方法包括：提供其上具有识别标记的测试元件; 提供固定探针; 提供设置在测试元件的至少一部分上的盖，其中所述盖具有多个开口，所述多个开口适于接收所述探针以将所述探针定位成与所述测试元件的所需对准; 读取识别标记以确定要执行哪个测试; 以及根据要执行的测试，将所述测试元件和盖移动到使所述多个孔中的一个与所述探针对准的位置。

59. 发明公开

EP1355150A3 Panel of nucleic acid sequences for cancer diagnosis 审中-公开
标题翻译：核酸序列的集合的癌症的诊断
公开(公告)号：EP1355150A3
公开(公告)日：2004-08-25
申请号：EP03252023.1
申请日：2003-03-31
申请人： Ortho-Clinical Diagnostics, Inc.
发明人： Wang, Yixin
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要： A method of diagnosing cancer by identifying differential modulation of each gene (relative to the expression of the same genes in a normal population) in a combination of genes selected from two groups of genes. Gene expression portfolios and kits for employing the method are further aspects of the invention.

60. 发明公开

EP1355149A3 Assessing colorectal cancer 审中-公开
标题翻译：大肠癌的评论
公开(公告)号：EP1355149A3
公开(公告)日：2004-08-25
申请号：EP03252022.3
申请日：2003-03-31
申请人： Ortho-Clinical Diagnostics, Inc.
发明人： Wang, Yixin
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q1/6837 , C12Q2600/158
摘要： A method of assessing the presence or absence of colorectal cancer or the likely condition of a person believed to have colorectal cancer is conducted by analyzing the expression of a group of genes. Gene expression profiles in a variety of medium such as microarrays are included as are kits that contain them.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式