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41. 发明公开

EP2271416A4 SEPARATION CARTRIDGES AND METHODS FOR FABRICATION AND USE THEREOF 审中-公开
标题翻译：切割带中，方法用于生产和使用
公开(公告)号：EP2271416A4
公开(公告)日：2012-07-04
申请号：EP09733746
申请日：2009-04-27
申请人： BIOCIUS LIFE SCIENCES INC
发明人： OZBAL CAN
IPC分类号： B01D15/32 , B01D15/22 , B01D15/30 , G01N30/60
CPC分类号： B01J20/26 , B01D15/22 , B01D15/305 , B01D15/327 , B01J20/267 , B01J20/28011 , B01J20/28052 , B01J20/287 , B01J2220/52 , G01N30/6039 , G01N30/6069 , G01N30/6082 , G01N30/6091 , G01N30/7233

42. 发明授权

EP2118646B1 UMMANTELUNG FÜR MONOLITHISCHE CHROMATOGRAPHIESÄULEN 有权
标题翻译： WRAPPING单片硅
公开(公告)号：EP2118646B1
公开(公告)日：2012-06-27
申请号：EP08707134.6
申请日：2008-01-19
申请人： Merck Patent GmbH
发明人： CABRERA PEREZ, Karin , KREHER, Klaus , NEUROTH, Willi
IPC分类号： G01N30/60 , B01D15/22
CPC分类号： B01D15/22 , G01N30/6052 , G01N30/6091 , G01N2030/524 , Y10T428/239
摘要： The present invention relates to improved casings for monolithic chromatography columns, the manufacture and use thereof. The chromatography columns provided with these new casings made of PPS and carbon fibres exhibit both enhanced long-term resistance against a large variety of solvents and pressure, and permanently enhanced separating properties.

43. 发明公开

EP2315618A4 A SYSTEM AND METHOD FOR MANUFACTURING BED SUPPORTS FOR CHROMATOGRAPHY COLUMNS 审中-公开
标题翻译：用于制造床系统和方法支持色谱柱
公开(公告)号：EP2315618A4
公开(公告)日：2011-08-17
申请号：EP09810310
申请日：2009-08-26
申请人： GE HEALTHCARE BIOSCIENCE BIOPROCESS CORP
发明人： BLOMBERG JOHAN , BIELAWSKI JACEK
IPC分类号： B01D15/22 , B21D19/04 , B21D39/03 , G01N30/60
CPC分类号： G01N30/603 , B01D15/10 , B01D15/22 , B21D39/034

44. 发明公开

EP2235522A4 CHROMATOGRAPHY COLUMN AND MAINTENANCE METHOD 审中-公开
标题翻译：色谱和维护程序
公开(公告)号：EP2235522A4
公开(公告)日：2011-03-30
申请号：EP09703818
申请日：2009-01-15
申请人： GE HEALTHCARE BIO SCIENCES AB
发明人： ERIKSSON STEFAN K
IPC分类号： G01N30/60 , B01D15/22
CPC分类号： B01D15/22 , B01D15/10 , G01N30/56 , G01N30/6017 , Y10T29/49718

45. 发明授权

EP1506047B1 EQUIPMENT AND METHOD FOR SEQUENTIAL CHROMATOGRAPHIC SIMULATED MOVING BED SEPARATION 有权
标题翻译：装置和方法对于连续色谱模拟登山床分离
公开(公告)号：EP1506047B1
公开(公告)日：2011-03-23
申请号：EP03725244.2
申请日：2003-05-16
申请人： Danisco A/S
发明人： JUMPPANEN, Juho , PAANANEN, Hannu , RAVANKO, Vili , RINNE, Jukka , KUISMA, Jarmo
IPC分类号： B01D15/18 , B01D15/22 , D21C11/02
CPC分类号： C13B20/14 , B01D15/1842 , C13B20/148
摘要： The invention relates to an equipment for fractionating a solution by a sequential SMB process, which equipment comprises a feed column and one or several other columns, which include a chromatographic separation resin bed. The equipment of the invention is characterized in that the feed column consists of or comprises a compartment where the resin bed is shallower than that of one or more of the other columns of the equipment. The invention also relates to a method for fractionating a solution into two or more fractions with the equipment of the invention.

46. 发明公开

EP2204225A1 Column reactor 审中-公开
标题翻译： Säulenreaktor
公开(公告)号：EP2204225A1
公开(公告)日：2010-07-07
申请号：EP08075962.4
申请日：2008-12-22
申请人： SynChro GmbH
发明人： Baru, Valery , Baru, Michael, Dr. , Mikheev, Vadim , Arkavy, Igor
IPC分类号： B01D15/22 , G01N30/60
CPC分类号： B01D15/22 , G01N30/6021
摘要： The invention refers to a system for the synthesis of biopolymers or performing chromatography using a polymer carrier or sorbent.
The system comprises a glass tube having a cap through which two concentric inner and outer tubes are disposed. A capillary is located within the inner tube, both tubes have a bottom part forming a filter holder, a reaction volume is defined between the filter and the lower part of the glass tube, said reaction volume comprising a resin or sorbent.
The system is characterized in that it provides a weight on the top of the inner tube and/or a means for introducing a pressurized gas into an upper volume of the column so as to control the movement of the piston, thereby minimizing the dead volumes in the column.
摘要翻译：本发明涉及用于合成生物聚合物或使用聚合物载体或吸附剂进行色谱的系统。该系统包括具有盖的玻璃管，两个同心的内管和外管通过该盖配置。毛细管位于内管内，两个管都具有形成过滤器保持器的底部，在过滤器和玻璃管的下部之间限定反应体积，所述反应体积包含树脂或吸附剂。该系统的特征在于其在内管的顶部提供重物和/或用于将加压气体引入柱的上部体积的装置，以便控制活塞的运动，从而最小化死体积列。

47. 发明公开

EP2068895A4 SELECTIVE CHEMOKINE MODULATION 有权
标题翻译：选择性调节
公开(公告)号：EP2068895A4
公开(公告)日：2009-12-23
申请号：EP07808800
申请日：2007-09-11
申请人： PROPHY MED AB
发明人： BRUCE LARS , LYNGSTADAAS STAALE PETTER
IPC分类号： A61K33/24 , A61K33/08 , A61K33/32 , A61P29/00 , A61P37/02 , A61P37/04 , A61P37/06 , B01D15/10 , B01D15/20 , B01D15/22
CPC分类号： A61M1/38 , A61K9/14 , A61K33/24 , A61M1/3679 , B01J20/02 , B01J20/06
摘要： The present invention teaches the use of a metal or an oxide of a metal having a capability of reducing the amount of the chemokine IP-IO in a sample and/or reducing the production of IP-IO in cells. The metal is a metal of group 4 or 5 in the periodic table of the elements and preferably titanium. These metals and metal oxides can selectively bind IP-IO to its surface to thereby scavenge IP-IO from the surrounding medium. In addition, a metal-cell contact induces a reduction in the production of IP-IO from IP-IO producing cells. The metals and metal oxides of the present invention can therefore be used for treating and/or preventing medical conditions characterized by adverse IP-IO expression, such as inflammatory reactions.
摘要翻译：治疗或预防以10kDa干扰素-γ可诱导蛋白（IP-10）的不良表达和/或释放为特征的疾病的方法包括将由金属或金属氧化物制成的颗粒或颗粒施用于患有疾病。在患有特征在于IP-10的不良表达和/或释放的疾病的受试者中减少IP-10的方法包括向受试者施用由金属或金属氧化物制成的颗粒或颗粒。金属是元素周期表第4或5族的金属，选自钛，锆，铪，铌和钽。

48. 发明公开

EP1244507A4 CAPILLARY COLUMNS EMPLOYING MONODISPERSED PARTICLES 有权
标题翻译：单分散VEWENDENDE毛细管
公开(公告)号：EP1244507A4
公开(公告)日：2008-02-13
申请号：EP01900881
申请日：2001-01-04
申请人： WATERS INVESTMENTS LTD
发明人： MYERS PETER
IPC分类号： G01N30/60 , G01N31/20 , B01D15/08 , B01D15/20 , B01D15/22 , B01J20/281 , B01J20/283 , B01J20/285 , G01N30/26 , G01N30/52 , G01N30/56 , G01N30/58 , G01N30/88
CPC分类号： G01N30/482 , B01D15/206 , B01D15/22 , B01J20/281 , B01J2220/54 , B01J2220/84 , G01N30/52 , G01N30/6004 , G01N30/6052 , G01N30/6095 , G01N2030/521 , G01N2030/524 , G01N2030/562 , G01N2030/582
摘要： A capillary column (10) including monodispersed particles. The capillary (10) is formed using a suitable substrate, wherein two plates (12, 18) are bonded together. At least one of the plates (12, 18) includes a channel (14) where particles are housed. Particle bead positions are of defined and equivalent diameter are arranged along the longitudinal axis (16) of the housing structure. These positions are used to position packing material used to occupy the column (10). The particle beads themselves are of equivalent diameter.

49. 发明公开

EP1875224A1 METHOD FOR PREPARING MONOLITHIC SEPARATION AND REACTION MEDIA IN A SEPARATION OR REACTION CHANNEL 有权转让
标题翻译：用于生产整体式切割和反应介质中的一台断路器或反应CHANNEL
公开(公告)号：EP1875224A1
公开(公告)日：2008-01-09
申请号：EP06742517.3
申请日：2006-03-15
申请人： VRIJE UNIVERSITEIT BRUSSEL
发明人： DESMET, Gert
IPC分类号： G01N30/60 , G01N30/52 , B01J20/281 , B01D15/22 , B81B7/04
CPC分类号： B01J20/28097 , B01J19/2485 , B01J20/28014 , B01J20/28042 , B01J20/282 , B01J20/291 , B01J2220/54 , B01J2220/82 , G01N30/52 , G01N30/6069 , G01N30/6095 , G01N2030/484 , G01N2030/528 , Y10T428/24479
摘要： The invention provides a method for preparing monolithic separation and reaction media in a separation or reaction channel, characterised in that the separation or reaction channel is first provided with a micro-structured scaffold comprising scaffold skeleton elements, substantially filling the whole channel interior in a substantially uniform way prior to the application of the monolith forming solutions and methods.

50. 发明公开

EP1396721A4 A CAKY CHROMATOGRAPHIC COLUMN AND THE METHOD FOR PRODUCING IT AND ITS APPLICATIONS 有权
标题翻译：蛋糕形色谱法用于生产和及其应用
公开(公告)号：EP1396721A4
公开(公告)日：2006-02-08
申请号：EP02732319
申请日：2002-05-16
申请人： UNIV NORTHWEST
发明人： GENG XINDU , ZHANG Y INSTITUTE OF MODERN SE
IPC分类号： B01D15/20 , B01D15/22 , G01N30/56 , G01N30/60 , B01D15/08
CPC分类号： G01N30/56 , B01D15/206 , B01D15/22 , G01N30/606 , G01N2030/562
摘要： The present invention discloses a caky chromatographic column and the method for producing it and its application. The caky chromatographic column includes a chromatographic medium column with an inlet and an exit for mobile phase and chromatographic medium packed in the inner cavity of the chromatographic medium column. The rate of thickness to radial length of the said inner cavity of the chromatographic medium is less than or equal to 1. The method for producing the caky chromatographic column comprises the steps of: 1) producing a chromatographic medium column that includes upper and lower pressing plates combined together with the inlet and exit for the mobile phase and a column body with at least one side-hole, the rate of the thickness to the radial length of the inner cavity of the chromatographic medium is less than or equal to 1; 2) injecting the chromatographic medium into the inner cavity of the chromatographic medium column through the side-hole of the chromatographic column. The caky chromatographic column can be used for the separation and purification of the biomacromolecules.

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