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12. 发明公开

EP4390402A1 METHOD OF WASHING A FLUIDIC SYSTEM OF AN IN-VITRO DIAGNOSTIC ANALYZER 审中-公开
公开(公告)号：EP4390402A1
公开(公告)日：2024-06-26
申请号：EP22214420.6
申请日：2022-12-19
申请人： F. Hoffmann-La Roche AG , Roche Diagnostics GmbH
发明人： MARTIN, Thomas
IPC分类号： G01N35/10
CPC分类号： G01N35/1004
摘要： An automated method of washing a fluidic system 210 of an IVD analyzer 200 from a previous fluid is disclosed, the fluidic system 210 comprising at least one fluidic path 211, 213, 215. The method comprises controlling by a controller 250 a pump 240 and at least one fluid-selection valve 230 for pumping a wash fluid 221 and/or air 232 through the at least one fluidic path, wherein in a time-priority mode 10 the method comprises pumping at higher speed air, in a first step 11, in order to remove the previous fluid from the at least one fluidic path, and wash-fluid plugs alternated to air plugs, in a second step 12, in order to wash out residuals of the previous fluid, and wherein in a wash-fluid-priority mode 20 the controller 250 is configured to operate according to either a sample-wash mode 30 if the previous fluid is a sample 2 or according to an other-fluid-wash mode 40 if the previous fluid is any fluid other than a sample 2, wherein in the sample-wash mode 30 the method comprises pumping air at lower speed, in a first step 31, in order to remove the previous fluid from the at least one fluidic path, pumping at least one wash-fluid plug at higher speed, in a second step 32, and pumping wash-fluid plugs alternated to air plugs at lower speed, in a third step 33, in order to wash out residuals of the previous fluid, and wherein in the other-fluid-wash mode 40 the method comprises pumping air at lower speed, in a first step 41, in order to remove the previous fluid from the at least one fluidic path and pumping wash-fluid plugs alternated to air plugs at lower speed, in a second step 42, in order to wash out residuals of the previous fluid.

13. 发明公开

EP4388075A1 APPARATUS FOR MICROSCOPIC WORM OBSERVATION 审中-公开
公开(公告)号：EP4388075A1
公开(公告)日：2024-06-26
申请号：EP22764796.3
申请日：2022-08-16
申请人： Nagi Bioscience SA
发明人： CORNAGLIA, Matteo , TACHE, Fabien
IPC分类号： C12M3/06 , C12M1/00 , C12M1/34 , G01N33/50 , G01N35/10
CPC分类号： C12M23/16 , C12M41/36 , C12M23/40 , C12M41/14 , G01N33/5085 , G01N2333/4353420130101 , G01N33/5014 , G01N2035/0052420130101 , G01N2035/0035620130101

14. 发明公开

EP4386390A1 DETERMINING PHYSICAL PARAMETERS OF A LIQUID 审中-公开
公开(公告)号：EP4386390A1
公开(公告)日：2024-06-19
申请号：EP23211693.9
申请日：2023-11-23
申请人： Tecan Trading AG
发明人： KELLER, Michael , GEIGES, Thomas , VILAJ, Volfgang
IPC分类号： G01N35/10 , G01N13/02 , G01N11/08
CPC分类号： G01N2035/106220130101 , G01N2035/10320130101 , G01N35/1016 , G01N2013/020820130101 , G01N13/02 , G01N11/08 , G01N2013/024120130101 , G01N2013/026620130101
摘要： A method for determining physical parameters of a liquid (22) to be aspirated and/or dispensed by a laboratory automation device (10) comprises: pickup of a pipette (14) with the laboratory automation device (10); lowering the pipette (14) into a sample container (18) with the laboratory automation device (10), the sample container (18) containing the liquid (22); aspirating and dispensing air and liquid (22) with the laboratory automation device (10) in such a way, that a liquid level in the pipette (14) solely rises in a first step and solely lowers in a second step, such that an interior surface of the pipette (14) is wetted with liquid solely one time; and during aspirating and dispensing air and liquid (22), measuring a pressure curve (40) in the pipette (14) and determining the physical parameters from the pressure curve (40), the physical parameters comprising at least one of a surface tension, a wetting angle and a viscosity.

15. 发明公开

EP4386354A1 DETERMINING PHYSICAL PARAMETERS OF A LIQUID WITH SIMULATION 审中-公开
公开(公告)号：EP4386354A1
公开(公告)日：2024-06-19
申请号：EP22213600.4
申请日：2022-12-14
申请人： Tecan Trading AG
发明人： KELLER, Michael , GEIGES, Thomas , VILAJ, Volfgang
IPC分类号： G01N11/08 , G01N13/02 , G01N35/10
CPC分类号： G01N35/1016 , G01N2035/106220130101 , G01N2035/10320130101 , G01N13/02 , G01N2013/020820130101 , G01N11/08 , G01N2013/024120130101 , G01N2013/026620130101
摘要： A method for determining physical parameters of an unknown liquid (22) to be aspirated and/or dispensed by a laboratory automation device (10) comprises: determining physical parameters of the pipette (14), the physical parameters including geometric parameters of the pipette (14), which at least include a tip radius of an orifice of the pipette (15); aspirating and/or dispensing the unknown liquid (22) with a pipette (14) of the laboratory automation device and measuring a measured pressure curve (40) in the pipette (14) during aspirating and/or dispensing; determining the physical parameters of the unknown liquid (22) by minimizing an objective function depending on a difference (44) between a simulated pressure curve and the measured pressure curve, wherein the simulated pressure curve (42) simulates a pressure in the pipette (14) during aspirating and/or dispensing and is calculated based on a physical model of the laboratory automation device (10) including the physical parameters of the pipette (14), wherein the physical parameters of the unknown liquid (22) are varied to minimize the objective function.

18. 发明授权

EP3953038B1 ASSAY CARTRIDGE AND SUPPORT HOUSING 有权
公开(公告)号：EP3953038B1
公开(公告)日：2024-06-05
申请号：EP20721683.9
申请日：2020-04-09
IPC分类号： B01L3/00 , B01L9/00 , G01N35/10
CPC分类号： B01L2200/0420130101 , B01L3/527 , B01L9/523 , B01L2200/02520130101 , B01L2300/082920130101 , B01L3/5085 , G01N35/1002

19. 发明公开

EP4370893A1 SYSTEMS AND METHODS FOR HANDLING AND ANALYZING SAMPLES 审中-实审
公开(公告)号：EP4370893A1
公开(公告)日：2024-05-22
申请号：EP22748453.2
申请日：2022-07-14
申请人： DH Technologies Development Pte. Ltd.
发明人： COVEY, Thomas R. , LIU, Chang
IPC分类号： G01N1/14 , B05B17/06 , G01N35/10
CPC分类号： B26D1/00 , G01N30/72 , B01L3/0268 , G01N2035/103420130101 , H01J49/0431 , G01N2030/883120130101 , G01N30/16 , B05B17/0615 , B05B5/03 , B05B5/16 , B01L2300/082920130101 , B01L2400/043920130101

20. 发明公开

EP4370882A1 REAL-TIME SHORT-SAMPLE ASPIRATION FAULT DETECTION 审中-实审
公开(公告)号：EP4370882A1
公开(公告)日：2024-05-22
申请号：EP22843029.4
申请日：2022-07-12
申请人： Siemens Healthcare Diagnostics, Inc.
发明人： RAMAKRISHNAN, Narayanan
IPC分类号： G01F22/02 , G01N35/10
CPC分类号： G01F22/02 , G06N20/00 , G01N2035/101820130101 , G01N35/1016

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