专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

121. 发明公开

EP1289440A4 SELECTIVE PHOTOCOAGULATION 有权
标题翻译：选择性激光光凝
公开(公告)号：EP1289440A4
公开(公告)日：2005-07-27
申请号：EP01941803
申请日：2001-06-01
申请人： GEN HOSPITAL CORP
发明人： LIN CHARLES P
IPC分类号： A61B17/00 , A61B18/00 , A61B18/20 , A61F9/008
CPC分类号： A61B18/20 , A61B2017/00057 , A61B2018/00636 , A61B2018/00642 , A61F9/008 , A61F9/00821 , A61F2009/00844 , A61F2009/00855 , A61F2009/00863 , A61F2009/00897
摘要： Selective photocoagulation of particular cells, tissue or portion of tissue can be aided by monitoring microcavitation within the material exposed to electromagnetic radiation (12). The information gained by the detection of microcavitation events can be used to modulate the intensity of the radiation (12) to prevent significant thermal energy transmission and mechanical damage to cells, tissues or portions of tissues which are not directly exposed, but prone to thermal damage by such energy transmission. Detection of microcavitation also serves as a valuable therapeutic endpoint. The methods of the invention are applicable to laser eye surgery, since the target cells of several therapeutic photocoagulation methods, the retinal pigment epithelial (RPE) cells are proximate to photoreceptor cells. The inventive methods can help prevent the formation of blind spots that can be associated with laser eye surgery. Other fields of laser surgery can also be readily adapted to the methods described herein.

122. 发明公开

EP1507487A1 VARIABLE REPETITION RATE FIRING SCHEME FOR REFRACTIVE LASER SYSTEMS 有权转让
标题翻译： FEUERUNGSSCHEMA可变重复率激光屈光系统
公开(公告)号：EP1507487A1
公开(公告)日：2005-02-23
申请号：EP03756346.7
申请日：2003-05-30
申请人： Visx, Incorporated
发明人： WONG, Jonathan
IPC分类号： A61B18/18
CPC分类号： A61F9/008 , A61B34/10 , A61F9/00806 , A61F9/00817 , A61F2009/00844 , A61F2009/00846 , A61F2009/00848 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882
摘要： Systems (10) and methods apply pulsed laser energy to an eye with a pulsed laser system. The laser system (10) includes a pulsed laser (12), a laser beam delivery system (16) and at least one processor (22). The laser (12) makes a beam (14) of an ablative light energy. A dimension across the laser beam (14) varies during a treatment of the eye (E). A firing rate of the laser (12) varies as the dimension across the beam (14) varies during the treatment. The dimension across the beam and the firing rate of the laser (12) can be arranged so as to maintain a power of the beam (14) applied to the eye at a substantially constant level during at least a portion of the treatment. A firing rate of the laser (12) for each pulse may be listed in a treatment table (140).

123. 发明公开

EP1175182A4 IMPROVED INTERFACE FOR LASER EYE SURGERY 有权
标题翻译：改进的界面，激光眼科手术
公开(公告)号：EP1175182A4
公开(公告)日：2003-09-17
申请号：EP00919765
申请日：2000-03-28
申请人： VISX INC
发明人： CLAPHAM TERRANCE N , COWPERTHWAITE MICHAEL , HOFER RICHARD A , SCRAMAGLIA ERIK
IPC分类号： A61B18/20 , A61F9/007 , A61F9/01 , A61N5/06 , B23K26/00
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00817 , A61F2009/00844 , A61F2009/00872
摘要： This invention is a laser surgery system (100) having a computer control system (22) coupled to a laser subsystem (13), and a patient seat (24). The control system (22) is coupled to the laser through a laser alignment system (17). The control system (22) can be coupled to the patient seat (24) through a patient alignment system (11). The control system (22) sends a nominal position signal to move the patient seat (24), laser subsystem (13), or both so that the patient's first eye is moved into substantial alignment with the laser beam axis. The control system (22) can send a second nominal signal to move the patient's second eye into substantial alignment with the laser beam axis. The control system (22) can optionally comprise both an operator display (23), and an assistant display (34). The assistant display (34) provides real time information to an assistant positioned at an assistant station adjacent the patient seat. The control system (22) can be programmed to display edit fields with different colors to provide an obvious indication of the refractive information of the eye. The control system (22) can comprise an operator input for providing a predetermined secondary ablative treatment. If it is determined that the first ablative treatment did not completely remove the epithelial layer from a target region, the operator actuates the operator input to deliver the secondary ablative treatment.

124. 发明公开

EP1210923A3 Control system for corneal laser surgery 有权
标题翻译：用于角膜激光手术控制系统
公开(公告)号：EP1210923A3
公开(公告)日：2003-08-27
申请号：EP01308220.1
申请日：2001-09-27
申请人： 20/10 Perfect Vision Optische Geraete GmbH
发明人： Bille, Josef
IPC分类号： A61F9/01 , A61F9/08 , A61B3/107
CPC分类号： A61B3/1015 , A61B2017/00017 , A61F9/00806 , A61F2009/00844 , A61F2009/00848 , A61F2009/00855 , A61F2009/00872 , A61F2009/0088
摘要： The present invention provides a closed-loop control system for superficial photoablation of tissue from an exposed stromal surface of an eye wherein the exposed surface introduces mechanically induced optical aberrations, said system comprising a source for generating an incising laser beam for photoablation of tissue from the exposed surface, a source for generating a diagnostic laser beam, a deformable mirror for directing said diagnostic laser beam through the exposed stromal surface to a focal spot on the retina of the eye, a detector for using light from said diagnostic beam reflected from the retina through the exposed stromal surface to generate an induced wavefront having characteristics of the mechanically induced optical aberrations, together with a distorted wavefront having actual real-time characteristics of the cornea, a compensator for altering a predetermined desired wavefront by incorporating said induced wavefront therewith to create a rectified wavefront, a comparator for comparing said rectified wavefront with said distorted wavefront to create an error signal, a means for reconfiguring said deformable mirror in accordance with said error signal to maintain a focal spot on the retina, and a means for ceasing generation of said incising laser beam when said error signal is a null. The present invention also provides a method for preparing a system for photoablation of a mechanically exposed stromal surface of an eye comprising providing the system with a distorted wavefront that has been determined by previous diagnosis of the eye and a desired wavefront.

125. 发明公开

EP1320320A1 APPARATUS FOR DETERMINING AND ABLATING THE CORNEAL TISSUE VOLUME NECESSARY FOR PERFORMING A CORNEAL LAMELLAR GRAFTING OPERATION 有权
标题翻译： DEVICE FOR在层压处理角膜移植术确定和消融角膜组织体积
公开(公告)号：EP1320320A1
公开(公告)日：2003-06-25
申请号：EP01936806.7
申请日：2001-05-18
申请人： Ligi Tecnologie Medicali S.R.L.
发明人： D'IPPOLITO, Giuseppe
IPC分类号： A61B3/10 , A61B3/11 , A61F9/013 , A61F9/01
CPC分类号： A61B3/1005 , A61B3/11 , A61F9/00804 , A61F9/0081 , A61F9/013 , A61F2009/00844 , A61F2009/00872
摘要： An apparatus for determining and ablating the corneal tissue volume necessary for performing a corneal lamellar grafting operation, in a manner optimized for each patient, comprises a central processing unit, to which are operatively connected a corneal pachymeter, of an optical, ultrasonic and the like type, a pupillometer and a photoablative laser, of an excimer, status solid, phantosecond or the like type.

126. 发明公开

EP1301154A2 LASER FLUENCE COMPENSATION OF A CURVED SURFACE 审中-公开
标题翻译：歪表面的激光流量补偿
公开(公告)号：EP1301154A2
公开(公告)日：2003-04-16
申请号：EP01901958.7
申请日：2001-01-11
申请人： LaserSight Technologies, Inc.
发明人： KLIEWER, Michael, L. , SMITH, Michael, J.
IPC分类号： A61F9/01
CPC分类号： B23K26/073 , A61F9/00806 , A61F9/00817 , A61F2009/00844 , A61F2009/00855 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882
摘要： A laser system and techniques which compensate for laser fluence drop off or losses of irradiation as an ablating laser beam is traversed on a curved surface (10) (e.g., on corneal tissue). The disclosed ablating laser system and techniques compensated for fluence differentials from pulse-to-pulse by adjusting an appropriate parameter of a laser beam. In the preferred embodiment, the number of pulses imparted in the periphery, the size or shape of the ablating laser beam is adjusted with, e.g., a variable aperture (30) placed in the beam delivery path, by changing a magnification of relay optics (40) in the beam delivery path, or by increasing a number of ablation spots in peripheral portions of an ablation zone as compared with the number of ablation spots in a central portion of the ablation zone.

127. 发明公开

EP1279385A1 Nichtinvasive Bestimmung der Temperatur an mit Strahlung behandeltem biologischem Gewebe 有权
标题翻译：史密斯生物学家Gewebe的Nichtinvasive Bestimmung der Temperatur
公开(公告)号：EP1279385A1
公开(公告)日：2003-01-29
申请号：EP02015946.3
申请日：2002-07-17
申请人： Medizinisches Laserzentrum Lübeck GmbH
发明人： Schüle, Georg , Brinkmann, Ralf
IPC分类号： A61F9/008 , A61B5/00
CPC分类号： A61B5/01 , A61B5/0095 , A61B2017/00084 , A61B2017/00128 , A61F9/00727 , A61F9/008 , A61F9/00814 , A61F9/00821 , A61F9/009 , A61F2009/00844 , A61F2009/00863
摘要： Ein Verfahren und eine Vorrichtung zur nichtinvasiven Temperaturbestimmung an mit einer Behandlungsstrahlung, insbesondere Laserstrahlung behandeltem biologischen Gewebe, insbesondere am Augenhintergrund, bei denen während der jeweiligen Bestrahlungszeit in im wesentlichen gleichen Zeitabständen zusätzliche Strahlungspulse geringer Pulsdauer und geringer Energie auf das behandelte biologische Gewebe gerichtet werden, wobei die dabei entstehenden Gewebeexpansionen und/oder -kontraktionen durch Druckmessung oder optische Messung erfasst werden und aus den Messsignalen die absoluten Temperaturwerte bestimmt werden und gegebenenfalls die Behandlungsstrahlung in Abhängigkeit davon gesteuert wird.
摘要翻译：温度测量方法使用低能量和短持续时间的附加辐射脉冲，在激光治疗期间被引导到生物组织上，或者短期中断激光辐射，通过压力测量或光学测定组织扩张和/或收缩测量，用于评估温度或温度升高。还包括用于在激光治疗期间测量生物组织的温度的装置的独立权利要求。

128. 发明公开

EP0986335A4 METHOD AND APPARATUS FOR HIGH PRECISION VARIABLE RATE MATERIAL REMOVAL AND MODIFICATION 失效
标题翻译：方法和设备变频高精度设备拆卸和CHANGE
公开(公告)号：EP0986335A4
公开(公告)日：2002-12-04
申请号：EP98922416
申请日：1998-05-19
申请人： NEEV JOSEPH
发明人： NEEV JOSEPH
IPC分类号： A61B17/00 , A61B18/20 , A61B18/26 , B23K26/06 , B23K26/067 , B23K26/18 , G01N21/71 , A61B17/36
CPC分类号： B23K26/0057 , A61B18/20 , A61B18/26 , A61B2017/00061 , A61B2017/00172 , A61B2018/00636 , A61B2018/00642 , A61B2018/00666 , A61C1/0046 , A61F9/00802 , A61F9/00825 , A61F2009/00844 , A61F2009/00872 , B23K26/0096 , B23K26/032 , B23K26/0624 , B23K26/064 , B23K26/0643 , B23K26/0665 , B23K26/067 , B23K26/0676 , B23K26/18 , B23K26/40 , B23K2203/32 , B23K2203/50 , B23K2203/52 , G01N21/718
摘要： A method and apparatus is disclosed for fast precise material processing and modification which minimizes collateral damage. Utilizing optimazed, pulsed electromagnetic energy parameters from a pulsed laser system (380) leads to an interaction regime which minimizes residual energy deposition. Advantageously, removal of cumulative pulse train residual energy is further maximized through the rapid progression of the ablation front which move faster than substantial removal of residual energy to further minimize collateral thermal damage.

129. 发明公开

EP1210923A2 Control system for corneal laser surgery 有权
标题翻译： Hornhaut-Laser-Chirurgie的Steuerungssystemfürdie
公开(公告)号：EP1210923A2
公开(公告)日：2002-06-05
申请号：EP01308220.1
申请日：2001-09-27
申请人： 20/10 Perfect Vision Optische Geraete GmbH
发明人： Bille, Josef
IPC分类号： A61F9/01
CPC分类号： A61B3/1015 , A61B2017/00017 , A61F9/00806 , A61F2009/00844 , A61F2009/00848 , A61F2009/00855 , A61F2009/00872 , A61F2009/0088
摘要： The present invention provides a closed-loop control system for superficial photoablation of tissue from an exposed stromal surface of an eye wherein the exposed surface introduces mechanically induced optical aberrations, said system comprising a source for generating an incising laser beam for photoablation of tissue from the exposed surface, a source for generating a diagnostic laser beam, a deformable mirror for directing said diagnostic laser beam through the exposed stromal surface to a focal spot on the retina of the eye, a detector for using light from said diagnostic beam reflected from the retina through the exposed stromal surface to generate an induced wavefront having characteristics of the mechanically induced optical aberrations, together with a distorted wavefront having actual real-time characteristics of the cornea, a compensator for altering a predetermined desired wavefront by incorporating said induced wavefront therewith to create a rectified wavefront, a comparator for comparing said rectified wavefront with said distorted wavefront to create an error signal, a means for reconfiguring said deformable mirror in accordance with said error signal to maintain a focal spot on the retina, and a means for ceasing generation of said incising laser beam when said error signal is a null.
The present invention also provides a method for preparing a system for photoablation of a mechanically exposed stromal surface of an eye comprising providing the system with a distorted wavefront that has been determined by previous diagnosis of the eye and a desired wavefront.
摘要翻译：本发明提供了一种闭环控制系统，用于从眼睛的暴露的基质表面的组织表面光消融，其中暴露表面引入机械感应的光学像差，所述系统包括用于产生切割激光束的源，用于从暴露表面，用于产生诊断激光束的源，用于将所述诊断激光束通过暴露的基质表面引导到眼睛的视网膜上的焦斑的可变形反射镜，用于使用来自视网膜反射的所述诊断光的光的检测器通过暴露的基质表面产生具有机械感应的光学像差的特征的感应波阵面，以及具有角膜的实际实时特性的失真波阵面，用于通过将所述感应波前并入而改变预定的所需波前的补偿器，以产生一个纠正的波前，一个比较或用于将所述经整流的波前与所述畸变波阵面进行比较以产生误差信号;根据所述误差信号重新配置所述可变形反射镜以在视网膜上保持焦点的装置，以及用于停止产生所述切割激光束的装置，所述错误信号为空。本发明还提供了一种用于制备眼睛的机械暴露的基质表面的光消融的系统的方法，包括向所述系统提供由先前的眼睛诊断和期望的波前确定的失真的波前。

130. 发明公开

EP1051781A4 LASER DELIVERY SYSTEM AND METHOD WITH DIFFRACTIVE OPTIC BEAM INTEGRATION 有权
标题翻译：激光光源和方法的研究梁DIFFRAKTIVEROPTISCHER集成
公开(公告)号：EP1051781A4
公开(公告)日：2002-05-15
申请号：EP99905449
申请日：1999-01-20
申请人： VISX INC
发明人： CAUDLE GEORGE , LEMBERG VLADIMIR
IPC分类号： G02B5/02 , A61B18/20 , A61F9/01 , B23K26/06 , G02B5/18 , G02B13/00 , G02B27/09 , H01S3/00 , H01S3/225 , H01S3/08 , A61F9/00
CPC分类号： G02B27/0927 , A61B18/201 , A61F9/00804 , A61F9/00817 , A61F2009/00844 , A61F2009/00872 , B23K26/066 , G02B27/09 , G02B27/0944 , H01S3/005
摘要： A laser delivery system and method incorporate a diffractive optic beam integrator. The diffractive optic apparatus for modifying the spatial intensity distribution of an excimer laser beam (10) to generate a spatially integrated beam comprises a diffractive optic diffuser (12) and a converging lens (22). The diffractive optic diffuser (12) includes a diffractive grating pattern etched in a transparent medium for transforming the intensity profile of the excimer laser beam into a generally circular, substantially uniform spatial intensity distribution at a spatial integration plane. A variable aperture positioned about the spatial integration plane selectively passes the spatially integrated beam to an imaging lens. The imaging lens forms an image of the passed beam about a surface of a tissue to be ablated. A scanning element under computer control scans the imaged beam about the surface.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式