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1. 发明公开

EP3054907A1 LASER EYE SURGERY SYSTEM CALIBRATION 有权
标题翻译： KALIBRIERUNG EINES AUGENLASERCHIRGGYSYSTEMS
公开(公告)号：EP3054907A1
公开(公告)日：2016-08-17
申请号：EP14786765.9
申请日：2014-10-08
申请人： Optimedica Corporation
发明人： WOODLEY, Bruce , GONZALEZ, Javier
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61B3/102 , A61F9/00804 , A61F9/00827 , A61F9/0084 , A61F2009/00851 , A61F2009/00855 , A61F2009/00882 , G01B9/02091
摘要： A laser system is calibrated with a tomography system capable of measuring locations of structure within an optically transmissive material such as a tissue of an eye. Alternatively or in combination, the tomography system can be used to track the location of the eye and adjust the treatment in response to one or more of the location or an orientation of the eye. In many embodiments, in situ calibration and tracking of an optically transmissive tissue structure such as an eye can be provided. The optically transmissive material may comprise one or more optically transmissive structures of the eye, or a non-ocular optically transmissive material such as a calibration gel in a container or an optically transmissive material of a machined part.
摘要翻译：用能够测量光学透射材料（例如眼睛组织）内的结构位置的断层摄影系统对激光系统进行校准。替代地或组合地，层析摄影系统可用于跟踪眼睛的位置并且响应于眼睛的位置或取向中的一个或多个来调整治疗。在许多实施例中，可以提供诸如眼睛之类的光学透射组织结构的原位校准和跟踪。光学透射材料可以包括眼睛的一个或多个光学透射结构，或非眼睛透光材料，例如容器中的校准凝胶或加工部件的光学透射材料。

2. 发明授权

EP2328711B1 VERFAHREN UND VORRICHTUNG ZUR KALIBRIERUNG DER PULSENERGIE EINER LASEREINRICHTUNG UNTER VERWENDUNG EINER KOHÄRENZOPTISCHEN INTERFEROMETRISCHEN MESSVORRICHTUNG 有权转让
标题翻译：方法和设备进行校准激光装置的脉冲功率来进行一致性光学干涉测量装置，
公开(公告)号：EP2328711B1
公开(公告)日：2014-09-24
申请号：EP08785759.5
申请日：2008-08-29
申请人： WaveLight GmbH
发明人： RIEDEL, Peter , DONITZKY, Christof
IPC分类号： B23K26/03 , B23K26/36 , B23K26/40 , A61F9/008 , G01B9/02
CPC分类号： B23K26/03 , A61B2017/00181 , A61F9/008 , A61F9/00804 , A61F2009/00846 , A61F2009/00855 , B23K26/364 , B23K2203/42 , B23K2203/50 , G01B9/0209

3. 发明公开

EP2709576A1 SYSTEM UND VERFAHREN ZUR CHIRURGISCHEN BEHANDLUNG EINES AUGES SOWIE VERFAHREN ZUR KALIBRIERUNG EINES DERARTIGEN SYSTEMS 有权转让
标题翻译：系统和方法眼的手术治疗，和方法进行校准这种系统的
公开(公告)号：EP2709576A1
公开(公告)日：2014-03-26
申请号：EP11720390.1
申请日：2011-05-16
申请人： WaveLight GmbH
发明人： WELLHOEFER, Armin , DONITZKY, Christof
IPC分类号： A61F9/008
CPC分类号： A61F9/00802 , A61F2009/00844 , A61F2009/00855
摘要： A system (10) for surgical treatment of an eye comprises a laser arrangement (12) designed to emit light with a wavelength and repetition rate suitable for the surgical treatment of the eye. The system (10) further comprises a temperature detector (14), which is designed to detect the temperature of an object (26) to which the light from the laser arrangement (12) is to be applied.
摘要翻译：一种用于外科治疗眼睛的系统（10）包括设计成具有适用于外科手术治疗眼睛的波长和重复速率发光的激光装置（12）。该系统（10）还包括其被设计为检测对象（26），以从所述激光装置（12）的光将被施加的温度的温度检测器（14），全部。

4. 发明公开

EP2648665A1 LASEREINRICHTUNG, INSBESONDERE FÜR DIE OPHTHALMOLOGISCHE LASERCHIRURGIE 有权转让
标题翻译： LASEREINRICHTUNG，INSBESONDEREFÜRDIE OPHTHALMOLOGISCHE LASERCHIRURGIE
公开(公告)号：EP2648665A1
公开(公告)日：2013-10-16
申请号：EP10790830.3
申请日：2010-12-10
申请人： WaveLight GmbH
发明人： WOELFEL, Mathias , KITTELMANN, Olaf , THUERMER, Daniel
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00825 , A61F2009/00855 , A61F2009/00872 , A61F2009/00897
摘要： The invention relates to a laser arrangement, in particular for ophthalmological laser surgery, comprising a laser source (14) for producing laser radiation, controllable scanning components (20) for adjusting a focus position of the laser radiation, measuring components (30) for detecting information which is representative of an actual position of the radiation focus, and a control arrangement (22) controlling the laser source and the scanning components. According to the invention, the control arrangement is configured to carry out a test run of at least some of the scanning components according to a predetermined test scanning pattern when the laser source is switched off, the test scanning pattern defining at least one scanning path for the radiation focus, and the control arrangement being configured to detect the actual focus position during a scanning movement along the scanning path several times in succession without the scanning movement stopping, and to determine a rated focus position in association with each actual focus position detected. The test run can ensure that the scanning components can move to all positions within an available scanning region even if the laser arrangement has previously experienced downtime.
摘要翻译：本发明涉及一种激光装置，特别是用于眼科激光手术，包括用于产生激光辐射的激光源（14），用于调节激光辐射的焦点位置的可控扫描部件（20），测量用于检测的部件（30）表示辐射聚焦的实际位置的信息，以及控制激光源和扫描部件的控制装置（22）。根据本发明，控制装置被配置为当激光源关闭时根据预定的测试扫描图案执行至少一些扫描部件的测试运行，测试扫描模式定义至少一个扫描路径，用于所述辐射聚焦和所述控制装置被配置为在扫描移动停止期间连续扫描多次扫描移动期间检测实际聚焦位置，并且与检测到的每个实际聚焦位置相关联地确定额定聚焦位置。测试运行可以确保扫描组件可以移动到可用扫描区域内的所有位置，即使激光装置先前已经停机。

5. 发明公开

EP2621661A1 VERFAHREN ZUM PRÜFEN EINER LASEREINRICHTUNG 有权转让
标题翻译： VERFAHREN ZUMPRÜFENEINER LASEREINRICHTUNG
公开(公告)号：EP2621661A1
公开(公告)日：2013-08-07
申请号：EP10763130.1
申请日：2010-09-30
申请人： WaveLight GmbH
发明人： GORSCHBOTH, Claudia , WOELFEL, Mathias , HEIMISCH, Richard , DONITZKY, Christof , KITTELMANN, Olaf , DEISINGER, Thomas , ROBL, Gerhard , VOGLER, Klaus , STARIGK, Martin
IPC分类号： B23K26/03 , B23K26/08 , B23K26/42 , B23K26/40 , B23K26/06 , H01S3/00 , G01M11/02 , A61F9/008
CPC分类号： G01J1/4257 , A61F9/0084 , A61F2009/00855 , B23K26/705 , B23K2203/32 , B23K2203/50
摘要： The invention relates to a method for testing a laser device (10) which is designed to provide focused, pulsed laser radiation, the focus position (18) of which can be varied both in and perpendicular to the direction of propagation of the laser radiation. The laser device comprises a contact element (30) which is transparent to the laser radiation and has a bearing surface (34) on which an object to be treated is placed. In the course of the method, a test object (36) which is transparent to laser radiation in at least one treatment area is placed against the bearing surface of the contact element. Laser radiation is then directed inside the test object that rests on the bearing surface, and the focus position is moved in accordance with a predefined test pattern in order to produce permanent treatment structures in the test object.
摘要翻译：本发明涉及一种用于测试激光装置（10）的方法，其被设计成提供聚焦的脉冲激光辐射，其焦点位置（18）可以在激光辐射的传播方向上和垂直于其方向变化。激光装置包括对激光辐射透明的接触元件（30），并具有放置待处理物体的支承表面（34）。在该方法的过程中，在至少一个处理区域中对激光辐射透明的测试对象（36）抵靠接触元件的支承表面放置。然后将激光辐射引导到放置在支承表面上的测试对象内，并且根据预定的测试图案移动聚焦位置，以便在测试对象中产生永久性的处理结构。

6. 发明授权

EP2101672B8 LASER BEAM ALIGNMENT DEVICES, SYSTEMS, AND METHODS 失效转让
标题翻译：器件，系统和激光校准方法
公开(公告)号：EP2101672B8
公开(公告)日：2012-10-03
申请号：EP08713482.1
申请日：2008-01-03
申请人： AMO MANUFACTURING USA, INC.
发明人： GRAY, Michael, S.
IPC分类号： A61F9/008
CPC分类号： G01B11/272 , A61F9/00804 , A61F9/00814 , A61F9/00838 , A61F9/0084 , A61F2009/00855 , A61F2009/0087 , A61F2009/00872 , B23K26/04 , B23K26/043 , G02B27/62

7. 发明公开

EP2462907A1 System and method for determining dosimetry in ophthalmic photomedicine 有权
标题翻译：系统用于确定眼科照片医学剂量
公开(公告)号：EP2462907A1
公开(公告)日：2012-06-13
申请号：EP12158325.6
申请日：2007-11-13
申请人： Topcon Medical Laser Systems, Inc.
发明人： Palanker, Daniel , Andersen, Dan
IPC分类号： A61F9/008
CPC分类号： A61F9/00821 , A61B3/102 , A61B18/20 , A61B90/361 , A61B2018/20351 , A61F9/008 , A61F2009/00851 , A61F2009/00855 , A61F2009/00863 , A61F2009/00868 , A61F2009/00885 , A61F2009/00897 , A61N5/0622
摘要： A system and method for treating ophthalmic target tissue, including a light source for generating a beam of light, a beam delivery system that includes a scanner for generating patterns, and a controller for controlling the light source and delivery system to create a dosimetry pattern of the light beam on the ophthalmic target tissue. One or more dosage parameters of the light beam vary within the dosimetry pattern, to create varying exposures on the target tissue. A visualization device observes lesions formed on the ophthalmic target tissue by the dosimetry pattern. The controller selects dosage parameters for the treatment beam based upon the lesions resulting from the dosimetry pattern, either automatically or in response to user input, so that a desired clinical effect is achieved by selecting the character of the lesions as determined by the dosimetry pattern lesions.

8. 发明公开

EP2391260A1 MODEL EYE FOR CALIBRATING AN OPTICAL MEASUREMENT SYSTEM OR A TREATMENT LASER SYSTEM 审中-公开
标题翻译： EYE模型校准光学测量系统或激光治疗系统
公开(公告)号：EP2391260A1
公开(公告)日：2011-12-07
申请号：EP10706166.5
申请日：2010-01-26
申请人： Bausch & Lomb Incorporated
发明人： YOUSSEFI, Gerhard , LUTZENBERGER, Birgit , HOFF, Julia , POLLAND, Hans-Joachim
IPC分类号： A61B3/00 , A61B17/00 , A61F9/008
CPC分类号： A61B3/00 , A61B2017/00716 , A61B2560/0233 , A61F9/008 , A61F2009/00844 , A61F2009/00846 , A61F2009/00855 , A61F2009/00872 , G09B23/34
摘要： The invention relates to a device for calibrating or evaluating the performance of a refractive platform, which comprises a model eye and at least one reference element. According to an aspect of the invention the reference element comprises features for identifying the calibration device, when being used in an optical measurement system and/or a treatment laser system.

9. 发明授权

EP1935385B1 Performance and accuracy assessment system for refractive laser systems 有权转让
$Performance and accuracy assessment system for refractive laser systems$
标题翻译：屈光激光系统的性能和精度检测系统
公开(公告)号：EP1935385B1
公开(公告)日：2011-05-04
申请号：EP07122888.6
申请日：2007-12-11
申请人： Alcon RefractiveHorizons, Inc.
发明人： Leblanc, Richard Alan , Sensiper, Martin , Nguyen, Phuoc Khanh
IPC分类号： A61F9/01 , A61F9/008
CPC分类号： A61F9/008 , A61F9/00814 , A61F2009/00855 , A61F2009/00872

10. 发明公开

EP2210575A2 Selective photocoagulation 有权
标题翻译：选择性凝固
公开(公告)号：EP2210575A2
公开(公告)日：2010-07-28
申请号：EP10000476.1
申请日：2001-06-01
申请人： The General Hospital Corporation
发明人： Lin, Charles P.
IPC分类号： A61F9/008
CPC分类号： A61B18/20 , A61B2017/00057 , A61B2018/00636 , A61B2018/00642 , A61F9/008 , A61F9/00821 , A61F2009/00844 , A61F2009/00855 , A61F2009/00863 , A61F2009/00897
摘要： Selective photocoagulation of particular cells, tissue or portion of tissue can be aided by monitoring microcavitation within the material exposed to electromagnetic radiation (12). The information gained by the detection of microcavitation events can be used to modulate the intensity of the radiation (12) to prevent significant thermal energy transmission and mechanical damage to cells, tissues or portions of tissues which are not directly exposed, but prone to thermal damage by such energy transmission. Detection of microcavitation also serves as a valuable therapeutic endpoint. The methods of the invention are applicable to laser eye surgery, since the target cells of several therapeutic photocoagulation methods, the retinal pigment epithelial (RPE) cells are proximate to photoreceptor cells. The inventive methods can help prevent the formation of blind spots that can be associated with laser eye surgery. Other fields of laser surgery can also be readily adapted to the methods described herein.
摘要翻译：特定细胞，组织或组织部分的选择性光凝可以通过监测暴露于电磁辐射的材料中的微气蚀来辅助（12）。通过检测微蚀刻事件获得的信息可用于调制辐射强度（12），以防止对细胞，组织或组织的显着的热能传递和机械损伤，这些组织或组织部分不直接暴露，但容易发生热损伤通过这种能量传输。微腔的检测也可作为有价值的治疗终点。本发明的方法适用于激光眼科手术，因为几种治疗性光凝方法的靶细胞，视网膜色素上皮（RPE）细胞接近感光细胞。本发明的方法可以帮助防止形成与激光眼科手术有关的盲点。激光手术的其他领域也可以容易地适应于本文所述的方法。

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