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1. 发明公开

EP2210633A3 Drug delivery device with sensor system 有权
标题翻译：与传感器系统的药物输送装置
公开(公告)号：EP2210633A3
公开(公告)日：2011-06-08
申请号：EP10151234.1
申请日：2010-01-20
申请人： Palo Alto Research Center Incorporated
发明人： Uhland, Scott , Peeters, Eric , Preas, Bryan T. , Martini, Joerg
IPC分类号： A61M5/172 , A61M5/168
CPC分类号： A61M5/1723 , A61M5/16836 , A61M5/1684 , A61M2205/3303 , A61M2205/3306 , A61M2205/3317 , A61M2205/3368
摘要： A system for use with a drug delivery device includes a sensor unit and a deactivation unit operatively coupled to an output of the sensor unit and to a drug-retaining region of the drug delivery device, wherein the drug-retaining region contains a drug. The sensor unit is configured to detect a characteristic of a local environment and generate an output corresponding to a value of the detected characteristic. The deactivation unit is configured to render the drug ineffective when the output of the sensor unit satisfies a predetermined condition.

2. 发明授权

EP2514477B1 Delivery devices with collimated gas stream and particle source 有权
公开(公告)号：EP2514477B1
公开(公告)日：2020-07-29
申请号：EP12164304.3
申请日：2012-04-16
申请人： Palo Alto Research Center Incorporated
发明人： Uhland, Scott , Peeters, Eric
IPC分类号： A61M37/00 , A61M5/30 , A61D7/00 , A61K9/00 , A61K9/70

3. 发明公开

EP2506269A1 Low temperature thermistor manufacturing process 审中-公开
标题翻译：低温热敏电阻制造工艺
公开(公告)号：EP2506269A1
公开(公告)日：2012-10-03
申请号：EP12160505.9
申请日：2012-03-21
申请人： Palo Alto Research Center Incorporated
发明人： Uhland, Scott , Daniel, Jurgen H. , Whiting, Gregory
IPC分类号： H01C7/02 , H01C7/04 , H01C17/065
CPC分类号： H01C17/06506 , H01C7/02 , H01C7/023 , H01C7/026 , H01C7/04 , H01C7/043 , H01C7/044 , H01C7/047 , Y10T29/49083
摘要： A thermistor (10) has a mixture of a temperature sensitive material (16) and a conductive material, and an electrode (14,15) in electrical contact with the mixture. A method of manufacturing a thermistor includes depositing (40) conductive contacts onto a substrate, printing (44) a thermistor mixture of temperature sensitive material and a conductive material over the contact, and annealing (46) the thermistor mixture to produce a flexible thermistor on the conductive contacts.
摘要翻译：热敏电阻（10）具有温度敏感材料（16）和导电材料的混合物，以及与混合物电接触的电极（14,15）。一种制造热敏电阻的方法包括：将导电触点沉积（40）到衬底上;在触点上印刷（44）温度敏感材料和导电材料的热敏电阻混合物;以及对热敏电阻混合物进行退火（46）以产生柔性热敏电阻导电接点。

4. 发明授权

EP2210594B1 Drug deactivation system and method of deactivating a drug using the same 有权
标题翻译：活性剂去活系统和方法的活性成分的失活，从而
公开(公告)号：EP2210594B1
公开(公告)日：2015-04-29
申请号：EP10151232.5
申请日：2010-01-20
申请人： Palo Alto Research Center Incorporated
发明人： Uhland, Scott , Peeters, Eric , Torres, Francisco E. , Schmaelzle, Philipp H.
IPC分类号： A61K9/20 , A61K9/50 , A61K9/00
CPC分类号： A61K9/0002

5. 发明公开

EP2514408A1 Drug Delivery Devices and Methods with Collimated Gas Stream and Release-Activatable Tape 有权
标题翻译： Band Band Band Band Band Band Band Band Band Band Band Band Band Band Band Band Band Band Band Band Band Band Band Band
公开(公告)号：EP2514408A1
公开(公告)日：2012-10-24
申请号：EP12164295.3
申请日：2012-04-16
申请人： Palo Alto Research Center Incorporated
发明人： Uhland, Scott , Peeters, Eric
IPC分类号： A61K9/00 , A61M5/30
CPC分类号： A61K9/0021 , A61K9/0009 , A61M5/3015
摘要： Drug delivery devices and methods are provided for delivering a substance into a human or animal tissue. The device includes a gas source (18) comprising a gas or capable of selectively producing a gas. The device also includes a drug source positioned and configured to release a drug into the gas. The drug source includes a release-activatable tape (74) having the drug disposed thereon. The device also includes a first collimator (40) fluidly connected with the gas source. The first collimator, which has an inlet end and an outlet end, is adapted to form a collimated gas stream comprising the drug in the gas.
摘要翻译：提供药物递送装置和方法用于将物质递送到人或动物组织中。该装置包括气体源（18），其包括气体或能够选择性地产生气体。该装置还包括定位并构造成将药物释放到气体中的药物源。药物源包括其上设置有药物的可释放活化的带（74）。该装置还包括与气体源流体连接的第一准直器（40）。具有入口端和出口端的第一准直器适于在气体中形成包含药物的准直气流。

6. 发明公开

EP2210633A2 Drug delivery device with sensor system 有权
标题翻译：传感器系统（Arzneimittelabgabevorrichtung mit Sensorsystem）
公开(公告)号：EP2210633A2
公开(公告)日：2010-07-28
申请号：EP10151234.1
申请日：2010-01-20
申请人： Palo Alto Research Center Incorporated
发明人： Uhland, Scott , Peeters, Eric , Preas, Bryan T. , Martini, Joerg
IPC分类号： A61M5/172 , A61M5/168
CPC分类号： A61M5/1723 , A61M5/16836 , A61M5/1684 , A61M2205/3303 , A61M2205/3306 , A61M2205/3317 , A61M2205/3368
摘要： A system for use with a drug delivery device includes a sensor unit and a deactivation unit operatively coupled to an output of the sensor unit and to a drug-retaining region of the drug delivery device, wherein the drug-retaining region contains a drug. The sensor unit is configured to detect a characteristic of a local environment and generate an output corresponding to a value of the detected characteristic. The deactivation unit is configured to render the drug ineffective when the output of the sensor unit satisfies a predetermined condition.
摘要翻译：用于药物递送装置的系统包括传感器单元和可操作地耦合到传感器单元的输出和药物递送装置的药物保持区域的停用单元，其中药物保持区域包含药物。传感器单元被配置为检测局部环境的特性并产生对应于检测到的特性的值的输出。所述停用单元被配置为当所述传感器单元的输出满足预定条件时使所述药物无效。

7. 发明公开

EP2210586A1 Drug deactivation system and method of deactivating a drug using the same 有权
标题翻译： Wirkstoffdeaktivierungssystem und Verfahren zur Deaktivierung eines Wirkstoffes damit
公开(公告)号：EP2210586A1
公开(公告)日：2010-07-28
申请号：EP10151233.3
申请日：2010-01-20
申请人： Palo Alto Research Center Incorporated
发明人： Uhland, Scott , Peeters, Eric , Torres, Francisco E. , Schmaelzle, Philipp H.
IPC分类号： A61K9/00 , A61F7/00 , A61F13/00 , A61K9/70 , A61M5/00 , A61M31/00 , A61N1/00 , A61N5/00
CPC分类号： A61N7/00 , A61F7/00 , Y10S588/90
摘要： A drug deactivation system according to some embodiments includes at least one drug-retaining region of a drug delivery device and at least one energy source coupled to the at least one drug-retaining region. The at least one drug-retaining region may be configured to retain a drug. The at least one energy source may be configured to transmit energy to the drug. The drug is capable of being rendered ineffective in the presence of the transmitted energy.
摘要翻译：根据一些实施方案的药物失活系统包括药物递送装置的至少一个药物保持区域和耦合到至少一个药物保持区域的至少一个能量源。所述至少一个药物保持区域可被配置成保留药物。所述至少一个能量源可以被配置为向所述药物传输能量。该药物能够在传播能量的存在下变得无效。

8. 发明公开

EP2116987A1 Large format microfluidic digital display 审中-公开
标题翻译： Großesdigitales mikrofluidisches显示
公开(公告)号：EP2116987A1
公开(公告)日：2009-11-11
申请号：EP09159590.0
申请日：2009-05-07
申请人： Palo Alto Research Center Incorporated
发明人： Peeters, Eric , Uhland, Scott , Schmaelzle, Philipp H.
IPC分类号： G09F9/37 , G09F13/24
CPC分类号： G09F9/37 , G02B5/24 , G02B26/004 , G09F9/375 , G09F13/24
摘要： Microfluidic pixels (110) are utilized to produce large format displays (billboards) (100) that are both digitally controllable and are light weight. Each microfluidic pixel (110) includes a wall having a front (display) surface, and a microfluidic system including a reservoir disposed behind the wall, a colorant fluid, a transparent display chamber disposed in front of the wall, a conduit, and a two-way pump. In the absence of colorant fluid in display chamber, the pixel (110) has a background appearance determined by the color (e.g., white) of the front wall surface. The pump receives a digital control signal from a digital control circuit to transfer colorant fluid from the reservoir to the display chamber by way of the conduit, whereby the pixel's appearance changes to a "colored" appearance determined by the color and amount of the colorant fluid in the display chamber.
摘要翻译：微流体像素（110）用于产生数字可控且重量轻的大格式显示器（广告牌）（100）。每个微流体像素（110）包括具有前（显示器）表面的壁和包括设置在壁后面的储存器的微流体系统，着色剂流体，设置在壁前面的透明显示室，导管和两个路泵。在显示室中没有着色剂流体的情况下，像素（110）具有由前壁表面的颜色（例如白色）确定的背景外观。泵从数字控制电路接收数字控制信号，以通过导管将着色剂流体从储存器转移到显示室，由此像素的外观变为由着色剂流体的颜色和数量确定的“有色”外观在显示室。

9. 发明授权

EP2514411B1 Needleless Transdermal Drug Delivery Devices 有权
标题翻译：针经皮剂型
公开(公告)号：EP2514411B1
公开(公告)日：2015-09-09
申请号：EP12164276.3
申请日：2012-04-16
申请人： Palo Alto Research Center Incorporated
发明人： Uhland, Scott , Peeters, Eric
IPC分类号： A61K9/14 , A61M5/30
CPC分类号： A61K9/0021 , A61M5/30 , A61M5/3015

10. 发明授权

EP2210586B1 Drug deactivation system and method of deactivating a drug using the same 有权
标题翻译：药物失活系统和使用它的失活药物的方法
公开(公告)号：EP2210586B1
公开(公告)日：2015-04-29
申请号：EP10151233.3
申请日：2010-01-20
申请人： Palo Alto Research Center Incorporated
发明人： Uhland, Scott , Peeters, Eric , Torres, Francisco E. , Schmaelzle, Philipp H.
IPC分类号： A61K9/00 , A61F7/00 , A61F13/00 , A61K9/70 , A61M5/00 , A61M31/00 , A61N1/00 , A61N5/00
CPC分类号： A61N7/00 , A61F7/00 , Y10S588/90

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