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    • 6. 发明授权
    • Removal of contaminants from biological products
    • 从生物制品中去除污染物
    • US06478967B1
    • 2002-11-12
    • US09623983
    • 2000-12-20
    • Egbert Müller
    • Egbert Müller
    • B01D6114
    • A61L2/0082B01J41/04Y10T436/255
    • The invention relates to methods for separating biological contaminants (viruses, nucleic acids and/or endotoxins) from biological products, or for reducing the content of such biological contaminants in said biological products. The sample (biological product) to be purified is treated with an anion exchanger membrane. Said anion exchanger membrane is obtained by reacting a polyamide with an aminoreactive compound which is capable of polymerisation. This is followed by polymerisation with monomers which contain cationic groups or into which cationic groups can be introduced in a reaction analogous to polymerisation.
    • 本发明涉及从生物制品中分离生物污染物(病毒,核酸和/或内毒素)或减少所述生物制品中的生物污染物的含量的方法。 将待纯化的样品(生物制品)用阴离子交换膜处理。 所述阴离子交换膜是通过使聚酰胺与能够聚合的氨基反应性化合物反应得到的。 其后是与含有阳离子基团的单体聚合,或者可以在类似于聚合的反应中引入阳离子基团。