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1. 发明授权

US06193680B1 Intrathoracic cardiac compression 失效
标题翻译：胸内心脏压迫
公开(公告)号：US06193680B1
公开(公告)日：2001-02-27
申请号：US09202245
申请日：1998-12-09
申请人： William R. Parsons , Robert H. Niermeyer
发明人： William R. Parsons , Robert H. Niermeyer
IPC分类号： A61M2902
CPC分类号： A61H31/007 , A61H2201/1238 , A61M1/106 , A61M1/1068 , A61M1/1086 , A61M1/12 , A61M2210/0625 , A61M2210/105 , A61M2230/005
摘要： Trans-esophageal cardiac compression is performed during cardiopulmonary resuscitation by introducing into the esophagus a tube (12) having a distal inflatable member, such as a balloon (20). The balloon (20) is positioned in the esophagus (48) at the level of the ventricles of the heart (50). A rapidly cycling pump (16) (such as a compressible bag) is attached to the tube (12), and used to inflate and deflate the balloon (20) on the tube (12). As the balloon (20) inflates, it compresses the ventricles against the sternum (54), increases the transmural pressure across the ventricular wall, and propels blood out of the heart (50) into the aorta and pulmonary arteries. The balloon (20) is inflated and deflated at a rate of approximately 60 cycles to 80 cycles per minute to maintain perfusion of the heart, brain and other vital organs until more definitive therapy can reestablish the contractile activity of the heart. The balloon (20) can be inflated and deflated by a handheld pump (16), or by a rapidly cycling gas pump (100). A particular embodiment of the pump includes a larger volume pump that is driven by a smaller volume drive pump which cycles rapidly to force gas into and out of the balloon.
摘要翻译：通过将具有远端可膨胀构件（例如球囊（20））的管（12）引入食管，在心肺复苏期间进行跨食道心脏压缩。气囊（20）位于心脏（50）的心室水平处的食道（48）中。快速循环泵（16）（例如可压缩袋）附接到管（12），并用于使管（12）上的球囊（20）膨胀和放气。当气囊（20）膨胀时，其将心室压缩到胸骨（54）上，增加横跨心室壁的透壁压，并将血液推出心脏（50）进入主动脉和肺动脉。气囊（20）以约60个循环的速率膨胀和放气，每分钟80次循环，以保持心脏，脑和其他重要器官的灌注，直到更确定的治疗可以重建心脏的收缩活性。气囊（20）可以由手持式泵（16）或快速循环气泵（100）充气和放气。泵的特定实施例包括较大体积的泵，其由较小体积的驱动泵驱动，其循环快速以迫使气体进入和离开气囊。

2. 发明授权

US06306074B1 Method and apparatus for radiation treatment of a desired area in the vascular system of a patient 有权
标题翻译：辐射治疗患者血管系统中所需区域的方法和装置
公开(公告)号：US06306074B1
公开(公告)日：2001-10-23
申请号：US09304783
申请日：1999-05-04
申请人： Ron Waksman , Thomas D. Weldon , Raphael F. Meloul , Richard A. Hillstead , Jonathan J. Rosen , George K. Bonnoitt, Jr. , David S. Halpern , Charles E. Larsen , Ian R. Crocker
发明人： Ron Waksman , Thomas D. Weldon , Raphael F. Meloul , Richard A. Hillstead , Jonathan J. Rosen , George K. Bonnoitt, Jr. , David S. Halpern , Charles E. Larsen , Ian R. Crocker
IPC分类号： A61M2902
CPC分类号： A61M37/0069 , A61M25/0029 , A61M25/1002 , A61M25/1006 , A61M2025/0037 , A61M2025/0039 , A61M2025/004 , A61N5/1002 , A61N5/1007 , A61N2005/1003 , A61N2005/1005 , A61N2005/1008 , A61N2005/1023
摘要： Apparatus and method are described for delivery of a treating element, such as a radiation source, through a catheter to a desired site in the intraluminal passageways of a patient, such as a coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. The apparatus includes an elongated flexible catheter tube having proximal and distal end portions, with a lumen extending therebetween, and a diameter sufficiently small for insertion in to a patient's intraluminal passageways. One or more treating elements, such as a capsule or pellet containing radioactive material, is positionable within the lumen and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. A method for using such apparatus, including a method for using such apparatus simultaneously with a balloon angioplasty procedure, is disclosed.
摘要翻译：描述了用于将治疗元件（例如辐射源）通过导管递送到患者（例如冠状动脉）的管腔内通道中用于抑制形成瘢痕组织的可能发生的装置和方法在球囊血管成形术后再狭窄。该装置包括细长的柔性导管，其具有近端部分和远端部分，其间具有内腔，并且其直径足够小以插入病人的管腔内通道。一个或多个处理元件，例如包含放射性物质的胶囊或丸粒，可定位在内腔内并且在液体流过内腔的力的作用下在近端部分和远端部分之间移动。公开了一种使用这种装置的方法，包括与球囊血管成形术程序同时使用这种装置的方法。

3. 发明授权

US06245076B1 Temperature activated adhesive for releasably attaching stents to balloons 失效
标题翻译：用于将支架可释放地附接到气球的温度活化粘合剂
公开(公告)号：US06245076B1
公开(公告)日：2001-06-12
申请号：US09575398
申请日：2000-05-22
申请人： John Y. Yan
发明人： John Y. Yan
IPC分类号： A61M2902
CPC分类号： A61F2/95 , A61F2/958 , A61F2002/30448 , A61F2002/9583 , A61F2220/005
摘要： A delivery catheter, with or without an inflation balloon, and coated with a heat activated adhesive to secure a stent thereon is disclosed. The adhesive has a phase transformation temperature just above the temperature of human blood, so that below the transformation temperature the adhesive is tacky, and above the transformation temperature the adhesive is non-tacky. In a stenting procedure, when the stent is mounted to the balloon catheter and the catheter is introduced into a body lumen, the adhesive is below the transformation temperature and remains tacky to hold the stent to the catheter. Once the stent-catheter assembly is positioned at the deployment site, a warm saline or dye solution is injected to heat the adhesive to above the transformation temperature. The adhesive becomes non-tacky and releases the bond between the catheter and deployed stent allowing the former to be withdrawn.
摘要翻译：公开了具有或不具有充气气囊的输送导管，并且涂覆有热激活的粘合剂以将支架固定在其上。粘合剂具有刚刚高于人血温度的相变温度，使得在转变温度以下，粘合剂是粘性的，并且高于相变温度，粘合剂是非粘性的。在支架术中，当支架安装到气囊导管并将导管引入体腔时，粘合剂低于转化温度并保持粘性以将支架保持在导管上。一旦支架 - 导管组件位于展开位置，则注入温暖的盐水或染料溶液以将粘合剂加热到高于转化温度。粘合剂变得非粘性，并且释放导管和部署的支架之间的结合，允许前者被拉出。

4. 发明授权

US06821287B1 Multi-mode vascular catheter system 失效
标题翻译：多模式血管导管系统
公开(公告)号：US06821287B1
公开(公告)日：2004-11-23
申请号：US07705295
申请日：1991-05-24
申请人： G. David Jang
发明人： G. David Jang
IPC分类号： A61M2902
CPC分类号： A61M25/104 , A61M25/0023 , A61M25/0029 , A61M25/003 , A61M25/0032 , A61M2025/0034 , A61M2025/0035 , A61M2025/0063 , A61M2025/0183
摘要： An intravascular catheter, comprising a catheter shaft having a proximal end and a distal end, and a guidewire lumen extending through the shaft for receiving a steerable guidewire, wherein the guidewire lumen has a proximal opening at the proximal end of the shaft for insertion of a guidewire into the lumen, and a side port for insertion of a guidewire into the lumen through the side of the catheter shaft, the side port located distally of the proximal opening and inside the patient during use, the side port being adapted to direct guidewire to extend through the side port distally into the guidewire lumen while preventing a guidewire from extending through the side port proximally into the guidewire lumen. Also disclosed are methods for using the catheter.
摘要翻译：一种血管内导管，包括具有近端和远端的导管轴，以及延伸穿过所述轴以用于接收可转向导丝的导丝内腔，其中所述导丝腔具有在所述轴的近端处的近端开口，用于插入导丝进入内腔，以及用于通过导管轴的侧面将导丝插入内腔的侧面端口，在使用期间侧向端口位于近端开口的远侧和患者体内，侧端口适于将导丝引导至通过侧端口延伸穿过导丝管腔，同时防止导丝线通过侧端口向近端延伸进入导丝管腔。还公开了使用导管的方法。

5. 发明授权

US06579301B1 Intragastric balloon device adapted to be repeatedly varied in volume without external assistance 失效
标题翻译：内置气囊装置适于在没有外部援助的情况下重复变化
公开(公告)号：US06579301B1
公开(公告)日：2003-06-17
申请号：US09716008
申请日：2000-11-17
申请人： Thomas O. Bales , Kevin W. Smith
发明人： Thomas O. Bales , Kevin W. Smith
IPC分类号： A61M2902
CPC分类号： A61F5/003 , A61F5/004
摘要： An intragastric balloon device includes a flexible bladder, a relatively rigid reservoir coupled to the bladder and adapted to hold a bladder inflation fluid, and an inflation/deflation system adapted to move or permit movement of the fluid from the reservoir and into the bladder. The intragastric balloon device is sized such that it may be positioned, in its entirety, into the stomach cavity. Various systems may be used to move or permit movement of the fluid. A control system is provided to automatically activate the inflation/deflation system. The automatic activation may be activated by a combination of one or more of a timer, the temperature of the stomach, the pressure in the stomach, the mechanical stress in the stomach, or another sensed condition, at which the control system is programmed or otherwise configured to activate.
摘要翻译：胃内气囊装置包括柔性膀胱，耦合到膀胱并适于保持膀胱膨胀流体的相对刚性的储存器，以及适于移动或允许流体从储存器移动到囊中的充气/放气系统。胃内气囊装置的尺寸使得其可以整体地定位到胃腔中。可以使用各种系统来移动或允许流体的移动。提供一种控制系统来自动启动充气/通风系统。自动激活可以通过定时器，胃的温度，胃中的压力，胃中的机械应力或另一感测条件中的一个或多个的组合来激活，控制系统被编程或以其他方式配置为激活。

6. 发明授权

US06547804B2 Selectively permeable highly distensible occlusion balloon 有权
标题翻译：选择性高透气性高密度闭塞气囊
公开(公告)号：US06547804B2
公开(公告)日：2003-04-15
申请号：US09748972
申请日：2000-12-27
申请人： Stephen Christopher Porter , Thomas Yung-Hui Chien , Huey Quoc Chan
发明人： Stephen Christopher Porter , Thomas Yung-Hui Chien , Huey Quoc Chan
IPC分类号： A61M2902
CPC分类号： A61B17/12186 , A61B17/12022 , A61B17/12113 , A61B17/12136 , A61B17/1219 , A61M2025/1054
摘要： A process and apparatus for occluding a vascular site. A catheter having a highly distensible occlusion balloon detachably mounted at a distal end thereof is provided to the vascular site and at least partially filled with an aqueous balloon inflation fluid which allows the balloon placement to be imaged. The balloon is porous to the aqueous inflation fluid and the inflation fluid is gradually displaced through the balloon pores by a liquid filling composition which is solidifiable on contact with the aqueous inflation fluid to produce a mass to which the balloon is nonporous. The filing composition is injected to bring the balloon wall into contact with the vessel wall at the vascular site. The balloon is detached from the catheter after the filling composition has at least substantially solidified and the catheter removed from the body.
摘要翻译：用于闭塞血管部位的方法和装置。具有可分离地安装在其远端处的高度可扩张的闭塞球囊的导管被提供到血管部位，并且至少部分地填充有允许气囊放置成像的水性球囊充气流体。气囊对水性充气流体是多孔的，并且膨胀流体通过液体填充组合物逐渐移位通过球囊孔隙，该液体填充组合物在与水性膨胀流体接触时可固化，以产生气球无孔的质量。注射该组合物以使球囊壁与血管部位处的血管壁接触。在填充组合物至少基本上固化并且导管从身体移除之后，气囊与导管分离。

7. 发明授权

US06364894B1 Method of making an angioplasty balloon catheter 有权
标题翻译：制造血管成形术球囊导管的方法
公开(公告)号：US06364894B1
公开(公告)日：2002-04-02
申请号：US09592499
申请日：2000-06-12
申请人： Stephen R. Healy , Jason White
发明人： Stephen R. Healy , Jason White
IPC分类号： A61M2902
CPC分类号： A61M25/1027 , A61M2025/0006 , A61M2025/1079 , A61M2025/1093
摘要： A balloon catheter for medical treatment of a patient has a proximal hub, flexible catheter shaft, a balloon, and an improved tip design. The catheter defines a guidewire lumen defined by a tubular inner body extending from a distal guidewire port to a proximal port located at a position proximal from the balloon. The guidewire lumen preferably has a constant cross-sectional area from the distal guidewire port to the proximal end of the balloon. At least one marker band is affixed to the inner body at a location within the balloon. A distal leg of the balloon is affixed to the inner body and a location between the marker band and the distal end of the inner body. A portion of the inner body extending in the proximal direction from the marker band has a substantially constant inner lumen diameter. However, the inner body wall thickness tapers to a narrower tip wall thickness, extending from a location between the marker band and the balloon distal leg, to the distal end of the inner body. A distal portion of the distal leg is also preferably tapered.
摘要翻译：用于医疗治疗患者的气囊导管具有近端毂，柔性导管轴，气囊和改进的尖端设计。导管限定由管状内体限定的导丝内腔，管状内主体从远端导丝端口延伸到位于靠近气囊的位置的近端口。导丝管腔优选地具有从远端导丝端口到气囊近端的恒定的横截面面积。至少一个标记带在气球内的一个位置固定到内体上。气囊的远端腿固定在内体上，位于标记带和内体的远端之间。从标记带沿近端方向延伸的内体的一部分具有基本上恒定的内腔直径。然而，内体壁厚度从较窄的尖端壁厚度逐渐变细，从标记带和气囊远端腿之间的位置延伸到内体的远端。远端腿的远侧部分也优选是锥形的。

8. 发明授权

US06270465B1 Method and apparatus for catheter exchange by guide wire-captivation 失效
标题翻译：通过引导线捕获导管交换的方法和装置
公开(公告)号：US06270465B1
公开(公告)日：2001-08-07
申请号：US07830479
申请日：1992-02-04
申请人： Peter T. Keith , Daniel O. Adams
发明人： Peter T. Keith , Daniel O. Adams
IPC分类号： A61M2902
CPC分类号： A61M25/0105 , A61M2025/0098
摘要： An apparatus for exchanging over-the-wire balloon catheters engages a guide wire within a guide catheter. In one embodiment the engagement is by an inflatable balloon in the guide catheter. Alternatively, the engagement is accomplished by a captivation wire in the guide catheter that has a collapsible loop portion through which the guide wire extends. Inflation of the balloon or closing the loop portion of the captivation wire within the guide catheter traps the guide wire and restricts its movement relative to the guide catheter. Once the guide wire position is fixed, withdrawal of a first balloon catheter and subsequent introduction of a second balloon catheter over the guide wire is possible without moving the guide wire longitudinally. Thus, the positioning of the guide wire over a stenosis to be dilated is not disturbed.
摘要翻译：用于更换线上气球导管的装置与导向导管内的导丝接合。在一个实施例中，接合是通过引导导管中的可充气气囊。或者，通过引导导管中的捕捉线实现接合，该引导导管具有导丝延伸穿过的可折叠环部分。引导导管中的气囊充气或闭合吸引线的环部分会捕获导丝并限制其相对于导向导管的运动。一旦引导线位置固定，就可以在不使导丝纵向移动的情况下取出第一气囊导管并随后将第二气囊导管引导到引导线上。因此，引导线在狭窄处的扩张定位不会受到干扰。

9. 发明授权

US06719775B2 Percutaneous endarterectomy 失效
标题翻译：经皮内膜切除术
公开(公告)号：US06719775B2
公开(公告)日：2004-04-13
申请号：US09766938
申请日：2001-01-22
申请人： Bradley Slaker , Daniel M. Lafontaine
发明人： Bradley Slaker , Daniel M. Lafontaine
IPC分类号： A61M2902
CPC分类号： A61M25/1006 , A61B17/22031 , A61B17/22032 , A61B2017/320044 , A61B2017/320048 , A61B2017/320741 , A61B2017/3435 , A61M25/0119 , A61M2025/109
摘要： Methods and devices for separating plaque from vessel walls using everting membranes. Everting tubes disposed on catheters are used in one embodiment of the invention to separate plaque from blood vessel walls. One embodiment of the invention utilizes a single everting membrane including a fixed portion, a leading edge, and an advancing portion. The everting tube can have an interior which can be pressurized to propel the everting tube distal edge distally onward, so as to separate the plaque from the vessel inner wall. One device has double everting membranes fixedly attached to a tubular member and having facing advancing membrane portions which may be proximally fixed relative to one another, but are preferably both free to travel distally. The outermost tube can be laid down over the vessel inner wall and the innermost tube laid down over the plaque, with the advancing surfaces of each everting membrane facing each other. Fluid can be supplied under pressure to fill the interior of the everting tubes and thereby distally advance the tube leading edges. The present invention may be used in conjunction with distal emboli capturing filter or distal occlusion devices.
摘要翻译：用永久膜分离血管壁的方法和装置。在本发明的一个实施方案中使用设置在导管上的Everting管将斑块与血管壁分开。本发明的一个实施例使用包括固定部分，前缘和前进部分的单个过渡膜。转管可以具有内部，其可以被加压以向远侧向前推动脱开管远侧边缘，以便从容器内壁分离斑块。一个装置具有固定连接到管状构件并且具有相对于彼此可以近端固定的面向前进的膜部分的双重过渡膜，但优选地是两个自由地向远侧行进。最外面的管可以放置在容器内壁上方，并且最内侧的管放置在斑块上，其中每个过渡膜的前进表面彼此面对。可以在压力下提供流体以填充出口管的内部，从而使管前缘向远侧前进。本发明可以与远端栓塞捕获过滤器或远端闭塞装置结合使用。

10. 发明授权

US06669711B1 Operation balloon 失效
标题翻译：操作气球
公开(公告)号：US06669711B1
公开(公告)日：2003-12-30
申请号：US09762697
申请日：2001-02-12
申请人： Kazuhiro Noda
发明人： Kazuhiro Noda
IPC分类号： A61M2902
CPC分类号： A61M25/1011 , A61B1/12 , A61B8/12 , A61B17/12104 , A61B17/12136 , A61B17/24 , A61B2017/00557 , A61B2017/22067 , A61H35/04
摘要： A surgical balloon which is provided with a plurality of balloons so that a fixing property and a shielding property are simultaneously satisfied, and prevents a liquid or a gas from flowing from one area in the body to another area thereof. The surgical balloon is further provided with a balloon fixing device, a drain for draining water from the front nostril and a tube for supplying rinsing water into the nasal cavity so that a surgical operation using an endoscope is carried out inside the nasal cavity with the nasal cavity filled with a water flow. A high-pressure balloon having a fixing property and a low-pressure balloon having a shielding property are combined, and the balloon is pulled from the periphery of the front nostril so as to be secured; thus, a large amount of water supply and water drain are carried out through the front nostril. Therefore, it is possible to carry out a nose surgical operation using an endoscope in a water flowing, a strong rinsing operation after the surgical operation and a diagnosis inside the nasal cavity using a ultrasonic wave.
摘要翻译：具有多个气囊的手术气囊，以同时满足定影性和屏蔽性，防止液体或气体从体内的一个区域流向其他区域。手术气囊还设置有气囊固定装置，用于从前鼻孔排出水的排水管和用于将冲洗水供应到鼻腔中的管，使得使用内窥镜的外科手术在鼻腔内部与鼻部空腔充满水流。将具有固定性的高压球囊和具有屏蔽性的低压球囊组合起来，从前鼻孔的周边被拉出以固定; 因此，通过前鼻孔进行大量的供水和排水。因此，可以使用内窥镜在水流中进行鼻外科手术，在外科手术后进行强烈的冲洗操作，并使用超声波在鼻腔内进行诊断。

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