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    • 9. 发明申请
    • Topical composition and application system
    • 专题组成和应用系统
    • US20040091551A1
    • 2004-05-13
    • US10294500
    • 2002-11-13
    • Al-Karim Damji
    • A61K033/32
    • A61K31/00A61K33/32A61K45/06A61K2300/00
    • A topical composition and application system for effectively and efficiently treating and/or preventing diaper dermatitis. The composition includes an amount of active medicinal ingredient, one or more non-medicinal ingredients used for enhancing the utility of the topical composition, and a carrier for application through either a spray-type applicator or impregnated upon a pre-moistened disposable towelette. The active ingredient is preferably zinc oxide ranging from 5 to 50% by weight, although any other active ingredient used for the prevention and/or treatment of diaper dermatitis may be used. The non-medicinal agent used may include any of the following: dimethicone, lanolin, mineral oil, petrolatum, antimicrobial agents, urea, calcium undecylenate, talc, starch, calcium carbonate, cod liver oil, Aloe, vitamin A, vitamin D, vitamin E, benzalkonium chloride, stearic acid, cetyl alcohol, skin soothing agents, emollients, moisteners, humectants, powders, pH stabilizers, chelating agents and emulsifiers.
    • 用于有效和有效地治疗和/或预防尿布性皮炎的局部组合物和应用系统。 组合物包括一定量的活性药物成分,用于增强局部组合物的用途的一种或多种非药物成分,以及通过喷雾式施用器施用或浸渍在预先润湿的一次性毛巾上的载体。 尽管可以使用用于预防和/或治疗尿布性皮炎的任何其它活性成分,但活性成分优选为5〜50重量%的氧化锌。 所使用的非药物可以包括以下任何一种:聚二甲基硅氧烷,羊毛脂,矿物油,凡士林,抗菌剂,尿素,十一碳烯酸钙,滑石粉,淀粉,碳酸钙,鳕鱼肝油,芦荟,维生素A,维生素D,维生素 E,苯扎氯铵,硬脂酸,鲸蜡醇,皮肤舒缓剂,润肤剂,润湿剂,保湿剂,粉剂,pH稳定剂,螯合剂和乳化剂。