会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 9. 发明申请
    • Method and system for desorption atmospheric pressure chemical ionization
    • 解吸大气压化学电离方法与系统
    • US20090309020A1
    • 2009-12-17
    • US12481501
    • 2009-06-09
    • Robert G. CooksBogdan GologanZoltan TakatsJustin M. WisemanIsmael Cotte-Rodriguez
    • Robert G. CooksBogdan GologanZoltan TakatsJustin M. WisemanIsmael Cotte-Rodriguez
    • H01J49/26H01J27/00H01J49/04
    • H01J49/14
    • A desorption atmospheric pressure chemical ionization (DAPCI) system delivers a primary ion beam composed of an inert, high velocity gas and solvent ions to a surface to effect desorption and ionization of both volatile and non-volatile species present on surfaces. A electrode having a tapered tip is connected to a high voltage power supply. The tapered tip projects outward from a capillary carrying a high-speed flow of gas. A vapor of a solvent is mixed into the annular gas flow surrounding the needle. The gaseous solvent vapor is ionized in close proximity to the tapered tip by virtue of the high voltage applied to the electrode. The high-speed flow of gas and solvent vapor ions extending outward from the capillary is directed toward a substrate on which an analyte of interest may have been deposited. The solvent vapor ions can blanket the surface of the analyte causing a static charge build up that facilitates ion desorption and additionally can provide positive ion adducts of the analyte freed from the substrate surface that can be directed toward an atmospheric intake of a mass spectrometer or other instrument capable of studying the analyte.
    • 解吸大气压化学电离(DAPCI)系统将由惰性高速气体和溶剂离子组成的初级离子束传送到表面,以实现表面上存在的挥发性和非挥发性物质的解吸和离子化。 具有锥形尖端的电极连接到高压电源。 锥形尖端从携带高速气体流的毛细管向外突出。 将溶剂的蒸气混合到围绕针的环形气流中。 通过施加到电极的高电压,气态溶剂蒸气被离子化,紧邻锥形尖端。 从毛细管向外延伸的气体和溶剂蒸汽离子的高速流动被引导到其上可能沉积感兴趣的分析物的基底。 溶剂蒸汽离子可以覆盖分析物的表面,导致静电荷积聚,促进离子解吸,并且另外可以提供从衬底表面释放的分析物的阳离子加合物,其可以被引导到大气摄入的质谱仪或其它 能够研究分析物的仪器。