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1. 发明申请

US20130197240A1 PROCESS FOR PREPARING AMINOADAMANTYL CARBAMATE DERIVATIVES 有权
标题翻译：制备氨基甲酰胺氨基甲酸酯衍生物的方法
公开(公告)号：US20130197240A1
公开(公告)日：2013-08-01
申请号：US13816120
申请日：2011-08-08
申请人： Yutaka Nishino , Hideki Shimizu , Takayuki Tsuritani , Natsuko Suzuki , Mutsumi Takaki , Tatsuya Kobayashi , Hideaki Sakamoto
发明人： Yutaka Nishino , Hideki Shimizu , Takayuki Tsuritani , Natsuko Suzuki , Mutsumi Takaki , Tatsuya Kobayashi , Hideaki Sakamoto
IPC分类号： C07D231/14
CPC分类号： C07D231/14 , A61K31/415 , C07B2200/07 , C07C269/02 , C07C269/06 , C07C269/08 , C07C271/34 , C07C2603/74
摘要： Disclosed is a process for producing an aminoadamantane carbamate derivative which is useful as a significant intermediate of an 11βHSD-1 inhibitor.A process for producing an acid addition salt of a compound represented by the Formula (II): or a solvate of the acid addition salt, wherein R1 and R2 are each independently hydrogen, substituted or unsubstituted alkyl or the like; R3 and R4 are each independently hydrogen, substituted or unsubstituted alkyl or the like; and R5 and R6 are each independently hydrogen, halogen, carboxy, nitro, substituted or unsubstituted alkyl or the like; which comprises separating an acid addition salt of a compound represented by the Formula (II) or a solvate of the acid addition salt by adding an acid to a mixture of syn isomer and anti isomer of a compound represented by the Formula (I): wherein R1, R2, R3, R4, R5, and R6 are as defined above, in the presence of a solvent.
摘要翻译：公开了一种生产氨基金刚烷氨基甲酸酯衍生物的方法，其可用作11betaHSD-1抑制剂的重要中间体。一种由式（II）表示的化合物的酸加成盐或其酸加成盐的溶剂化物的方法，其中R1和R2各自独立地为氢，取代或未取代的烷基等; R 3和R 4各自独立地为氢，取代或未取代的烷基等; R 5和R 6各自独立地为氢，卤素，羧基，硝基，取代或未取代的烷基等; 其包括通过向由式（I）表示的化合物的顺式异构体和反式异构体的混合物中加入酸来分离由式（II）表示的化合物的酸加成盐或酸加成盐的溶剂合物：其中在溶剂的存在下，R 1，R 2，R 3，R 4，R 5和R 6如上定义。

2. 发明授权

US08901316B2 Process for preparing aminoadamantyl carbamate derivatives 有权
标题翻译：氨基甲酰胺基氨基甲酸酯衍生物的制备方法
公开(公告)号：US08901316B2
公开(公告)日：2014-12-02
申请号：US13816120
申请日：2011-08-08
申请人： Yutaka Nishino , Hideki Shimizu , Takayuki Tsuritani , Natsuko Suzuki , Mutsumi Takaki , Tatsuya Kobayashi , Hideaki Sakamoto
发明人： Yutaka Nishino , Hideki Shimizu , Takayuki Tsuritani , Natsuko Suzuki , Mutsumi Takaki , Tatsuya Kobayashi , Hideaki Sakamoto
IPC分类号： C07C269/06 , C07C269/08 , C07C271/34 , C07D231/14 , C07C269/02 , A61K31/415
CPC分类号： C07D231/14 , A61K31/415 , C07B2200/07 , C07C269/02 , C07C269/06 , C07C269/08 , C07C271/34 , C07C2603/74
摘要： Disclosed is a process for producing an aminoadamantane carbamate derivative which is useful as a significant intermediate of an 11βHSD-1 inhibitor.A process for producing an acid addition salt of a compound represented by the Formula (II): or a solvate of the acid addition salt, wherein R1 and R2 are each independently hydrogen, substituted or unsubstituted alkyl or the like; R3 and R4 are each independently hydrogen, substituted or unsubstituted alkyl or the like; and R5 and R6 are each independently hydrogen, halogen, carboxy, nitro, substituted or unsubstituted alkyl or the like; which comprises separating an acid addition salt of a compound represented by the Formula (II) or a solvate of the acid addition salt by adding an acid to a mixture of syn isomer and anti isomer of a compound represented by the Formula (I): wherein R1, R2, R3, R4, R5, and R6 are as defined above, in the presence of a solvent.
摘要翻译：公开了一种生产氨基丁基氨基甲酸酯衍生物的方法，其可用作11重量％HSD-1抑制剂的重要中间体。一种由式（II）表示的化合物的酸加成盐或其酸加成盐的溶剂化物的方法，其中R1和R2各自独立地为氢，取代或未取代的烷基等; R 3和R 4各自独立地为氢，取代或未取代的烷基等; R 5和R 6各自独立地为氢，卤素，羧基，硝基，取代或未取代的烷基等; 其包括通过向由式（I）表示的化合物的顺式异构体和反式异构体的混合物中加入酸来分离由式（II）表示的化合物的酸加成盐或酸加成盐的溶剂合物：其中在溶剂的存在下，R 1，R 2，R 3，R 4，R 5和R 6如上定义。

3. 外观设计

USD695329S1 Digital camera 有权
公开(公告)号：USD695329S1
公开(公告)日：2013-12-10
申请号：US29428069
申请日：2012-07-25
申请人： Chikara Fujita , Tatsuya Kobayashi
设计人： Chikara Fujita , Tatsuya Kobayashi

4. 发明申请

US20130237865A1 BLOOD PRESSURE MEASUREMENT DEVICE TO BE USED ON WRIST OF PATIENT 有权
标题翻译：用于患者手腕的血压测量装置
公开(公告)号：US20130237865A1
公开(公告)日：2013-09-12
申请号：US13790026
申请日：2013-03-08
申请人： Hironori Sato , Toshihiko Ogura , Tatsuya Kobayashi , Yukiya Sawanoi , Kenji Fujii
发明人： Hironori Sato , Toshihiko Ogura , Tatsuya Kobayashi , Yukiya Sawanoi , Kenji Fujii
IPC分类号： A61B5/00 , A61B5/022
CPC分类号： A61B5/6844 , A61B5/02233 , A61B5/1071 , A61B5/1072 , A61B5/6824 , A61B5/72 , A61B5/742 , A61B2562/0219
摘要： A blood pressure measurement device includes a cuff, a display, a distance sensor, an acceleration sensor, and a CPU. The display displays a positional relationship between the patient's heart and the device, which includes a flat screen. The distance sensor measures a distance between the device and the patient, and detects a subject to be measured on a line perpendicular to the flat screen of the display and measures the distance. The acceleration sensor measures an angle of inclination of the device when mounted on the patient's wrist. The CPU calculates a positional relationship between the patient's heart and the device based on the distance between the device and the subject to be measured, the angle of inclination of the device mounted on the patient's wrist, the length of the patient's forearm and upper arm, and a vertical distance between the patient's shoulder and heart.
摘要翻译：血压测量装置包括袖带，显示器，距离传感器，加速度传感器和CPU。显示器显示患者的心脏和设备之间的位置关系，其包括平面屏幕。距离传感器测量设备和患者之间的距离，并且在垂直于显示器的平面屏幕的线上检测要测量的被摄体并测量距离。当安装在患者的手腕上时，加速度传感器测量装置的倾斜角度。 CPU根据装置和待测对象之间的距离，安装在患者手腕上的装置的倾斜角度，患者前臂和上臂的长度，计算患者心脏与装置之间的位置关系，和病人的肩膀和心脏之间的垂直距离。

5. 发明授权

US08517951B2 Blood pressure information measurement device and method of calculating arterial stiffness index with the device 有权
标题翻译：血压信息测量装置及装置计算动脉硬度指数的方法
公开(公告)号：US08517951B2
公开(公告)日：2013-08-27
申请号：US13876301
申请日：2011-07-04
申请人： Kenji Fujii , Tatsuya Kobayashi , Toshihiko Ogura
发明人： Kenji Fujii , Tatsuya Kobayashi , Toshihiko Ogura
IPC分类号： A61B5/02
CPC分类号： A61B5/02007 , A61B5/021 , A61B5/02125 , A61B5/022 , A61B5/02233 , G06F19/00
摘要： A CPU of a blood pressure information measurement device calculates blood pressure from a change in internal pressure of an air bladder used to measure the blood pressure. AI (augmentation index) and Tr (traveling time to reflected wave) are calculated from a pulse wave waveform. A path difference calculation unit of the CPU stores a correction equation to correct a pulse wave propagation distance that is stored in advance, and, by substituting the calculated blood pressure value, AI and the like into the correction equation, corrects the pulse wave propagation distance stored in advance and approximates the pulse wave propagation distance stored in advance to an actual pulse wave propagation distance. A PWV (pulse wave velocity) calculation unit calculates the PWV using the corrected distance.
摘要翻译：血压信息测量装置的CPU根据用于测量血压的气囊的内压变化来计算血压。从脉波波形计算AI（增强指数）和Tr（到反射波的行进时间）。 CPU的路径差分计算单元存储用于校正预先存储的脉波传播距离的校正方程，并且通过将计算出的血压值AI等替换为校正方程，校正脉波传播距离预先存储并且预先存储的脉搏波传播距离近似于实际的脉搏波传播距离。 PWV（脉搏波速度）计算单元使用校正距离来计算PWV。

6. 发明授权

US08028567B2 AFM tweezers, method for producing AFM tweezers, and scanning probe microscope 有权
标题翻译： AFM镊子，AFM镊子的生产方法和扫描显微镜
公开(公告)号：US08028567B2
公开(公告)日：2011-10-04
申请号：US12143410
申请日：2008-06-20
申请人： Tatsuya Kobayashi , Masato Suzuki , Masatoshi Yasutake , Takeshi Umemoto
发明人： Tatsuya Kobayashi , Masato Suzuki , Masatoshi Yasutake , Takeshi Umemoto
IPC分类号： G01B5/28 , G01Q30/20 , G01Q70/10
CPC分类号： G01Q60/38 , G01Q80/00 , Y10S977/962
摘要： AFM tweezers that include a first probe, including a triangular prism member having a tip of a ridge which is usable as a probe tip in a scanning probe microscope, and a second probe, including a triangular prism member provided so as to open/close with respect to the first probe, are provided. The first probe and the second probe are juxtaposed such that a predetermined peripheral surface of the triangular prism member of the first probe and a predetermined peripheral surface of the triangular prism member of the second probe face substantially in parallel to each other, and the first probe formed of a notch that prevents interference with a sample when the sample is scanned by the tip of the ridge.
摘要翻译：包括第一探针的AFM镊子，包括具有在扫描探针显微镜中可用作探针尖端的脊的尖端的三角形棱镜构件和第二探针，所述第二探针包括三角棱镜构件，所述三角棱镜构件设置成与提供了第一个探针。第一探针和第二探针并置，使得第一探针的三角形棱镜构件的预定外周表面和第二探针的三角形棱镜构件的预定外周表面基本上彼此平行，并且第一探针形成为当样品被脊的尖端扫描时防止样品干扰的凹口。

7. 发明授权

US07676306B2 Vehicle behavior analysis system 有权
标题翻译：车辆行为分析系统
公开(公告)号：US07676306B2
公开(公告)日：2010-03-09
申请号：US11545303
申请日：2006-10-10
申请人： Noboru Kubo , Tsuyoshi Katayama , Toshihiro Arai , Tatsuya Kobayashi , Sou Kitajima , Kazuki Yamaguchi , Shigenori Ryu , Masatomo Ishikura
发明人： Noboru Kubo , Tsuyoshi Katayama , Toshihiro Arai , Tatsuya Kobayashi , Sou Kitajima , Kazuki Yamaguchi , Shigenori Ryu , Masatomo Ishikura
IPC分类号： G01M17/00 , G06F7/00 , G06F19/00
CPC分类号： G07C5/0858 , G07C5/008 , G07C5/0891
摘要： A vehicle behavior analysis system performs an analysis of vehicle operation by displaying behavior data in an organized and analyzed form. A vehicle behavior data collecting unit records information on the vehicle's driving as behavior data and an analysis unit analyzes a recorded content of the vehicle behavior data collecting unit. A recorded data unit obtaining part obtains the recorded data units recorded in a memory of the vehicle behavior data collecting unit and a displaying part displays the content concerning at least a predetermined item among the contents shown by obtained each recorded data unit in a form of a table sectioned for each recorded data units and arranged at a side of the analysis unit, and a risk degree calculated based on the content shown by each recorded data units is contained in the predetermined item displayed by the displaying part.
摘要翻译：车辆行为分析系统通过以有组织和分析的形式显示行为数据来执行车辆操作的分析。车辆行为数据收集单元将关于车辆驾驶的信息记录为行为数据，并且分析单元分析车辆行为数据收集单元的记录内容。记录数据单元获取部分获取记录在车辆行为数据收集单元的存储器中的记录数据单元，并且显示部分以所获得的每个记录数据单元所示的内容中的至少一个预定项目的内容显示为对于每个记录的数据单元分配表并且布置在分析单元的一侧，并且基于由每个记录数据单元示出的内容计算出的风险度包含在由显示部显示的预定项目中。

8. 发明申请

US20060262154A1 Image forming apparatus 有权
标题翻译：图像形成装置
公开(公告)号：US20060262154A1
公开(公告)日：2006-11-23
申请号：US11412677
申请日：2006-04-26
申请人： Akihiko Uchiyama , Tatsuya Kobayashi
发明人： Akihiko Uchiyama , Tatsuya Kobayashi
IPC分类号： B41J29/393
CPC分类号： B41J29/393
摘要： At least one exemplary embodiment is directed to an image forming apparatus which can form a stable dot pattern to be used with a digital pen. The dot pattern used by a digital pen can be formed by changing an image forming condition, which is read by the digital pen. The image forming condition can be set based on a reading of an experimental test dot pattern.
摘要翻译：至少一个示例性实施例涉及可以形成与数字笔一起使用的稳定点图案的图像形成装置。数字笔使用的点图案可以通过改变由数字笔读取的图像形成条件来形成。可以基于实验测试点图案的读数来设置图像形成条件。

9. 发明授权

US07113713B2 Image forming apparatus using an electrophotographic process 有权
标题翻译：使用电子照相方法的图像形成装置
公开(公告)号：US07113713B2
公开(公告)日：2006-09-26
申请号：US10921183
申请日：2004-08-19
申请人： Takamitsu Soda , Tatsuya Kobayashi
发明人： Takamitsu Soda , Tatsuya Kobayashi
IPC分类号： G03G15/16 , G03G15/00
CPC分类号： G03G15/168 , G03G2221/0005
摘要： An image forming apparatus includes a first image bearing member, a movable second image bearing member, a charging device and a voltage applying device. A toner image is transferred from the first image bearing member to the second image bearing member at a first transfer portion, and the toner image is transferred from the second image bearing member to a transfer material at a second transfer portion. The charging device is opposed to the second image bearing member at a downstream side of the second transfer portion and at an upstream side of the first transfer portion with respect to a moving direction of the second image bearing member. The voltage applying device switches a DC voltage from a first voltage to a second voltage which is opposite in polarity to the first voltage. The switching from the first voltage to the second voltage is executed at a predetermined number of transfers of the toner image from the second image bearing member to the transfer material, and the predetermined number varies depending on an image forming condition.
摘要翻译：图像形成装置包括第一图像承载部件，可移动第二图像承载部件，充电装置和施加电压装置。调色剂图像在第一转印部分从第一图像承载部件转印到第二图像承载部件，并且调色剂图像在第二转印部分从第二图像承载部件转印到转印材料上。充电装置在第二转印部的下游侧和第二转印部的上游侧相对于第二图像承载部件的移动方向与第二图像承载部件相对。电压施加装置将DC电压从第一电压切换到与第一电压极性相反的第二电压。从第二图像承载部件到转印材料的调色剂图像的预定次数的转印执行从第一电压到第二电压的切换，并且预定数量根据图像形成条件而变化。

10. 发明授权

US06688335B2 Liquid hammer prevention device 失效
标题翻译：液锤预防装置
公开(公告)号：US06688335B2
公开(公告)日：2004-02-10
申请号：US09897130
申请日：2001-07-03
申请人： Tatsuya Kobayashi , Eiji Suzuki
发明人： Tatsuya Kobayashi , Eiji Suzuki
IPC分类号： F16L5504
CPC分类号： F16L55/053
摘要： A liquid hammer prevention device has a casing led to a fluid channel via passage hole, an elastic cushion made of foamed material incorporated in the casing; and a diaphragm partitioning the inside of the into an area led to the fluid channel and another area incorporating the elastic cushion. The elastic cushion is “Asker C 30 and 85” according to Japanese Industrial Standard S 6050 measured by the level gauge of a durometer “Asker C,” and is 0.30-0.70 of apparent specific gravity.
摘要翻译：液锤防止装置具有通过通孔通向流体通道的壳体，由壳体内的泡沫材料构成的弹性缓冲垫; 以及将其内部分隔成导向流体通道的区域和结合弹性垫的另一区域的隔膜。弹性垫是根据日本工业标准S 6050的“Asker C 30和85”，由硬度计“Asker C”的液位计测量，并且是表观比重的0.30-0.70。

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