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1. 发明授权

US4074654A Automatic closure cleansing and coating machine 失效
标题翻译：自动关闭清洁和涂布机
公开(公告)号：US4074654A
公开(公告)日：1978-02-21
申请号：US743213
申请日：1976-11-18
申请人： Yukihide Noguchi , Takeshi Nishimura , Jotaro Kishimoto , Yoshio Nishida
发明人： Yukihide Noguchi , Takeshi Nishimura , Jotaro Kishimoto , Yoshio Nishida
IPC分类号： B08B3/02 , B08B11/02 , B05C3/10
CPC分类号： B08B11/02 , B08B3/02
摘要： An automatic closure cleansing machine has at least two rotary carriers each having a plurality of receptacles arranged in equally spaced relation to each other and also in equally spaced relation to the axis of rotation of the corresponding rotary carrier, and first and second cleansing liquid applicators being positioned adjacent the rotary carriers, respectively, for spraying a cleansing liquid under pressure towards the closure members carried by the rotary carrier by the effect of a suction force. For this purpose, the receptacles on each rotary carrier are successively communicated to a source of vacuum. One of the opposed sides of each of the closure members is cleansed during the transportation of the closure member by the first rotary carrier while the other of the opposed sides of the closure member is cleansed during the transportation of the closure member by the second rotary carrier. A silicone resin coating may be applied to the closure members after they are removed from the second rotary carrier.
摘要翻译：自动封闭清洁机具有至少两个旋转载体，每个旋转载体具有彼此等间隔布置的多个插孔，并且还具有与相应旋转载体的旋转轴线等间隔的关系，第一和第二清洗液体施用器是分别位于旋转载体附近，用于在压力下将洗涤液体通过吸力作用于由旋转载体承载的封闭构件。为此，每个旋转载体上的容器连续地传递到真空源。每个闭合构件的相对侧之一在通过第一旋转载体运送闭合构件期间被清洁，而在通过第二旋转载体运送闭合构件期间，封闭构件的另一个相对侧被清洁。封闭构件在从第二旋转载体移除之后可以施加有机硅树脂涂层。

2. 发明授权

US4662915A Powder-air separator for use in a powder filling apparatus 失效
标题翻译：用于粉末填充装置的粉末 - 空气分离器
公开(公告)号：US4662915A
公开(公告)日：1987-05-05
申请号：US753615
申请日：1985-07-09
申请人： Norio Shirai , Jotaro Kishimoto , Yukihide Noguchi , Hideomi Ishibe , Kiyoshi Nagai
发明人： Norio Shirai , Jotaro Kishimoto , Yukihide Noguchi , Hideomi Ishibe , Kiyoshi Nagai
IPC分类号： B01D46/10 , B65B1/16
CPC分类号： B01D46/10
摘要： A powder-air separator with a filter made by sintering short-cut filament-shaped particles or by sintering a mixture of short-cut filament-shaped particles and ordinary atomized round particles.
摘要翻译：具有通过烧结短切丝状颗粒或通过烧结短切丝状颗粒和普通雾化圆形颗粒的混合物制成的过滤器的粉末 - 空气分离器。

3. 发明申请

US20090209919A1 Adhesive For Injection Needle, A Method For Bonding Injection Needle, A Syringe Front-Assembly And A Syringe 有权
标题翻译：注射针用粘合剂，注射针接合方法，注射器前组件和注射器
公开(公告)号：US20090209919A1
公开(公告)日：2009-08-20
申请号：US11921574
申请日：2006-06-05
申请人： Yuusuke Sakurai , Jotaro Kishimoto , Hiroshi Yoshikawa , Masahiko Kato
发明人： Yuusuke Sakurai , Jotaro Kishimoto , Hiroshi Yoshikawa , Masahiko Kato
IPC分类号： A61M5/32 , C09J163/00 , C08G65/04 , C08K3/22
CPC分类号： A61M5/284 , A61M5/349 , A61M2005/3132 , C09J163/00
摘要： The present invention inhibits the occurrence of the foreign matters attributable to an adhesive for bonding an injection needle to a needle-base member so as to enhance the yield of a syringe when producing the same. A front-assembly (3) additionally provided at a leading end of an injection cylinder (2) comprises an injection needle (4), a needle-base member (5), a connection hub (6) and a protector cap (7). The injection needle (4) and the needle-base member (5) are fixed to each other with an epoxy adhesive (19). This adhesive (19) contains denatured aliphatic epoxy resin in the amount set to about 10 to about 25 wt % and its viscosity is set to about 20000 to about 40000 mPa·s. This adhesive (19) is heated at a temperature of at least 130 degrees C. for about 20 minutes to cure it. After the front-assembly (3) and the injection cylinder (2) have been sterilized with vapor, the connection hub (6) has a connection portion (17) external fitted and secured to the leading end of the injection cylinder (2).
摘要翻译：本发明抑制由于将注射针粘合到针基部件上的粘合剂引起的异物的发生，从而提高注射器的制造时的产量。另外设置在注射缸（2）的前端的前组件（3）包括注射针（4），针基构件（5），连接毂（6）和保护盖（7）。注射针（4）和针基部件（5）用环氧树脂粘合剂（19）彼此固定。该粘合剂（19）含有设定为约10至约25重量％的变性脂族环氧树脂，其粘度设定为约20000至约40000mPa.s. 将该粘合剂（19）在至少130℃的温度下加热约20分钟以使其固化。在前组件（3）和注射缸（2）已经用蒸汽灭菌之后，连接毂（6）具有外部装配并固定到注射缸（2）的前端的连接部分（17）。

4. 发明授权

US5716339A Prefilled syringe 失效
标题翻译：预充注射器
公开(公告)号：US5716339A
公开(公告)日：1998-02-10
申请号：US530764
申请日：1995-09-19
申请人： Nobuo Tanaka , Jotaro Kishimoto , Kotaro Wakamatsu , Takayuki Hagihara , Seiji Chtani
发明人： Nobuo Tanaka , Jotaro Kishimoto , Kotaro Wakamatsu , Takayuki Hagihara , Seiji Chtani
IPC分类号： A61M5/28 , A61M5/31 , A61M5/315 , A61M37/00 , A61M5/00
CPC分类号： A61M5/31596 , A61M5/284 , A61M5/315 , A61M5/31511 , A61M2005/3132 , A61M5/31505 , A61M5/31513
摘要： A prefilled syringe is capable of separate storage of different substances before use. It includes a tubular body having an injection needle at one end and a plunger at the other end, and a partition axially slidable in the tubular body. The partition includes a front part and a rear part independent of each other, and as a whole divides the interior space of the tubular body into a front compartment and a rear compartment in a sealing manner for storing mutually different substances. A bypass is disposed generally between the front and rear compartments to introduce the substance in the rear compartment into the front compartment when the partition is slid under pressure provided by the plunger to be adjacent to the bypass to thereby mix the substances immediately prior to injection.
摘要翻译：预充式注射器在使用前能够分离储存不同的物质。它包括管状体，其一端具有注射针，另一端具有柱塞，以及在管状体中可轴向滑动的分隔件。分隔件包括彼此独立的前部和后部，并且整体上以密封方式将管状体的内部空间分隔成前隔室和后隔间以存储彼此不同的物质。旁路通常设置在前隔室和后隔室之间，以便当隔板在由柱塞提供的压力下滑动以邻近旁路时将后部隔室中的物质引入前隔室，从而在注射之前立即混合物质。

5. 发明授权

US5817056A Prefilled syringe 失效
标题翻译：预充注射器
公开(公告)号：US5817056A
公开(公告)日：1998-10-06
申请号：US711936
申请日：1996-09-11
申请人： Nobuo Tanaka , Jotaro Kishimoto , Kotaro Wakamatsu , Takayuki Hagihara , Seiji Ohtani
发明人： Nobuo Tanaka , Jotaro Kishimoto , Kotaro Wakamatsu , Takayuki Hagihara , Seiji Ohtani
IPC分类号： A61M5/28 , A61M5/31 , A61M5/315 , A61M37/00
CPC分类号： A61M5/31596 , A61M5/284 , A61M5/315 , A61M5/31511 , A61M2005/3132 , A61M5/31505 , A61M5/31513
摘要： A prefilled syringe capable of separate storage of different substances before use. It includes a tubular body having an injection needle at one end and a plunger at the other end, and a partition slidable axially in the tubular body. The partition includes a front part and a rear part independent of each other, and as a whole dividing the interior space of the tubular body into a front compartment and a rear compartment in a sealing manner for storing mutually different substances. A bypass is disposed generally between the front and rear compartments to introduce the substance in the rear compartment into the front compartment when the partition is slid under pressure provided by the plunger to be adjacent to the bypass to thereby mix the substances immediately prior to injection.
摘要翻译：一种预充式注射器，可在使用前分离储存不同物质。它包括一个管状体，其一端具有注射针，在另一端具有一个柱塞，以及在该管状体中可轴向滑动的分隔件。分隔件包括彼此独立的前部和后部，并且整体上以密封方式将管状体的内部空间分隔成前隔室和后隔间以存储彼此不同的物质。旁路通常设置在前隔室和后隔室之间，以便当隔板在由柱塞提供的压力下滑动以邻近旁路时将后部隔室中的物质引入前隔室，从而在注射之前立即混合物质。

6. 发明授权

US5605542A Prefilled syringe 失效
标题翻译：预充注射器
公开(公告)号：US5605542A
公开(公告)日：1997-02-25
申请号：US557517
申请日：1995-11-14
申请人： Nobuo Tanaka , Jotaro Kishimoto , Kotaro Wakamatsu , Takayuki Hagihara , Seiji Ohtani
发明人： Nobuo Tanaka , Jotaro Kishimoto , Kotaro Wakamatsu , Takayuki Hagihara , Seiji Ohtani
IPC分类号： A61M5/28 , A61M5/31 , A61M5/315 , A61M37/00
CPC分类号： A61M5/31596 , A61M5/284 , A61M5/315 , A61M5/31511 , A61M2005/3132 , A61M5/31505 , A61M5/31513
摘要： A prefilled syringe is capable of separate storage of different substances before use. It includes a tubular body having an injection needle at one end and a plunger at the other end, and a partition axially slidable in the tubular body. The partition includes a front part and a rear part independent of each other, and as a whole divides the interior space of the tubular body into a front compartment and a rear compartment in a sealing manner for storing mutually different substances. A bypass is disposed generally between the front and rear compartments to introduce the substance in the rear compartment into the front compartment when the partition is slid under pressure provided by the plunger to be adjacent to the bypass to thereby mix the substances immediately prior to injection.
摘要翻译：预充式注射器在使用前能够分离储存不同的物质。它包括管状体，其一端具有注射针，另一端具有柱塞，以及在管状体中可轴向滑动的分隔件。分隔件包括彼此独立的前部和后部，并且整体上以密封方式将管状体的内部空间分隔成前隔室和后隔间以存储彼此不同的物质。旁路通常设置在前隔室和后隔室之间，以便当隔板在由柱塞提供的压力下滑动以邻近旁路时将后部隔室中的物质引入前隔室，从而在注射之前立即混合物质。

7. 发明授权

US07967796B2 Adhesive for injection needle, a method for bonding injection needle, a syringe front-assembly and a syringe 有权
标题翻译：用于注射针的粘合剂，注射针的注射方法，注射器前组件和注射器
公开(公告)号：US07967796B2
公开(公告)日：2011-06-28
申请号：US11921574
申请日：2006-06-05
申请人： Yuusuke Sakurai , Jotaro Kishimoto , Hiroshi Yoshikawa , Masahiko Kato
发明人： Yuusuke Sakurai , Jotaro Kishimoto , Hiroshi Yoshikawa , Masahiko Kato
IPC分类号： A61M5/32 , A61M5/31 , C09J163/00 , C08L63/00
CPC分类号： A61M5/284 , A61M5/349 , A61M2005/3132 , C09J163/00
摘要： The present invention inhibits the occurrence of the foreign matters attributable to an adhesive for bonding an injection needle to a needle-base member so as to enhance the yield of a syringe when producing the same. A front-assembly (3) additionally provided at a leading end of an injection cylinder (2) comprises an injection needle (4), a needle-base member (5), a connection hub (6) and a protector cap (7). The injection needle (4) and the needle-base member (5) are fixed to each other with an epoxy adhesive (19). This adhesive (19) contains denatured aliphatic epoxy resin in the amount set to about 10 to about 25 wt % and its viscosity is set to about 20000 to about 40000 mPa·s. This adhesive (19) is heated at a temperature of at least 130 degrees C. for about 20 minutes to cure it. After the front-assembly (3) and the injection cylinder (2) have been sterilized with vapor, the connection hub (6) has a connection portion (17) external fitted and secured to the leading end of the injection cylinder (2).
摘要翻译：本发明抑制由于将注射针粘合到针基部件上的粘合剂引起的异物的发生，从而提高注射器的制造时的产量。另外设置在注射缸（2）的前端的前组件（3）包括注射针（4），针基构件（5），连接毂（6）和保护盖（7）。注射针（4）和针基部件（5）用环氧树脂粘合剂（19）彼此固定。该粘合剂（19）含有设定为约10〜约25重量％的变性脂族环氧树脂，其粘度设定为约20000〜约40000mPa·s。将该粘合剂（19）在至少130℃的温度下加热约20分钟以使其固化。在前组件（3）和注射缸（2）已经用蒸汽灭菌之后，连接毂（6）具有外部装配并固定到注射缸（2）的前端的连接部分（17）。

8. 发明授权

US5038839A Filling apparatus 失效
标题翻译：灌装机
公开(公告)号：US5038839A
公开(公告)日：1991-08-13
申请号：US380599
申请日：1989-07-17
申请人： Shuji Morimoto , Haruhiko Yoshida , Masakazu Oi , Jotaro Kishimoto , Seiji Ohtani
发明人： Shuji Morimoto , Haruhiko Yoshida , Masakazu Oi , Jotaro Kishimoto , Seiji Ohtani
IPC分类号： G01G13/29 , G01G15/00
CPC分类号： G01G15/006 , G01G13/2943
摘要： A filling machine provided with a filling amount weighing apparatus which is used in a step of preparing medical supplies and so on, and continuously fills automatically powder, liquid or the like of a very small amount into a container such as vial, ampul or the like so as to weigh the filling amount, on the employment of an electronic balance to effect a weighing operation of high speed and precision so as to improve the filling amount accuracy through the reduction in dispersion in the filling amount.
摘要翻译：一种填充机，设置有用于制备医疗用品等的步骤中的填充量计量装置，并且将少量的粉末，液体等自动连续填充到小瓶，安瓿等容器中以便对使用电子天平进行称量，以进行高速精确的称重操作，从而通过减少填充量的分散来提高填充量的精度。

9. 发明授权

US5865799A Prefilled syringe 失效
标题翻译：预充注射器
公开(公告)号：US5865799A
公开(公告)日：1999-02-02
申请号：US899053
申请日：1997-07-23
申请人： Nobuo Tanaka , Jotaro Kishimoto , Kotaro Wakamatsu , Takayuki Hagihara , Seiji Ohtani
发明人： Nobuo Tanaka , Jotaro Kishimoto , Kotaro Wakamatsu , Takayuki Hagihara , Seiji Ohtani
IPC分类号： A61M5/28 , A61M5/31 , A61M5/315 , A61M37/00
CPC分类号： A61M5/31596 , A61M5/284 , A61M5/315 , A61M5/31511 , A61M2005/3132 , A61M5/31505 , A61M5/31513
摘要： A prefilled syringe capable of separate storage of different substances before use. It includes a tubular body having an injection needle at one end and a plunger at the other end, and a partition axially slidable in the tubular body. The partition includes a front part and a rear part independent of each other, and as a whole divides the interior space of the tubular body into a front compartment and a rear compartment in a sealing manner for storing mutually different substances. A bypass is disposed generally between the front and rear compartments to introduce the substance in the rear compartment into the front compartment when the partition is slid under pressure provided by the plunger to be adjacent to the bypass to thereby mix the substances immediately prior to injection.
摘要翻译：一种预充式注射器，可在使用前分离储存不同物质。它包括管状体，其一端具有注射针，另一端具有柱塞，以及在管状体中可轴向滑动的分隔件。分隔件包括彼此独立的前部和后部，并且整体上以密封方式将管状体的内部空间分隔成前隔室和后隔间以存储彼此不同的物质。旁路通常设置在前隔室和后隔室之间，以便当隔板在由柱塞提供的压力下滑动以邻近旁路时将后部隔室中的物质引入前隔室，从而在注射之前立即混合物质。

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