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1. 发明授权

US06964641B2 Implantable medical device with sleep disordered breathing monitoring 有权
公开(公告)号：US06964641B2
公开(公告)日：2005-11-15
申请号：US10746814
申请日：2003-12-24
申请人： Yong Kyun Cho , Eduardo N. Warman , Todd J. Sheldon
发明人： Yong Kyun Cho , Eduardo N. Warman , Todd J. Sheldon
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/0215 , A61B5/022 , A61B5/0245 , A61B5/0456 , A61B5/0464 , A61B5/0476 , A61B5/08 , A61B5/083 , A61B5/087 , A61B5/11 , A61B5/113 , A61B7/00 , A61N1/36 , A61N1/365
CPC分类号： A61N1/3601 , A61B5/0031 , A61B5/01 , A61B5/0205 , A61B5/0215 , A61B5/022 , A61B5/0245 , A61B5/0456 , A61B5/0464 , A61B5/0476 , A61B5/0809 , A61B5/0816 , A61B5/0833 , A61B5/0836 , A61B5/087 , A61B5/0878 , A61B5/1116 , A61B5/1118 , A61B5/1135 , A61B5/4818 , A61B7/003 , A61N1/36521 , A61N1/36557
摘要： An implantable medical device (IMD) includes a sensor for monitoring parameters indicative of sleep disordered breathing. The IMD also includes a position sensor that indicates the relative position and/or activity level of the patient. The position sensor data is used in one or more ways in conjunction with the SDB sensing. The position data is used to confirm that such sensed data is likely indicative of SDB or to select the appropriate criteria for comparison.

2. 发明授权

US08332045B2 System and method for cardiac lead switching 有权
标题翻译：心脏导联切换的系统和方法
公开(公告)号：US08332045B2
公开(公告)日：2012-12-11
申请号：US12363327
申请日：2009-01-30
申请人： John Louis Sommer , Michael William Kimmel , Yong Kyun Cho
发明人： John Louis Sommer , Michael William Kimmel , Yong Kyun Cho
IPC分类号： A61N1/00
CPC分类号： A61N1/37 , A61N1/056 , A61N1/086 , A61N1/3718
摘要： An implantable medical device (IMD) can include an implantable pulse generator (IPG), such as a cardiac pacemaker or an implantable cardioverter-defibrillator (ICD). Various portions of the IMD, such as a device body, a lead body, or a lead tip, can be provided to reduce or dissipate a current and heat induced by various external environmental factors. According to various embodiments, features can be incorporated into the lead body, the lead tip, or the IMD body to reduce the creation of an induced current, or dissipate the induced current and heat created due to an induced current in the lead.
摘要翻译：可植入医疗装置（IMD）可以包括可植入脉冲发生器（IPG），例如心脏起搏器或植入式心律转复除颤器（ICD）。可以提供IMD的各个部分，例如装置主体，引线主体或引线头，以减少或消散由各种外部环境因素引起的电流和热量。根据各种实施例，可以将特征结合到引线体，引线尖端或IMD体中，以减少感应电流的产生，或者消散由于引线中的感应电流而产生的感应电流和热量。

3. 发明申请

US20120108984A1 INTEGRATED PATIENT CARE 有权
标题翻译：一体化患者护理
公开(公告)号：US20120108984A1
公开(公告)日：2012-05-03
申请号：US12915992
申请日：2010-10-29
申请人： Tommy D. Bennett , Yong Kyun Cho , Randolph M. Biallas
发明人： Tommy D. Bennett , Yong Kyun Cho , Randolph M. Biallas
IPC分类号： G06Q50/00 , A61B5/021
CPC分类号： G06F19/3481 , A61B5/0022 , A61B5/021 , A61B5/0215 , A61B5/0537 , A61B5/11 , A61B5/4836 , A61B5/4878 , A61B5/743 , A61B5/7435 , A61N1/37247 , G06F19/00 , G06F19/3456 , G06Q50/22 , G16H40/63 , G16H50/20
摘要： A therapy regimen, e.g., a contingent medication prescription, may be created and automatically distributed to a patient via an integrated patient care system. A clinician may create therapy instructions by at least associating patient conditions with one or more therapy regimens, e.g., medication prescriptions. In some examples, the integrated patient care system may present historical condition data to the clinician to aid the clinician with creating and/or updating the therapy instructions specific to the patient. A therapy module of the integrated patient care system may use the therapy instructions to automatically select a therapy regimen from the therapy instructions based on a patient condition detected based on a sensed physiological parameter. The physiological parameter of the patient may be sensed by an implanted or external sensor. In some examples, the therapy regimen can be presented to the patient according to a predetermined schedule or in response to the detected condition.
摘要翻译：可以创建治疗方案，例如或有药物处方，并通过综合的患者护理系统自动分配给患者。临床医生可以通过至少将患者状况与一种或多种治疗方案（例如药物处方）相关联来产生治疗指导。在一些示例中，综合的患者护理系统可向临床医生呈现历史状态数据，以帮助临床医生创建和/或更新患者特有的治疗指导。综合患者护理系统的治疗模块可以使用治疗指令根据基于检测到的生理参数检测到的患者状况从治疗指令中自动选择治疗方案。患者的生理参数可以通过植入或外部传感器来感测。在一些实例中，治疗方案可以根据预定的时间表或响应于检测到的病症呈现给患者。

4. 发明授权

US06944489B2 Method and apparatus for shunting induced currents in an electrical lead 失效
标题翻译：用于在电引线中分流感应电流的方法和装置
公开(公告)号：US06944489B2
公开(公告)日：2005-09-13
申请号：US10059512
申请日：2002-01-29
申请人： Volkert A. Zeijlemaker , Ron Kalin , Gregory A. Hrdlicka , Yong Kyun Cho , James D. Reinke , Laurie D. Foerster
发明人： Volkert A. Zeijlemaker , Ron Kalin , Gregory A. Hrdlicka , Yong Kyun Cho , James D. Reinke , Laurie D. Foerster
IPC分类号： A61N20060101 , A61N1/05 , A61N1/362 , A61N1/372 , A61N1/39 , A61B5/04
CPC分类号： A61N1/056 , A61N1/086 , A61N1/3718
摘要： An electrical lead includes an elongate body having a proximal end portion and a distal end portion, a first electrode disposed adjacent and joined to the distal end portion of the elongate body. Current flow within the first electrode is limited when a predetermined condition occurs, such as the generation of an electromagnetic field having a predetermined frequency range. The medical electrical lead may further comprise one or more second electrodes disposed adjacent the first electrode and joined to the elongate body to shunt current to body tissue when the predetermined condition occurs.
摘要翻译：电引线包括具有近端部分和远端部分的细长主体，与细长主体的远端部分相邻并连接的第一电极。当预定条件发生时，例如产生具有预定频率范围的电磁场，第一电极内的电流被限制。医疗电引线还可以包括一个或多个第二电极，其邻近第一电极设置并连接到细长主体，以在发生预定条件时将电流分流到身体组织。

5. 发明授权

US08585604B2 Integrated patient care 有权
标题翻译：综合病人护理
公开(公告)号：US08585604B2
公开(公告)日：2013-11-19
申请号：US12915992
申请日：2010-10-29
申请人： Tommy D. Bennett , Yong Kyun Cho , Randolph M. Biallas
发明人： Tommy D. Bennett , Yong Kyun Cho , Randolph M. Biallas
IPC分类号： A61B5/02
CPC分类号： G06F19/3481 , A61B5/0022 , A61B5/021 , A61B5/0215 , A61B5/0537 , A61B5/11 , A61B5/4836 , A61B5/4878 , A61B5/743 , A61B5/7435 , A61N1/37247 , G06F19/00 , G06F19/3456 , G06Q50/22 , G16H40/63 , G16H50/20
摘要： A therapy regimen, e.g., a contingent medication prescription, may be created and automatically distributed to a patient via an integrated patient care system. A clinician may create therapy instructions by at least associating patient conditions with one or more therapy regimens, e.g., medication prescriptions. In some examples, the integrated patient care system may present historical condition data to the clinician to aid the clinician with creating and/or updating the therapy instructions specific to the patient. A therapy module of the integrated patient care system may use the therapy instructions to automatically select a therapy regimen from the therapy instructions based on a patient condition detected based on a sensed physiological parameter. The physiological parameter of the patient may be sensed by an implanted or external sensor. In some examples, the therapy regimen can be presented to the patient according to a predetermined schedule or in response to the detected condition.
摘要翻译：可以创建治疗方案，例如或有药物处方，并通过综合的患者护理系统自动分配给患者。临床医生可以通过至少将患者状况与一种或多种治疗方案（例如药物处方）相关联来产生治疗指导。在一些示例中，综合的患者护理系统可向临床医生呈现历史状态数据，以帮助临床医生创建和/或更新患者特有的治疗指导。综合患者护理系统的治疗模块可以使用治疗指令根据基于检测到的生理参数检测到的患者状况从治疗指令中自动选择治疗方案。患者的生理参数可以通过植入或外部传感器来感测。在一些实例中，治疗方案可以根据预定的时间表或响应于检测到的病症呈现给患者。

6. 发明授权

US07206635B2 Method and apparatus for modifying delivery of a therapy in response to onset of sleep 有权
标题翻译：响应睡眠发作改变治疗递送的方法和装置
公开(公告)号：US07206635B2
公开(公告)日：2007-04-17
申请号：US10736370
申请日：2003-12-15
申请人： Yong Kyun Cho , Donald N. Jensen , Luc R. Mongeon
发明人： Yong Kyun Cho , Donald N. Jensen , Luc R. Mongeon
IPC分类号： A61F1/365
CPC分类号： A61N1/36521 , A61N1/36542 , A61N1/3702
摘要： A method and apparatus for providing a therapy to the patient that includes a therapy component configured to provide the therapy to the patient, sensing circuitry sensing a parameter of the patient, and a microprocessor coupled to the therapy component and the sensing circuitry to determine onset of a first state of the patient in response to the sensed physiologic parameter, and to determine whether the onset of the first state is detected for a predetermined time period.
摘要翻译：一种用于向患者提供治疗的方法和装置，包括治疗组件，其被配置为向患者提供治疗，感测电路感测患者的参数，以及耦合到治疗组件和感测电路的微处理器，以确定响应于感测到的生理参数的患者的第一状态，并且确定在预定时间段内是否检测到第一状态的开始。

7. 发明授权

US07031772B2 Method and apparatus for rate responsive adjustments in an implantable medical device 有权
公开(公告)号：US07031772B2
公开(公告)日：2006-04-18
申请号：US10134560
申请日：2002-04-29
申请人： Catherine R. Condie , John D. Wahlstrand , Gerald A. Portzline , Yong Kyun Cho , John S. Brandstetter , Luc R. Mongeon
发明人： Catherine R. Condie , John D. Wahlstrand , Gerald A. Portzline , Yong Kyun Cho , John S. Brandstetter , Luc R. Mongeon
IPC分类号： A61N1/365
CPC分类号： A61N1/36542 , A61N1/36521 , G06F19/00 , G06F19/3456 , G16H40/63
摘要： A method and an apparatus for performing rate responsive control in an implantable medical device using a scaling factor. Sensor data is acquired using a sensor operatively coupled with the implantable medical device. At least one setpoint for controlling a rate of therapy is generated, the setpoint being based upon the sensor data. A scaling factor adjustment process is performed for scaling the internal sensor data to correlate the sensor data to the setpoint. The rate of therapy is adjusted based upon the scaling factor adjustment.

8. 发明授权

US06752765B1 Method and apparatus for monitoring heart rate and abnormal respiration 有权
标题翻译：用于监测心率和异常呼吸的方法和装置
公开(公告)号：US06752765B1
公开(公告)日：2004-06-22
申请号：US09715637
申请日：2000-11-17
申请人： Donald N. Jensen , Linda L. Ruetz , Catherine R. Condie , Yong Kyun Cho , Ulla Strobel , Scott Davie
发明人： Donald N. Jensen , Linda L. Ruetz , Catherine R. Condie , Yong Kyun Cho , Ulla Strobel , Scott Davie
IPC分类号： A61N1365
CPC分类号： A61N1/36521
摘要： An implantable device having enhanced capabilities for monitoring a patient's heart rate and respiration trends over extended periods of time is disclosed. The information collected by the implantable device may be stored and telemetered to an associated external device such as a device programmer for display and analysis. Heart rates are measured by measuring the time intervals between sensed depolarizations of a chamber of the patient's heart and preceding sensed depolarizations or delivered pacing pulses. Intervals may be measured in the ventricle and/or atrium of the patient's heart. According to another aspect of the invention, an implanted impedance sensor is employed to monitor minute ventilation. The heart rate and minute ventilation data is used to develop long-term trend data used for diagnostic purposes. In one embodiment of the invention, heart interval and minute ventilation measurements are taken only during defined time periods of the night and/or day when the patient is at rest. A sensor such as an activity sensor or metabolic rate sensor may be used to confirm patient inactivity.
摘要翻译：公开了一种具有增强的用于监测患者的心率和延长的时间段的呼吸趋势的能力的可植入装置。由可植入装置收集的信息可以存储和遥测到相关联的外部设备，例如用于显示和分析的设备编程器。通过测量感觉到的患者心脏的室的去极化和之前感测到的去极化或发出的起搏脉冲之间的时间间隔来测量心率。间隔可以在患者心脏的心室和/或心房中测量。根据本发明的另一方面，采用植入式阻抗传感器来监测分钟通气。心率和分钟通气数据用于开发用于诊断目的的长期趋势数据。在本发明的一个实施例中，心脏间隔和分钟通气测量仅在患者休息的夜晚和/或天的限定时间段期间进行。可以使用诸如活性传感器或代谢率传感器的传感器来确认患者不活动。

9. 发明授权

US08483833B2 Techniques for modifying breathing rate using cardiac pacing 有权
标题翻译：使用心脏起搏改善呼吸频率的技术
公开(公告)号：US08483833B2
公开(公告)日：2013-07-09
申请号：US13103861
申请日：2011-05-09
申请人： Yong Kyun Cho , Mark K. Erickson , Tommy D. Bennett
发明人： Yong Kyun Cho , Mark K. Erickson , Tommy D. Bennett
IPC分类号： A61N1/00
CPC分类号： A61N1/36114 , A61N1/056 , A61N1/3611
摘要： A method includes controlling a cardiac pacing rate of an implantable medical device to control a heart rate of a patient and detecting inhalation and exhalation of the patient. The method further includes determining that the patient is in a resting state, and, in response to determining that the patient is in the resting state, incrementally increasing the pacing rate while exhalation of the patient is detected and incrementally decreasing the pacing rate while inhalation of the patient is detected.
摘要翻译：一种方法包括控制可植入医疗装置的心脏起搏速率以控制患者的心率并检测患者的吸入和呼气。该方法还包括确定患者处于静止状态，并且响应于确定患者处于静止状态，逐渐增加起搏速率，同时检测到患者的呼气，并逐渐降低起搏速率，同时吸入检测到患者。

10. 发明授权

US08478400B2 Pressure and impedance based discrimination of hemodynamic stability 有权
标题翻译：基于压力和阻抗的区分血流动力学稳定性
公开(公告)号：US08478400B2
公开(公告)日：2013-07-02
申请号：US12108818
申请日：2008-04-24
申请人： Douglas A. Hettrick , Kevin P. Vincent , Shantanu Sarkar , Yong Kyun Cho , Todd M. Zielinski
发明人： Douglas A. Hettrick , Kevin P. Vincent , Shantanu Sarkar , Yong Kyun Cho , Todd M. Zielinski
IPC分类号： A61N1/39
CPC分类号： A61N1/36585 , A61B5/0215 , A61B5/0402 , A61B5/053 , A61N1/36521 , A61N1/36564
摘要： An implantable cardioverter defibrillator evaluates the hemodynamic stability of an arrhythmia to determine whether or not to defibrillate. The device obtains cardiac pressure and cardiac impedance data and evaluates a phase relationship between these parameters. Hemodynamically stable rhythms will result in an out of phase relationship.
摘要翻译：植入式心律转复除颤器评估心律失常的血液动力学稳定性，以确定是否除颤。该装置获得心脏压力和心脏阻抗数据，并评估这些参数之间的相位关系。血液动力学稳定的节律将导致异相关系。

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