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    • 1. 发明授权
    • Process for manipulating microscopic, dielectric particles and a device
therefor
    • 用于操作微观电介质颗粒的方法及其装置
    • US6149789A
    • 2000-11-21
    • US508079
    • 1995-07-27
    • Wolfgang BeneckeBernd WagnerGunter FuhrRolf HagedornThorsten Muller
    • Wolfgang BeneckeBernd WagnerGunter FuhrRolf HagedornThorsten Muller
    • B01F13/00B01J19/00B03C5/00B03C5/02G01N27/447G01N27/26
    • B01F13/0077B01F13/0076B01J19/0093B03C5/005B03C5/026B03C5/028B01F13/0059B01J2219/00853
    • Disclosed is a process for manipulating microscopic dielectric particles in which particles are exposed to an electric field. In disadvantaged processes the particles are exposed to inhomogeneous electric field and are polarized by them. The polarized particles are moved in the direction of higher field strength. These processes permit no reversal of the traveling direction of the particles. The particles are enriched at the electrode so that they cannot be retained in free space. In the invented process the particles are exposed to high-frequency field traveling in one or more prescribed direction, by which the particles are subject to a force which sets them in a motion that is strongly synchronous to the field. With the aid of a device for carrying out the invented process, the particles can be manipulated very flexibly. By means of linearly or circularly disposed electrodes, the particles can be moved on linear paths in any direction including through branched microstructures, they can be separated according to their dielectric properties and retained without contact. Applications are in the fields of biotechnology and molecular separation, focussing and microtransport technology.
    • 公开了一种操作微粒介质颗粒的方法,其中颗粒暴露于电场。 在不利的过程中,颗粒暴露于不均匀的电场,并被它们极化。 极化粒子沿高场强的方向移动。 这些处理不允许反转颗粒的行进方向。 颗粒在电极处富集,使得它们不能保留在自由空间中。 在本发明的方法中,颗粒暴露于在一个或多个规定方向上行进的高频场,通过该方法,颗粒受到将其设置成与场强同步的运动的力。 借助于用于实施本发明方法的装置,可以非常灵活地操纵颗粒。 通过线性或圆形设置的电极,颗粒可以在包括通过分支微结构的任何方向上在线性路径上移动,它们可以根据其介电性质分离并保持而不接触。 应用领域包括生物技术和分子分离,聚焦和微传输技术。
    • 5. 发明授权
    • Cryopreserving and cryogenically processing biological objects
    • 冷冻保存和低温处理生物体
    • US5925511A
    • 1999-07-20
    • US836092
    • 1997-08-29
    • Gunter FuhrJan HornungRolf HagedornTorsten MullerSteffen HowitzBernd WagnerUlrich Hofmann
    • Gunter FuhrJan HornungRolf HagedornTorsten MullerSteffen HowitzBernd WagnerUlrich Hofmann
    • A01N1/00A01N1/02A01N3/00
    • A01N1/02A01N1/0257A01N1/0278A01N1/0294
    • For the fixated cryopreservation of single living biological objects or s objects compiled in a given number (for example cells) a cryogenically cooled substrate (13) is jetted therewith in a enveloping solution in microdroplet form (12) from a storage vessel, for example by means of a microdroplet jetting device (11). The substrate is temperature-controlled via a coolant (15), the surface to be jetted being located in a gas atmosphere or in vacuum (14). The substrate surface is maintained at a temperature T1 resulting in freezing of the impinging microdroplet, the substrate surface being possibly supportingly microstructured and comprising sensing elements. By controlled movement of either the substrate or the microdroplet jetting device the microdroplets can be applied singly and in patterns in arrays freely selectable or predetermined by the structuring of the substrate. The substrate with the applied microdroplets and the cells frozen therein are stored and/or processed by a processing means (17) ablating the material or applying said material at temperatures T2 of down to -273.degree. C. In the cryogenic condition manipulations such as removal by mechanical ablation or addition of solutions or substances to the surface of the substrate can be undertaken. During thawing the substrate surface is brought to a temperature T1 above the freezing point of the enveloping solution and the microdroplet array thawed in a predefined manner.
    • PCT No.PCT / DE95 / 01490 Sec。 371日期1997年8月29日 102(e)日期1997年8月29日PCT提交1995年10月26日PCT公布。 第WO96 / 13159号公报 日期1996年5月9日对于以一定数量(例如细胞)编制的单一活生物体或此类物体的固定式低温保存,将低温冷却的基底(13)以微滴形式(12)的包封溶液从储存容器 ,例如通过微滴喷射装置(11)。 衬底通过冷却剂(15)进行温度控制,待喷射的表面位于气体气氛或真空中(14)。 衬底表面保持在温度T1,导致撞击微滴的冻结,衬底表面可能被支撑地微结构化并且包括感测元件。 通过基板或微滴喷射装置的受控运动,微滴可以单独施加,并且可以通过基板的结构自由选择或预定的阵列中的图案施加。 具有施加的微滴和在其中冷冻的细胞的基质通过处理装置(17)储存和/或处理,该处理装置(17)在低至-273℃的温度T2下烧蚀材料或施加所述材料。在低温条件下操作,例如去除 可以通过机械消融或将溶液或物质添加到基材表面进行。 在解冻期间,将衬底表面的温度T1提高到高于包络溶液的凝固点并且微滴阵列以预定方式解冻。
    • 6. 发明授权
    • Shaping of microparticles in electric-field cages
    • 电场笼中微粒的形成
    • US5948328A
    • 1999-09-07
    • US700395
    • 1996-08-23
    • Stefan FiedlerAndreas VoigtThomas SchnelleGuenter FuhrTorsten MuellerRolf HagedornJan HornungHenning GlasserBernd Wagner
    • Stefan FiedlerAndreas VoigtThomas SchnelleGuenter FuhrTorsten MuellerRolf HagedornJan HornungHenning GlasserBernd Wagner
    • B01J2/00B01J13/02B01J19/08
    • B01J13/02B01J19/087B01J2/00
    • In the method proposed, microparticles suspended in a liquid or droplets suspended in a liquid with which they are immiscible are shaped by high-frequency electric fields in a three-dimensional electrode array of a size in the micrometer or submicrometer range and subsequently consolidated by prior art chemical bonding procedures or by physical methods. The disposition, geometry and control of the electrodes determine the shape of the particles. The particles themselves must have a conductivity and/or relative dielectric constant lower than the solution surrounding them. For some, this can be achieved only at certain frequencies in the kHz and MHz band which are determined by the passive electrical properties of the particles and the surrounding solution. The particles or droplets are repelled by the electrodes so that they are shaped in the free solution without making contact with any surface and can then be consolidated. This makes it possible to shape micrometer and submicrometer size particles of the kind required in chromatography, affinity biochemistry and medicine, as well as for filter systems.
    • PCT No.PCT / DE95 / 00237 Sec。 371日期:1996年8月23日 102(e)日期1996年8月23日PCT提交1995年2月23日PCT公布。 WO95 / 23020 PCT公开号 日期1995年8月31日在所提出的方法中,悬浮在液体中的微粒悬浮在与其不混溶的液体中的微滴通过在微米或亚微米范围内的尺寸的三维电极阵列中的高频电场 并随后通过现有技术的化学键合方法或通过物理方法进行固结。 电极的布置,几何形状和控制决定了颗粒的形状。 颗粒本身必须具有低于围绕它们的溶液的导电性和/或相对介电常数。 对于一些,这只能在通过颗粒和周围溶液的被动电特性确定的kHz和MHz频带的某些频率下实现。 颗粒或液滴被电极排斥,使得它们在游离溶液中成形,而不与任何表面接触,然后可以被固结。 这使得可以形成色谱,亲和力生物化学和药物所需类型的微米和亚微米尺寸的颗粒,以及过滤系统。
    • 7. 发明授权
    • Assembly having variable capacitance
    • 组件具有可变电容
    • US06700299B2
    • 2004-03-02
    • US10343975
    • 2003-03-31
    • Hans-Joachim QuenzerBernd WagnerBeatrice Wenk
    • Hans-Joachim QuenzerBernd WagnerBeatrice Wenk
    • H03H970
    • H01G5/16H01G5/14H01G5/18
    • The present invention relates to an assembly of variable capacitance as well as to a method of operating the assembly. In the assembly, a variable capacitor is formed by a variable coverage or a variable distance of at least one first (4) and one second electrically conductive region (5). The first electrically conductive region (4) is configured on or in a substrate (1) and said second electrically conductive region (5) is configured on or in an actuator element (3) of a first micro-mechanical actuator (2). The actuator (2) is disposed on the substrate (1) in such a way that it can perform a movement of the actuator element (3) with the second region (5) along a surface of the substrate (1) at different positions relative to the first region (4), at which positions the second region (5) overlaps the first region (4) at least partly. Moreover, holding means (6, 10, 11) are provided which are capable of pulling or pushing the actuator element (3) in the different positions towards the substrate (1) or a mechanical stop (13) on the substrate (1), and of holding it in these positions. The inventive assembly serves to implement a variable capacitance that presents a high stability in resistance to outside influences according to its respective setting.
    • 本发明涉及可变电容的组件以及操作组件的方法。 在组件中,可变电容器由至少一个第一(4)和一个第二导电区域(5)的可变覆盖或可变距离形成。 第一导电区域(4)构造在衬底(1)上或衬底(1)中,并且所述第二导电区域(5)构造在第一微机械致动器(2)的致动器元件(3)上或其中。 致动器(2)以这样的方式设置在基板(1)上,使得其可以在相对于基板(1)的不同位置处沿着基板(1)的表面执行致动器元件(3)与第二区域(5)的移动 到所述第一区域(4),所述第二区域(5)至少部分地与所述第一区域(4)重叠的位置。 此外,提供保持装置(6,10,11),其能够将致动器元件(3)在朝向基板(1)的不同位置或基板(1)上的机械止动件(13)上拉或推动, 并将其保持在这些位置。本发明的组件用于实现根据其各自设置呈现出对外部影响的高稳定性的可变电容。
    • 8. 发明授权
    • Frangible portion of one-time-use camera must be broken to open camera,
which leaves hold to discourage unauthorized recycling
    • 一次性使用相机的易碎部分必须破碎才能打开相机,这样可以防止未经授权的回收
    • US5905915A
    • 1999-05-18
    • US861876
    • 1997-05-22
    • Bernd Wagner
    • Bernd Wagner
    • G03B17/02
    • G03B17/02G03B2219/045
    • A one-time-use camera comprising a main body part, and a cover part connected to the main body part which at least partially covers the main body part, is characterized in that a continuous line of weakness circumscribes a predetermined portion of the main body part or cover part to permit the predetermined portion to be broken away from the main body part or cover part along the continuous line of weakness and leave a hole in the main body part or cover part in the place of the predetermined portion, and the cover part is connected to the main body part at the predetermined portion to cause the predetermined portion to be broken away from the main body part or cover part when the main body part and the cover part are forcibly pulled apart.
    • 一种一次性照相机,包括主体部分和连接到至少部分地覆盖主体部分的主体部分的盖部分,其特征在于,连续的弱线包围主体的预定部分 部分或覆盖部分,以允许预定部分沿着连续的虚线从主体部分或盖部分分离,并且在主体部分或盖部分中在预定部分的位置处留下孔,并且盖 部分在预定部分处连接到主体部分,以在主体部分和盖部分被强制拉开时使预定部分从主体部分或盖部分分离。
    • 9. 发明授权
    • Torsional vibration damper
    • 扭转振动阻尼器
    • US5449322A
    • 1995-09-12
    • US969310
    • 1993-02-16
    • Bernd Wagner
    • Bernd Wagner
    • F16F15/14F16F15/12F16F15/30
    • F16F15/1442F16H2055/366
    • Torsional vibration dampers for piston engines, particularly for motor vehicle engines, are mounted on the crankshaft of the engine in a torsionally resistant manner. The hub (2) bears a first flyring (3) which concentrically surrounds the hub and is connected to the outer surface of the hub (2) via a rubber spring device (5) acting in the peripheral direction. Furthermore, a second flyring is provided which is secured to the hub (2) via a rubber spring device (8), again acting in the peripheral direction. To allow a torsional vibration damper of this kind to damp all vibrations generated by the engine using simple means, the rubber spring device (5) bearing the first flyring (3) is rigid while the rubber spring device (8) of the second flyring (4), which is located radially outside the first flyring (3), is flexible. The outer flyring (4), which has a greater mass moment of inertia than the inner flyring (3), can be connected in parallel or in series with the inner flyring (3) via its rubber spring device (8).
    • PCT No.PCT / DE91 / 00635 Sec。 371日期:1993年2月16日 102(e)日期1993年2月16日PCT 1991年8月16日PCT PCT。 出版物WO92 / 03669 日期:1992年3月5日。用于活塞式发动机,特别是汽车发动机的减震器以扭转方式安装在发动机曲轴上。 毂(2)具有同心地围绕轮毂的第一飞轮(3),并通过沿周向方向作用的橡胶弹簧装置(5)连接到轮毂(2)的外表面。 此外,提供第二飞行物,其经由橡胶弹簧装置(8)固定到轮毂(2),再次沿周向方向。 为了使这种扭转振动阻尼器能够简单地消除发动机产生的所有振动,承载第一飞轮(3)的橡胶弹簧装置(5)是刚性的,而第二飞行物的橡胶弹簧装置(8) 位于第一飞行器(3)的径向外侧的4)是柔性的。 具有比内部飞翼(3)更大的质量惯性矩的外部飞轮(4)可以经由其橡胶弹簧装置(8)与内部飞翼(3)并联或串联连接。
    • 10. 发明授权
    • Arrangement for carrying dental implements
    • 携带牙科用具的安排
    • US4571182A
    • 1986-02-18
    • US573827
    • 1984-01-24
    • Stefan BeierFranz-Xaver BoeckhAnton BraunThomas BrunnerDieter HoffmannPeter KiessBernd WagnerHeiner Zinser
    • Stefan BeierFranz-Xaver BoeckhAnton BraunThomas BrunnerDieter HoffmannPeter KiessBernd WagnerHeiner Zinser
    • A61C19/02A61B19/02A61C19/00A61G15/14A61C1/14
    • A61C19/00A61G15/14
    • An arrangement for the carrying of dental implements, consisting of a carrying plate arranged on a supporting member, and which has one side facing upwardly including positioning elements provided for the implements on the upwardly facing plate side thereof. The dental implements which are located on the support plate can consist of hand instruments, for example, probes, mirror, tamping instruments, pincettes or the like. Furthermore, the implements can also be formed of cotton receptacles, medication flasks, waste receptacles, as well as worktool, handpiece and anglepiece supports. The positioning elements for the implements can be arranged directly on the carrying plate or also in flat trays, or can even be formed by the flat trays themselves. As the result of an inclination or supplying relative to the horizontal of the upper surface of the carrying plate, the implements which are arranged thereon can be readily surveyed by the dentist or the assistant, and without having to reach thereover, can be easily directly passed over with the hand or by means of a pincette or forceps, or the like.
    • 一种用于携带牙科用具的装置,包括布置在支撑构件上的承载板,并且其一侧面向上包括设置在工具上的定位元件在其面向上的板侧上。 位于支撑板上的牙科工具可以由例如探头,镜子,捣固器械,小针头等手动仪器组成。 此外,器具还可以由棉花插座,药物瓶,废物容器以及工具,手机和角件支架形成。 用于器具的定位元件可以直接布置在承载板上,也可以布置在平板中,或者甚至可以由平板自身形成。 作为相对于承载板的上表面的水平面的倾斜或供给的结果,布置在其上的工具可以容易地由牙医或助手进行测量,而不必到达其上,可以容易地直接通过 用手或通过钳子或钳子等等。