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1. 发明申请

US20080169582A1 Method and apparatus for making polymeric drug delivery devices having differing morphological structures 审中-公开
标题翻译：制备具有不同形态结构的聚合物药物递送装置的方法和装置
公开(公告)号：US20080169582A1
公开(公告)日：2008-07-17
申请号：US11585056
申请日：2006-10-23
申请人： Vipul Bhupendra Dave , David G. Cook , Brian R. White , Jacob Leidner
发明人： Vipul Bhupendra Dave , David G. Cook , Brian R. White , Jacob Leidner
IPC分类号： B27N3/08 , B28B19/00 , B29C51/00 , B29C53/00
CPC分类号： B29C71/02 , B29C2071/022 , B29K2995/006 , B29L2031/753
摘要： A polymeric medical device is constructed from bioabsorbable polymers. The device is constructed from a tube comprised of at least one polymer. The polymer is treated at pre-determined heating and cooling temperatures to obtain a desired morphology. The morphology or arrangement of the polymeric structure ensures that the device maintains its shape characteristics to ensure proper modeling of the vessel. In particular, the crystallinity of the polymeric structure is adjusted so as to resist recoil. The device can also contain a therapeutic agent dispersed throughout the structure or coated on the structure in such a manner as to elute the therapeutic agent when implanted in an anatomical conduit. The device can also be constructed from a blend of polymers and other agents such as plasticizers.
摘要翻译：聚合物医疗器械由生物可吸收聚合物构成。该装置由包含至少一种聚合物的管构成。在预定的加热和冷却温度下处理聚合物以获得所需的形态。聚合物结构的形态或布置确保了该装置保持其形状特征以确保容器的适当建模。特别地，调节聚合物结构的结晶度以抵抗反冲。该装置还可以包含分散在整个结构中的治疗剂或涂覆在结构上，以便当植入解剖导管时洗脱治疗剂。该装置还可以由聚合物和其它试剂如增塑剂的混合物构成。

2. 发明申请

US20080102035A1 Medical device having discrete regions 审中-公开
标题翻译：具有离散区域的医疗设备
公开(公告)号：US20080102035A1
公开(公告)日：2008-05-01
申请号：US11590405
申请日：2006-10-31
申请人： Vipul Bhupendra Dave , Chao Chen , Jason Allan Massey , David G. Cook , Jacob Leidner
发明人： Vipul Bhupendra Dave , Chao Chen , Jason Allan Massey , David G. Cook , Jacob Leidner
IPC分类号： A61K49/04 , A61F2/06
CPC分类号： A61K49/0476 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2250/0067 , A61F2250/0098 , A61K49/04 , A61K49/0404
摘要： An apparatus prepares a medical device from a polymeric composition having properties such as increased visibility of the device and the ability to deliver therapeutic and other agents. The device is constructed with additives incorporated into the polymeric structure, such as a material that increases visibility of the device, while still maintaining desired mechanical characteristics such as high radial stiffness, minimized recoil values, and improved flexibility. The device can assume a wide range of geometries that are adaptable to various loading conditions In order to include performance-enhancing additives to the medical device without affecting mechanical performance, the additives are localized in discrete regions of a polymer structure from which a medical device will be formed. For example, a medical device can be prepared from a polymer form such as a tube containing radiopaque agent localized at its ends or in a desired pattern along the device.
摘要翻译：一种装置从具有诸如提高装置的可见性和递送治疗剂和其它药剂的能力的性质的聚合物组合物制备医疗装置。该装置由结合到聚合物结构中的添加剂构成，例如提高装置的可视性的材料，同时仍然保持期望的机械特性，例如高径向刚度，最小反冲值和改善的柔性。该装置可以采用适用于各种加载条件的宽范围的几何形状。为了将性能增强添加剂包括在医疗装置中而不影响机械性能，添加剂定位在聚合物结构的离散区域中，医疗装置将从该区域形成。例如，医疗装置可以由聚合物形式制备，例如含有不透射线剂的管，其位于其末端或沿着该装置所需的图案。

3. 发明授权

US06441091B1 Eraser 有权
标题翻译：橡皮
公开(公告)号：US06441091B1
公开(公告)日：2002-08-27
申请号：US09917109
申请日：2001-07-27
申请人： Jacob Leidner , David G. Cook , Luis Rodrigo Pineiro
发明人： Jacob Leidner , David G. Cook , Luis Rodrigo Pineiro
IPC分类号： C08L5300
CPC分类号： C08L53/025 , C08L2666/02 , C08L2666/04
摘要： An eraser composition comprising 22-41 wt % styrene-ethylene/butylene-styrene block copolymer, 5-15 wt % ethylene/propylene copolymer, 30-50 wt % calcium carbonate, 10-25 wt % factice; and 0.1-7 wt % pumice is provided. The eraser composition optionally contains up to 1 wt % titanium dioxide. The eraser composition preferably has a hardness of from 70 to 85 Shore A.
摘要翻译：包含22-41重量％苯乙烯 - 乙烯/丁烯 - 苯乙烯嵌段共聚物，5-15重量％乙烯/丙烯共聚物，30-50重量％碳酸钙，10-25重量％实施例的橡皮擦组合物; 并提供0.1-7重量％的浮石。橡皮擦组合物任选地含有至多1重量％的二氧化钛。橡皮擦组合物优选具有70至85肖氏硬度的硬度。

4. 发明授权

US6117535A Biocompatible devices 失效
标题翻译：生物兼容设备
公开(公告)号：US6117535A
公开(公告)日：2000-09-12
申请号：US7220
申请日：1998-01-14
申请人： Michael Szycher , Alan Edwards , Donald Dempsey , Jacob Leidner , David G. Cook
发明人： Michael Szycher , Alan Edwards , Donald Dempsey , Jacob Leidner , David G. Cook
IPC分类号： A61F2/06 , A61L27/18 , A61L27/40 , A61L27/50
CPC分类号： A61L27/18 , A61F2/06 , A61L27/40 , A61L27/507 , Y10T428/249941 , Y10T428/249942
摘要： Filament-reinforced biomedical devices, and methods of making them.
摘要翻译：细丝增强生物医学装置及其制造方法。

5. 发明授权

US5921621A Collapsible chair 失效
标题翻译：折叠椅
公开(公告)号：US5921621A
公开(公告)日：1999-07-13
申请号：US120034
申请日：1998-07-21
申请人： David G. Cook , Margaret J. Cook
发明人： David G. Cook , Margaret J. Cook
IPC分类号： A47C9/10 , A47C4/38
CPC分类号： A47C4/286
摘要： A lightweight, collapsible chair with four legs supporting the corners of a square seat and a back cantilevered from a single leg, placed diagonally over and across the square seat, and positioned between the diagonal and the single leg so that the user straddles the front leg and places his body weight in the center of the seat, thereby contributing to chair comfort and stability.
摘要翻译：一个轻巧的，可折叠的椅子，四条腿支撑一个方形座椅的角落，一个从一个腿部悬垂的后背，斜对角地放置在正方形座椅上，并且位于对角线和单腿之间，以便使用者跨越前腿并将他的体重放置在座位的中心，从而有助于椅子的舒适性和稳定性。

6. 发明授权

US5109556A Camp cot with adjustable to tensioning 失效
标题翻译： Camp可调节张紧张力
公开(公告)号：US5109556A
公开(公告)日：1992-05-05
申请号：US665417
申请日：1991-03-05
申请人： David G. Cook
发明人： David G. Cook
IPC分类号： A47C17/68 , A47C19/00 , A47C19/12
CPC分类号： A47C19/005 , A47C17/68
摘要： A light weight, collapsible, full-size cot with telescoping side rails permanently attached within sleeves at each side of the fabric top, and transverse leg assemblies which support and push apart the side rails by a finely controlled pivoting action to stretch the fabric top to the particular degree of tautness suitable to each cot user.
摘要翻译：一个重量轻，可折叠的全尺寸婴儿床，伸缩式侧轨永久地连接在织物顶部每侧的套筒内，以及横向腿组件，其通过精细控制的枢转动作支撑并推开侧轨，以将织物顶部拉伸至适合每个婴儿床用户的特定程度的紧张度。

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