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    • 2. 发明申请
    • Medical device having discrete regions
    • 具有离散区域的医疗设备
    • US20080102035A1
    • 2008-05-01
    • US11590405
    • 2006-10-31
    • Vipul Bhupendra DaveChao ChenJason Allan MasseyDavid G. CookJacob Leidner
    • Vipul Bhupendra DaveChao ChenJason Allan MasseyDavid G. CookJacob Leidner
    • A61K49/04A61F2/06
    • A61K49/0476A61F2/91A61F2/915A61F2002/91508A61F2250/0067A61F2250/0098A61K49/04A61K49/0404
    • An apparatus prepares a medical device from a polymeric composition having properties such as increased visibility of the device and the ability to deliver therapeutic and other agents. The device is constructed with additives incorporated into the polymeric structure, such as a material that increases visibility of the device, while still maintaining desired mechanical characteristics such as high radial stiffness, minimized recoil values, and improved flexibility. The device can assume a wide range of geometries that are adaptable to various loading conditions In order to include performance-enhancing additives to the medical device without affecting mechanical performance, the additives are localized in discrete regions of a polymer structure from which a medical device will be formed. For example, a medical device can be prepared from a polymer form such as a tube containing radiopaque agent localized at its ends or in a desired pattern along the device.
    • 一种装置从具有诸如提高装置的可见性和递送治疗剂和其它药剂的能力的性质的聚合物组合物制备医疗装置。 该装置由结合到聚合物结构中的添加剂构成,例如提高装置的可视性的材料,同时仍然保持期望的机械特性,例如高径向刚度,最小反冲值和改善的柔性。 该装置可以采用适用于各种加载条件的宽范围的几何形状。为了将性能增强添加剂包括在医疗装置中而不影响机械性能,添加剂定位在聚合物结构的离散区域中,医疗装置将从该区域 形成。 例如,医疗装置可以由聚合物形式制备,例如含有不透射线剂的管,其位于其末端或沿着该装置所需的图案。
    • 6. 发明授权
    • Erasable colored pencil lead
    • 可擦色彩铅笔铅笔
    • US06271286B1
    • 2001-08-07
    • US09338181
    • 1999-06-22
    • Jacob LeidnerDavid Hacker
    • Jacob LeidnerDavid Hacker
    • C09D1300
    • C09D13/00
    • The present invention provides an erasable colored pencil lead composition comprising a colorant, one or more binder resins, a fibrillatable or fibrillated material, and a filler. The colored pencil lead of the present invention produces marks on paper, which are easily erased by ordinary pencil eraser. The mark made using the composition has a cohesive nature that assists in the removal from paper in sheet or film like sections by the use of an ordinary eraser without smearing or leaving a residue. In a preferred embodiment, the composition is free or substantially free of low melting waxes or wax like materials. Examples of suitable binder resins include high density polyethylene, low density polyethylene, polypropylene, and high melting waxes. Examples of fibrillated or fibrillatable materials include fibrillatable or fibrillated polytetrafluoroethylene and ethylene-vinyl acetate copolymer. The colored pencil lead composition may further include a lubricant. Examples of suitable lubricants include particulate lubricants such as micronized PTFE and non-particulate lubricants such as alkoxylated materials, e.g., polyethylene glycols. The present invention further provides a process for using the colored pencil lead composition. The present invention further provides a process for preparing the colored pencil lead of the present invention.
    • 本发明提供了一种可擦色的铅笔铅组合物,其包含着色剂,一种或多种粘合剂树脂,可原纤化或原纤化材料和填料。 本发明的彩色铅笔在纸上产生标记,其易于被普通的铅笔擦除。 使用该组合物制成的标记具有粘性,其有助于通过使用普通橡皮擦在片或片状部分中从纸中除去而不会污迹或留下残留物。 在优选的实施方案中,组合物是游离的或基本上不含低熔点蜡或类似蜡的材料。 合适的粘合剂树脂的实例包括高密度聚乙烯,低密度聚乙烯,聚丙烯和高熔点蜡。 原纤化或可原纤化材料的实例包括可原纤化或原纤化的聚四氟乙烯和乙烯 - 乙酸乙烯酯共聚物。 彩色铅笔铅组合物还可以包括润滑剂。 合适的润滑剂的实例包括颗粒润滑剂,例如微粉化PTFE和非颗粒润滑剂,例如烷氧基化材料,例如聚乙二醇。 本发明还提供使用彩色铅笔铅组合物的方法。 本发明还提供了制备本发明的彩色铅笔的方法。
    • 7. 发明授权
    • Erasable colored pencil lead
    • 可擦色彩铅笔铅笔
    • US6011084A
    • 2000-01-04
    • US105704
    • 1998-06-26
    • Jacob LeidnerDavid Hacker
    • Jacob LeidnerDavid Hacker
    • C09D13/00C08K7/02C08L27/18
    • C09D13/00
    • The present invention provides a colored pencil lead composition comprising a colorant, one or more binder resins, a fibrillatable or fibrillated material, a non-fibrillatable particulate lubricant, and a filler. An example of a suitable binder resin is high density polyethylene, and an example of a fibrillated or fibrillatable material is fibrillatable polytetrafluoroethylene. An example of a non-fibrillatable particulate lubricant is micronized polytetrafluoroethylene. The colored pencil lead of the present invention produces marks on paper which are easily erased by ordinary pencil eraser. The present invention further provides a process for preparing the colored pencil lead of the present invention comprising compounding the colorant, the binder resin or resins, the fibrillatable or fibrillated material, the non-fibrillatable particulate lubricant, and the filler to obtain a blend and forming the pencil lead from the blend.
    • 本发明提供一种着色铅笔铅组合物,其包含着色剂,一种或多种粘合剂树脂,可原纤化或原纤化材料,不可原纤化的颗粒润滑剂和填料。 合适的粘合剂树脂的实例是高密度聚乙烯,并且原纤化或可原纤化材料的实例是可原纤化的聚四氟乙烯。 非可原纤化颗粒润滑剂的实例是微粉化聚四氟乙烯。 本发明的彩色铅笔在纸上产生标记,容易被普通的铅笔擦除。 本发明还提供了一种制备本发明的着色铅笔铅的方法,其包括将着色剂,粘合剂树脂或树脂,可原纤化或原纤化材料,不可原纤化的颗粒润滑剂和填料混合以获得共混物和成型 铅笔铅笔从混合。
    • 10. 发明授权
    • Erasable colored pencil lead
    • 可擦色彩铅笔铅笔
    • US06262143B1
    • 2001-07-17
    • US09197283
    • 1998-11-20
    • Jacob LeidnerDavid Hacker
    • Jacob LeidnerDavid Hacker
    • C09D1300
    • C09D13/00
    • The present invention provides an erasable colored pencil lead composition comprising a colorant, one or more binder resins, a fibrillatable or fibrillated material, and a filler. The colored pencil lead of the present invention produces marks on paper which are easily erased by ordinary pencil eraser. The mark made using the composition has a cohesive nature which assists in the removal from paper in sheet or film like sections by the use of an ordinary eraser without smearing or leaving a residue. In a preferred embodiment, the composition is free or substantially free of low melting waxes or wax like materials. Examples of suitable binder resins include high density polyethylene, low density polyethylene, polypropylene, and high melting waxes. Examples of fibrillated or fibrillatable materials include fibrillatable or fibrillated polytetrafluoroethylene and ethylene-vinyl acetate copolymer. The colored pencil lead composition may further include a lubricant. Examples of the lubricants include micronized PTFE and polyethylene glycols. The present invention further provides a process for using the colored pencil lead composition. The present invention further provides a process for preparing the colored pencil lead of the present invention.
    • 本发明提供了一种可擦色的铅笔铅组合物,其包含着色剂,一种或多种粘合剂树脂,可原纤化或原纤化材料和填料。 本发明的彩色铅笔在纸上产生标记,容易被普通的铅笔擦除。 使用该组合物制成的标记具有内聚性质,其有助于通过使用普通橡皮擦将片材或片状部分中的纸从纸上或片状部分除去,而不会弄脏或留下残留物。 在优选的实施方案中,组合物是游离的或基本上不含低熔点蜡或类似蜡的材料。 合适的粘合剂树脂的实例包括高密度聚乙烯,低密度聚乙烯,聚丙烯和高熔点蜡。 原纤化或可原纤化材料的实例包括可原纤化或原纤化的聚四氟乙烯和乙烯 - 乙酸乙烯酯共聚物。 彩色铅笔铅组合物还可以包括润滑剂。 润滑剂的实例包括微粉化PTFE和聚乙二醇。 本发明还提供使用彩色铅笔铅组合物的方法。 本发明还提供了制备本发明的彩色铅笔的方法。