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    • 1. 发明申请
    • Medical device having discrete regions
    • 具有离散区域的医疗设备
    • US20080102035A1
    • 2008-05-01
    • US11590405
    • 2006-10-31
    • Vipul Bhupendra DaveChao ChenJason Allan MasseyDavid G. CookJacob Leidner
    • Vipul Bhupendra DaveChao ChenJason Allan MasseyDavid G. CookJacob Leidner
    • A61K49/04A61F2/06
    • A61K49/0476A61F2/91A61F2/915A61F2002/91508A61F2250/0067A61F2250/0098A61K49/04A61K49/0404
    • An apparatus prepares a medical device from a polymeric composition having properties such as increased visibility of the device and the ability to deliver therapeutic and other agents. The device is constructed with additives incorporated into the polymeric structure, such as a material that increases visibility of the device, while still maintaining desired mechanical characteristics such as high radial stiffness, minimized recoil values, and improved flexibility. The device can assume a wide range of geometries that are adaptable to various loading conditions In order to include performance-enhancing additives to the medical device without affecting mechanical performance, the additives are localized in discrete regions of a polymer structure from which a medical device will be formed. For example, a medical device can be prepared from a polymer form such as a tube containing radiopaque agent localized at its ends or in a desired pattern along the device.
    • 一种装置从具有诸如提高装置的可见性和递送治疗剂和其它药剂的能力的性质的聚合物组合物制备医疗装置。 该装置由结合到聚合物结构中的添加剂构成,例如提高装置的可视性的材料,同时仍然保持期望的机械特性,例如高径向刚度,最小反冲值和改善的柔性。 该装置可以采用适用于各种加载条件的宽范围的几何形状。为了将性能增强添加剂包括在医疗装置中而不影响机械性能,添加剂定位在聚合物结构的离散区域中,医疗装置将从该区域 形成。 例如,医疗装置可以由聚合物形式制备,例如含有不透射线剂的管,其位于其末端或沿着该装置所需的图案。