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1. 发明授权

US06562031B2 Guide wire system for RF recanalization of vascular blockages 有权
标题翻译：导管系统用于射频再通血管阻塞
公开(公告)号：US06562031B2
公开(公告)日：2003-05-13
申请号：US09814142
申请日：2001-03-20
申请人： Verivada Chandrasekaran , Zihong Guo , Brooke Qin Ren , Byron Fedie
发明人： Verivada Chandrasekaran , Zihong Guo , Brooke Qin Ren , Byron Fedie
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2017/22038 , A61B2017/22094 , A61B2018/00214 , A61B2018/00261 , A61B2018/00279 , A61B2018/00285 , A61B2018/0041 , A61B2018/00422 , A61B2018/00625 , A61B2018/1213 , A61B2018/1253 , A61B2018/1435 , A61B2018/144 , A61M25/09 , A61M25/10 , A61M2025/1047
摘要： A system for recanalizing an occluded blood vessel including a centering catheter employed to center an ablative guide wire within the blood vessel as the guide wire traverses the occlusion. The centering catheter includes a catheter body with an operative lumen through which the ablative guide wire is slidingly disposed. The centering catheter further includes a distally disposed centering mechanism that, when activated, centers the ablative guide wire within the blood vessel as it traverses the occlusion. The centering mechanism can comprise various embodiments including a single inflatable balloon or segmented inflatable balloon, which is in fluid communication with an inflation lumen. An airless preparation lumen may be disposed within the inflation lumen for ease of centering catheter preparation. The ablative guide wire includes insulation that is preferably formed of heat shrink tubing, which is stretched prior or concurrently with the heating process. The ablative guide wire includes a distal ablation tip having a non-traumatic structure and at least one discontinuous feature for creating high current densities for more efficient tissue ablation.
摘要翻译：包括定心导管的闭塞血管再通的系统，其用于在引导线穿过闭塞时使血管内的消融引导线居中。定心导管包括具有操作腔的导管主体，消融导丝通过该导管本体滑动地设置。定心导管进一步包括一个向远侧配置的定中心机构，当被激活时，该消融导丝在穿过该闭塞时在该血管内居中。定心机构可以包括各种实施例，包括与充气腔流体连通的单个可充气球囊或分段的可充气球囊。可以在充气腔内设置无空气制剂腔，以便于使导管制剂居中。烧蚀导丝包括优选由热收缩管形成的绝缘体，其在加热过程之前或同时被拉伸。烧蚀导丝包括具有非创伤性结构的远端消融尖端和用于产生高电流密度以用于更有效的组织消融的至少一个不连续特征。

2. 发明授权

US06210408B1 Guide wire system for RF recanalization of vascular blockages 失效
公开(公告)号：US06210408B1
公开(公告)日：2001-04-03
申请号：US09256977
申请日：1999-02-24
申请人： Verivada Chandrasekaran , Zihong Guo , Brooke Qin Ren , Byron Fedie
发明人： Verivada Chandrasekaran , Zihong Guo , Brooke Qin Ren , Byron Fedie
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2017/22038 , A61B2017/22094 , A61B2018/00214 , A61B2018/00261 , A61B2018/00279 , A61B2018/00285 , A61B2018/0041 , A61B2018/00422 , A61B2018/00625 , A61B2018/1213 , A61B2018/1253 , A61B2018/1435 , A61B2018/144 , A61M25/09 , A61M25/10 , A61M2025/1047
摘要： A system for recanalizing an occluded blood vessel including a centering catheter employed to center an ablative guide wire within the blood vessel as the guide wire traverses the occlusion. The centering catheter includes a catheter body with an operative lumen through which the ablative guide wire is slidingly disposed. The centering catheter further includes a distally disposed centering mechanism that, when activated, centers the ablative guide wire within the blood vessel as it traverses the occlusion. The centering mechanism can comprise various embodiments including a single inflatable balloon or segmented inflatable balloon, which is in fluid communication with an inflation lumen. An airless preparation lumen may be disposed within the inflation lumen for ease of centering catheter preparation. The ablative guide wire includes insulation that is preferably formed of heat shrink tubing, which is stretched prior or concurrently with the heating process. The ablative guide wire includes a distal ablation tip having a non-traumatic structure and at least one discontinuous feature for creating high current densities for more efficient tissue ablation.

3. 发明授权

US5968012A Balloon catheter with adjustable shaft 失效
标题翻译：气球导管带可调轴
公开(公告)号：US5968012A
公开(公告)日：1999-10-19
申请号：US917075
申请日：1997-08-22
申请人： Brooke Qin Ren , Jon P. St. Germain , Scott A. Olson
发明人： Brooke Qin Ren , Jon P. St. Germain , Scott A. Olson
IPC分类号： A61F2/958 , A61M25/00 , A61M29/00
CPC分类号： A61M25/104 , A61M2025/1068 , A61M25/0043
摘要： The present invention provides a balloon catheter with a length compensator, which can be an accordion section or a slipping sleeve section. In the accordion section embodiment of the invention, the outer shaft of the catheter includes an accordion section positioned proximally of the balloon. In this embodiment the length compensator is comprised of the accordion section and the outer shaft between the accordion section and the point where the proximal end of the balloon is attached to the outer shaft. The distal end of the balloon is attached to an inner shaft. As the balloon is inflated the accordion section expands to adjust the axial length of the length compensator to compensate for the movement of the two ends of the balloon towards each other. In the slipping sleeve embodiment of the invention, the inner shaft of the catheter includes a slipping sleeve section positioned proximally of the point where the distal end of the balloon is connected to the inner shaft. As the balloon is expanded, the slipping sleeve section contracts, adjusting the axial length of the length compensator to compensate for the shrinkage of the balloon as it expands into contact with the vasculature.
摘要翻译：本发明提供一种具有长度补偿器的球囊导管，其可以是手风琴部分或滑动套筒部分。在本发明的手风琴部实施例中，导管的外轴包括位于气囊近侧的手风琴部。在该实施例中，长度补偿器包括手风琴部分和手风琴部分之间的外轴以及球囊的近端附接到外轴的点。气囊的远端附接到内轴。当气球膨胀时，手风琴部分膨胀以调节长度补偿器的轴向长度，以补偿气球的两个端部朝向彼此的移动。在本发明的滑动套筒的实施例中，导管的内轴包括位于球囊的远端与内轴连接的点的近侧的滑动套筒部分。当气囊膨胀时，滑动套管部分收缩，调节长度补偿器的轴向长度以补偿球囊膨胀成与脉管系统接触时的收缩。

4. 发明授权

US06315790B1 Radiopaque marker bands 失效
标题翻译：不透射线的标记带
公开(公告)号：US06315790B1
公开(公告)日：2001-11-13
申请号：US09327234
申请日：1999-06-07
申请人： Brent C. Gerberding , Brooke Qin Ren
发明人： Brent C. Gerberding , Brooke Qin Ren
IPC分类号： A61F1100
CPC分类号： A61F2/958 , A61B90/39 , A61F2002/9583 , A61F2002/9586 , A61F2250/0098
摘要： A stent delivery system which includes a catheter having a radially expandable stent coaxially arranged near a distal end of the catheter. The catheter is equipped with at least one stent securement hub disposed about a portion of the distal end of the catheter underlying the stent. Each of the at least one stent securement hubs being made of a radiopaque polymer.
摘要翻译：一种支架输送系统，其包括具有在导管的远端附近同轴布置的径向可扩张支架的导管。该导管配备有至少一个支架固定毂，其设置在支架下方的导管的远端的一部分周围。所述至少一个支架固定座中的每一个由不透射线的聚合物制成。

5. 发明授权

US6159219A Stent retrieval device 失效
标题翻译：支架检索装置
公开(公告)号：US6159219A
公开(公告)日：2000-12-12
申请号：US857791
申请日：1997-05-16
申请人： Brooke Qin Ren
发明人： Brooke Qin Ren
IPC分类号： A61F2/06 , A61F2/84 , A61F11/00
CPC分类号： A61F2/958 , A61F2/95
摘要： The present invention provides a device and method for retrieving a balloon expandable stent which has been misplaced. It utilizes a balloon catheter which is sized to fit into the inside diameter of a stent to be retrieved. The stent has proximal and distal ends and a predefined expansion force threshold which must be exceeded in order to radially expand the stent. The balloon has proximal and distal ends, a greater axial length than the stent to be retrieved, and is made of a compliant material which will deform at less than the predefined expansion force threshold of the stent.
摘要翻译：本发明提供了一种用于取回已放错位置的球囊可扩张支架的装置和方法。它使用气囊导管，其尺寸适合于待检索的支架的内径。支架具有近端和远端以及必须超过预定的膨胀力阈值，以便径向扩张支架。气囊具有近端和远端，比待回收的支架更大的轴向长度，并且由柔性材料制成，该柔性材料将以小于支架的预定的扩张力阈值而变形。

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