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1. 发明授权

US5968012A Balloon catheter with adjustable shaft 失效
标题翻译：气球导管带可调轴
公开(公告)号：US5968012A
公开(公告)日：1999-10-19
申请号：US917075
申请日：1997-08-22
申请人： Brooke Qin Ren , Jon P. St. Germain , Scott A. Olson
发明人： Brooke Qin Ren , Jon P. St. Germain , Scott A. Olson
IPC分类号： A61F2/958 , A61M25/00 , A61M29/00
CPC分类号： A61M25/104 , A61M2025/1068 , A61M25/0043
摘要： The present invention provides a balloon catheter with a length compensator, which can be an accordion section or a slipping sleeve section. In the accordion section embodiment of the invention, the outer shaft of the catheter includes an accordion section positioned proximally of the balloon. In this embodiment the length compensator is comprised of the accordion section and the outer shaft between the accordion section and the point where the proximal end of the balloon is attached to the outer shaft. The distal end of the balloon is attached to an inner shaft. As the balloon is inflated the accordion section expands to adjust the axial length of the length compensator to compensate for the movement of the two ends of the balloon towards each other. In the slipping sleeve embodiment of the invention, the inner shaft of the catheter includes a slipping sleeve section positioned proximally of the point where the distal end of the balloon is connected to the inner shaft. As the balloon is expanded, the slipping sleeve section contracts, adjusting the axial length of the length compensator to compensate for the shrinkage of the balloon as it expands into contact with the vasculature.
摘要翻译：本发明提供一种具有长度补偿器的球囊导管，其可以是手风琴部分或滑动套筒部分。在本发明的手风琴部实施例中，导管的外轴包括位于气囊近侧的手风琴部。在该实施例中，长度补偿器包括手风琴部分和手风琴部分之间的外轴以及球囊的近端附接到外轴的点。气囊的远端附接到内轴。当气球膨胀时，手风琴部分膨胀以调节长度补偿器的轴向长度，以补偿气球的两个端部朝向彼此的移动。在本发明的滑动套筒的实施例中，导管的内轴包括位于球囊的远端与内轴连接的点的近侧的滑动套筒部分。当气囊膨胀时，滑动套管部分收缩，调节长度补偿器的轴向长度以补偿球囊膨胀成与脉管系统接触时的收缩。

2. 发明授权

US5534007A Stent deployment catheter with collapsible sheath 失效
标题翻译：支架部署导管与可折叠护套
公开(公告)号：US5534007A
公开(公告)日：1996-07-09
申请号：US444822
申请日：1995-05-18
申请人： Jon P. St. Germain , Scott A. Olson
发明人： Jon P. St. Germain , Scott A. Olson
IPC分类号： A61F2/82 , A61F2/06 , A61F2/84 , A61B17/00
CPC分类号： A61F2/966 , A61F2/95 , A61M2025/0183
摘要： The present invention provides an improved stent delivery catheter. The stent delivery system comprises a catheter having a stent receiving portion adapted to receive a stent near the distal end of the catheter and a stent concentrically arranged around the catheter within the stent receiving portion. The stent delivery system further comprises a proximal outer sheath, a retractable distal sheath surrounding at least a portion of the stent and containing the stent in its reduced delivery configuration and a pull back means connected to the retractable distal sheath. The system further comprises a collapsible sheath concentrically arranged around the catheter and located between the retractable distal sheath and the proximal outer sheath, whereby when the pull back means is pulled proximally the distal sheath is retracted, causing the collapsible sheath to collapse and freeing the stent for delivery.
摘要翻译：本发明提供一种改进的支架输送导管。所述支架输送系统包括具有适于在所述导管的远端附近接收支架的支架接收部分的导管和在所述支架接收部分内围绕所述导管同心布置的支架。支架输送系统还包括近端外护套，围绕支架的至少一部分并且以其减小的输送构型容纳支架并且连接到可缩回的远端护套的拉回装置的可缩回的远端鞘。系统还包括同心地布置在导管周围并位于可缩回的远侧护套和近侧外护套之间的可折叠护套，由此当拉回装置向近侧被拉动时，远侧护套被缩回，导致可收缩护套塌陷并释放支架交付。

3. 发明授权

US08616411B1 Collapsible tube retaining device 有权
标题翻译：可折叠管保持装置
公开(公告)号：US08616411B1
公开(公告)日：2013-12-31
申请号：US12731142
申请日：2010-03-24
申请人： Jon P. St. Germain
发明人： Jon P. St. Germain
IPC分类号： B65D35/32
CPC分类号： B65D35/32
摘要： A device for use in dispensing the contents of a collapsible tube comprises a hollow cylindrical member for winding about the tube. The cylindrical member includes an elongated slot for receiving a tail portion of the collapsible tube, as well as a plurality of notches positioned along a periphery of a first end of the cylindrical member. An elastic flexible tether anchors to a second end of the cylindrical member. The tether is positionable between at least one of the plurality of notches contained within the first end of the cylindrical member. After winding, the tether is stretched and positioned between a selected notch, thereby securing the tether to the first end of the cylindrical member and retaining the thusly wound tube in a selected position. The hollow cylinder may also include a floss dispensing member positionable therein, as well as act as a storage compartment.
摘要翻译：用于分配可折叠管的内容物的装置包括用于绕管缠绕的中空圆柱形构件。圆柱形构件包括用于容纳可折叠管的尾部的细长狭槽以及沿着圆柱形构件的第一端的周边定位的多个凹口。弹性柔性系绳固定到圆柱形构件的第二端。系绳可定位在容纳在圆柱形构件的第一端部内的多个凹口中的至少一个之间。在卷绕之后，将系绳拉伸并定位在选定的切口之间，从而将系绳固定到圆柱形构件的第一端并将如此缠绕的管保持在选定位置。中空圆柱体还可以包括可定位在其中的牙线分配构件，以及用作储藏室。

4. 发明授权

US07468027B2 Partial aortic occlusion devices and methods for cerebral perfusion augmentation 有权
标题翻译：局部主动脉闭塞装置和脑灌注增强的方法
公开(公告)号：US07468027B2
公开(公告)日：2008-12-23
申请号：US11256549
申请日：2005-10-21
申请人： Denise R. Barbut , Peter T. Keith , Steven W. Berhow , Jon P. St. Germain
发明人： Denise R. Barbut , Peter T. Keith , Steven W. Berhow , Jon P. St. Germain
IPC分类号： A61N1/362 , A61M29/00 , A61M31/00 , A61M37/00
CPC分类号： A61B17/12045 , A61B5/0215 , A61B5/4076 , A61B6/481 , A61B17/12036 , A61B17/12109 , A61B17/12136 , A61B17/12145 , A61B17/1219 , A61B2017/22054 , A61B2090/3966 , A61F7/12 , A61F2002/068 , A61F2007/126 , A61M25/00 , A61M25/003 , A61M25/0032 , A61M25/0068 , A61M25/0069 , A61M25/0074 , A61M25/008 , A61M25/0082 , A61M25/0147 , A61M25/0662 , A61M25/1011 , A61M2025/0002 , A61M2025/0034 , A61M2025/0073 , A61M2025/0081 , A61M2025/1052 , A61M2210/127 , A61M2230/005 , A61M2230/30
摘要： Methods are provided for partial aortic obstruction for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. Alternatively, the methods can be used to partially obstruct aortic blood flow to condition the spinal cord to secrete neuroprotective agents prior to abdominal aortic aneurysm repair. Partial obstruction of a vessel can be accomplished by a device comprising an elongate catheter and a distally mounted expandable member. The expandable member may comprise one or two balloons. Other medical devices, such as an angioplasty, stent, or atherectomy catheter, can be inserted distal the expandable member to provide therapeutic intervention.
摘要翻译：为全脑或局灶性脑缺血患者提供局部主动脉阻塞用于脑灌注增强的方法。或者，所述方法可用于部分阻塞主动脉血流以调节脊髓以在腹主动脉瘤修复之前分泌神经保护剂。容器的部分阻塞可以通过包括细长导管和远侧安装的可扩张构件的装置来实现。可膨胀构件可以包括一个或两个气囊。诸如血管成形术，支架或粥样斑块切除术导管的其它医疗装置可以在可扩张构件的远端插入以提供治疗干预。

5. 发明授权

US07150736B2 Cerebral perfusion augmentation 有权
标题翻译：脑灌注增强
公开(公告)号：US07150736B2
公开(公告)日：2006-12-19
申请号：US11042642
申请日：2005-01-24
申请人： Denise R. Barbut , Peter T. Keith , Steven W. Berhow , Jon P. St. Germain
发明人： Denise R. Barbut , Peter T. Keith , Steven W. Berhow , Jon P. St. Germain
IPC分类号： A61M31/99 , A61N1/362
CPC分类号： A61B17/12045 , A61B5/0215 , A61B5/4076 , A61B6/481 , A61B17/12036 , A61B17/12109 , A61B17/12136 , A61B17/12145 , A61B17/1219 , A61B2017/22054 , A61B2090/3966 , A61F7/12 , A61F2002/068 , A61F2007/126 , A61M25/00 , A61M25/003 , A61M25/0032 , A61M25/0068 , A61M25/0069 , A61M25/0074 , A61M25/008 , A61M25/0082 , A61M25/0147 , A61M25/0662 , A61M25/1011 , A61M2025/0002 , A61M2025/0034 , A61M2025/0073 , A61M2025/0081 , A61M2025/1052 , A61M2210/127 , A61M2230/005 , A61M2230/30
摘要： Methods are provided for partial aortic obstruction for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. Alternatively, the methods can be used to partially obstruct aortic blood flow to condition the spinal cord to secrete neuroprotective agents prior to abdominal aortic aneurysm repair. Partial obstruction of a vessel can be accomplished by a device comprising an elongate catheter and a distally mounted expandable member. The expandable member may comprise one or two balloons. Other medical devices, such as an angioplasty, stent, or atherectomy catheter, can be inserted distal the expandable member to provide therapeutic intervention.
摘要翻译：为全脑或局灶性脑缺血患者提供局部主动脉阻塞用于脑灌注增强的方法。或者，所述方法可用于部分阻塞主动脉血流以调节脊髓以在腹主动脉瘤修复之前分泌神经保护剂。容器的部分阻塞可以通过包括细长导管和远侧安装的可扩张构件的装置来实现。可膨胀构件可以包括一个或两个气囊。诸如血管成形术，支架或粥样斑块切除术导管的其它医疗装置可以在可扩张构件的远端插入以提供治疗干预。

6. 发明授权

US06997945B2 Variable expansion force stent 失效
公开(公告)号：US06997945B2
公开(公告)日：2006-02-14
申请号：US10106162
申请日：2002-03-26
申请人： Jon P. St. Germain
发明人： Jon P. St. Germain
IPC分类号： A61F2/06
CPC分类号： A61F2/88 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/30014 , A61F2002/30093 , A61F2002/30199 , A61F2002/30322 , A61F2002/30324 , A61F2002/30327 , A61F2002/821 , A61F2002/91533 , A61F2002/91558 , A61F2210/0019 , A61F2230/0063 , A61F2250/0018 , A61F2250/0026 , A61F2250/0036 , A61F2250/0039
摘要： A stent having varying outward radial force along its length. In use, the stent can provide greater force in vessel regions requiring greater force and less force in regions requiring less. In particular, more force is provided in the narrowed, center of a stenosis, while not applying too much force to the adjoining healthy tissue area. Greater stent expansion is provided in wider vessel geometries and less stent expansion in narrower regions. Varying force is achieved varying the number of elements, the density of elements, and the thickness of the elements.

7. 发明授权

US06743196B2 Partial aortic occlusion devices and methods for cerebral perfusion augmentation 有权
标题翻译：局部主动脉闭塞装置和脑灌注增强的方法
公开(公告)号：US06743196B2
公开(公告)日：2004-06-01
申请号：US09841929
申请日：2001-04-24
申请人： Denise R. Barbut , Peter T. Keith , Steven W. Berhow , Jon P. St. Germain
发明人： Denise R. Barbut , Peter T. Keith , Steven W. Berhow , Jon P. St. Germain
IPC分类号： A61M2900
CPC分类号： A61B17/12045 , A61B5/0215 , A61B5/4076 , A61B6/481 , A61B17/12036 , A61B17/12109 , A61B17/12136 , A61B17/12145 , A61B17/1219 , A61B2017/22054 , A61B2090/3966 , A61F7/12 , A61F2002/068 , A61F2007/126 , A61M25/00 , A61M25/003 , A61M25/0032 , A61M25/0068 , A61M25/0069 , A61M25/0074 , A61M25/008 , A61M25/0082 , A61M25/0147 , A61M25/0662 , A61M25/1011 , A61M2025/0002 , A61M2025/0034 , A61M2025/0073 , A61M2025/0081 , A61M2025/1052 , A61M2210/127 , A61M2230/005 , A61M2230/30
摘要： Methods are provided for partial aortic obstruction for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. Alternatively, the methods can be used to partially obstruct aortic blood flow to condition the spinal cord to secrete neuroprotective agents prior to abdominal aortic aneurysm repair. Partial obstruction of a vessel can be accomplished by a device comprising an elongate catheter and a distally mounted expandable member. The expandable member may comprise one or two balloons. Other medical devices, such as an angioplasty, stent, or atherectomy catheter, can be inserted distal the expandable member to provide therapeutic intervention.
摘要翻译：为全脑或局灶性脑缺血患者提供局部主动脉阻塞用于脑灌注增强的方法。或者，所述方法可用于部分阻塞主动脉血流以调节脊髓以在腹主动脉瘤修复之前分泌神经保护剂。容器的部分阻塞可以通过包括细长导管和远侧安装的可扩张构件的装置来实现。可膨胀构件可以包括一个或两个气囊。诸如血管成形术，支架或粥样斑块切除术导管的其它医疗装置可以在可扩张构件的远端插入以提供治疗干预。

8. 发明授权

US6146403A Variable expansion force stent 有权
公开(公告)号：US6146403A
公开(公告)日：2000-11-14
申请号：US193504
申请日：1998-11-17
申请人： Jon P. St. Germain
发明人： Jon P. St. Germain
IPC分类号： A61F2/00 , A61F2/82 , A61F2/88 , A61F2/90 , F61M29/00
CPC分类号： A61F2/88 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/30014 , A61F2002/30093 , A61F2002/30199 , A61F2002/30322 , A61F2002/30324 , A61F2002/30327 , A61F2002/821 , A61F2002/91533 , A61F2002/91558 , A61F2210/0019 , A61F2230/0063 , A61F2250/0018 , A61F2250/0026 , A61F2250/0036 , A61F2250/0039
摘要： A stent having varying outward radial force along its length. In use, the stent can provide greater force in vessel regions requiring greater force and less force in regions requiring less. In particular, more force is provided in the narrowed, center of a stenosis, while not applying too much force to the adjoining healthy tissue area. Greater stent expansion is provided in wider vessel geometries and less stent expansion in narrower regions. Varying force is achieved varying the number of elements, the density of elements, and the thickness of the elements.

9. 发明申请

US20110106132A1 PARTIAL AORTIC OCCLUSION DEVICES AND METHODS FOR CEREBRAL PERFUSION AUGMENTATION 有权
标题翻译：局部放射治疗装置及方法
公开(公告)号：US20110106132A1
公开(公告)日：2011-05-05
申请号：US12987849
申请日：2011-01-10
申请人： Denise R. Barbut , Peter T. Keith , Steven W. Berhow , Jon P. St. Germain
发明人： Denise R. Barbut , Peter T. Keith , Steven W. Berhow , Jon P. St. Germain
IPC分类号： A61M29/02
CPC分类号： A61B17/12045 , A61B5/0215 , A61B5/4076 , A61B6/481 , A61B17/12036 , A61B17/12109 , A61B17/12136 , A61B17/12145 , A61B17/1219 , A61B2017/22054 , A61B2090/3966 , A61F7/12 , A61F2002/068 , A61F2007/126 , A61M25/00 , A61M25/003 , A61M25/0032 , A61M25/0068 , A61M25/0069 , A61M25/0074 , A61M25/008 , A61M25/0082 , A61M25/0147 , A61M25/0662 , A61M25/1011 , A61M2025/0002 , A61M2025/0034 , A61M2025/0073 , A61M2025/0081 , A61M2025/1052 , A61M2210/127 , A61M2230/005 , A61M2230/30
摘要： Methods are provided for partial aortic obstruction for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. Alternatively, the methods can be used to partially obstruct aortic blood flow to condition the spinal cord to secrete neuroprotective agents prior to abdominal aortic aneurysm repair. Partial obstruction of a vessel can be accomplished by a device comprising an elongate catheter and a distally mounted expandable member. The expandable member may comprise one or two balloons. Other medical devices, such as an angioplasty, stent, or atherectomy catheter, can be inserted distal the expandable member to provide therapeutic intervention.
摘要翻译：为全脑或局灶性脑缺血患者提供局部主动脉阻塞用于脑灌注增强的方法。或者，所述方法可用于部分阻塞主动脉血流以调节脊髓以在腹主动脉瘤修复之前分泌神经保护剂。容器的部分阻塞可以通过包括细长导管和远侧安装的可扩张构件的装置来实现。可膨胀构件可以包括一个或两个气囊。诸如血管成形术，支架或粥样斑块切除术导管的其它医疗装置可以在可扩张构件的远端插入以提供治疗干预。

10. 发明授权

US07485130B2 Variable expansion force stent 有权
公开(公告)号：US07485130B2
公开(公告)日：2009-02-03
申请号：US11318196
申请日：2005-12-23
申请人： Jon P. St. Germain
发明人： Jon P. St. Germain
IPC分类号： A61M29/00
CPC分类号： A61F2/88 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/30014 , A61F2002/30093 , A61F2002/30199 , A61F2002/30322 , A61F2002/30324 , A61F2002/30327 , A61F2002/821 , A61F2002/91533 , A61F2002/91558 , A61F2210/0019 , A61F2230/0063 , A61F2250/0018 , A61F2250/0026 , A61F2250/0036 , A61F2250/0039
摘要： A stent having varying outward radial force along its length. In use, the stent can provide greater force in vessel regions requiring greater force and less force in regions requiring less. In particular, more force is provided in the narrowed, center of a stenosis, while not applying too much force to the adjoining healthy tissue area. Greater stent expansion is provided in wider vessel geometries and less stent expansion in narrower regions. Varying force is achieved varying the number of elements, the density of elements, and the thickness of the elements.

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