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1. 发明授权

US08308765B2 Apparatus and methods for positioning and securing anchors 有权
标题翻译：用于定位和固定锚固件的装置和方法
公开(公告)号：US08308765B2
公开(公告)日：2012-11-13
申请号：US10840950
申请日：2004-05-07
申请人： Vahid Saadat , Tracy D. Maahs , Richard C. Ewers , Marvin C. Elmers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Cang C. Lam
发明人： Vahid Saadat , Tracy D. Maahs , Richard C. Ewers , Marvin C. Elmers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Cang C. Lam
IPC分类号： A61B17/04
CPC分类号： A61B17/08 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/10 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488 , Y10T24/39 , Y10T24/3936
摘要： Apparatus and methods for positioning and securing anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This unidirectional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.
摘要翻译：用于定位和固定锚固件的装置和方法适于被输送并植入到组织中，特别是患者胃肠系统内的组织中。锚固件适于在缝合线上单向滑动，使得组织褶皱可以在锚固件之间束紧。如果锚固件被拉动，推动或沿着缝合线沿相反方向被推动，锚固件本身内的定位器本身内的锁定机构可以允许单向平移，同时使锚固件能够锁定在缝合线上。这种单向锚定锁定机构有助于锚固件之间的组织褶皱的收紧，并且可以在一个或多个锚固件中使用紧固组织褶皱。

2. 发明授权

US07736378B2 Apparatus and methods for positioning and securing anchors 有权
标题翻译：用于定位和固定锚固件的装置和方法
公开(公告)号：US07736378B2
公开(公告)日：2010-06-15
申请号：US10841245
申请日：2004-05-07
申请人： Tracy D. Maahs , Richard C. Ewers , Jesus Flores , Alexander Khairkhahan , Ruey-Feng Peh , Vahid Saadat , Cang C. Lam
发明人： Tracy D. Maahs , Richard C. Ewers , Jesus Flores , Alexander Khairkhahan , Ruey-Feng Peh , Vahid Saadat , Cang C. Lam
IPC分类号： A61B17/04
CPC分类号： A61B17/08 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/10 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488 , Y10T24/39 , Y10T24/3936
摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This uni-directional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.
摘要翻译：本文公开了用于定位和固定锚固件的装置和方法。锚固件适于被递送并植入到组织中，特别是患者胃肠系统内的组织中。锚固件适于在缝合线上单向滑动，使得组织褶皱可以在锚固件之间束紧。如果锚固件被拉动，推动或沿着缝合线沿相反方向被推动，锚固件本身内的定位器本身内的锁定机构可以允许单向平移，同时使锚固件能够锁定在缝合线上。这种单向锚定锁定机构有助于锚定器之间的组织褶皱收紧，并且可以在一个或多个锚定器中用于收紧组织折叠。

3. 发明授权

US08057511B2 Apparatus and methods for positioning and securing anchors 有权
标题翻译：用于定位和固定锚固件的装置和方法
公开(公告)号：US08057511B2
公开(公告)日：2011-11-15
申请号：US10841411
申请日：2004-05-07
申请人： Jesus Flores , Richard C. Ewers , Tracy D. Maahs , Alex Khairkhahan , Ruey-Feng Peh , Vahid Saadat
发明人： Jesus Flores , Richard C. Ewers , Tracy D. Maahs , Alex Khairkhahan , Ruey-Feng Peh , Vahid Saadat
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B17/00234 , A61B17/0487 , A61B2017/00827 , A61B2017/00867 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0464 , A61B2017/0475 , A61B2017/0477 , A61B2017/0488 , A61B2017/0496 , A61B2017/06028 , A61B2017/06052 , A61B2017/06176 , Y10T24/39 , Y10T24/3969
摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This uni-directional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.
摘要翻译：本文公开了用于定位和固定锚固件的装置和方法。锚固件适于被递送并植入到组织中，特别是患者胃肠系统内的组织中。锚固件适于在缝合线上单向滑动，使得组织褶皱可以在锚固件之间束紧。如果锚固件被拉动，推动或沿着缝合线沿相反方向被推动，锚固件本身内的定位器本身内的锁定机构可以允许单向平移，同时使锚固件能够锁定在缝合线上。这种单向锚定锁定机构有助于锚定器之间的组织褶皱收紧，并且可以在一个或多个锚定器中使用，以收紧组织褶皱。

4. 发明申请

US20050251157A1 Apparatus and methods for positioning and securing anchors 有权
标题翻译：用于定位和固定锚固件的装置和方法
公开(公告)号：US20050251157A1
公开(公告)日：2005-11-10
申请号：US10840950
申请日：2004-05-07
申请人： Vahid Saadat , Tracy Maahs , Richard Ewers , Marvin Elmers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Cang Lam
发明人： Vahid Saadat , Tracy Maahs , Richard Ewers , Marvin Elmers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Cang Lam
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/28 , A61B17/34
CPC分类号： A61B17/08 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/10 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488 , Y10T24/39 , Y10T24/3936
摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This unidirectional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.
摘要翻译：本文公开了用于定位和固定锚固件的装置和方法。锚固件适于被递送并植入到组织中，特别是患者胃肠系统内的组织中。锚固件适于在缝合线上单向滑动，使得组织褶皱可以在锚固件之间束紧。如果锚固件被拉动，推动或沿着缝合线沿相反方向被推动，锚固件本身内的定位器本身内的锁定机构可以允许单向平移，同时使锚固件能够锁定在缝合线上。这种单向锚定锁定机构有助于锚固件之间的组织褶皱的收紧，并且可以在一个或多个锚固件中使用紧固组织褶皱。

5. 发明申请

US20050251207A1 Apparatus and methods for positioning and securing anchors 有权
公开(公告)号：US20050251207A1
公开(公告)日：2005-11-10
申请号：US10841411
申请日：2004-05-07
申请人： Jesus Flores , Richard Ewers , Tracy Maahs , Alex Khairkhahan , Ruey-Feng Peh , Vahid Saadat
发明人： Jesus Flores , Richard Ewers , Tracy Maahs , Alex Khairkhahan , Ruey-Feng Peh , Vahid Saadat
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06
CPC分类号： A61B17/0469 , A61B17/00234 , A61B17/0487 , A61B2017/00827 , A61B2017/00867 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0464 , A61B2017/0475 , A61B2017/0477 , A61B2017/0488 , A61B2017/0496 , A61B2017/06028 , A61B2017/06052 , A61B2017/06176 , Y10T24/39 , Y10T24/3969
摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This uni-directional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.

6. 发明申请

US20050251206A1 Apparatus and methods for positioning and securing anchors 有权
公开(公告)号：US20050251206A1
公开(公告)日：2005-11-10
申请号：US10841245
申请日：2004-05-07
申请人： Tracy Maahs , Richard Ewers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Vahid Saadat , Cang Lam
发明人： Tracy Maahs , Richard Ewers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Vahid Saadat , Cang Lam
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/28 , A61B17/34
CPC分类号： A61B17/08 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/10 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488 , Y10T24/39 , Y10T24/3936
摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This uni-directional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.

7. 发明申请

US20050251205A1 Apparatus and methods for positioning and securing anchors 审中-公开
标题翻译：用于定位和固定锚固件的装置和方法
公开(公告)号：US20050251205A1
公开(公告)日：2005-11-10
申请号：US10840951
申请日：2004-05-07
申请人： Richard Ewers , Tracy Maahs , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Vahid Saadat
发明人： Richard Ewers , Tracy Maahs , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Vahid Saadat
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/28 , A61B17/34
CPC分类号： A61B17/08 , A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/10 , A61B17/29 , A61B2017/00827 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0477 , A61B2017/0488 , A61B2017/0496 , A61B2017/06028 , A61B2017/06052 , A61B2017/06176 , A61B2017/081 , A61B2017/3488 , Y10T24/39 , Y10T24/3936 , Y10T24/3969
摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This uni-directional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.
摘要翻译：本文公开了用于定位和固定锚固件的装置和方法。锚固件适于被递送并植入到组织中，特别是患者胃肠系统内的组织中。锚固件适于在缝合线上单向滑动，使得组织褶皱可以在锚固件之间束紧。如果锚固件被拉动，推动或沿着缝合线沿相反方向被推动，锚固件本身内的定位器本身内的锁定机构可以允许单向平移，同时使锚固件能够锁定在缝合线上。这种单向锚定锁定机构有助于锚定器之间的组织褶皱收紧，并且可以在一个或多个锚定器中使用，以收紧组织褶皱。

8. 发明申请

US20050251159A1 Methods and apparatus for grasping and cinching tissue anchors 审中-公开
标题翻译：抓紧和收紧组织锚的方法和装置
公开(公告)号：US20050251159A1
公开(公告)日：2005-11-10
申请号：US10954665
申请日：2004-09-29
申请人： Richard Ewers , Cang Lam , Jesus Flores , Vahid Saadat
发明人： Richard Ewers , Cang Lam , Jesus Flores , Vahid Saadat
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/28 , A61B17/34
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/22031 , A61B17/29 , A61B2017/00407 , A61B2017/00469 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0443 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0474 , A61B2017/0475 , A61B2017/0477 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/06171 , A61B2017/0649 , A61B2017/081 , A61B2017/3488
摘要： Methods and apparatus for grasping a suture and cinching and/or locking a tissue anchor are provided. In one variation, a tube is provided having a lumen and a resilient member that obstructs the lumen. A grasper may be advanced coaxially through the lumen, such that it reversibly displaces the resilient member and extends beyond the lumen's outlet to engage suture of the tissue anchor. With suture engaged, the grasper may be withdrawn within the tube, such that the resilient member again obstructs the lumen of the tube. Continued retraction of the grasper relative to the tube and anchor may act to cinch the anchor via interaction between a cinching/locking mechanism of the anchor and the obstructing resilient member. In an alternative variation, a snare device is provided comprising a resilient wire loop that coacts with an element of the snare device or of the tissue anchor for grasping and cinching the tissue anchor.
摘要翻译：提供了用于抓住缝合线并且夹紧和/或锁定组织锚的方法和装置。在一个实施例中，提供具有内腔和阻碍内腔的弹性构件的管。夹持器可以同轴地前进穿过内腔，使得其可逆地移位弹性构件并且延伸超过内腔的出口以接合组织锚的缝合线。通过缝合线接合，抓紧器可以在管内被抽出，使得弹性构件再次阻塞管的内腔。抓紧器相对于管和锚的继续缩回可以通过锚固件的紧固/锁定机构和阻塞弹性构件之间的相互作用而起到锚定作用。在替代变型中，提供了一种圈套装置，其包括与圈套装置或组织锚的元件共同作用以用于抓紧和收紧组织锚固件的弹性线环。

9. 发明授权

US08777903B2 Catheter patch applicator assembly 有权
标题翻译：导管贴片器组装
公开(公告)号：US08777903B2
公开(公告)日：2014-07-15
申请号：US12910400
申请日：2010-10-22
申请人： Jesus Flores , Scott Tufts
发明人： Jesus Flores , Scott Tufts
IPC分类号： A61M5/32
CPC分类号： A61M25/02 , A61F13/023 , A61F13/025 , A61M2025/0266 , A61M2025/0273
摘要： In accordance with aspects of the present invention, an applicator assembly suitable for application of a catheter patch about an insertion site of a percutaneous device includes a body having a distal end, a proximal end, and laterally extending right and left side gripping members, a pull tab member attached toward the proximal end of the body, and a release tab connected to the pull tab member, wherein the release tab is positioned toward the distal end of the body so that a lower surface of the release tab abuts an upper surface of the body. The release tab may have a securing mechanism for securing a catheter patch to a lower surface of the body toward the distal end of the body. A method of applying a catheter patch about an insertion site of a percutaneous device using an applicator assembly is provided.
摘要翻译：根据本发明的方面，适于在经皮装置的插入部位附近施加导管贴片的涂抹器组件包括具有远端，近端和横向延伸的左右握持构件的主体，拉片构件附接到主体的近端，以及释放突片，其连接到拉片构件，其中释放舌片朝向身体的远端定位，使得释放舌片的下表面邻接身体。释放突片可以具有用于将导管贴片固定到身体的下表面的固定机构朝向身体的远端。提供了一种使用施用器组件将导管贴片围绕经皮装置的插入部位施加的方法。

10. 发明授权

US07993066B2 Liquid applicator and method for reducing the concentration of by-products from antiseptic 有权
标题翻译：液体涂抹器和减少副产物从防腐剂中浓缩的方法
公开(公告)号：US07993066B2
公开(公告)日：2011-08-09
申请号：US12782140
申请日：2010-05-18
申请人： Jesus Flores , Scott A. Tufts , Angel G. Magallon , James R. Bardwell
发明人： Jesus Flores , Scott A. Tufts , Angel G. Magallon , James R. Bardwell
IPC分类号： B43K5/14
CPC分类号： A61M35/006 , A45D34/04 , A45D2200/1018
摘要： An applicator for reducing the concentration of unwanted chemicals such as para-chloroaniline (PCA) from an antiseptic solution includes an antiseptic solution in amount sufficient to have an antimicrobial effect on a surface and at least one hydrophobic or hydrophilic material. The hydrophobic or hydrophilic material selectively removes undesired by-products from the antiseptic solution when the antiseptic solution contacts the hydrophobic or hydrophilic material. A method for selectively removing unwanted by-products from an antiseptic solution includes the steps of providing an antiseptic solution in amount sufficient to have an antimicrobial effect on a surface and contacting the antiseptic solution with at least one hydrophobic or hydrophilic material that selectively removes the unwanted by-products from the antiseptic solution.
摘要翻译：用于从防腐溶液中降低不需要的化学物质如对氯苯胺（PCA）的浓度的涂布器包括足以对表面具有抗微生物作用的量的抗菌溶液和至少一种疏水或亲水性材料。当防腐溶液接触疏水或亲水材料时，疏水或亲水材料选择性地从防腐溶液中除去不需要的副产物。用于选择性地从防腐溶液中除去不需要的副产物的方法包括以下步骤：提供足以对表面具有抗微生物作用的量的防腐溶液，并使防腐溶液与至少一种疏水或亲水材料接触，所述疏水或亲水材料选择性地除去不需要的来自防腐溶液的副产物。

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