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1. 发明授权

US5561126A 4-oxa-1-azabicyclo [3,2,0] heptan-7-one derivatives as antitumor agents 失效
标题翻译： 4-氧杂-1-氮杂双环[3,2,0]庚-7-酮衍生物作为抗肿瘤剂
公开(公告)号：US5561126A
公开(公告)日：1996-10-01
申请号：US362490
申请日：1995-03-16
申请人： Toshio Otani , Shinji Oie , Hiroshi Matsumoto , Mark Tempest , Ronald Micetich , Rajeshwar Singh , Tomohiro Yamashita
发明人： Toshio Otani , Shinji Oie , Hiroshi Matsumoto , Mark Tempest , Ronald Micetich , Rajeshwar Singh , Tomohiro Yamashita
IPC分类号： C07D503/00 , A61K31/42 , A61P35/00 , H61K31/395
CPC分类号： A61K31/42
摘要： The present invention relates to the use of 4-oxa-1-azabicyclo [3,2,0] heptan-7-one derivatives of formula (I) or a pharmaceutically acceptable salt thereof, as antitumor agents. ##STR1## Wherein R is --OCOR.sub.1 group wherein R.sub.1 is hydrogen atom, a C.sub.1-9 alkyl group which may be substituted by either one or two substituents selected together from halogen atom, hydroxy, carboxy group or (3RS,5SR)-(4-oxo-1-azabicyclo[3,2,0]heptan-7-one-3-yl) methyloxycarbonyl, a C.sub.2-17 alkenyl group, which may be substituted by carboxy group or (3RS,5SR)-(4-oxa-1-azabicyclo [3,2,0]heptan-7-one-3-yl)methyloxycarbonyl, A C.sub.2-4 alkynyl group, a C.sub.3-6 cycloalkyl group which may be substituted by carboxy group or phenyl group which may have 1, 2 or 3 substituents selected from the group consisting of cyano group, halogen atom, C.sub.1-6 alkoxy group which may be substituted by carboxy group, C.sub.1-6 alkyl group, amino group or hydroxy group.--OR.sub.2 wherein R.sub.2 is a hydrogen atom or benzyl group which may be substituted by 1 or 2 C.sub.1-6 alkoxy group.--S(O).sub.n R.sub.3 wherein R.sub.3 is phenyl group or a benzyl group which may be substituted by C.sub.1-6 alkyl group, n is 0, 1, or 2;or --CH.sub.2 OH.
摘要翻译： PCT No.PCT / GB93 / 01435 Sec。 371日期1995年3月16日 102（e）1995年3月16日PCT PCT 1993年7月8日PCT公布。公开号WO94 / 01109 1994年1月20日的日本本发明涉及式（I）的4-氧杂-1-氮杂双环[3,2,0]庚-7-酮衍生物或其药学上可接受的盐作为抗肿瘤剂。（I）其中R是-OCOR1基团，其中R1是氢原子，可以被一个或两个选自卤原子，羟基，羧基或（3RS，5SR）的取代基取代的C1-9烷基， - （4-氧代-1-氮杂双环[3,2,0]庚-7-酮-3-基）甲氧基羰基，可被羧基取代的C 2-7烯基或（3RS，5SR） - （ 4-氧杂-1-氮杂双环[3,2,0]庚-7-酮-3-基）甲氧基羰基，C 2-4炔基，可被羧基或苯基取代的C 3-6环烷基，可以具有1,2或3个选自氰基，卤素原子，可被羧基，C 1-6烷基，氨基或羟基取代的C 1-6烷氧基的取代基。 -OR 2，其中R 2是可被1或2个C 1-6烷氧基取代的氢原子或苄基。 -S（O）n R 3，其中R 3是苯基或可被C 1-6烷基取代的苄基，n是0,1或2; 或-CH 2 OH。

2. 发明授权

US5994342A 3-(substituted methyl)-4-oxa-1-azabicyclo[3.2.0]heptan-7-one derivatives useful as antitumor agents 失效
标题翻译：可用作抗肿瘤剂的3-（取代的甲基）-4-氧杂-1-氮杂双环[3.2.0]庚-7-酮衍生物
公开(公告)号：US5994342A
公开(公告)日：1999-11-30
申请号：US513802
申请日：1997-04-04
申请人： Rajeshwar Singh , Tomohiro Yamashita , Charles Fiakpui , George Thomas , Chan Ha , Hiroshi Matsumoto , Toshio Otani , Shinji Oie , Ronald Micetich
发明人： Rajeshwar Singh , Tomohiro Yamashita , Charles Fiakpui , George Thomas , Chan Ha , Hiroshi Matsumoto , Toshio Otani , Shinji Oie , Ronald Micetich
IPC分类号： A61K31/42 , A61P35/00 , C07D503/00
CPC分类号： C07D503/00 , Y02P20/55
摘要： The present invention is based on the discovery that certain 3-(substituted methyl)-4-oxa-1-azabicyclo[3.2.0]heptan-7-one derivatives of formula I or a pharmaceutically acceptable salt thereof are useful as antitumor agents against sensitive and resistant tumor cells. ##STR1## Wherein X is NH or O, and R is defined in the specification.
摘要翻译： PCT No.PCT / GB95 / 00024 Sec。 371日期：1998年8月5日 102（e）日期1998年8月5日PCT提交1995年1月6日PCT公布。 WO95 / 18807 PCT出版物日期1995年7月13日本发明基于以下发现：式I的某些3-（取代的甲基）-4-氧杂-1-氮杂双环[3.2.0]庚-7-酮衍生物或其药学上可接受的盐是用作抗敏感和抗性肿瘤细胞的抗肿瘤剂。其中X是NH或O，R在本说明书中定义。

3. 发明授权

US5652234A 3-(7-oxo-1-aza-4-oxabicyclo[3.2.0]hept-3-yl)alanine derivative as antitumor agent 失效
标题翻译： 3-（7-氧代-1-氮杂-4-氧杂双环[3.2.0]庚-3-基）丙氨酸衍生物作为抗肿瘤剂
公开(公告)号：US5652234A
公开(公告)日：1997-07-29
申请号：US513803
申请日：1995-10-06
申请人： Rajeshwar Singh , Tomohiro Yamashita , Charles Fiakpui , George Thomas , Chan Ha , Hiroshi Matsumoto , Toshio Otani , Shinji Oie , Ronald Micetich
发明人： Rajeshwar Singh , Tomohiro Yamashita , Charles Fiakpui , George Thomas , Chan Ha , Hiroshi Matsumoto , Toshio Otani , Shinji Oie , Ronald Micetich
IPC分类号： C07D503/00 , A61K31/42 , A61P35/02 , A61K31/395
CPC分类号： A61K31/42
摘要： The present invention relates to the use of 3-(7-oxo-1-aza-4-oxabicyclo[3.2.0]hept-3-yl)alanine derivatives of formula (I) or a pharmaceutically acceptable salt thereof, as antitumor agents. ##STR1## Wherein R is: hydrogen or COOR.sub.2 wherein R.sub.2 is C.sub.1 -C.sub.3 alkyl group which may be substituted with aryl group.Wherein R.sub.1 is:hydrogen or C.sub.1 -C.sub.3 alkyl group which may be substituted with one or two aryl groups.
摘要翻译： PCT No.PCT / GB95 / 00023 Sec。 371日期1995年10月6日 102（e）日期1995年10月6日PCT 1995年1月6日PCT PCT。公开号WO95 / 18611 PCT 日期：1995年7月13日本发明涉及式（I）的3-（7-氧代-1-氮杂-4-氧杂双环[3.2.0]庚-3-基）丙氨酸衍生物或其药学上可接受的盐作为抗肿瘤剂。（I）其中R为：氢或COOR 2，其中R 2为可被芳基取代的C 1 -C 3烷基。其中R1是：可被一个或两个芳基取代的氢或C1-C3烷基。

4. 发明授权

US5698528A Substance IT-62-B and medicinal composition containing the same 失效
标题翻译：物质IT-62-B和含有其的药物组合物
公开(公告)号：US5698528A
公开(公告)日：1997-12-16
申请号：US601023
申请日：1996-02-23
申请人： Takashi Kawauchi , Toru Sasaki , Hiroshi Matsumoto , Toshio Otani , Ru-Xian Chen , Ming-Yu Huang , Ken-ichiro Yoshida
发明人： Takashi Kawauchi , Toru Sasaki , Hiroshi Matsumoto , Toshio Otani , Ru-Xian Chen , Ming-Yu Huang , Ken-ichiro Yoshida
IPC分类号： C07H15/252 , C07H17/00 , C12P19/56 , A61K31/71
CPC分类号： C07H15/252 , C07H17/00 , C12P19/56
摘要： A substance IT-62-B represented by the following formula (1): ##STR1## a production process thereof, a medicinal composition comprising the compound as an active component, and methods of treating an infectious disease caused by bacteria and a tumor, in which such a substance is administered. The compound according to the invention has good antibacterial activities against gram-positive bacteria and some of gram-negative bacteria, and also possesses excellent antitumor activities against tumors such as human nasopharyngeal carcinoma, and is hence useful as a medicine.
摘要翻译： PCT No.PCT / JP95 / 01384。 371日期1996年2月23日 102（e）日期1996年2月23日PCT提交1995年7月12日PCT公布。出版物WO96 / 02659 日期：1996年2月1日由下述式（1）表示的物质IT-62-B：（1）其制备方法，含有作为活性成分的化合物的药物组合物，以及治疗感染性疾病的方法由细菌和肿瘤引起，其中施用这样的物质。根据本发明的化合物对革兰氏阳性细菌和一些革兰氏阴性细菌具有良好的抗菌活性，并且对人类鼻咽癌等肿瘤具有优异的抗肿瘤活性，因此可用作药物。

5. 发明授权

US5585373A 3-(7'-oxo-1'-aza-4'-oxabicyclo[3.2.0]-hept-3'-YL)propionic acid derivative as antitumor agent 失效
标题翻译： 3-（7'-氧代-1'-氮杂-4'-氧杂二环[3.2.0] - 庚-3'-基）丙酸衍生物作为抗肿瘤剂
公开(公告)号：US5585373A
公开(公告)日：1996-12-17
申请号：US341177
申请日：1994-11-18
申请人： Zhang Z. Ping , Zhen J. Sheng , Zhang Q. Rong , Zhang J. Liang , Singh Rajeshwar , Tomohiro Yamashita , Toshiyuki Toko , Hiroshi Matsumoto
发明人： Zhang Z. Ping , Zhen J. Sheng , Zhang Q. Rong , Zhang J. Liang , Singh Rajeshwar , Tomohiro Yamashita , Toshiyuki Toko , Hiroshi Matsumoto
IPC分类号： A61K31/42 , A61P35/00 , B01J23/40 , B01J27/232 , C07D503/00 , C07D503/18 , C07D498/047 , C07D205/08
CPC分类号： C07D503/00 , Y02P20/55
摘要： A derivative of 3-(7'-oxo-1'-aza-4'-oxabicyclo[3.2.0 ]hept-3'-yl)propionic acid represented by the formula ##STR1## wherein R.sub.1 is a hydrogen atom, a lower alkyl group optionally having one or more cycloalkyl groups, a lower acyl group, a benzoyl group optionally having one or more substituents or a benzyl group optionally having one or more substituents, R.sub.2 is a hydrogen atom or a carboxyl-protecting group, R.sub.3 is a hydroxyl group, an azido group, a benzenesulfonyloxy group optionally having one or more substituents, a lower alkylsulfonyloxy group optionally having one or more substituents, a tri-substituted silyloxy group or an amino group optionally having one or more substituents, provided that when R.sub.1 and R.sub.2 are hydrogen atoms, R.sub.3 is not an amino group, and a salt thereof.
摘要翻译：由式（I）表示的3-（7'-氧代-1'-氮杂-4'-氧杂双环[3.2.0]庚-3'-基）丙酸的衍生物，其中R1是氢原子，任选具有一个或多个环烷基的低级烷基，低级酰基，任选具有一个或多个取代基的苯甲酰基或任选具有一个或多个取代基的苄基，R 2是氢原子或羧基保护基， R3是羟基，叠氮基，任选具有一个或多个取代基的苯磺酰氧基，任选具有一个或多个取代基的低级烷基磺酰氧基，三取代的甲硅烷氧基或任选具有一个或多个取代基的氨基，条件是当R 1和R 2是氢原子时，R 3不是氨基，及其盐。

6. 发明授权

US09118874B2 Image capturing device, color measuring device, color measuring system, image forming apparatus, and color measuring method 有权
标题翻译：图像捕获装置，色彩测量装置，色彩测量系统，成像装置和色彩测量方法
公开(公告)号：US09118874B2
公开(公告)日：2015-08-25
申请号：US13800001
申请日：2013-03-13
申请人： Hiroshi Matsumoto , Nobuyuki Satoh , Yasuyuki Suzuki , Mamoru Yorimoto , Masato Kobayashi , Yuichi Sakurada , Suguru Yokozawa , Tatsuhiko Okada , Tomokazu Kanzawa , Daisaku Horikawa
发明人： Hiroshi Matsumoto , Nobuyuki Satoh , Yasuyuki Suzuki , Mamoru Yorimoto , Masato Kobayashi , Yuichi Sakurada , Suguru Yokozawa , Tatsuhiko Okada , Tomokazu Kanzawa , Daisaku Horikawa
IPC分类号： G06F3/12 , G06K15/12 , H04N1/40 , G06T5/00 , H04N1/60 , G01J3/02 , G01J3/46 , G01J3/52
CPC分类号： H04N1/6033 , G01J3/0208 , G01J3/0262 , G01J3/0291 , G01J3/0297 , G01J3/462 , G01J3/52 , G01J3/524 , H04N1/6044
摘要： An image capturing device includes a sensor unit that captures a predetermined range including a subject; a reference chart that is captured by the sensor unit together with the subject; an illumination light source that illuminates the subject and the reference chart; a lens member including one or more lenses arranged in an optical path of reflected light extending from the subject and the reference chart to the sensor unit; and a lens moving unit that moves at least one lens of the lens member so as to change a position thereof in a direction along the optical path.
摘要翻译：图像捕获装置包括：捕获包括被摄体的预定范围的传感器单元; 由传感器单元与被摄体一起捕获的参考图; 照明对象和参考图的照明光源; 透镜构件，包括布置在从被摄体延伸的反射光的光路中的一个或多个透镜和参考图表到传感器单元; 以及透镜移动单元，其移动透镜构件的至少一个透镜，以便沿着光路的方向改变其位置。

7. 发明授权

US09016817B2 Printing apparatus, printing method and computer program product 有权
标题翻译：印刷设备，印刷方法和电脑程序产品
公开(公告)号：US09016817B2
公开(公告)日：2015-04-28
申请号：US13045933
申请日：2011-03-11
申请人： Hiroshi Matsumoto
发明人： Hiroshi Matsumoto
IPC分类号： B41J29/38 , G06K15/10 , G06K15/02
CPC分类号： G06K15/10 , G06K15/1863 , G06K15/1868 , G06K15/1894
摘要： A printing apparatus that is an inkjet printing apparatus includes a print head that includes a plurality of nozzles that eject liquid droplets, and prints output data onto a recording medium in a plurality of scans, a storage unit including number of storage areas, the number being determined based on a scheme of the scans, an intermediate data generating unit that generates intermediate data corresponding to an image to be output in each of the scans of the print head from input image data, an intermediate data storing processing unit that stores the intermediate data in different storage areas of the storage unit corresponding to the respective scans of the print head, and an output data converting unit that converts the intermediate data stored in the storage unit into the output data, and sends the output data to the print head.
摘要翻译：作为喷墨打印装置的打印装置包括：打印头，其包括喷射液滴的多个喷嘴，并且在多个扫描中将输出数据打印到记录介质上;存储单元，包括多个存储区域，数量为基于扫描方案确定的中间数据生成单元，其从输入图像数据生成与在打印头的每次扫描中要输出的图像相对应的中间数据;中间数据存储处理单元，其存储中间数据在对应于打印头的相应扫描的存储单元的不同存储区域中，以及输出数据转换单元，将存储在存储单元中的中间数据转换为输出数据，并将输出数据发送到打印头。

8. 发明申请

US20150070737A1 GLOSSINESS DETERMINING DEVICE, COLOR MEASURING DEVICE, IMAGE FORMING APPARATUS, AND GLOSSINESS DETERMINATION METHOD 有权
标题翻译：光学测量装置，颜色测量装置，图像形成装置和光滑测定方法
公开(公告)号：US20150070737A1
公开(公告)日：2015-03-12
申请号：US14482499
申请日：2014-09-10
申请人： Satoshi Hirata , Nobuyuki Satoh , Yasuyuki Suzuki , Hideaki Suzuki , Satoshi Iwanami , Mamoru Yorimoto , Masayuki Fujii , Masato Kobayashi , Hiroshi Matsumoto
发明人： Satoshi Hirata , Nobuyuki Satoh , Yasuyuki Suzuki , Hideaki Suzuki , Satoshi Iwanami , Mamoru Yorimoto , Masayuki Fujii , Masato Kobayashi , Hiroshi Matsumoto
IPC分类号： H04N1/56 , H04N1/50
CPC分类号： H04N1/6044
摘要： A glossiness determining device includes: a light source; a two-dimensional sensor that receives reflected light containing a specular reflection component of a subject illuminated by the light source, and outputs an image of the subject; and a determining unit that determines glossiness of the subject by using a saturated image, which is the image of the subject output by the two-dimensional sensor and in which pixel values of a partial area are saturated.
摘要翻译：光泽度确定装置包括：光源; 二维传感器，其接收由光源照射的被检体的镜面反射成分的反射光，并输出被检体的图像; 以及确定单元，其通过使用作为由二维传感器输出的被摄体的图像的饱和图像并且部分区域的像素值饱和来确定被摄体的光泽度。

9. 发明授权

US08647283B2 Pulse abnormality detecting device 有权
标题翻译：脉搏异常检测装置
公开(公告)号：US08647283B2
公开(公告)日：2014-02-11
申请号：US12736837
申请日：2008-07-17
申请人： Hiroshi Matsumoto , Kazuko Komatsu
发明人： Hiroshi Matsumoto , Kazuko Komatsu
IPC分类号： A61B5/024
CPC分类号： A61B5/02438 , A61B5/681
摘要： A pulse abnormality detecting device comprises a band attached to a wrist, a first sliding member with which the band is armored and which slides in the circumference direction of the band along the band, a second sliding member which is slidably provided on the first sliding member and which slides in the axis direction of the band, a pulse sensor which is provided on the second sliding member and which is provided in such a manner that the position of the sensor can be adjusted to the inner side or the side of the band, and a pulse abnormality detecting unit for detecting the abnormality of the pulse from the output data of the pulse sensor. The device can accurately detect the pulse of a user with high precision, adapting to a personal difference.
摘要翻译：一种脉冲异常检测装置，包括安装在手腕上的带状物，带状铠装的第一滑动构件，沿着带状物沿带状物的圆周方向滑动的第一滑动构件，可滑动地设置在第一滑动构件上的第二滑动构件并且其在所述带的轴线方向上滑动;脉冲传感器，其设置在所述第二滑动构件上，并且以使得所述传感器的位置能够调节到所述带的内侧或侧面的方式设置; 以及脉冲异常检测单元，用于根据脉冲传感器的输出数据检测脉冲的异常。该设备可以高精度地精确检测用户的脉搏，适应个人差异。

10. 发明授权

US08575532B2 Solid-state imaging device and driving method of solid-state imaging device 失效
标题翻译：固态成像装置及固态成像装置的驱动方法
公开(公告)号：US08575532B2
公开(公告)日：2013-11-05
申请号：US13338727
申请日：2011-12-28
申请人： Hiroshi Matsumoto , Mamoru Iesaka , Sei Suzuki , Katsuya Furukawa
发明人： Hiroshi Matsumoto , Mamoru Iesaka , Sei Suzuki , Katsuya Furukawa
IPC分类号： H01L27/00
CPC分类号： H04N5/3595 , H01L27/14843 , H01L27/14887 , H04N5/37213 , H04N5/3728
摘要： A solid-state imaging device of the present invention is capable of thinning signals for each column. The solid-state imaging device includes: photo diodes, a drain into which charges transferred by first column CCDs are swept-off, and transfer control units each of which is provided to the corresponding first column CCDs, and transfers, to a row CCD and to the drain, the charges transferred by the corresponding first column CCDs. Each of the transfer control units includes: a second column CCD which transfers, in a column direction, the charges transferred by the first column CCDs corresponding to the transfer control unit, and a column CCD terminal gate which is provided between the second column CCD and the row CCD, and forms a potential barrier between the second column CCD and the row CCD.
摘要翻译：本发明的固态成像装置能够使每列的信号变薄。固态成像装置包括：光电二极管，由第一列CCD转移的电荷的漏极，以及各自提供给相应的第一列CCD的转移控制单元，并将其传送到行CCD和到排水管，由相应的第一列CCD转移电荷。每个传送控制单元包括：第二列CCD，其沿列方向传送由与传送控制单元相对应的第一列CCD传送的电荷;以及列CCD端子栅极，其设置在第二列CCD和行CCD，并且在第二列CCD和行CCD之间形成势垒。

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