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1. 发明授权

US5854471A Apparatus using a thermistor with a positive temperature coefficient 失效
标题翻译：使用具有正温度系数的热敏电阻的装置
公开(公告)号：US5854471A
公开(公告)日：1998-12-29
申请号：US835475
申请日：1997-04-08
申请人： Tomoaki Tadokoro , Akira Mizoi , Shinji Omura , Tomomi Okada , Osamu Watanabe
发明人： Tomoaki Tadokoro , Akira Mizoi , Shinji Omura , Tomomi Okada , Osamu Watanabe
IPC分类号： H05B3/14 , H01C7/02 , H01C7/10 , H05B3/06 , F24D13/00 , H05B1/02
CPC分类号： H01C7/10 , F24H3/0429 , F24H9/1872 , H05B3/14 , H05B2203/02
摘要： A PTC (positive temperature coefficient) thermistor heating apparatus includes two or more heating blocks, each heating block including a PTC thermistor and radiating elements disposed in contact with at least two surfaces of the PTC thermistor; an elastic element disposed between the heating blocks; and insulating elements for holding portions of the radiating elements at the ends of the heating blocks; wherein the heating blocks are biased from each other by an elastic force of the elastic element.
摘要翻译： PTC（正温度系数）热敏电阻加热装置包括两个或更多个加热块，每个加热块包括PTC热敏电阻和设置成与PTC热敏电阻的至少两个表面接触的辐射元件; 布置在所述加热块之间的弹性元件; 以及用于保持加热块的端部处的辐射元件的部分的绝缘元件; 其中所述加热块通过所述弹性元件的弹性力彼此偏置。

2. 发明申请

US20100318042A1 ADHESIVE PATCH 有权
标题翻译：胶粘贴
公开(公告)号：US20100318042A1
公开(公告)日：2010-12-16
申请号：US12864183
申请日：2009-01-22
申请人： Tomomi Okada , Shigeo Ohta , Nobuo Tsutsumi
发明人： Tomomi Okada , Shigeo Ohta , Nobuo Tsutsumi
IPC分类号： A61F13/02
CPC分类号： A61K31/618 , A61K9/7053 , A61K9/7076
摘要： Provided is an adhesive patch including a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a woven fabric knitted in stockinette stitch on both sides having two or more rows of crimped polyethylene terephthalate multifilament yarns, the adhesive layer contains 25 to 50% by mass of a liquid organic ingredient and 25 to 50% by mass of a thermoplastic elastomer based on the total mass of the layer and contains 10% by mass or more of methyl salicylate as the liquid organic ingredient based on the total mass of the layer, and the storage elastic modulus (G′) of the adhesive layer is 30000 to 75000 Pa at 10 rad/s and 37° C.
摘要翻译：提供了一种粘合贴片，其包括层叠在支撑体的至少一侧上的可拉伸支撑体和粘合剂层，其中，所述可拉伸支撑体包括编织在两侧具有两排或更多排卷曲聚对苯二甲酸乙二醇酯复丝纱线的织布上，粘合剂层含有25〜50质量％的液体有机成分和25〜50质量％的基于该层的总质量的热塑性弹性体，含有10质量％以上的水杨酸甲酯作为液体有机成分基于该层的总质量，并且粘合剂层的储能弹性模量（G'）在10rad / s和37℃下为30000至75000Pa。

3. 发明授权

US6060485A Arylacetic amide derivative or salt thereof, and pharmaceutical comprising it 失效
标题翻译：芳酰乙酰胺衍生物或其盐，以及包含它的药物
公开(公告)号：US6060485A
公开(公告)日：2000-05-09
申请号：US181091
申请日：1998-10-28
申请人： Terumitsu Kaihoh , Tomomi Okada , Yoshinori Takahashi , Hiroyuki Mizuno , Haruyoshi Honda , Susumu Sato
发明人： Terumitsu Kaihoh , Tomomi Okada , Yoshinori Takahashi , Hiroyuki Mizuno , Haruyoshi Honda , Susumu Sato
IPC分类号： C07D211/58 , C07D211/94 , C07D401/12 , A61K31/445
CPC分类号： C07D401/12 , C07D211/58 , C07D211/94
摘要： Described is an arylacetic amide derivative represented by the following formula (1): ##STR1## wherein R.sup.1 represents an aryl group or the like, R.sup.2 and R.sup.3 each independently represents an alkyl group, a cycloalkyl group or the like, and R.sup.4 represents an aralkyl group, an alkyl group or the like; or salt thereof. The compound according to the present invention has both excellent anticholinergic action and calcium antagonism and at the same time has high selectivity to bladder, so that it is useful as a preventive or remedy for urinary disorders.
摘要翻译：描述了由下式（1）表示的芳基乙酰胺衍生物：其中R 1表示芳基等，R 2和R 3各自独立地表示烷基，环烷基等，R 4表示芳烷基，烷基等; 或其盐。根据本发明的化合物具有优异的抗胆碱能作用和钙拮抗作用，同时对膀胱具有高选择性，因此可用作尿障碍的预防或治疗方法。

4. 发明授权

US6124347A Chromene derivatives and salts thereof, and pharmaceuticals containing the same 失效
标题翻译：色烯衍生物及其盐，以及含有它们的药物
公开(公告)号：US6124347A
公开(公告)日：2000-09-26
申请号：US162451
申请日：1998-09-29
申请人： Fumio Ishii , Haruyoshi Honda , Fujiko Konno , Tomomi Okada , Terumitsu Kaihoh , Yoshihiro Nagao , Susumu Sato , Hideaki Matsuda
发明人： Fumio Ishii , Haruyoshi Honda , Fujiko Konno , Tomomi Okada , Terumitsu Kaihoh , Yoshihiro Nagao , Susumu Sato , Hideaki Matsuda
IPC分类号： A61K31/35 , A61K31/352 , A61P3/08 , A61P3/10 , A61P43/00 , C07D311/58 , C07D311/64 , A61K31/353 , C07D311/60
CPC分类号： C07D311/58
摘要： Disclosed are chromene derivatives represented by the following formula: ##STR1## wherein R.sup.1 s represent alkyl, alkoxy or like groups, R.sup.2 represents a hydrogen atom or an alkyl group, R.sup.3 represents a substituted or unsubstituted phenyl, naphthyl or heterocyclic group, and m stands for an integer of from 0 to 4, and their salts; and pharmaceuticals containing them as effective ingredients. The chromene derivatives and their salts show excellent AGE formation inhibitory action and are useful as preventives and therapeutics for diabetic complications.
摘要翻译：公开了由下式表示的色烯衍生物：其中R 1表示烷基，烷氧基或类似基团，R 2表示氢原子或烷基，R 3表示取代或未取代的苯基，萘基或杂环基，m表示 0至4，及其盐; 和含有它们作为有效成分的药物。色烯衍生物及其盐显示优异的AGE形成抑制作用，并且可用作糖尿病并发症的预防剂和治疗剂。

5. 发明授权

US08382729B2 Adhesive patch 有权
标题翻译：胶贴
公开(公告)号：US08382729B2
公开(公告)日：2013-02-26
申请号：US12864183
申请日：2009-01-22
申请人： Tomomi Okada , Shigeo Ohta , Nobuo Tsutsumi
发明人： Tomomi Okada , Shigeo Ohta , Nobuo Tsutsumi
IPC分类号： A61F13/02
CPC分类号： A61K31/618 , A61K9/7053 , A61K9/7076
摘要： Provided is an adhesive patch including a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a woven fabric knitted in stockinette stitch on both sides having two or more rows of crimped polyethylene terephthalate multifilament yarns, the adhesive layer contains 25 to 50% by mass of a liquid organic ingredient and 25 to 50% by mass of a thermoplastic elastomer based on the total mass of the layer and contains 10% by mass or more of methyl salicylate as the liquid organic ingredient based on the total mass of the layer, and the storage elastic modulus (G′) of the adhesive layer is 30000 to 75000 Pa at 10 rad/s and 37° C.
摘要翻译：提供了一种粘合贴片，其包括层叠在支撑体的至少一侧上的可拉伸支撑体和粘合剂层，其中，所述可拉伸支撑体包括编织在两侧具有两排或更多排卷曲聚对苯二甲酸乙二醇酯复丝纱线的织布上，粘合剂层含有25〜50质量％的液体有机成分和25〜50质量％的基于该层的总质量的热塑性弹性体，含有10质量％以上的水杨酸甲酯作为液体有机成分基于该层的总质量，并且粘合剂层的储能弹性模量（G'）在10rad / s和37℃下为30000至75000Pa。

6. 发明授权

US06174900B1 Substituted piperidine derivative for treating urinary disturbance 失效
标题翻译：用于治疗尿失禁的替代哌啶衍生物
公开(公告)号：US06174900B1
公开(公告)日：2001-01-16
申请号：US09332444
申请日：1999-06-14
申请人： Tomomi Okada , Fujiko Konno , Terumitsu Kaihoh , Masago Ishikawa , Yoshinori Takahashi , Hiroyuki Mizuno , Haruyoshi Honda , Susumu Sato , Hideaki Matsuda
发明人： Tomomi Okada , Fujiko Konno , Terumitsu Kaihoh , Masago Ishikawa , Yoshinori Takahashi , Hiroyuki Mizuno , Haruyoshi Honda , Susumu Sato , Hideaki Matsuda
IPC分类号： A61K31445
CPC分类号： C07D401/12 , C07D211/58 , C07D409/12
摘要： Disclosed herein is a substituted piperidine derivative represented by the following general formula (1): wherein R1 means an aryl or heteroaryl group which may have at least one substituent, R2 denotes an alkyl, alkenyl or aralkyl group, R3 stands for a hydrogen atom or an alkyl group, and R4 is a hydrogen atom, an alkyl group, or an aryl, heteroaryl, aralkyl, aralkenyl or heteroaralkyl group which may have at least one substituent, or a salt thereof. A medicine including this compound is also disclosed. The compound has excellent anticholinergic effect and calcium antagonism and inhibits reflex bladder contraction and is hence useful for prophylaxis of and treatment for a urinary disturbance such as pollakiuria.
摘要翻译：本文公开了由以下通式（1）表示的取代的哌啶衍生物：其中R 1表示可具有至少一个取代基的芳基或杂芳基，R 2表示烷基，烯基或芳烷基，R 3表示氢原子或烷基，可以具有至少一个取代基的芳基，杂芳基，芳烷基，芳烯基或杂芳烷基，或其盐。还公开了包含该化合物的药物。该化合物具有优异的抗胆碱能作用和钙拮抗作用并抑制反射膀胱收缩，因此可用于预防和治疗尿频紊乱如尿频。

7. 发明授权

US5968956A Substituted piperidine derivative and medicine comprising the same 失效
标题翻译：取代的哌啶衍生物及含有它们的药物
公开(公告)号：US5968956A
公开(公告)日：1999-10-19
申请号：US672058
申请日：1996-06-26
申请人： Tomomi Okada , Fujiko Konno , Terumitsu Kaihoh , Masago Ishikawa , Yoshinori Takahashi , Hiroyuki Mizuno , Haruyoshi Honda , Susumu Sato , Hideaki Matsuda
发明人： Tomomi Okada , Fujiko Konno , Terumitsu Kaihoh , Masago Ishikawa , Yoshinori Takahashi , Hiroyuki Mizuno , Haruyoshi Honda , Susumu Sato , Hideaki Matsuda
IPC分类号： C07D211/58 , C07D401/12 , C07D409/12 , A61K31/445 , C07D211/56
CPC分类号： C07D401/12 , C07D211/58 , C07D409/12
摘要： Disclosed herein is a substituted piperidine derivative represented by the following general formula (1): ##STR1## wherein R.sup.1 means an aryl or heteroaryl group which may have at least one substituent, R.sup.2 denotes an alkyl, alkenyl or aralkyl group, R.sup.3 stands for a hydrogen atom or an alkyl group, and R.sup.4 is a hydrogen atom, an alkyl group, or an aryl, heteroaryl, aralkyl, aralkenyl or heteroaralkyl group which may have at least one substituent, or a salt thereof. A medicine including this compound is also disclosed. The compound has excellent anticholinergic effect and calcium antagonism and inhibits reflex bladder contraction and is hence useful for prophylaxis of and treatment for a urinary disturbance such as pollakiuria.
摘要翻译：本文公开了由以下通式（1）表示的取代的哌啶衍生物：其中R 1表示可具有至少一个取代基的芳基或杂芳基，R 2表示烷基，烯基或芳烷基，R 3表示氢原子或烷基，可以具有至少一个取代基的芳基，杂芳基，芳烷基，芳烯基或杂芳烷基，或其盐。还公开了包含该化合物的药物。该化合物具有优异的抗胆碱能作用和钙拮抗作用并抑制反射膀胱收缩，因此可用于预防和治疗尿频紊乱如尿频。

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