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1. 发明申请

US20060110735A1 Use of molecular markers for the preclinical and clinical profiling of inhibitors of enzymes having histone deacetylase activity 审中-公开
标题翻译：分子标记用于具有组蛋白脱乙酰酶活性的酶抑制剂的临床前和临床分析
公开(公告)号：US20060110735A1
公开(公告)日：2006-05-25
申请号：US10528104
申请日：2003-09-18
申请人： Thorsten Heinzel , Oliver Kraemer , Martin Goettlicher , Ping Zhu , Martin Golebiewski , Pier Pelicci , Alexander Maurer , Bernd Hentsch , Saverio Minucci
发明人： Thorsten Heinzel , Oliver Kraemer , Martin Goettlicher , Ping Zhu , Martin Golebiewski , Pier Pelicci , Alexander Maurer , Bernd Hentsch , Saverio Minucci
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： G01N33/6875 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , G01N33/573 , G01N33/574 , G01N2333/70578 , G01N2333/9015 , G01N2333/916 , G01N2500/04
摘要： The present invention relates to the use of molecular markers and related signaling mechanisms for the preclinical and clinical profiling of inhibitors of enzymes having histone deacetylase activity. The invention also relates to the use of such markers as diagnostic and/or prognostic tools for the treatment of tumor patients with such inhibitors.
摘要翻译：本发明涉及分子标记和相关信号传导机制在具有组蛋白脱乙酰酶活性的酶抑制剂的临床前和临床分析中的用途。本发明还涉及这种标记物作为用于治疗具有这种抑制剂的肿瘤患者的诊断和/或预后工具的用途。

2. 发明申请

US20130231472A1 USE OF MOLECULAR MARKERS FOR THE PRECLINICAL PROFILING OF INHIBITORS OF ENZYMES HAVING HISTONE DEACETYLASE ACTIVITY 审中-公开
标题翻译：分子标记用于具有组蛋白脱乙酰酶活性的酶抑制剂的前列腺素的使用
公开(公告)号：US20130231472A1
公开(公告)日：2013-09-05
申请号：US13447797
申请日：2012-04-16
申请人： Thorsten HEINZEL , Oliver H. Kraemer , Martin Goettlicher , Ping Zhu , Martin Golebiewski , Pier Giuseppe Pelicci , Alexander B. Maurer , Bernd Hentsch , Saverio Minucci
发明人： Thorsten HEINZEL , Oliver H. Kraemer , Martin Goettlicher , Ping Zhu , Martin Golebiewski , Pier Giuseppe Pelicci , Alexander B. Maurer , Bernd Hentsch , Saverio Minucci
IPC分类号： G01N33/68 , C12Q1/68
CPC分类号： G01N33/6875 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , G01N33/573 , G01N33/574 , G01N2333/70578 , G01N2333/9015 , G01N2333/916 , G01N2500/04
摘要： The present invention relates to the use of molecular markers and related signaling mechanisms for the preclinical and clinical profiling of inhibitors of enzymes having histone deacetylase activity. The invention also relates to the use of such markers as diagnostic and/or prognostic tools for the treatment of tumor patients with such inhibitors.
摘要翻译：本发明涉及分子标记和相关信号传导机制在具有组蛋白脱乙酰酶活性的酶抑制剂的临床前和临床分析中的用途。本发明还涉及这种标记物作为用于治疗具有这种抑制剂的肿瘤患者的诊断和/或预后工具的用途。

3. 发明授权

US08293718B2 Organic compositions to treat HSF1-related diseases 有权
标题翻译：治疗HSF1相关疾病的有机组合物
公开(公告)号：US08293718B2
公开(公告)日：2012-10-23
申请号：US12970268
申请日：2010-12-16
申请人： Gregory Hinkle , Satyanarayana Kuchimanchi , Stuart Milstein , Markus Warmuth , Wenlai Zhou , Ping Zhu , Tracy S. Zimmermann
发明人： Gregory Hinkle , Satyanarayana Kuchimanchi , Stuart Milstein , Markus Warmuth , Wenlai Zhou , Ping Zhu , Tracy S. Zimmermann
IPC分类号： C12N15/11
CPC分类号： C12N15/113 , A61K31/713 , A61K45/06 , C07H21/02 , C12N2310/14 , C12N2310/321 , C12N2310/322 , C12N2320/31 , C12N2320/51 , C12N2320/53 , Y02A50/467 , C12N2310/3521
摘要： The present disclosure relates to methods of treating heat shock factor 1 (HSF1)-related diseases such as cancer and viral diseases, using a therapeutically effective amount of a RNAi agent to HSF.
摘要翻译：本公开涉及使用治疗有效量的RNAi剂对HSF治疗热休克因子1（HSF1）相关疾病如癌症和病毒性疾病的方法。

4. 发明申请

US20050249293A1 Noise filter for video processing 失效
标题翻译：用于视频处理的噪声滤波器
公开(公告)号：US20050249293A1
公开(公告)日：2005-11-10
申请号：US10959333
申请日：2004-10-05
申请人： Weimin Zeng , Li Alpha , Ping Zhu
发明人： Weimin Zeng , Li Alpha , Ping Zhu
IPC分类号： H04N5/21 , H04N7/26 , H04N5/217
CPC分类号： H04N5/21 , H04N19/117 , H04N19/14
摘要： A noise filter for a video processing system includes a block selector, a cost calculator, a cost table, a cost comparator, and a coefficient filter. The block selector is coupled to receive data from the quantization unit and selects blocks for additional filtering. The selected blocks are provided to the cost calculator determines a cost for each of the coefficients in the block using the cost table and the costs are summed. The cost comparator compares the total to a threshold, and filters the coefficients using the coefficient filter if the total is greater a preset threshold. The noise filter to the VLC unit then outputs the filter data.
摘要翻译：用于视频处理系统的噪声滤波器包括块选择器，成本计算器，成本表，成本比较器和系数滤波器。块选择器被耦合以从量化单元接收数据并且选择用于额外滤波的块。所选择的块被提供给成本计算器使用成本表确定块中的每个系数的成本，并且将成本相加。成本比较器将总和比较为阈值，并且如果总数大于预设阈值，则使用系数滤波器对系数进行滤波。然后，VLC单元的噪声滤波器输出滤波器数据。

5. 发明申请

US20050249292A1 System and method for enhancing the performance of variable length coding 审中-公开
标题翻译：用于增强可变长度编码性能的系统和方法
公开(公告)号：US20050249292A1
公开(公告)日：2005-11-10
申请号：US11065637
申请日：2005-02-23
申请人： Ping Zhu
发明人： Ping Zhu
IPC分类号： H04N7/12
CPC分类号： H04N19/1887 , H04N19/436 , H04N19/61 , H04N19/91 , H04N19/93
摘要： Video data compression requires several calculations to be made repeatedly on pixel data from the video. Some of those calculations are used to determine which way to encode portions of the video data, either to provide the best compression results or simply to comply with the MPEG specification. The present invention presents a set of calculations and logic that can be performed in parallel so that the delay is minimized in order to speed up the compression of digital video data. The present invention provides a third escape mode for use when in performing variable length coding.
摘要翻译：视频数据压缩需要对来自视频的像素数据重复进行多次计算。其中一些计算用于确定编码视频数据部分的方式，以提供最佳压缩结果或简单地符合MPEG规范。本发明提出了可以并行执行的一组计算和逻辑，使得延迟最小化以便加速数字视频数据的压缩。本发明提供了在执行可变长度编码时使用的第三逃逸模式。

6. 发明授权

US09009710B2 Detecting deadlocked file transfer protocol upload connections and performing session self-recovery using information stored in a FIFO resource array 有权
标题翻译：检测死锁文件传输协议上传连接并使用存储在FIFO资源阵列中的信息执行会话自恢复
公开(公告)号：US09009710B2
公开(公告)日：2015-04-14
申请号：US13258312
申请日：2010-05-25
申请人： Xingfeng Xie , Sujian Liu , Hua Chen , Ping Zhu
发明人： Xingfeng Xie , Sujian Liu , Hua Chen , Ping Zhu
IPC分类号： G06F11/00 , G06F11/07 , G06F11/30 , H04L12/26 , H04L29/08 , H04L29/14 , H04L29/06
CPC分类号： H04L67/06 , G06F11/07 , H04L43/00 , H04L43/08 , H04L43/0811 , H04L65/1066 , H04L67/00 , H04L69/40
摘要： A method and a device for file transfer protocol (FTP) deadlock detection and self recovery are provided by the disclosure in order to solve the sudden deadlock problem in the FTP upload task. The method includes: if a daemon determines that a deadlock occurs in an FTP upload task by a heartbeat detection mechanism, the socket resources used by the FTP upload task is recorded at the storage location in a socket resource cycle queue, and a process of ending the FTP upload task is started; determining whether the socket resource cycle queue is full, if it is not full, the socket resources used by the FTP upload task in the current deadlock is put into the socket resource cycle queue, otherwise, the earliest socket resources in the socket resource cycle queue are released, and the socket resources used by the FTP upload task in the current deadlock is put into the socket resource cycle queue.
摘要翻译：本文提供了一种文件传输协议（FTP）死锁检测和自恢复的方法和装置，以解决FTP上传任务中突然的死锁问题。该方法包括：如果守护程序通过心跳检测机制确定FTP上传任务中发生死锁，则FTP上传任务使用的套接字资源将记录在套接字资源周期队列中的存储位置，并且结束 FTP上传任务启动; 确定套接字资源周期队列是否满，如果未满，则将FTP当前死锁中的FTP上传任务使用的套接字资源放入套接字资源周期队列中，否则，套接字资源周期队列中的最早套接字资源被释放，并且当前死锁中的FTP上传任务使用的套接字资源被放入套接字资源周期队列中。

7. 发明申请

US20110119830A1 GAP PROTECTION DEVICE FOR EXAMINING TABLE 有权
标题翻译：用于检查表的防护装置
公开(公告)号：US20110119830A1
公开(公告)日：2011-05-26
申请号：US12953156
申请日：2010-11-23
申请人： Hong Shang , Ning Tao Yang , Xiang Zhang , Ping Zhu
发明人： Hong Shang , Ning Tao Yang , Xiang Zhang , Ping Zhu
IPC分类号： A61G13/00
CPC分类号： A61B5/0555 , A61B6/0407 , G01R33/288
摘要： A gap protection device for an examining table includes a guide rail, a protecting chain and a rigid rope. The guide rail is fixed onto the non-moving part of the examining table. One end of the protecting chain is fixed onto the body of the examining table and is movable along the guide rail so as to cover the gap between the body and the non-moving part of the examining table. The two ends of the rigid rope are respectively connected to the two ends of the protecting chain. When the examining table is moved, the closed loop formed by the protecting chain and the rigid rope circulates synchronously under the drive of the examining table, such that the protecting chain covers the gap between the body and the non-moving part of the examining table.
摘要翻译：用于检查台的间隙保护装置包括导轨，保护链和刚性绳索。导轨固定在检查台的不动部分上。保护链的一端固定在检查台的主体上，并可沿导轨移动，以覆盖主体与检查台的不动部分之间的间隙。刚性绳索的两端分别连接到保护链的两端。当检查台移动时，由保护链和刚性绳形成的闭环在检查台的驱动下同步地循环，使得保护链覆盖主体与检查台的不移动部分之间的间隙。

8. 发明申请

US20100156601A1 LLRP-Based Flexible Reader System And Method 审中-公开
标题翻译：基于LLRP的灵活阅读器系统和方法
公开(公告)号：US20100156601A1
公开(公告)日：2010-06-24
申请号：US12341607
申请日：2008-12-22
申请人： Lang LIN , Hugo Molina , Ping Zhu
发明人： Lang LIN , Hugo Molina , Ping Zhu
IPC分类号： H04Q5/22
CPC分类号： H04L67/12 , H04L67/28
摘要： A system includes a host computing device, a first RFID transceiver, and at least one second RFID transceiver. The host computing device executes an application according to a predetermined RFID communication protocol. The predetermined RFID communication protocol supports communication only with a single RFID transceiver. The first RFID transceiver communicates with the host computing device according to the predetermined RFID communication protocol. The at least one second RFID transceiver communicates with the first RFID transceiver. The at least one second RFID transceiver provides data to the host computing device only via the first RFID transceiver.
摘要翻译：一种系统包括主计算设备，第一RFID收发器和至少一个第二RFID收发器。主计算设备根据预定的RFID通信协议执行应用。预定的RFID通信协议仅支持与单个RFID收发器的通信。第一RFID收发器根据预定的RFID通信协议与主机计算设备进行通信。所述至少一个第二RFID收发器与所述第一RFID收发器通信。至少一个第二RFID收发器仅通过第一RFID收发器向主计算设备提供数据。

9. 发明申请

US20050228970A1 PROCESSING UNIT WITH CROSS-COUPLED ALUS/ACCUMULATORS AND INPUT DATA FEEDBACK STRUCTURE INCLUDING CONSTANT GENERATOR AND BYPASS TO REDUCE MEMORY CONTENTION 失效
标题翻译：具有交叉耦合ALUS /累加器的加工单元和输入数据反馈结构，包括恒定发电机和旁路以减少存储器内容
公开(公告)号：US20050228970A1
公开(公告)日：2005-10-13
申请号：US10209109
申请日：2002-07-30
申请人： Shuhua Xiang , Li Sha , Ping Zhu , Hongjun Yuan , Wei Ni
发明人： Shuhua Xiang , Li Sha , Ping Zhu , Hongjun Yuan , Wei Ni
IPC分类号： G06F7/57 , G06F9/38 , G06F15/00
CPC分类号： G06F9/3867 , G06F7/57 , G06F9/3824 , G06F9/3826 , G06F9/3885
摘要： A processing system includes an arithmetic logic unit (ALU) sub-system that allows data associated with a prior instruction to be preserved for use with a next instruction or subsequent instruction without having to reload the value using an intermediate register. The ALU sub-system includes a pair of ALUs communicatively cross-coupled with a pair of accumulators. The processing system also includes a data selector coupled to the ALU sub-system for use with memory contention prediction. The data selector includes a constant generator that controls storage of data associated with a previous instruction in a bypass element, and a selector to choose between data from a databus element and data stored in the bypass element.
摘要翻译：处理系统包括算术逻辑单元（ALU）子系统，其允许与先前指令相关联的数据被保留以用于下一个指令或后续指令，而不必使用中间寄存器重新加载该值。 ALU子系统包括与一对蓄能器通信地交叉耦合的一对ALU。处理系统还包括耦合到ALU子系统以与存储器争用预测一起使用的数据选择器。数据选择器包括恒定发生器，其控制与旁路元件中的先前指令相关联的数据的存储，以及选择器，用于在数据总线元件的数据和存储在旁路元件中的数据之间进行选择。

10. 发明授权

US06379918B1 Composition, formulae, devices and methods for control of specificity and inclusivity of microorganisms containing closely related antigen epitopes 有权
公开(公告)号：US06379918B1
公开(公告)日：2002-04-30
申请号：US09374560
申请日：1999-08-13
申请人： Philip T. Feldsine , David E. Kerr , Ping Zhu , Linda Mui
发明人： Philip T. Feldsine , David E. Kerr , Ping Zhu , Linda Mui
IPC分类号： C12Q104
CPC分类号： G01N33/56922 , C12Q1/04 , C12Q1/045 , G01N33/56916 , G01N2333/205 , G01N2333/245 , G01N2333/255
摘要： Compositions, formulae, devices and methods for the detection of target microorganisms, such as by visual immunoprecipitate assay, enzyme linked immunoassay, chemiluminescence, immunoblotting, or similar detection technology, wherein detection requires the discrimination among closely related genera, species and strains of antigenically related microorganisms based on immunological reactivity of a highly conserved antigen epitopes with a reagent system comprised of an antibody linked to a detecting reagent. The invention permits a detectable event to occur by exposing inaccessible but highly conserved and specific antigen epitopes to the detecting reagent. Exposure of such antigen epitopes without inactivating microbial metabolism allows for specific detection.

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