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1. 发明申请

US20100278398A1 METHOD AND SYSTEM FOR ASSIGNING A CONFIDENCE METRIC FOR AUTOMATED DETERMINATION OF OPTIC DISC LOCATION 有权
标题翻译：用于自动确定光盘位置的置信度的方法和系统
公开(公告)号：US20100278398A1
公开(公告)日：2010-11-04
申请号：US12263876
申请日：2008-11-03
申请人： Thomas P. Karnowski , Kenneth W. Tobin, JR. , Vijaya Priya Muthusamy Govindasamy
发明人： Thomas P. Karnowski , Kenneth W. Tobin, JR. , Vijaya Priya Muthusamy Govindasamy
IPC分类号： G06K9/00
CPC分类号： G06K9/0061 , G06F19/00 , G06F19/321 , G06T7/0012 , G06T7/70 , G06T2207/30041 , G16H50/20
摘要： A method for assigning a confidence metric for automated determination of optic disc location that includes analyzing a retinal image and determining at least two sets of coordinates locating an optic disc in the retinal image. The sets of coordinates can be determined using first and second image analysis techniques that are different from one another. An accuracy parameter can be calculated and compared to a primary risk cut-off value. A high confidence level can be assigned to the retinal image if the accuracy parameter is less than the primary risk cut-off value and a low confidence level can be assigned to the retinal image if the accuracy parameter is greater than the primary risk cut-off value. The primary risk cut-off value being selected to represent an acceptable risk of misdiagnosis of a disease having retinal manifestations by the automated technique.
摘要翻译：一种用于分配用于自动确定视盘位置的置信度量的方法，包括分析视网膜图像并且确定定位视网膜图像中的视盘的至少两组坐标。可以使用彼此不同的第一和第二图像分析技术来确定坐标集合。可以计算精度参数并将其与主要风险截止值进行比较。如果精度参数小于主要风险截止值，则可以将高置信度分配给视网膜图像，如果精度参数大于主要风险截止值，则可将低置信度水平分配给视网膜图像值。选择主要风险截止值以通过自动化技术代表具有视网膜表现的疾病的误诊的可接受风险。

2. 发明申请

US20110079725A1 APPARATUS AND METHOD TO ACHIEVE HIGH-RESOLUTION MICROSCOPY WITH NON-DIFFRACTING OR REFRACTING RADIATION 有权
标题翻译：用非衍射或者折射辐射实现高分辨率显微镜的装置和方法
公开(公告)号：US20110079725A1
公开(公告)日：2011-04-07
申请号：US12572536
申请日：2009-10-02
申请人： Kenneth W. Tobin, JR. , Philip R. Bingham , Ayman I. Hawari
发明人： Kenneth W. Tobin, JR. , Philip R. Bingham , Ayman I. Hawari
IPC分类号： G01T1/161
CPC分类号： G01T1/295
摘要： An imaging system employing a coded aperture mask having multiple pinholes is provided. The coded aperture mask is placed at a radiation source to pass the radiation through. The radiation impinges on, and passes through an object, which alters the radiation by absorption and/or scattering. Upon passing through the object, the radiation is detected at a detector plane to form an encoded image, which includes information on the absorption and/or scattering caused by the material and structural attributes of the object. The encoded image is decoded to provide a reconstructed image of the object. Because the coded aperture mask includes multiple pinholes, the radiation intensity is greater than a comparable system employing a single pinhole, thereby enabling a higher resolution. Further, the decoding of the encoded image can be performed to generate multiple images of the object at different distances from the detector plane. Methods and programs for operating the imaging system are also disclosed.
摘要翻译：提供了采用具有多个针孔的编码孔径掩模的成像系统。编码的孔径掩模放置在辐射源处以使辐射通过。辐射照射并穿过物体，其通过吸收和/或散射来改变辐射。当通过物体时，在检测器平面处检测辐射以形成编码图像，其包括关于物质的材料和结构属性引起的吸收和/或散射的信息。编码图像被解码以提供对象的重建图像。由于编码孔径掩模包括多个针孔，因此辐射强度大于采用单个针孔的可比系统，从而能够实现更高的分辨率。此外，可以执行编码图像的解码以在与检测器平面不同的距离处产生对象的多个图像。还公开了用于操作成像系统的方法和程序。

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