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1. 发明授权

US5224939A Self locking guide catheter 失效
标题翻译：自锁导向导管
公开(公告)号：US5224939A
公开(公告)日：1993-07-06
申请号：US888748
申请日：1992-05-22
申请人： Thomas J. Holman , Henry J. Pepin , William H. Penny
发明人： Thomas J. Holman , Henry J. Pepin , William H. Penny
IPC分类号： A61M5/158 , A61M25/00 , A61M25/088
CPC分类号： A61M5/158 , A61M25/0014 , A61M2025/0098 , A61M25/0097
摘要： A guide catheter in which the components of the hub include a ratchet mechanism that is operative to lock the hub components together and compress an integral flange of the catheter shaft therebetween to form a seal between the hub and catheter shaft without the use of bonding agents that will not become loosened accidently or inadvertently.
摘要翻译：一种引导导管，其中所述轮毂的部件包括棘轮机构，所述棘轮机构可操作以将所述轮毂部件锁定在一起并将所述导管轴的整体凸缘压缩在其间，以在所述轮毂和导管轴之间形成密封，而不使用粘结剂不会意外或不经意地松动。

2. 发明授权

US5318533A Balloon catheter inflation device including apparatus for monitoring and wireless transmission of inflation data, and system 失效
标题翻译：球囊导管充气装置，包括用于监测和无线传输通气数据的装置，以及系统
公开(公告)号：US5318533A
公开(公告)日：1994-06-07
申请号：US839628
申请日：1992-02-21
申请人： Daniel O. Adams , David J. Haskvitz , Thomas J. Holman , William H. Penny , David J. Serdar , John M. Yates
发明人： Daniel O. Adams , David J. Haskvitz , Thomas J. Holman , William H. Penny , David J. Serdar , John M. Yates
IPC分类号： A61F2/958 , A61M29/00 , A61M5/00
CPC分类号： A61M25/10184 , A61M25/1018 , A61M25/10182 , A61M25/104 , A61M2205/50 , Y10S128/903
摘要： An inflation device includes a syringe forming a cylindrical chamber containing a plunger carrying a stopper or piston arrangement. The chamber is designed to contain an inflation fluid and is in fluid communication with the lumen of a balloon catheter. Movement of the plunger within the chamber will increase or decrease the pressure of the fluid within the chamber and lumen, thereby inflating or deflating the balloon at the distal end of the catheter. A pressure sensor is mounted to the housing in fluid communication with the lumen and is electrically connected to a battery-operated transmitter. The transmitter broadcasts signals representing pressure within the lumen and balloon to a remote receiver. The receiver includes a microprocessor containing a clock and operable to display time and pressure data. A flexible insulator strip is interposed between the battery and the transmitter circuit to prevent operation of the transmitter until desired by the cardiologist. The housing of the inflation device may be opened to remove the batteries for separate disposal and to render the circuit inoperative to prevent reuse. A look-up table associated with the microprocessor permits display of balloon diameter during the procedure.
摘要翻译：膨胀装置包括一个注射器，该注射器形成一个圆筒形腔室，该圆柱形腔室包含一个承载塞子或腔室被设计成容纳充气流体并且与球囊导管的内腔流体连通。柱塞在腔室内的运动将增加或减小腔室和腔内的流体的压力，从而在导管的远端处膨胀或放气气囊。压力传感器安装到外壳上，与腔体流体连通，并与电池供电的变送器电连接。发射机将表示内腔和气球内的压力的信号广播到远程接收器。接收机包括一个包含时钟并可操作以显示时间和压力数据的微处理器。在电池和发射器电路之间插入柔性绝缘体条，以防止发射器的操作，直到心脏病专家期望。可以打开充气装置的壳体以移除电池以进行单独处理，并使电路不起作用以防再次使用。与微处理器相关联的查找表允许在该过程期间显示气球直径。

3. 发明授权

US08795348B2 Medical devices and related methods 有权
标题翻译：医疗器械及相关方法
公开(公告)号：US08795348B2
公开(公告)日：2014-08-05
申请号：US11152555
申请日：2005-06-14
申请人： Jan Weber , Thomas J. Holman , Scott Schewe
发明人： Jan Weber , Thomas J. Holman , Scott Schewe
IPC分类号： A61F2/06 , A61M29/00
CPC分类号： A61F2/95 , A61F2/91 , A61F2/958 , A61F2210/0033 , A61F2220/005 , A61F2220/0058 , A61F2250/0018 , A61F2250/0068 , A61M25/09 , A61M25/1006 , A61M25/10186 , A61M2025/1015 , A61M2025/105 , A61M2025/1056 , A61M2025/1068 , A61M2025/1086 , A61M2025/1093
摘要： A medical system including an elongate member and an elongate element associated with the elongate member so that a shape of the elongate member can be altered upon applying energy to the element.
摘要翻译：一种医疗系统，包括细长构件和与细长构件相关联的细长元件，使得在向元件施加能量时可以改变细长构件的形状。

4. 发明申请

US20120197380A1 Medical Devices and Related Methods 有权
标题翻译：医疗器械及相关方法
公开(公告)号：US20120197380A1
公开(公告)日：2012-08-02
申请号：US13441664
申请日：2012-04-06
申请人： Thomas J. Holman , James Lee Shippy, III , Afsar Ali
发明人： Thomas J. Holman , James Lee Shippy, III , Afsar Ali
IPC分类号： A61F2/84 , A61L29/16 , A61M25/10
CPC分类号： A61M25/1002 , A61F2/958 , A61L29/16 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1088
摘要： This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon.
摘要翻译：本公开涉及医疗装置和相关方法。在一些实施例中，所述方法包括将材料施加到球囊，然后从气囊的一个或多个区域移除材料。

5. 发明申请

US20110054394A1 BONDING SLEEVE FOR A MEDICAL DEVICE 有权
标题翻译：用于医疗设备的连接套管
公开(公告)号：US20110054394A1
公开(公告)日：2011-03-03
申请号：US12872882
申请日：2010-08-31
申请人： Matthew C. Heidner , Thomas J. Holman
发明人： Matthew C. Heidner , Thomas J. Holman
IPC分类号： A61M29/00 , B29C65/02
CPC分类号： A61F2/958 , A61F2002/9583
摘要： A medical device delivery system comprises an inner tube, a medical device disposed about a portion of the distal region of the inner tube, a medical device sheath disposed about the medical device, a medical device sheath retraction device extending proximally from the medical device sheath and an outer sheath disposed about a portion of the medical device sheath retraction device. The distal end of the outer sheath terminates at least one medical device length proximal of the medical device. The medical device sheath is movable relative to the outer sheath and relative to the inner tube.
摘要翻译：医疗装置输送系统包括内管，围绕内管的远端区域的一部分设置的医疗装置，围绕医疗装置设置的医疗装置护套，从医疗装置护套向近侧延伸的医疗装置护套收回装置，设置在所述医疗装置鞘缩回装置的一部分周围的外护套。外护套的远端终止医疗装置近端的至少一个医疗装置长度。医疗器械护套可相对于外护套和相对于内管移动。

6. 发明授权

US07691082B2 Medical devices 有权
标题翻译：医疗设备
公开(公告)号：US07691082B2
公开(公告)日：2010-04-06
申请号：US11174258
申请日：2005-07-01
申请人： James Lee Shippy, III , Thomas J. Holman
发明人： James Lee Shippy, III , Thomas J. Holman
IPC分类号： A61M31/00
CPC分类号： A61M25/1002 , A61M25/1029 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1075 , A61M2025/1086 , Y10T428/139
摘要： Medical devices, for example, those that have balloons, and methods of making the devices are described. For example, in some embodiments, a medical device includes an elongated shaft, and an inflatable balloon carried by the shaft. The balloon includes a first recessed channel, a second recessed channel, a third recessed channel, and a fourth recessed channel, wherein the first recessed channel is spaced from the second recessed channel by a first distance, the third recessed channel is spaced from the fourth recessed channel by the first distance, and the second recessed channel is spaced from the third recessed channel by a second distance different than the first distance.
摘要翻译：描述了医疗设备，例如具有气球的设备，以及制造设备的方法。例如，在一些实施例中，医疗装置包括细长轴和由轴承载的可膨胀气囊。气球包括第一凹槽，第二凹槽，第三凹槽和第四凹槽，其中第一凹槽与第二凹槽相隔第一距离，第三凹槽与第四凹槽相隔，并且所述第二凹陷通道与所述第三凹陷通道间隔不同于所述第一距离的第二距离。

7. 发明申请

US20090125786A1 Mechanism for Adjacent-Symbol Error Correction and Detection 有权
标题翻译：相邻符号误差校正和检测机制
公开(公告)号：US20090125786A1
公开(公告)日：2009-05-14
申请号：US12354037
申请日：2009-01-15
申请人： James W. Alexander , Thomas J. Holman , Mark A. Heap , Stanley S. Kulick
发明人： James W. Alexander , Thomas J. Holman , Mark A. Heap , Stanley S. Kulick
IPC分类号： G11C29/04 , G06F11/07 , G06F11/22
CPC分类号： G11C29/42 , G11C11/401 , G11C2029/0409
摘要： According to one embodiment a computer system is disclosed. The computer system includes memory. The memory includes two or more rows, where each row has a plurality of memory devices. The computer system also includes a chipset. The chipset includes a detection/correction circuit to detect single and double symbol errors and correct single symbol errors for each memory row, and markers to maintain a log of errors within each memory row.
摘要翻译：根据一个实施例，公开了一种计算机系统。计算机系统包括内存。存储器包括两行或更多行，其中每行具有多个存储器件。计算机系统还包括芯片组。该芯片组包括一个检测/校正电路，用于检测单个和双重符号错误，并纠正每个存储器行的单个符号错误，以及标记以维护每个存储器行内的错误日志。

8. 发明授权

US07491188B2 Reinforced and drug-eluting balloon catheters and methods for making same 有权
标题翻译：加强和药物洗脱球囊导管及其制作方法
公开(公告)号：US07491188B2
公开(公告)日：2009-02-17
申请号：US10963272
申请日：2004-10-12
申请人： Thomas J. Holman , Jan Weber , Scott Schewe
发明人： Thomas J. Holman , Jan Weber , Scott Schewe
IPC分类号： A61M29/00
CPC分类号： A61M25/1029 , A61M25/10 , A61M25/1002 , A61M25/1034 , A61M25/1038 , A61M2025/0058 , A61M2025/1031 , A61M2025/105 , A61M2025/1084
摘要： The present invention generally relates to the field of intravascular medical devices, and more specifically to the field of balloon catheters and other similar diagnostic or therapeutic catheters within the body for treatment and diagnosis of diseases. In particular, the present invention relates to reinforced balloon catheters and drug-eluting balloon catheters and corresponding methods for producing same.
摘要翻译：本发明一般涉及血管内医疗装置的领域，更具体地涉及用于治疗和诊断疾病的体内气囊导管和其它类似的诊断或治疗导管领域。特别地，本发明涉及增强气囊导管和药物洗脱球囊导管及其相应的制造方法。

9. 发明申请

US20080114331A1 Medical devices and related methods 有权
标题翻译：医疗器械及相关方法
公开(公告)号：US20080114331A1
公开(公告)日：2008-05-15
申请号：US11599052
申请日：2006-11-14
申请人： Thomas J. Holman , James Lee Shippy , Afsar Ali
发明人： Thomas J. Holman , James Lee Shippy , Afsar Ali
IPC分类号： A61M25/10
CPC分类号： A61M25/1002 , A61F2/958 , A61L29/16 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1088
摘要： This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon.
摘要翻译：本公开涉及医疗装置和相关方法。在一些实施例中，所述方法包括将材料施加到球囊，然后从气囊的一个或多个区域移除材料。

10. 发明授权

US07264458B2 Process and apparatus for forming medical device balloons 有权
标题翻译：用于形成医疗装置气囊的方法和装置
公开(公告)号：US07264458B2
公开(公告)日：2007-09-04
申请号：US10753043
申请日：2004-01-07
申请人： Thomas J. Holman , Nam H. Hoang , Jeffrey S. Lindquist , Richard Dunn , Scott Schewe , Kevin Silberg , David Parsons , Ken Xiao Kang Zhang , Afsar Ali
发明人： Thomas J. Holman , Nam H. Hoang , Jeffrey S. Lindquist , Richard Dunn , Scott Schewe , Kevin Silberg , David Parsons , Ken Xiao Kang Zhang , Afsar Ali
IPC分类号： B29C49/64
CPC分类号： A61M25/1029 , B29C49/6445 , B29L2031/7542
摘要： Medical device balloons are formed from a tubular parison by a process or apparatus which establishes a controlled location (initiation zone) on the parison where radial expansion is initiated. Initiation within the initiation zone is achieved by heating the parison in that location to a higher temperature than the remainder of the parison for at least a portion of the blowing time. A variety of apparatus configurations are provided, some of which allow for the size and location of the initiation zone to be readily reconfigured. Balloons can also be modified, post-blowing, using heating apparatus and methods described.
摘要翻译：医疗装置气囊由管状型坯通过工艺或装置形成，该方法或装置在径向膨胀开始的型坯上建立受控的位置（起始区）。在起始区域内的起始是通过将该位置的型坯加热到比型坯的其余部分高的至少一部分吹制时间的温度来实现的。提供了各种装置配置，其中一些允许容易重新配置启动区域的大小和位置。气球也可以改装，后吹，使用加热装置和方法描述。

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