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1. 发明申请

US20090317294A1 Method of low-temperature dry sterilization and apparatus therefor 审中-公开
标题翻译：低温干燥灭菌方法及其设备
公开(公告)号：US20090317294A1
公开(公告)日：2009-12-24
申请号：US11990975
申请日：2005-08-25
申请人： Takehiko Sato , Shuitsu Fujii , Takuya Urayama , Akinori Shida , Raju Ramasamy , Kazunari Fujioka , Tatsuyuki Nakatani
发明人： Takehiko Sato , Shuitsu Fujii , Takuya Urayama , Akinori Shida , Raju Ramasamy , Kazunari Fujioka , Tatsuyuki Nakatani
IPC分类号： A61L2/02 , A61L2/00
CPC分类号： A61L2/14 , H05H1/30 , H05H2245/1225
摘要： A method of low temperature sterilization that with the use of a compact simple apparatus, is capable of safe, unfailing sterilization. There is provided an apparatus comprising gas cylinder (gas supply source)(8), high energy particle generation part (1-3) capable of generating a gas of temperature nonequilibrium condition containing high energy particles through exciting of the gas supplied from the gas cylinder (8) and gas blow part (4) capable of jetting the gas of temperature nonequilibrium condition generated by the high energy particle generation part (1-3) over pathogenic microbes positioned outside.
摘要翻译：一种低温灭菌方法，通过使用紧凑简单的装置，能够安全，可靠地灭菌。提供了一种装置，包括气瓶（气体供给源）（8），高能粒子产生部分（1-3），能够产生含有高能粒子的温度非平衡状态的气体，该气体通过从气瓶（8）和气体吹出部分（4），其能够喷射由高能粒子产生部分（1-3）产生的温度非平衡状态的气体超过位于外部的致病微生物。

2. 发明申请

US20120187086A1 PLASMA GENERATION SYSTEM AND PLASMA GENERATION METHOD 有权
标题翻译：等离子体发生系统和等离子体生成方法
公开(公告)号：US20120187086A1
公开(公告)日：2012-07-26
申请号：US13437488
申请日：2012-04-02
申请人： Takehiko SATO , Tatsuyuki Nakatani , Tatsuo Kimura
发明人： Takehiko SATO , Tatsuyuki Nakatani , Tatsuo Kimura
IPC分类号： H05H1/24 , B44C1/22 , A61L2/03
CPC分类号： H05H1/2406 , A61L2/14 , H05H2001/2412
摘要： A plasma generation system and related method for generating plasma in a cavity of a narrow tube, the system including: a first electrode including a conductive member covered with an insulator or dielectric, the first electrode being inserted into the cavity of the narrow tube to generate the plasma; a power supply to apply an alternating voltage or pulse voltage to the first electrode; and a second electrode located outside the narrow tube and connected to the power supply, the power supply applying the alternating voltage or pulse voltage between the first electrode and the second electrode, wherein the conductive member is made of a wire, a portion of the narrow tube is provided between the first electrode and the second electrode, and the second electrode is arranged and shaped so that a discharge is unevenly performed in a circumferential direction of the first electrode.
摘要翻译：一种用于在窄管的空腔中产生等离子体的等离子体产生系统和相关方法，所述系统包括：第一电极，包括被绝缘体或电介质覆盖的导电构件，所述第一电极插入所述窄管的空腔中以产生等离子体用于向所述第一电极施加交流电压或脉冲电压的电源; 以及第二电极，位于所述窄管的外部并连接到所述电源，所述电源在所述第一电极和所述第二电极之间施加交流电压或脉冲电压，其中所述导电构件由导线制成，所述狭窄部分管设置在第一电极和第二电极之间，并且第二电极被布置和成形为使得在第一电极的圆周方向上不均匀地进行放电。

3. 发明授权

US08168130B2 Plasma generation system and plasma generation method 有权
标题翻译：等离子体发生系统和等离子体生成方法
公开(公告)号：US08168130B2
公开(公告)日：2012-05-01
申请号：US11992007
申请日：2006-08-11
申请人： Takehiko Sato , Tatsuyuki Nakatani , Tatsuo Kimura
发明人： Takehiko Sato , Tatsuyuki Nakatani , Tatsuo Kimura
IPC分类号： B01J19/08 , A61L9/00 , H05H1/24
CPC分类号： H05H1/2406 , A61L2/14 , H05H2001/2412
摘要： A method and system for surely and conveniently generating plasma in a narrow tube having a small diameter.A first electrode formed by a conductive member covered with an insulator or dielectric is inserted into a narrow tube. The narrow tube is located on a second electrode. A power supply applies an alternating voltage or pulse voltage between the first electrode and the second electrode so that plasma is generated in the narrow tube around the first electrode.
摘要翻译：一种用于在具有小直径的窄管中可靠和方便地产生等离子体的方法和系统。由绝缘体或电介质覆盖的导电构件形成的第一电极被插入到窄管中。窄管位于第二电极上。电源在第一电极和第二电极之间施加交流电压或脉冲电压，使得在第一电极周围的窄管中产生等离子体。

4. 发明授权

US08501106B2 Plasma generation system and plasma generation method 有权
标题翻译：等离子体发生系统和等离子体生成方法
公开(公告)号：US08501106B2
公开(公告)日：2013-08-06
申请号：US13437488
申请日：2012-04-02
申请人： Takehiko Sato , Tatsuyuki Nakatani , Tatsuo Kimura
发明人： Takehiko Sato , Tatsuyuki Nakatani , Tatsuo Kimura
IPC分类号： B01J19/08
CPC分类号： H05H1/2406 , A61L2/14 , H05H2001/2412
摘要： A plasma generation system and related method for generating plasma in a cavity of a narrow tube, the system including: a first electrode including a conductive member covered with an insulator or dielectric, the first electrode being inserted into the cavity of the narrow tube to generate the plasma; a power supply to apply an alternating voltage or pulse voltage to the first electrode; and a second electrode located outside the narrow tube and connected to the power supply, the power supply applying the alternating voltage or pulse voltage between the first electrode and the second electrode, wherein the conductive member is made of a wire, a portion of the narrow tube is provided between the first electrode and the second electrode, and the second electrode is arranged and shaped so that a discharge is unevenly performed in a circumferential direction of the first electrode.
摘要翻译：一种用于在窄管的空腔中产生等离子体的等离子体产生系统和相关方法，所述系统包括：第一电极，包括被绝缘体或电介质覆盖的导电构件，所述第一电极插入所述窄管的空腔中以产生等离子体用于向所述第一电极施加交流电压或脉冲电压的电源; 以及第二电极，位于所述窄管的外部并连接到所述电源，所述电源在所述第一电极和所述第二电极之间施加交流电压或脉冲电压，其中所述导电构件由导线制成，所述狭窄部分管设置在第一电极和第二电极之间，并且第二电极被布置和成形为使得在第一电极的圆周方向上不均匀地进行放电。

5. 发明申请

US20090005862A1 Stent and Method For Fabricating the Same 失效
标题翻译：支架及其制造方法
公开(公告)号：US20090005862A1
公开(公告)日：2009-01-01
申请号：US12088000
申请日：2007-01-15
申请人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Ikuo Komura , Koji Mori
发明人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Ikuo Komura , Koji Mori
IPC分类号： A61F2/06
CPC分类号： A61L31/084 , A61F2/91 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L33/025 , A61L2300/416 , A61L2300/606 , A61L2420/08
摘要： A stent includes a tubular stent body 11, a diamond-like carbon film 12 formed on the surface of the stent body 11 and having an activated surface, and a polymer layer 13 immobilized on the surface of the diamond-like carbon film. The polymer layer 13 contains a drug 14 having an effect to prevent restenosis, and the drug 14 is gradually released from the polymer layer 13.
摘要翻译：支架包括管状支架体11，形成在支架主体11的表面上并具有活化表面的类金刚石碳膜12和固定在金刚石状碳膜表面上的聚合物层13。聚合物层13含有具有防止再狭窄作用的药物14，药物14从聚合物层13逐渐释放。

6. 发明申请

US20110318714A1 IMPLANT MATERIAL AND METHOD FOR MANUFACTURING THE SAME 审中-公开
标题翻译：植入材料及其制造方法
公开(公告)号：US20110318714A1
公开(公告)日：2011-12-29
申请号：US13148928
申请日：2009-02-10
申请人： Hiroki Nikawa , Seichiyou Makihira , Yuichi Mine , Yoshinori Abe , Tatsuyuki Nakatani , Keishi Okamoto , Yuki Nitta
发明人： Hiroki Nikawa , Seichiyou Makihira , Yuichi Mine , Yoshinori Abe , Tatsuyuki Nakatani , Keishi Okamoto , Yuki Nitta
IPC分类号： A61C5/08 , C23C14/34 , A61C5/00 , C04B35/565 , B32B15/04
CPC分类号： A61L27/025 , A61K6/027 , A61L27/303 , A61L27/306 , A61L2420/04 , C23C16/30 , Y10T428/31678
摘要： An implant material includes a base material, and a silicon-containing carbon thin film formed on a surface of the base material. The carbon thin film contains a C—C component in which carbon atoms are bonded, and a SiC component in which carbon and silicon atoms are bonded, and a ratio of the SiC component is 0.06 or higher.
摘要翻译：植入材料包括基材和形成在基材表面上的含硅碳薄膜。碳薄膜含有碳原子键合的C-C成分和碳和硅原子键合的SiC成分，SiC成分的比例为0.06以上。

7. 发明授权

US07931934B2 Medical device having diamond-like thin film and method for manufacturing thereof 有权
标题翻译：具有类金刚石薄膜的医疗装置及其制造方法
公开(公告)号：US07931934B2
公开(公告)日：2011-04-26
申请号：US12301003
申请日：2007-01-15
申请人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Koji Mori , Ikuo Komura
发明人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Koji Mori , Ikuo Komura
IPC分类号： B05D3/00 , H01L29/15 , A61F2/06
CPC分类号： A61L31/088 , A61F2/0077 , A61L31/10 , A61M25/0045 , C08L43/04
摘要： A medical device includes a medial device body, and a diamond-like thin film covering the medical device body and containing silicon. The diamond-like thin film has a concentration of silicon which is lower in a surface thereof than in an interface thereof with the medical device body mentioned above, and continuously varies.
摘要翻译：医疗装置包括中间装置主体和覆盖医疗装置主体并且含有硅的金刚石状薄膜。菱形薄膜的表面的硅浓度比上述医疗装置体的界面低，连续变化。

8. 发明申请

US20110060403A9 Stent and Method For Fabricating the Same 失效
标题翻译：支架及其制造方法
公开(公告)号：US20110060403A9
公开(公告)日：2011-03-10
申请号：US12088000
申请日：2007-01-15
申请人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Ikuo Komura , Koji Mori
发明人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Ikuo Komura , Koji Mori
IPC分类号： A61F2/06
CPC分类号： A61L31/084 , A61F2/91 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L33/025 , A61L2300/416 , A61L2300/606 , A61L2420/08
摘要： A stent includes a tubular stent body 11, a diamond-like carbon film 12 formed on the surface of the stent body 11 and having an activated surface, and a polymer layer 13 immobilized on the surface of the diamond-like carbon film. The polymer layer 13 contains a drug 14 having an effect to prevent restenosis, and the drug 14 is gradually released from the polymer layer 13.
摘要翻译：支架包括管状支架体11，形成在支架主体11的表面上并具有活化表面的类金刚石碳膜12和固定在金刚石状碳膜表面上的聚合物层13。聚合物层13含有具有防止再狭窄作用的药物14，药物14从聚合物层13逐渐释放。

9. 发明申请

US20070207321A1 Method For Treating Surface Of Material, Surface-Treated Material, Medical Material, And Medical Instrument 审中-公开
标题翻译：处理材料，表面处理材料，医疗材料和医疗仪器的方法
公开(公告)号：US20070207321A1
公开(公告)日：2007-09-06
申请号：US10594918
申请日：2005-03-25
申请人： Yoshinori Abe , Tatsuyuki Nakatani , Keishi Okamoto , Kohei Shiraishi , Kazuo Sugiyama
发明人： Yoshinori Abe , Tatsuyuki Nakatani , Keishi Okamoto , Kohei Shiraishi , Kazuo Sugiyama
IPC分类号： B32B27/38 , C23C16/00
CPC分类号： C23C16/56 , A61F2310/0058 , A61L27/303 , A61L29/103 , A61L31/084 , C01B32/28 , C23C16/26 , Y10T428/31504 , Y10T428/31511 , Y10T428/3154
摘要： A diamond-like carbon film (DLC film) is formed on the surface of a base material made of an inorganic material, such as ceramics, or the like, or an organic material, such as resin, or the like. The surface of the resultant DLC film is treated with plasma, or the like, so as to be activated. Various monomers having biocompatibility, etc., are graft-polymerized to the activated surface of the DLC film, whereby a polymer layer is formed from the monomers grafted to the surface of the DLC film. Thus, the base material coated with the DLC film modified with a polymer which does not readily separate can be realized.
摘要翻译：在由诸如陶瓷等的无机材料制成的基材的表面上，或诸如树脂等有机材料的表面上形成类金刚石碳膜（DLC膜）。用等离子体等处理得到的DLC膜的表面，使其活化。具有生物相容性等的各种单体被接枝聚合到DLC膜的活化表面上，由此由接枝到DLC膜表面的单体形成聚合物层。因此，可以实现用不易分离的聚合物改性的DLC膜涂覆的基材。

10. 发明授权

US09163149B2 Implant material 有权
标题翻译：植入材料
公开(公告)号：US09163149B2
公开(公告)日：2015-10-20
申请号：US13807267
申请日：2011-06-30
申请人： Akira Mochizuki , Yuki Nitta , Keishi Okamoto , Tatsuyuki Nakatani
发明人： Akira Mochizuki , Yuki Nitta , Keishi Okamoto , Tatsuyuki Nakatani
IPC分类号： A61F2/28 , A61F2/30 , A61L27/30 , C09D5/00 , A61C8/00 , A61K6/00 , A61C5/08 , A61C13/01 , A61C13/08
CPC分类号： C09D5/00 , A61C5/70 , A61C5/73 , A61C5/77 , A61C8/0012 , A61C8/0013 , A61C13/01 , A61C13/08 , A61F2/30767 , A61F2002/3093 , A61K6/0044 , A61L27/303 , A61L2430/02 , A61L2430/12 , Y10T428/31678
摘要： An implant material includes: a base material 10; and a carbonaceous film 20 provided on a surface of the base material 10. The carbonaceous film 20 includes carbon atoms, oxygen atoms, and nitrogen atoms in a surface thereof, and the carbon atoms are bonded to the oxygen atoms to form carboxyl carbon and carbon having a single bond with oxygen. In the surface of the carbonaceous film 20, a content of nitrogen atoms is greater than or equal to 8.0 at. %, a content of carbon having a single bond with oxygen is greater than or equal to 5.4%, and a content of carboxyl carbon is less than or equal to 3.1%.
摘要翻译：植入材料包括：基材10; 以及设置在基材10的表面上的碳质膜20.碳质膜20的表面含有碳原子，氧原子和氮原子，碳原子与氧原子键合而形成羧基碳和碳与氧单键。在碳质膜20的表面，氮原子的含量大于或等于8.0at。％，与氧具有单键的碳含量大于或等于5.4％，羧基碳含量小于或等于3.1％。

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