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1. 发明授权

US07192456B2 Method of preparing a purified purple corn coloring agent 有权
标题翻译：制备纯化的紫色玉米着色剂的方法
公开(公告)号：US07192456B2
公开(公告)日：2007-03-20
申请号：US10502058
申请日：2002-02-01
申请人： Takahito Ichi , Makoto Sakata , Hiromitsu Aoki , Takatoshi Koda
发明人： Takahito Ichi , Makoto Sakata , Hiromitsu Aoki , Takatoshi Koda
IPC分类号： C09B61/00
CPC分类号： C09B67/0096 , A23L5/43 , C09B61/00
摘要： A method of preparing a purified purple corn coloring agent comprising passing a purple corn color extract solution through an adsorption resin, washing with water, and releasing the purple corn color from the resin with the use of an aqueous solution containing alcohol of 25 to 45 v/vt %.
摘要翻译：一种制备纯化的紫色玉米着色剂的方法，包括使紫色玉米色提取物溶液通过吸附树脂，用水洗涤，并使用含有25至45v的醇的水溶液从树脂中释放紫色玉米色 / vt％。

2. 发明申请

US20050125915A1 Purified purple corn color and method of preparing the same 有权
标题翻译：纯紫玉米色及其制备方法
公开(公告)号：US20050125915A1
公开(公告)日：2005-06-16
申请号：US10502058
申请日：2002-02-01
申请人： Takahito Ichi , Makoto Sakata , Hiromitsu Aoki , Takatoshi Koda
发明人： Takahito Ichi , Makoto Sakata , Hiromitsu Aoki , Takatoshi Koda
IPC分类号： A23L1/275 , C09B61/00 , C09B67/54
CPC分类号： C09B67/0096 , A23L5/43 , C09B61/00
摘要： Purple corn color which has a high safety and no odor in odor components since impurities (odor components, precursor thereof, a mycotoxin fumonisintc) seemingly contained in the purple corn material have been eliminated therefrom; and color preparations containing the same. This purple corn color can be obtained by a preparation method comprising passing a purple corn color extract solution through an adsorption resin, washing with water, and releasing the purple corn color from the resin with the use of an aqueous solution containing alcohol of 25 to 45 v/vt %.
摘要翻译：紫色玉米材料中似乎含有的杂质（气味成分，其前体，真菌毒素，伏马毒素）已被除去，具有安全性高，气味成分无异味的紫色玉米色素，和含有相同颜色的制剂。这种紫色玉米颜色可以通过包括使紫色玉米色提取物溶液通过吸附树脂，用水洗涤并使用含有25至45的醇的水溶液从树脂中释放紫色玉米颜色的制备方法获得 v / vt％。

3. 发明授权

US07261904B2 Purified cochineal and method for its production 有权
标题翻译：纯化的胭脂虫及其生产方法
公开(公告)号：US07261904B2
公开(公告)日：2007-08-28
申请号：US10428995
申请日：2003-05-05
申请人： Takahito Ichi , Takatoshi Koda , Chiyoki Yukawa , Makoto Sakata , Hiroyuki Sato
发明人： Takahito Ichi , Takatoshi Koda , Chiyoki Yukawa , Makoto Sakata , Hiroyuki Sato
IPC分类号： A61K35/64 , C12P1/00
CPC分类号： C09B61/00
摘要： The invention provides a cochineal color, a colorant product containing the cochineal color and the method of its production, wherein the cochineal color is free of allergenic proteins and contaminants derived from the raw material Coccus cacti L. insect and can be added with safety to products taken by mouth, such as foods, pharmaceutical products, etc. The invention relates to a cochineal color substantially free of proteins of molecular weight not less than 6000. The invention also relates to a process for producing a cochineal color which comprises subjecting a cochineal extract solution to proteolysis and then to at least one treatment selected from the group consisting of adsorption treatment, ion exchange treatment, acid treatment, extraction treatment and membrane treatment.
摘要翻译：本发明提供了一种胭脂红色，含有胭脂红色的着色剂及其制造方法，其中胭脂红颜色不含有来自原料椰子树昆虫的过敏原蛋白质和污染物，并且可以安全地添加到产品中本发明涉及基本上不含分子量不小于6000的蛋白质的胭脂虫色素。本发明还涉及一种生产胭脂红色的方法，其包括使胭脂虫提取物然后进行至少一种选自吸附处理，离子交换处理，酸处理，提取处理和膜处理的处理。

4. 发明申请

US20090082285A1 Adiponectin expression promoter 审中-公开
标题翻译：脂联素表达启动子
公开(公告)号：US20090082285A1
公开(公告)日：2009-03-26
申请号：US12153102
申请日：2008-05-14
申请人： Takanori Tsuda , Toshihiko Osawa , Yuki Ueno , Hiromitsu Aoki , Kouji Utida , Takatoshi Koda
发明人： Takanori Tsuda , Toshihiko Osawa , Yuki Ueno , Hiromitsu Aoki , Kouji Utida , Takatoshi Koda
IPC分类号： A61K31/7048 , A61K31/352
CPC分类号： C07D311/62 , A23L33/10 , A61K31/352 , A61K31/7048
摘要： To prevent or alleviate various pathologies caused by lifestyle-related diseases, etc., the present invention provides a substance having an effect of promoting the expression and elevating the expression level of adiponectin, and applications thereof. An adiponectin expression promoting agent containing, as an active ingredient, at least one cyanidin compound selected from the group consisting of cyanidin and cyanidin glycosides can be applied to pharmaceutical or food compositions for use in applications in which the pharmacological effects of adiponectin are utilized.
摘要翻译：为了防止或减轻与生活方式相关的疾病等引起的各种病症，本发明提供具有促进脂联素表达和提高脂联素表达水平的作用的物质及其应用。含有作为活性成分的至少一种选自花青素和花青素苷的花青素化合物的脂联素表达促进剂可以应用于药物或食品组合物，用于其中利用脂连蛋白的药理作用的应用中。

5. 发明申请

US20060234957A1 Adiponectin expression promoter 审中-公开
公开(公告)号：US20060234957A1
公开(公告)日：2006-10-19
申请号：US10546808
申请日：2004-03-02
申请人： Takanori Tsuda , Toshihiko Osawa , Yuki Ueno , Hiromitsu Aoki , Kouji Utida , Takatoshi Koda
发明人： Takanori Tsuda , Toshihiko Osawa , Yuki Ueno , Hiromitsu Aoki , Kouji Utida , Takatoshi Koda
IPC分类号： A61K31/7048 , A61K31/343 , A61K36/899 , A61K36/45 , A61K36/31 , A61K36/48 , A61K36/73 , A61K36/87
CPC分类号： C07D311/62 , A23L33/10 , A61K31/352 , A61K31/7048
摘要： To prevent or alleviate various pathologies caused by lifestyle-related diseases, etc., the present invention provides a substance having an effect of promoting the expression and elevating the expression level of adiponectin, and applications thereof. An adiponectin expression promoting agent containing, as an active ingredient, at least one cyanidin compound selected from the group consisting of cyanidin and cyanidin glycosides can be applied to pharmaceutical or food compositions for use in applications in which the pharmacological effects of adiponectin are utilized.

6. 发明申请

US20050084548A1 Antiobestic and/or antidiabetic agent containing cyanidin 3-glucoside as active ingredient 审中-公开
标题翻译：含有花青素3-葡萄糖苷作为有效成分的抗生素和/或抗糖尿病药
公开(公告)号：US20050084548A1
公开(公告)日：2005-04-21
申请号：US10504910
申请日：2002-07-04
申请人： Takanori Tsuda , Fumihiko Horio , Toshihiko Osawa , Koji Uchida , Hiromitsu Aoki , Takatoshi Koda
发明人： Takanori Tsuda , Fumihiko Horio , Toshihiko Osawa , Koji Uchida , Hiromitsu Aoki , Takatoshi Koda
IPC分类号： A23L1/30 , A23L2/02 , A61K31/7048 , A61K36/899 , A61P3/04 , A61P3/10 , C07H17/065 , A61K35/78 , A61K47/00
CPC分类号： A61K31/7048 , A23L2/02 , A23L33/105 , A23V2002/00 , A23V2200/15 , A23V2250/264 , A23V2250/032
摘要： The invention provides an antiobestic and/or antidiabetic agent containing cyanidin 3-glucoside as an active ingredient. Thereby the increase of adipose cells can be suppressed and the blood glucose level can be reduced safely and effectively.
摘要翻译：本发明提供含有花青素3-葡萄糖苷作为活性成分的抗胆碱和/或抗糖尿病药。从而能够抑制脂肪细胞的增加，能够安全有效地降低血糖值。

7. 发明申请

US20060288438A1 Novel miniature inverted-repeat transposable elements (MITEs)-like element and transcriptional activation element 审中-公开
标题翻译：新型微型倒置重复转座元件（MITEs）样元素和转录激活元件
公开(公告)号：US20060288438A1
公开(公告)日：2006-12-21
申请号：US11446828
申请日：2006-06-05
申请人： Yoshihiro Ozeki , Takashi Fukuda , Mikiko Oyanagi , Takatoshi Koda
发明人： Yoshihiro Ozeki , Takashi Fukuda , Mikiko Oyanagi , Takatoshi Koda
IPC分类号： A01H1/00 , C12N15/82
CPC分类号： C12N15/8201 , C07K14/415
摘要： The invention provides novel, carrot-derived MITE-like elements (transposable elements). It further provides transcriptional activation elements comprising at least one transposable element, in particular one of the above MITE-like elements. Specifically, it provides transcriptional activation elements having a DNA comprising the nucleotide sequence shown under SEQ ID NO:1 or a functional equivalent thereto and/or a DNA comprising the nucleotide sequence shown under SEQ ID NO:2 or a functional equivalent thereto. The transcriptional activation elements of the invention can increase or activate the reduced expression of a foreign gene introduced by the transgenic technology. Therefore, the transcriptional activation elements contribute to stable expression of a foreign gene introduced in a plant genome and are useful in stably producing genetically modified plants.
摘要翻译：本发明提供了新颖的，由胡萝卜衍生的MITE样元件（转座元件）。其进一步提供转录激活元件，其包含至少一个转座元件，特别是上述MITE样元件之一。具体地说，它提供具有包含SEQ ID NO：1所示核苷酸序列或其功能等同物的DNA的转录激活元件和/或包含SEQ ID NO：2所示核苷酸序列或其功能等同物的DNA。本发明的转录激活元件可以增加或激活由转基因技术引入的外源基因的降低的表达。因此，转录激活元件有助于在植物基因组中引入的外源基因的稳定表达，并且可用于稳定生产转基因植物。

8. 发明申请

US20060051472A1 Method for suppressing fading of tar colorant, and fading-suppressed tar colorant-containing composition 审中-公开
标题翻译：用于抑制焦油着色剂褪色的方法和含有褪色抑制焦油着色剂的组合物
公开(公告)号：US20060051472A1
公开(公告)日：2006-03-09
申请号：US11123048
申请日：2005-05-06
申请人： Takatoshi Koda , Masamitsu Moriwaki , Hisashi Tanaka , Kouji Utida
发明人： Takatoshi Koda , Masamitsu Moriwaki , Hisashi Tanaka , Kouji Utida
IPC分类号： A23B7/157
CPC分类号： A23L3/26 , A23L3/3463 , A23L3/3472
摘要： The present invention provides a method of suppressing fading of a tar colorant. More specifically, the present invention provides a method of suppressing a tar colorant fading phenomenon that occurs specifically in compositions containing (a) the tar colorant, and (b) at least one of reducing sugars, ascorbic acid compounds, or metals. This method can be attained by mixing (c) at least one selected from the group consisting of isoquercitrin, enzymatically modified isoquercitrin, rutin, enzymatically modified rutin, Chinese bayberry extract, and rosemary extract into such a composition, thus making the component (a), the component (b) and the component (c) coexist. The present invention further provides a composition for which fading of a tar colorant is suppressed using the above method, more specifically a composition containing at least one of reducing sugars, ascorbic acid compounds, or metals in addition to the tar colorant.
摘要翻译：本发明提供抑制焦油着色剂褪色的方法。更具体地说，本发明提供一种抑制在含有（a）焦油着色剂的组合物中具体发生的焦油着色剂褪色现象的方法，和（b）还原糖，抗坏血酸化合物或金属中的至少一种。该方法可以通过将（c）选自异槲皮素，酶促改性的异槲皮苷，芦丁，酶促改性芦丁，中国杨梅提取物和迷迭香提取物中的至少一种混合到这样的组合物中，从而使组分（a），组分（b）和组分（c）共存。本发明还提供一种组合物，其中使用上述方法抑制焦油着色剂的褪色，更具体地说，除了焦油着色剂之外还包含含有还原糖，抗坏血酸化合物或金属中的至少一种的组合物。

9. 发明授权

US06572906B1 Method for inhibiting fading of a natural pigment using nigerooligosaccharide or maltooligosaccharide or panose with or without an antioxidant 失效
标题翻译：使用具有或不具有抗氧化剂的黑寡糖或麦芽低聚糖或甘露抑制天然色素褪色的方法
公开(公告)号：US06572906B1
公开(公告)日：2003-06-03
申请号：US09594736
申请日：2000-06-16
申请人： Yutaka Higashimura , Kazuhiro Emura , Noriko Kuze , Junko Shirai , Takatoshi Koda
发明人： Yutaka Higashimura , Kazuhiro Emura , Noriko Kuze , Junko Shirai , Takatoshi Koda
IPC分类号： A23L127
CPC分类号： A61K9/0095 , A23L2/58 , A23L5/00 , A23L5/41 , A23L5/43 , A23L5/44 , A23L9/00 , A23L21/00 , A23L27/60 , A23L29/231 , A23L29/30 , A23L33/105 , A23V2002/00 , A61K47/26 , C09B61/00 , A23V2250/606 , A23V2250/032 , A23V2200/048 , A23V2200/044
摘要： The present invention provide an anti-fading agent for a pigment, characterized by comprising as active ingredients at least one oligosaccharide selected from the group consisting of nigerooligosaccharide, maltooligosaccharide and panose, when so required, in addition of an antioxidant. The anti-fading agent of the invention can advantageously inhibit fading in colors (including fading in colors by light irradiation and heat treatment) of natural pigments such as anthocyanin-based pigments, flavonoid-based pigments, carotenoid-based pigments and the like, and is useful for colored beverage and food products, pharmaceutical drugs, cosmetics and the like with which the fading in colors may be a problem.
摘要翻译：本发明提供了一种用于颜料的抗褪色剂，其特征在于，除了抗氧化剂之外，还包含作为活性成分的至少一种选自由低聚半乳糖，麦芽低聚糖和苹果糖组成的组的寡糖。本发明的抗褪色剂可以有利地抑制天然颜料如花青素类颜料，类黄酮类颜料，类胡萝卜素类颜料等的颜色褪色（包括光照射和热处理的褪色），以及对于颜色褪色可能是问题的彩色饮料和食品，药物，化妆品等有用。

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