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1. 发明申请

US20110102799A1 Multi-Grating Biosensor For Label-Independent Optical Readers 有权
标题翻译：用于标签无关光学读取器的多光栅生物传感器
公开(公告)号：US20110102799A1
公开(公告)日：2011-05-05
申请号：US12915856
申请日：2010-10-29
申请人： Steven R. Matejka , Robert Adam Modavis , David Andrew Pastel , Garrett Andrew Piech
发明人： Steven R. Matejka , Robert Adam Modavis , David Andrew Pastel , Garrett Andrew Piech
IPC分类号： G01N21/55 , G02B6/10
CPC分类号： G01N21/7743 , G01N21/253 , G01N21/276
摘要： A multi-grating resonant waveguide (RWG) biosensor for an optical reader system having a spatial resolution limit is disclosed. The multi-grating RWG biosensor includes one or more signal-grating regions and one or more reference-grating regions. The multi-grating RWG biosensor can also include a non-resonance region that spatially separates the one or more signal-grating regions, that spatially separates the one or more reference-grating regions, and that spatially separates the one or more reference-grating regions from the one or more signal-grating regions. The non-resonance region can have a minimum width greater than the optical reader system spatial resolution limit. The RWG biosensor can have an asymmetric split-grating configuration. Methods of measuring a signal resonant wavelength of a multi-grating RWG biosensor using an optical reader having a spatial resolution limit are also disclosed.
摘要翻译：公开了一种具有空间分辨率极限的光学读取器系统的多光栅谐振波导（RWG）生物传感器。多光栅RWG生物传感器包括一个或多个信号光栅区域和一个或多个参考光栅区域。多光栅RWG生物传感器还可以包括空间上分离一个或多个信号光栅区域的非共振区域，其在空间上分离一个或多个参考光栅区域，并且在空间上分离一个或多个参考光栅区域从一个或多个信号光栅区域。非共振区域可以具有大于光学读取器系统空间分辨率极限的最小宽度。 RWG生物传感器可以具有非对称分裂光栅配置。还公开了使用具有空间分辨率极限的光学读取器来测量多光栅RWG生物传感器的信号谐振波长的方法。

2. 发明授权

US08619260B2 Multi-grating biosensor for label-independent optical readers 有权
标题翻译：用于标签无关光学读取器的多光栅生物传感器
公开(公告)号：US08619260B2
公开(公告)日：2013-12-31
申请号：US12915856
申请日：2010-10-29
申请人： Steven R Matejka , Robert Adam Modavis , David Andrew Pastel , Garrett Andrew Piech , Christopher L. Timmons
发明人： Steven R Matejka , Robert Adam Modavis , David Andrew Pastel , Garrett Andrew Piech , Christopher L. Timmons
IPC分类号： G01N21/55 , G01J3/30 , G01J3/28
CPC分类号： G01N21/7743 , G01N21/253 , G01N21/276
摘要： A multi-grating resonant waveguide (RWG) biosensor for an optical reader system having a spatial resolution limit is disclosed. The multi-grating RWG biosensor includes one or more signal-grating regions and one or more reference-grating regions. The multi-grating RWG biosensor can also include a non-resonance region that spatially separates the one or more signal-grating regions, that spatially separates the one or more reference-grating regions, and that spatially separates the one or more reference-grating regions from the one or more signal-grating regions. The non-resonance region can have a minimum width greater than the optical reader system spatial resolution limit. The RWG biosensor can have an asymmetric split-grating configuration. Methods of measuring a signal resonant wavelength of a multi-grating RWG biosensor using an optical reader having a spatial resolution limit are also disclosed.
摘要翻译：公开了一种具有空间分辨率极限的光学读取器系统的多光栅谐振波导（RWG）生物传感器。多光栅RWG生物传感器包括一个或多个信号光栅区域和一个或多个参考光栅区域。多光栅RWG生物传感器还可以包括在空间上分离一个或多个信号光栅区域的非共振区域，其在空间上分离一个或多个参考光栅区域，并且在空间上分离一个或多个参考光栅区域从一个或多个信号光栅区域。非共振区域可以具有大于光学读取器系统空间分辨率极限的最小宽度。 RWG生物传感器可以具有非对称分裂光栅配置。还公开了使用具有空间分辨率极限的光学读取器来测量多光栅RWG生物传感器的信号谐振波长的方法。

3. 发明授权

US08325332B2 Start-up methods for frequency converted light sources 失效
标题翻译：变频光源的启动方法
公开(公告)号：US08325332B2
公开(公告)日：2012-12-04
申请号：US12908117
申请日：2010-10-20
申请人： Garrett Andrew Piech , Dragan Pikula , Daniel Ohen Ricketts
发明人： Garrett Andrew Piech , Dragan Pikula , Daniel Ohen Ricketts
IPC分类号： G01B11/26
CPC分类号： H01S5/0092 , G02B6/4225 , G02F1/353 , H01S5/0014 , H01S5/06256 , H01S5/0687 , H01S5/4093
摘要： Start-up methods for frequency converted light sources and projector systems comprising frequency converted light sources are described herein. The start-up methods generally comprise modulating the frequency converted light source over three degrees of freedom (two spatial dimensions and one wavelength dimension). Specifically, fast oscillation of an axis of an adjustable optical component is performed simultaneously with fast oscillation of a wavelength of the semiconductor laser while a second axis of the adjustable optical component is incrementally stepped and the output intensity of the frequency converted light source is monitored for each step. This start-up method allows for three linear searches to be used to rapidly locate the appropriate control settings for the frequency converted light source.
摘要翻译：本文描述了包括频率转换光源的变频光源和投影仪系统的启动方法。启动方法通常包括在三个自由度（两个空间维度和一个波长尺寸）上调制频率转换的光源。具体地，可调节光学部件的轴的快速振荡与半导体激光器的波长的快速振荡同时进行，同时可调光学部件的第二轴增量阶梯，并且监视频率转换光源的输出强度每一步。该启动方法允许使用三个线性搜索来快速定位频率转换光源的适当控制设置。

4. 发明申请

US20120221264A1 APPARATUS AND METHOD FOR DETERMINING SPARKLE 有权
标题翻译：用于确定SP。的装置和方法
公开(公告)号：US20120221264A1
公开(公告)日：2012-08-30
申请号：US13354827
申请日：2012-01-20
申请人： Jacques Gollier , Shandon Dee Hart , Garrett Andrew Piech , James Andrew West
发明人： Jacques Gollier , Shandon Dee Hart , Garrett Andrew Piech , James Andrew West
IPC分类号： G06F19/00 , G01R31/44
CPC分类号： G02F1/1309 , G01J1/18 , G01J1/4228 , G01J2001/4247 , G02F1/133502
摘要： An apparatus and method for determining and quantifying “sparkle”—the random noise that is generated when a pixelated image is viewed through a roughened surface of a transparent sample. The apparatus includes a pixelated source and an imaging system located in an optical path originating from the pixelated source, wherein a transparent sample may be placed in the optical path between the pixelated source and the optical system. The degree of sparkle is determined by obtaining an integrated image for the pixelated image; and calculating a standard deviation of the integrated pixel power. An objective level of sparkle can be defined by correlating the amount of sparkle provided by the apparatus with visual impressions.
摘要翻译：用于确定和量化“闪烁”的装置和方法 - 当通过透明样品的粗糙表面观察像素化图像时产生的随机噪声。该装置包括位于源自像素化源的光路中的像素化源和成像系统，其中可以将透明样品放置在像素化源和光学系统之间的光路中。通过获得用于像素化图像的积分图像来确定闪光度; 并计算积分像素功率的标准偏差。可以通过将设备提供的闪光量与视觉印象相关联来定义闪光的客观水平。

5. 发明申请

US20110188038A1 Label-Independent Optical Reader System And Methods With Optical Scanning 审中-公开
标题翻译：标签独立光学读取器系统和光学扫描方法
公开(公告)号：US20110188038A1
公开(公告)日：2011-08-04
申请号：US12850075
申请日：2010-08-04
申请人： Jacques Gollier , Garrett Andrew Piech , Michael Brian Webb
发明人： Jacques Gollier , Garrett Andrew Piech , Michael Brian Webb
IPC分类号： G01J3/28
CPC分类号： G01N21/7743 , G02B26/0833 , G02B26/101
摘要： Optical reader systems and methods for label-independent reading of resonant waveguide (RWG) biosensors operably supported by a microplate as defined herein. The system includes a light source, a spectrometer unit, a beam-forming optical system and a scanning optical system that includes a scanning mirror device, a mirror device driver operably coupled to the scanning mirror device, and an F-theta lens arranged between the microplate and the beam-forming optical system. Some systems use multiple optical beams to scan multiple biosensors at once without having to move the microplate. Asynchronous scanning of multiple beams allows for reducing the number of spectrometer units needed.
摘要翻译：光学读取器系统和用于标签无关读取谐振波导（RWG）生物传感器的方法，其可操作地由如本文定义的微孔板支撑。该系统包括光源，光谱仪单元，波束形成光学系统和扫描光学系统，其包括扫描反射镜装置，可操作地耦合到扫描反射镜装置的反射镜装置驱动器和布置在扫描反射镜装置之间的F-theta透镜微板和波束形成光学系统。一些系统使用多个光束一次扫描多个生物传感器，而不必移动微孔板。多个波束的异步扫描允许减少所需的光谱仪单元的数量。

6. 发明授权

US09411180B2 Apparatus and method for determining sparkle 有权
标题翻译：用于确定闪光的装置和方法
公开(公告)号：US09411180B2
公开(公告)日：2016-08-09
申请号：US13354827
申请日：2012-01-20
申请人： Jacques Gollier , Shandon Dee Hart , Garrett Andrew Piech , James Andrew West
发明人： Jacques Gollier , Shandon Dee Hart , Garrett Andrew Piech , James Andrew West
IPC分类号： G01R31/26 , G02F1/13 , G01J1/18 , G02F1/1335 , G01J1/42
CPC分类号： G02F1/1309 , G01J1/18 , G01J1/4228 , G01J2001/4247 , G02F1/133502
摘要： An apparatus and method for determining and quantifying “sparkle”—the random noise that is generated when a pixelated image is viewed through a roughened surface of a transparent sample. The apparatus includes a pixelated source and an imaging system located in an optical path originating from the pixelated source, wherein a transparent sample may be placed in the optical path between the pixelated source and the optical system. The degree of sparkle is determined by obtaining an integrated image for the pixelated image; and calculating a standard deviation of the integrated pixel power. An objective level of sparkle can be defined by correlating the amount of sparkle provided by the apparatus with visual impressions.
摘要翻译：用于确定和量化“闪烁”的装置和方法 - 当通过透明样品的粗糙表面观察像素化图像时产生的随机噪声。该装置包括位于源自像素化源的光路中的像素化源和成像系统，其中可以将透明样品放置在像素化源和光学系统之间的光路中。通过获得用于像素化图像的积分图像来确定闪光度; 并计算积分像素功率的标准偏差。可以通过将设备提供的闪光量与视觉印象相关联来定义闪光的客观水平。

7. 发明授权

US07414778B1 Wavelength conversion devices and fabrication methods for same 失效
标题翻译：波长转换器件及其制造方法相同
公开(公告)号：US07414778B1
公开(公告)日：2008-08-19
申请号：US11978864
申请日：2007-10-30
申请人： Jacques Gollier , Garrett Andrew Piech
发明人： Jacques Gollier , Garrett Andrew Piech
IPC分类号： G02F1/35 , H01S3/10
CPC分类号： G02F1/3558 , G02F1/3775 , G02F2201/307 , H01S5/0064
摘要： Particular embodiments of the present invention relate generally to a method of fabricating a wavelength conversion device. According to the method, the wavelength conversion device is fabricated by providing a nonlinear optical material and poling the nonlinear optical material to form a plurality of periodically inverted poling domains arranged at an anti-back reflective periodicity Λ. The geometry and the anti-back reflective periodicity Λ of the poled nonlinear material are selected such that the difference between a phase matching wavelength λΦ of the poled nonlinear optical material and a Bragg wavelength λBRAGG of the poled nonlinear optical material is greater than 1 nm.
摘要翻译：本发明的具体实施方案一般涉及制造波长转换装置的方法。根据该方法，通过提供非线性光学材料并极化非线性光学材料以形成以反向反射周期Lambda布置的多个周期性反转的极化畴来制造波长转换器件。极化非线性材料的几何形状和抗背反射周期性λ被选择为使得极化的非线性光学材料的相位匹配波长λPhi 与布拉格波长λBRAGG之间的差极化非线性光学材料的大于1nm。

8. 发明授权

US08294130B2 Methods and systems for optimizing the alignment of optical packages 有权
标题翻译：用于优化光学封装对准的方法和系统
公开(公告)号：US08294130B2
公开(公告)日：2012-10-23
申请号：US12813610
申请日：2010-06-11
申请人： Jacques Gollier , Garrett Andrew Piech , Daniel Ohen Ricketts
发明人： Jacques Gollier , Garrett Andrew Piech , Daniel Ohen Ricketts
IPC分类号： G01N21/86
CPC分类号： G02B26/101 , G02F1/377
摘要： A method for optimizing the alignment of an optical package includes directing a beam spot of a laser along a folded optical path and onto a waveguide portion of a wavelength conversion. The output intensity of the wavelength conversion device is measured as a position of an adjustable optical component is adjusted about a first scanning axis and a second scanning axis thereby traversing the beam spot along a first and second scan lines on the waveguide portion of the wavelength conversion device. The change in the output intensity of the wavelength conversion device is then determined based on the adjusted position of the adjustable optical component. The adjustable optical component is then positioned on the first scanning axis and the second scanning axis based on the determined changes in the output intensity of the wavelength conversion device such that the output intensity of the wavelength conversion device is maximized.
摘要翻译：用于优化光学封装的对准的方法包括将激光束的束斑沿着折叠的光路引导到波长转换的波导部分上。测量波长转换装置的输出强度，因为可调节光学部件的位置围绕第一扫描轴和第二扫描轴进行调节，从而沿着波长转换的波导部分上的第一和第二扫描线遍及光束点设备。然后，基于可调节光学部件的调整位置来确定波长转换装置的输出强度的变化。基于所确定的波长转换装置的输出强度的变化，使可调光学部件位于第一扫描轴和第二扫描轴上，使得波长转换装置的输出强度最大化。

9. 发明申请

US20110303820A1 Methods And Systems For Optimizing The Alignment Of Optical Packages 有权
标题翻译：用于优化光学封装的对准的方法和系统
公开(公告)号：US20110303820A1
公开(公告)日：2011-12-15
申请号：US12813610
申请日：2010-06-11
申请人： Jacques Gollier , Garrett Andrew Piech , Daniel Ohen Ricketts
发明人： Jacques Gollier , Garrett Andrew Piech , Daniel Ohen Ricketts
IPC分类号： G01J1/24 , G01B11/27
CPC分类号： G02B26/101 , G02F1/377
摘要： A method for optimizing the alignment of an optical package includes directing a beam spot of a laser along a folded optical path and onto a waveguide portion of a wavelength conversion. The output intensity of the wavelength conversion device is measured as a position of an adjustable optical component is adjusted about a first scanning axis and a second scanning axis thereby traversing the beam spot along a first and second scan lines on the waveguide portion of the wavelength conversion device. The change in the output intensity of the wavelength conversion device is then determined based on the adjusted position of the adjustable optical component. The adjustable optical component is then positioned on the first scanning axis and the second scanning axis based on the determined changes in the output intensity of the wavelength conversion device such that the output intensity of the wavelength conversion device is maximized.
摘要翻译：用于优化光学封装的对准的方法包括将激光束的束斑沿着折叠的光路引导到波长转换的波导部分上。测量波长转换装置的输出强度，因为可调节光学部件的位置围绕第一扫描轴和第二扫描轴进行调节，从而沿着波长转换的波导部分上的第一和第二扫描线遍及光束点设备。然后，基于可调节光学部件的调整位置来确定波长转换装置的输出强度的变化。基于所确定的波长转换装置的输出强度的变化，使可调光学部件位于第一扫描轴和第二扫描轴上，使得波长转换装置的输出强度最大化。

10. 发明授权

US07835065B2 Optical packages and methods for aligning optical packages 有权
标题翻译：用于对准光学封装的光学封装和方法
公开(公告)号：US07835065B2
公开(公告)日：2010-11-16
申请号：US12200661
申请日：2008-08-28
申请人： Etienne Almoric , Jacques Gollier , Lawrence Hughes , Garrett Andrew Piech
发明人： Etienne Almoric , Jacques Gollier , Lawrence Hughes , Garrett Andrew Piech
IPC分类号： G02F1/35 , G02F2/02 , H01S3/08
CPC分类号： G02B6/4214 , G01B11/272 , G02F1/377 , G02F2001/3546 , H01S5/005 , H01S5/0071 , H01S5/0092
摘要： An optical package includes a semiconductor laser, a wavelength conversion device and a MEMS-actuated mirror oriented on a base module to form a folded optical pathway between an output of the semiconductor laser and an input of the wavelength conversion device. An optical assembly is located in a mechanical positioning device and the mechanical positioning device is disposed on the base module along the optical pathway such that the beam of the semiconductor laser passes through the optical assembly, is reflected by the MEMS-actuated mirror back through the optical assembly and into the waveguide portion of the wavelength conversion device. The MEMS-actuated mirror is operable to scan the beam of the semiconductor laser over the input of the wavelength conversion device. The optical assembly may be adjusted along the optical pathway with the mechanical positioning device to focus the beam into the waveguide portion of the wavelength conversion device.
摘要翻译：光学封装包括半导体激光器，波长转换器件和面向基底模块的MEMS致动镜，以在半导体激光器的输出端与波长转换器件的输入端之间形成折叠光路。光学组件位于机械定位装置中，并且机械定位装置沿着光学路径设置在基座模块上，使得半导体激光器的光束通过光学组件，被MEMS致动的反射镜反射回通过光学组件并进入波长转换装置的波导部分。 MEMS致动反射镜可操作以通过波长转换装置的输入来扫描半导体激光束的光束。光学组件可以利用机械定位装置沿光学路径调节，以将光束聚焦到波长转换装置的波导部分中。

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