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1. 发明申请

US20060155324A1 Vaso-occlusive devices with attached polymer structures 审中-公开
标题翻译：具有连接聚合物结构的血管闭塞装置
公开(公告)号：US20060155324A1
公开(公告)日：2006-07-13
申请号：US11034893
申请日：2005-01-12
申请人： Stephen Porter , Like Que , Jimmy Dao , Shana Castelli , Richard Murphy
发明人： Stephen Porter , Like Que , Jimmy Dao , Shana Castelli , Richard Murphy
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12145 , A61B17/1215 , A61B2017/00004 , A61B2017/12054 , A61B2017/12063 , D03D13/004
摘要： Disclosed herein are vaso-occlusive devices for forming occluding the vasculature of a patient. More particularly, disclosed herein are vaso-occlusive devices comprising at least one polymer structure and methods of making and using these devices.
摘要翻译：本文公开了用于形成阻塞患者脉管系统的血管闭塞装置。更具体地，本文公开了包含至少一种聚合物结构的血管闭塞装置以及制造和使用这些装置的方法。

2. 发明申请

US20110118776A1 DELIVERY WIRE ASSEMBLY FOR OCCLUSIVE DEVICE DELIVERY SYSTEM 审中-公开
标题翻译：交付设备传送系统的交付线组件
公开(公告)号：US20110118776A1
公开(公告)日：2011-05-19
申请号：US12945210
申请日：2010-11-12
申请人： Hancun Chen , Richard Murphy , Shana Castelli
发明人： Hancun Chen , Richard Murphy , Shana Castelli
IPC分类号： A61F2/01
CPC分类号： A61B17/12022 , A61B17/12031 , A61B17/12109 , A61B17/12145 , A61B17/1215 , A61B2017/00292 , A61B2017/00734 , A61B2017/12063
摘要： A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature, the assembly having a distal end portion comprising a proximal rigid segment, a distal rigid segment, and a flexible segment disposed between the proximal and distal rigid segments. The assembly also has a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen. A plug is seated in the conduit lumen and secured to an interior surface of the delivery wire conduit. A core wire is disposed in the conduit lumen and having a distal end extending through the plug, so that the plug secures the core wire to the delivery wire conduit. The plug may form a substantially fluid tight seal of the conduit lumen.
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件，所述组件具有包括近端刚性段，远侧刚性段和设置在近端和远端刚性段之间的柔性段的远端部分。组件还具有输送线导管，其具有联接到远端线圈部分的近端管状部分，相应的管状部分和线圈部分限定导管腔。塞子位于导管管腔中并固定到输送线管道的内表面。芯线设置在导管管腔中并且具有延伸穿过插塞的远端，使得插头将芯线固定到输送线导管。塞子可以形成导管管腔的基本上流体密封的密封。

3. 发明申请

US20110213405A1 VASO-OCCLUSIVE DEVICES WITH ATTACHED POLYMER STRUCTURES 审中-公开
标题翻译：具有连接聚合物结构的VASO-OCCLUSIVE设备
公开(公告)号：US20110213405A1
公开(公告)日：2011-09-01
申请号：US13102956
申请日：2011-05-06
申请人： Stephen Christopher Porter , Like Que , Jimmy D. Dao , Shana B. Castelli , Richard Murphy , Nestor Aganon , Lilibeth S. Camins
发明人： Stephen Christopher Porter , Like Que , Jimmy D. Dao , Shana B. Castelli , Richard Murphy , Nestor Aganon , Lilibeth S. Camins
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12145 , A61B17/1215 , A61B2017/00004 , A61B2017/12054 , A61B2017/12063 , D03D13/004
摘要： Disclosed herein are vaso-occlusive devices for forming occluding the vasculature of a patient. More particularly, disclosed herein are vaso-occlusive devices comprising at least one polymer structure and methods of making and using these devices.
摘要翻译：本文公开了用于形成阻塞患者脉管系统的血管闭塞装置。更具体地，本文公开了包含至少一种聚合物结构的血管闭塞装置以及制造和使用这些装置的方法。

4. 发明申请

US20100268252A1 ELECTRICAL CONTACT FOR OCCLUSIVE DEVICE DELIVERY SYSTEM 有权
标题翻译：电气设备输送系统的电气接触
公开(公告)号：US20100268252A1
公开(公告)日：2010-10-21
申请号：US12758528
申请日：2010-04-12
申请人： Hancun Chen , Lantao Guo , Jimmy Dao , Justin Vo , Michael Williams , Richard Murphy
发明人： Hancun Chen , Lantao Guo , Jimmy Dao , Justin Vo , Michael Williams , Richard Murphy
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12145 , A61B17/1215 , A61B2017/12063
摘要： A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen. A core wire is disposed in the conduit lumen and having a distal end coupled to an occlusive device, wherein an elongate electrical contact body at least partially seated in the conduit lumen and coupled to a proximal end of the core wire, the electrical contact body and the proximal tubular portion forming a junction. A coil collar is disposed around the electrical contact body near the junction
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件包括输送线导管，其具有联接到远端线圈部分的近端管状部分，相应的管状部分和线圈部分限定导管腔。芯线布置在导管管腔中并且具有联接到闭塞装置的远端，其中细长电接触体至少部分地位于导管管腔中并且联接到芯线的近端，电接触体和近端管状部分形成结。在接头附近的电接触体周围设置线圈套圈

5. 发明申请

US20100256666A1 DELIVERY WIRE FOR OCCLUSIVE DEVICE DELIVERY SYSTEM 审中-公开
标题翻译：用于交付设备传送系统的交付线
公开(公告)号：US20100256666A1
公开(公告)日：2010-10-07
申请号：US12752914
申请日：2010-04-01
申请人： Hancun Chen , Jimmy Dao , Richard Murphy
发明人： Hancun Chen , Jimmy Dao , Richard Murphy
IPC分类号： A61M29/00
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12109 , A61B17/1214 , A61B17/12145 , A61B17/1215 , A61B90/39 , A61B2017/12063 , A61B2017/12068 , A61M2025/09133 , A61M2025/0915
摘要： A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion connected to a distal coil portion, and a conduit lumen extending through the proximal tubular portion and the distal coil portion. The delivery wire assembly also includes a core wire disposed in the conduit lumen and having a distal end coupled to an occlusive device. The distal coil portion of the delivery wire assembly includes a plurality of zones and the plurality of zones decrease in stiffness distally along the length of the distal coil portion of the delivery wire assembly.
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件包括输送线导管，其具有连接到远侧线圈部分的近端管状部分和延伸穿过近端管状部分和远端线圈部分的管腔。输送线组件还包括设置在导管管腔中并且具有联接到闭塞装置的远端的芯线。输送线组件的远端线圈部分包括多个区域，并且多个区域沿着输送线组件的远端线圈部分的长度向远侧减小。

6. 发明授权

US08398671B2 Electrical contact for occlusive device delivery system 有权
标题翻译：闭塞装置输送系统的电气接触
公开(公告)号：US08398671B2
公开(公告)日：2013-03-19
申请号：US12758528
申请日：2010-04-12
申请人： Hancun Chen , Lantao Guo , Jimmy Dao , Justin Vo , Michael Williams , Richard Murphy
发明人： Hancun Chen , Lantao Guo , Jimmy Dao , Justin Vo , Michael Williams , Richard Murphy
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12145 , A61B17/1215 , A61B2017/12063
摘要： A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen. A core wire is disposed in the conduit lumen and having a distal end coupled to an occlusive device, wherein an elongate electrical contact body at least partially seated in the conduit lumen and coupled to a proximal end of the core wire, the electrical contact body and the proximal tubular portion forming a junction. A coil collar is disposed around the electrical contact body near the junction.
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件包括输送线导管，其具有联接到远端线圈部分的近端管状部分，相应的管状部分和线圈部分限定导管腔。芯线布置在导管管腔中并且具有联接到闭塞装置的远端，其中细长电接触体至少部分地位于导管管腔中并且联接到芯线的近端，电接触体和近端管状部分形成结。在接头附近的电接触体周围设置线圈套圈。

7. 发明申请

US20100268251A1 DELIVERY WIRE FOR OCCLUSIVE DEVICE DELIVERY SYSTEM AND METHOD OF MANUFACTURE 审中-公开
标题翻译：用于交付设备传送系统的交付线及其制造方法
公开(公告)号：US20100268251A1
公开(公告)日：2010-10-21
申请号：US12757886
申请日：2010-04-09
申请人： Hancun Chen , Jimmy Dao , Richard Murphy
发明人： Hancun Chen , Jimmy Dao , Richard Murphy
IPC分类号： A61B17/12 , B23P11/00
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12145 , A61B17/1215 , A61B2017/12063 , Y10T29/49826
摘要： A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen, a plug at least partially seated in the conduit lumen and coupled to an interior surface of the coil portion so as to form a substantially fluid tight seal of the conduit lumen, and a core wire disposed in the conduit lumen, the core wire having a distal end extending through the plug and coupled to an occlusive device
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件包括输送线导管，其具有联接到远端线圈部分的近端管状部分，相应的管状部分和线圈部分限定导管管腔，塞子至少部分地位于导管管腔中并联接到线圈部分的内表面，以便形成导管管腔的基本上流体密封的密封，以及设置在导管管腔中的芯线，芯线具有延伸穿过插塞的远端并耦合到闭塞装置

8. 发明授权

US09186149B2 Vaso-occlusive device 有权
标题翻译：血管闭塞装置
公开(公告)号：US09186149B2
公开(公告)日：2015-11-17
申请号：US13271453
申请日：2011-10-12
申请人： Hancun Chen , Richard Murphy , Jimmy Dao
发明人： Hancun Chen , Richard Murphy , Jimmy Dao
IPC分类号： A61M29/00 , A61B17/12
CPC分类号： A61B17/12145 , A61B17/12031 , A61B17/12109 , A61B17/1215 , A61B17/1219 , A61B2017/12054 , A61B2017/12063
摘要： A vaso-occlusive device includes an inner coil made from inner coil wire having a first diameter and formed from a first material, and an outer coil disposed at least partially around the inner coil and made from outer coil wire having a second diameter and formed from a second material. The inner coil has a first pitch and the outer coil has a second pitch. The first diameter, material, and pitch are different from the second diameter, material, and pitch, respectively. The outer coil defines a lumen and the inner coil is disposed at least partially in the lumen. The vaso-occlusive device also includes an intermediate layer disposed between the inner coil and the outer coil, where the intermediate layer includes a biocompatible metal or a biocompatible, swellable polymer.
摘要翻译：一种血管闭塞装置，包括由具有第一直径并由第一材料形成的内部线圈线制成的内部线圈，以及至少部分地围绕所述内部线圈设置并由具有第二直径的外部线圈线制成的外部线圈，第二种材料。内部线圈具有第一间距，外部线圈具有第二间距。第一直径，材料和间距分别与第二直径，材料和间距不同。外部线圈限定内腔，并且内部线圈至少部分地设置在内腔中。血管闭塞装置还包括设置在内部线圈和外部线圈之间的中间层，其中中间层包括生物相容性金属或生物相容的可溶胀聚合物。

9. 发明申请

US20120089174A1 VASO-OCCLUSIVE DEVICE 有权
标题翻译： VASO-OCCLUSIVE设备
公开(公告)号：US20120089174A1
公开(公告)日：2012-04-12
申请号：US13271453
申请日：2011-10-12
申请人： Hancun Chen , Richard Murphy , Jimmy Dao
发明人： Hancun Chen , Richard Murphy , Jimmy Dao
IPC分类号： A61F2/01
CPC分类号： A61B17/12145 , A61B17/12031 , A61B17/12109 , A61B17/1215 , A61B17/1219 , A61B2017/12054 , A61B2017/12063
摘要： A vaso-occlusive device includes an inner coil made from inner coil wire having a first diameter and formed from a first material, and an outer coil disposed at least partially around the inner coil and made from outer coil wire having a second diameter and formed from a second material. The inner coil has a first pitch and the outer coil has a second pitch. The first diameter, material, and pitch are different from the second diameter, material, and pitch, respectively. The outer coil defines a lumen and the inner coil is disposed at least partially in the lumen. The vaso-occlusive device also includes an intermediate layer disposed between the inner coil and the outer coil, where the intermediate layer includes a biocompatible metal or a biocompatible, swellable polymer.
摘要翻译：一种血管闭塞装置，包括由具有第一直径并由第一材料形成的内部线圈线制成的内部线圈，以及至少部分地围绕所述内部线圈设置并由具有第二直径的外部线圈线制成的外部线圈，第二种材料。内部线圈具有第一间距，外部线圈具有第二间距。第一直径，材料和间距分别与第二直径，材料和间距不同。外部线圈限定内腔，并且内部线圈至少部分地设置在内腔中。血管闭塞装置还包括设置在内部线圈和外部线圈之间的中间层，其中中间层包括生物相容性金属或生物相容的可溶胀聚合物。

10. 发明申请

US20110118772A1 DELIVERY WIRE ASSEMBLY FOR OCCLUSIVE DEVICE DELIVERY SYSTEM 审中-公开
标题翻译：交付设备传送系统的交付线组件
公开(公告)号：US20110118772A1
公开(公告)日：2011-05-19
申请号：US12944254
申请日：2010-11-11
申请人： Hancun Chen , Richard Murphy , Jimmy Dao
发明人： Hancun Chen , Richard Murphy , Jimmy Dao
IPC分类号： A61B17/00
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61B2017/0088 , A61B2017/12063 , A61B2018/00083
摘要： A core wire of a delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature, includes a wire having a polyimide coating, with a polymer jacket disposed around the polyimide coating, and a hypotube disposed around the polymer jacket. The delivery wire assembly further comprises a delivery wire conduit including a coil disposed around the wire, wherein a proximal end of the coil is connected to a distal end of the hypotube. The polyimide coating may be enhanced with a nano-particle or micro-fiber ceramic, such as yttria-stabilized zirconia.
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件的芯线包括具有聚酰亚胺涂层的线，聚酰亚胺涂层周围设置聚合物护套，以及设置在聚合物护套周围的海波管。输送线组件还包括输送线导管，其包括设置在线周围的线圈，其中线圈的近端连接到海波管的远端。聚酰亚胺涂层可以用纳米颗粒或微纤维陶瓷如氧化钇稳定的氧化锆来增强。

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