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    • 1. 发明授权
    • Guide and position monitor for invasive medical instrument
    • 侵入性医疗器械导向和位置监测仪
    • US06695786B2
    • 2004-02-24
    • US10100649
    • 2002-03-18
    • Shih-Ping WangShengtz LinSiqing ZhangDonald ChinKaren D. Maroc
    • Shih-Ping WangShengtz LinSiqing ZhangDonald ChinKaren D. Maroc
    • A61B814
    • A61B8/0841A61B8/0833A61B8/587A61B17/3403A61B34/72A61B90/50A61B2017/3405A61B2017/3411A61B2017/3413
    • An instrument guide is described for mounting an invasive instrument such as a biopsy needle to an imaging probe, controlling its position, monitoring its position, and/or predictively displaying its position on a user display of the medical imaging system. A plurality of substantially rigid segments are hingeably connected to the probe, to an instrument handle, and to each other such that movement of the biopsy needle is restricted to within the imaged plane. However, substantial freedom of movement within the imaged plane is provided such that the instrument may be inserted into the patient over a wide range of angles. In one preferred embodiment, angle detectors are provided at each segment intersection and measurements provided for computing and displaying the instrument position and orientation on the user display. The instrument guide/position monitor is preferably made with low-cost components such that it is disposable after a single use. A predictive user display is provided in which the throw of a spring-loaded instrument is shown on the user display, the throw corresponding to the space that the instrument will occupy after a spring trigger is activated.
    • 描述了用于将诸如活检针的入侵器械安装到成像探针,控制其位置,监视其位置和/或预测性地在医疗成像系统的用户显示器上显示其位置的仪器指南。 多个基本上刚性的部分可铰接地连接到探针,仪器把手和彼此,使得活检针的运动被限制在成像平面内。 然而,提供成像平面内的实质运动自由度,使得仪器可以在宽范围的角度上插入到患者体内。 在一个优选实施例中,角度检测器设置在每个段交叉点处,并且提供用于在用户显示器上计算和显示仪器位置和姿态的测量结果。 仪器导向/位置监视器优选地由低成本部件制成,使得它在一次使用之后是一次性的。 提供了一种预测用户显示,其中在用户显示器上显示弹簧加载的仪器的投掷,对应于在弹簧触发器被激活之后仪器将占据的空间的投掷。
    • 2. 发明授权
    • Method and system for recording probe position during breast ultrasound scan
    • 用于在乳房超声扫描期间记录探头位置的方法和系统
    • US06675038B2
    • 2004-01-06
    • US09854654
    • 2001-05-14
    • Tommy Earl CupplesDonald ChinKaren D. Maroc
    • Tommy Earl CupplesDonald ChinKaren D. Maroc
    • A61B505
    • A61B8/467A61B8/0825A61B8/4245A61B8/4405A61B8/463A61B8/465A61B8/468
    • A method, system, and computer program product for providing textual ultrasound probe position information corresponding to an ultrasound image of a target is described. Based on a user's graphical manipulations of a probe icon relative to a breast icon, a text sequence corresponding to the user's estimate of the position of an ultrasound probe is automatically generated. User error and fatigue are reduced because manual keying of the probe position text sequence is no longer required, and the resulting outputs are standardized in format and therefore more amenable to archiving and electronic analysis. In one preferred embodiment, the user is permitted to select a snapping mode of operation in which the probe icon is snapped to align with a major direction of a preselected coordinate system, further enhancing ease-of-use and reducing user fatigue.
    • 描述了用于提供与目标的超声波图像相对应的文本超声探针位置信息的方法,系统和计算机程序产品。 基于用户相对于乳房图标的探针图标的图形操作,自动生成与用户对超声波探头的位置的估计相对应的文本序列。 用户错误和疲劳减少,因为不再需要手动键入探针位置文本序列,并且所得到的输出格式被标准化,因此更适合归档和电子分析。 在一个优选实施例中,允许用户选择捕捉操作模式,其中探针图标被卡扣以与预选坐标系的主要方向对齐,进一步增强易用性并减少用户疲劳。
    • 3. 发明申请
    • ADJUNCTIVE ULTRASOUND PROCESSING AND DISPLAY FOR BREAST CANCER SCREENING
    • 用于乳腺癌筛查的ADJUNCTIVE ULTRASOUND PROCESSING AND DISPLAY FOR BREAST CANCER SCREENING
    • US20130289405A1
    • 2013-10-31
    • US13863259
    • 2013-04-15
    • Shih-Ping WANGDonald ChinFangyi RaoNico Karssemeijier
    • Shih-Ping WANGDonald ChinFangyi RaoNico Karssemeijier
    • A61B8/08
    • A61B8/5215A61B6/463A61B6/502A61B6/5241A61B6/5247A61B6/563A61B8/0825A61B8/406A61B8/4281A61B8/4405A61B8/463A61B8/464A61B8/465A61B8/466A61B8/467A61B8/5238A61B8/565G06F19/00
    • An adjunctive ultrasound mammography system and associated methods use an adjunctive ultrasound display configured for quick, intuitive, interactive viewing of volumetric ultrasound scans, displayed near a conventional x-ray mammogram display. Preferred navigations among a thick-slice image array, a selected enlarged thick-slice image, and planar ultrasound views are described, including a mode in which the planar ultrasound views are updated in real time as a cursor is moved across an active thick-slice image. In one example the thick-slice images are inverted prior to display, with non-breast areas of the image preferably segmented out and reset to dark. The inverted thick-slice images are of more familiar significance to radiologists as they are more like conventional x-ray mammograms and allow benign features to be more easily dismissed as compared to non-inverted thick-slice images. Preferred embodiments emphasize larger mass lesions and that compensate for mass lesions that straddle thick-slice region borders.
    • 辅助超声乳腺摄影系统和相关方法使用辅助超声显示器来配置用于快速,直观,互动地观看体积超声扫描,显示在常规x射线乳腺X线照片显示附近。 描述了厚切片图像阵列,所选放大的厚片图像和平面超声波视图之间的优选导航,包括当光标移动穿过有源厚片时实时更新平面超声波视图的模式 图片。 在一个示例中,厚片图像在显示之前被反转,图像的非乳房区域优选地被分割出并且重置为暗。 倒置的厚片图像对于放射科医师来说更为重要,因为它们更像是常规的x射线乳房X线照相术,并且与非倒置的厚切片图像相比,允许良性特征更容易被消除。 优选实施例强调较大的质量损伤并且补偿跨越厚片区域边界的质量损伤。
    • 4. 发明申请
    • ADJUNCTIVE ULTRASOUND PROCESSING AND DISPLAY FOR BREAST CANCER SCREENING
    • 用于乳腺癌筛查的ADJUNCTIVE ULTRASOUND PROCESSING AND DISPLAY FOR BREAST CANCER SCREENING
    • US20090312640A1
    • 2009-12-17
    • US12546339
    • 2009-08-24
    • Shih-Ping WangDonald ChinFangyi RaoNico Karssemeijier
    • Shih-Ping WangDonald ChinFangyi RaoNico Karssemeijier
    • A61B8/14G06K9/00A61B6/04
    • A61B8/5215A61B6/463A61B6/502A61B6/5241A61B6/5247A61B6/563A61B8/0825A61B8/406A61B8/4281A61B8/4405A61B8/463A61B8/464A61B8/465A61B8/466A61B8/467A61B8/5238A61B8/565
    • An adjunctive ultrasound mammography system and associated methods are described comprising an adjunctive ultrasound display configured for quick, intuitive, interactive viewing of data derived from volumetric ultrasound scans, the data being displayed near a conventional x-ray mammogram display. Preferred embodiments for navigating among a thick-slice image array, a selected enlarged thick-slice image, and planar ultrasound views are described, including a preferred embodiment in which the planar ultrasound views are updated in real time as a cursor is moved across an active thick-slice image. In one preferred embodiment the thick-slice images are inverted prior to display, with non-breast areas of the image preferably segmented out and reset to dark. The inverted thick-slice images are of more familiar significance to radiologists having years of expertise in analyzing conventional x-ray mammograms. For example, the inverted thick-slice images allow benign features to be more easily dismissed as compared to non-inverted thick-slice images. Preferred embodiments for computing thick-slice image values from the volumetric scan data are also described that emphasize larger mass lesions in the resulting thick-slice images, and that compensate for mass lesions that straddle thick-slice region borders.
    • 描述了一种辅助超声乳腺摄影系统和相关方法,其包括辅助性超声显示器,其配置用于快速,直观,互动地观看从体积超声扫描获得的数据,该数据显示在常规x射线乳房X线照片显示附近。 描述了用于在厚片图像阵列,选定的放大的厚片图像和平面超声波视图之间导航的优选实施例,包括优选实施例,其中当光标跨越活动的时候,平面超声波视图被实时地更新 厚片图像。 在一个优选实施例中,厚片图像在显示之前被反转,其中图像的非乳房区域优选地被分割出并且重新设置为暗。 倒置的厚片图像对于在分析常规x射线乳房X线照片方面具有多年专业知识的放射科医师更为重要。 例如,与非倒置厚片图像相比,反向厚片图像允许更容易地解除良性特征。 还描述了用于从体积扫描数据计算厚片图像值的优选实施例,其强调所得厚片图像中的较大质量损伤,并补偿跨越厚片区域边界的质量损伤。
    • 5. 发明申请
    • BREAST CANCER SCREENING WITH ADJUNCTIVE ULTRASOUND MAMMOGRAPHY
    • 乳腺癌筛查与ADJUNCTIVE超声波手术
    • US20090240150A1
    • 2009-09-24
    • US12479468
    • 2009-06-05
    • Shih-Ping WANGDonald ChinFangyi Rao
    • Shih-Ping WANGDonald ChinFangyi Rao
    • A61B8/14
    • A61B6/463A61B6/4423A61B6/502A61B6/5247A61B6/563A61B8/0825A61B8/406A61B8/462A61B8/463A61B8/464A61B8/465A61B8/467A61B8/469A61B8/5238A61B8/565G06F19/00
    • An adjunctive ultrasound mammography system and associated methods are described, comprising a scanning apparatus for facilitating standardized, repeatable breast ultrasound scans, and further comprising an adjunctive ultrasound display apparatus configured for fast, intuitive viewing of adjunctive ultrasound data concurrently with x-ray mammogram information. In one preferred embodiment, thick-slice ultrasound images are displayed near an x-ray mammogram such that a screening radiologist can quickly view the thick-slice images for assistance in interpreting the x-ray mammogram. Methods for concurrently acquiring and displaying vibrational resonance image (VDI) data are described. Computer-aided diagnosis (CAD) algorithms that incorporate acoustically-based feature vectors are described, the feature vectors including lateral shadow metrics, vertical shadow metrics, posterior enhancement metrics, and VDI-based metrics. Algorithms are also described that combine x-ray mammogram CAD results with adjunctive ultrasound CAD results without requiring complex image registrations therebetween. Many of the practical, economic, and political barriers to acceptance and integration of ultrasound mammography into existing mass breast cancer screening environments are mitigated.
    • 描述了辅助超声乳腺摄影系统和相关方法,其包括用于促进标准化,可重复的乳房超声扫描的扫描装置,并且还包括辅助超声显示装置,其配置为与X射线乳腺X线照相信息同时快速,直观地观看辅助超声数据。 在一个优选实施例中,在x射线乳房X线照片附近显示厚片超声图像,使得筛选放射科医师可以快速查看厚切片图像以辅助解释X射线乳腺X线照片。 描述了同时获取和显示振动共振图像(VDI)数据的方法。 描述了包含声学特征向量的计算机辅助诊断(CAD)算法,其特征向量包括横向阴影度量,垂直阴影度量,后验增强度量和基于VDI的度量。 还描述了将x射线乳房X线照片CAD结果与辅助超声CAD结果相结合的算法,而不需要它们之间的复杂图像注册。 超声乳房X线照相术在现有的大规模乳腺癌筛查环境中接受和整合的许多实际,经济和政治障碍得到缓解。
    • 6. 发明授权
    • Breast cancer screening with adjunctive ultrasound mammography
    • 乳腺癌筛查与辅助超声乳房X线照相术
    • US07828732B2
    • 2010-11-09
    • US12479468
    • 2009-06-05
    • Shih-Ping WangDonald ChinFangyi Rao
    • Shih-Ping WangDonald ChinFangyi Rao
    • A61B8/00
    • A61B6/463A61B6/4423A61B6/502A61B6/5247A61B6/563A61B8/0825A61B8/406A61B8/462A61B8/463A61B8/464A61B8/465A61B8/467A61B8/469A61B8/5238A61B8/565G06F19/00
    • An adjunctive ultrasound mammography system and associated methods are described, comprising a scanning apparatus for facilitating standardized, repeatable breast ultrasound scans, and further comprising an adjunctive ultrasound display apparatus configured for fast, intuitive viewing of adjunctive ultrasound data concurrently with x-ray mammogram information. In one preferred embodiment, thick-slice ultrasound images are displayed near an x-ray mammogram such that a screening radiologist can quickly view the thick-slice images for assistance in interpreting the x-ray mammogram. Methods for concurrently acquiring and displaying vibrational resonance image (VDI) data are described. Computer-aided diagnosis (CAD) algorithms that incorporate acoustically-based feature vectors are described, the feature vectors including lateral shadow metrics, vertical shadow metrics, posterior enhancement metrics, and VDI-based metrics. Algorithms are also described that combine x-ray mammogram CAD results with adjunctive ultrasound CAD results without requiring complex image registrations therebetween. Many of the practical, economic, and political barriers to acceptance and integration of ultrasound mammography into existing mass breast cancer screening environments are mitigated.
    • 描述了辅助超声乳腺摄影系统和相关方法,其包括用于促进标准化,可重复的乳房超声扫描的扫描装置,并且还包括辅助超声显示装置,其配置为与X射线乳腺X线照相信息同时快速,直观地观看辅助超声数据。 在一个优选实施例中,在x射线乳房X线照片附近显示厚片超声图像,使得筛选放射科医师可以快速查看厚切片图像以辅助解释X射线乳腺X线照片。 描述了同时获取和显示振动共振图像(VDI)数据的方法。 描述了包含声学特征向量的计算机辅助诊断(CAD)算法,其特征向量包括横向阴影度量,垂直阴影度量,后验增强度量和基于VDI的度量。 还描述了将x射线乳房X线照片CAD结果与辅助超声CAD结果相结合的算法,而不需要它们之间的复杂图像注册。 超声乳房X线照相术在现有的大规模乳腺癌筛查环境中接受和整合的许多实际,经济和政治障碍得到缓解。
    • 7. 发明授权
    • Adjunctive ultrasound processing and display for breast cancer screening
    • 辅助超声处理和显示乳腺癌筛查
    • US07597663B2
    • 2009-10-06
    • US10305936
    • 2002-11-27
    • Shih-Ping WangDonald ChinFangyi RaoNico Karssemeijier
    • Shih-Ping WangDonald ChinFangyi RaoNico Karssemeijier
    • A61B8/00
    • A61B8/5215A61B6/463A61B6/502A61B6/5241A61B6/5247A61B6/563A61B8/0825A61B8/406A61B8/4281A61B8/4405A61B8/463A61B8/464A61B8/465A61B8/466A61B8/467A61B8/5238A61B8/565G06F19/00
    • An adjunctive ultrasound mammography system and associated methods are described comprising an adjunctive ultrasound display configured for quick, intuitive, interactive viewing of data derived from volumetric ultrasound scans, the data being displayed near a conventional x-ray mammogram display. Preferred embodiments for navigating among a thick-slice image array, a selected enlarged thick-slice image, and planar ultrasound views are described, including a preferred embodiment in which the planar ultrasound views are updated in real time as a cursor is moved across an active thick-slice image. In one preferred embodiment the thick-slice images are inverted prior to display, with non-breast areas of the image preferably segmented out and reset to dark. The inverted thick-slice images are of more familiar significance to radiologists having years of expertise in analyzing conventional x-ray mammograms. For example, the inverted thick-slice images allow benign features to be more easily dismissed as compared to non-inverted thick-slice images. Preferred embodiments for computing thick-slice image values from the volumetric scan data are also described that emphasize larger mass lesions in the resulting thick-slice images, and that compensate for mass lesions that straddle thick-slice region borders.
    • 描述了一种辅助超声乳腺摄影系统和相关方法,其包括辅助性超声显示器,其配置用于快速,直观,互动地观看从体积超声扫描获得的数据,该数据显示在常规x射线乳房X线照片显示附近。 描述了用于在厚片图像阵列,选定的放大的厚片图像和平面超声波视图之间导航的优选实施例,包括优选实施例,其中当光标移动到活动的时候,平面超声波视图被实时地更新 厚片图像。 在一个优选实施例中,厚片图像在显示之前被反转,其中图像的非乳房区域优选地被分割出并且重新设置为暗。 倒置的厚片图像对于在分析常规x射线乳房X线照片方面具有多年专业知识的放射科医师更为重要。 例如,与非倒置厚片图像相比,反向厚片图像允许更容易地解除良性特征。 还描述了用于从体积扫描数据计算厚片图像值的优选实施例,其强调所得厚片图像中的较大质量损伤,并补偿跨越厚片区域边界的质量损伤。
    • 9. 发明授权
    • Endocardial mapping system and method
    • 心内膜测绘系统及方法
    • US5813991A
    • 1998-09-29
    • US842942
    • 1997-04-25
    • N. Parker WillisMarsha HurdDonald Chin
    • N. Parker WillisMarsha HurdDonald Chin
    • A61N1/37A61B55/04
    • A61N1/37
    • Endocardial system and method in which noise and artifacts introduced by a simulator are decoupled from a recorder by connecting the stimulator to the electrodes used for pacing and recording only when it is necessary to do so. At other times, the stimulator is disconnected, and low level signals are recorded without interference from the stimulator. In one embodiment, the stimulator is connected only during the time the pacing pulse is being delivered. In another, a stimulator which delivers pacing pulses in response to intrinsic activation of tissue at the pacing site is connected during delivery of a pacing pulse, disconnected during the measurement period which follows, and then reconnected so that it can sense further intrinsic activity and deliver another pacing pulse.
    • 通过将刺激器连接到仅用于起搏和记录的电极的情况下,通过将仿真器引入的噪声和伪像与记录器分离的心内膜系统和方法,仅在需要时才进行。 在其他时间,刺激器断开,低电平信号被记录而不受刺激器的干扰。 在一个实施例中,刺激器仅在起搏脉冲被输送的时间期间连接。 另一方面,响应于起搏部位的组织的内在活化而产生起搏脉冲的刺激器在递送起搏脉冲期间连接,在随后的测量期间断开连接,然后重新连接,使得其可以感测到进一步的内在活动和递送 另一个起搏脉冲。