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1. 发明申请

US20060073584A1 Chemical analyzing apparatus 审中-公开
标题翻译：化学分析仪
公开(公告)号：US20060073584A1
公开(公告)日：2006-04-06
申请号：US11239231
申请日：2005-09-30
申请人： Shigeyuki Sasaki , Yoshihiro Nagaoka , Hirotoshi Ishimaru , Nobuyuki Maki , Toshiaki Yokobayashi , Michihiro Saito , Taisaku Seino
发明人： Shigeyuki Sasaki , Yoshihiro Nagaoka , Hirotoshi Ishimaru , Nobuyuki Maki , Toshiaki Yokobayashi , Michihiro Saito , Taisaku Seino
IPC分类号： C12M1/34
CPC分类号： B01L7/52 , B01L3/502715 , B01L3/502723 , B01L3/502753 , B01L2200/10 , B01L2200/16 , B01L2300/0654 , B01L2300/0816 , B01L2300/1822 , B01L2300/1844 , B01L2400/0406 , B01L2400/0409 , G01N2035/00356 , G01N2035/00495
摘要： A chemical analyzing apparatus accommodates therein a structure for retaining a sample and reagents. A detecting mechanism detects the sample after reaction with a reagent. After or during extraction of a biological substance from the sample in the structure, a temperature of a fluid in a space around the structure is controlled to a value which is suitable for enzyme.
摘要翻译：化学分析装置中容纳有用于保持样品和试剂的结构。检测机构在与试剂反应后检测样品。在从结构中的样品中提取生物物质之后或之后，结构周围空间中的流体的温度被控制为适合于酶的值。

2. 发明授权

US07678576B2 Chemical analysis apparatus and chemical analysis cartridge 有权
标题翻译：化学分析装置和化学分析盒
公开(公告)号：US07678576B2
公开(公告)日：2010-03-16
申请号：US11319680
申请日：2005-12-29
申请人： Shigeyuki Sasaki , Yoshihiro Nagaoka , Noriyo Nishijima , Naruo Watanabe , Michihiro Saito , Taisaku Seino , Satoshi Takahashi
发明人： Shigeyuki Sasaki , Yoshihiro Nagaoka , Noriyo Nishijima , Naruo Watanabe , Michihiro Saito , Taisaku Seino , Satoshi Takahashi
IPC分类号： G01N35/00 , B01F15/02
CPC分类号： B01F11/0071 , B01F13/0059 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/1816 , B01L2400/0409 , B01L2400/0442 , B01L2400/0475 , G01N21/0332 , G01N21/07 , G01N21/645 , G01N2021/0325 , G01N2035/00148 , G01N2035/00495 , G01N2035/00534 , Y10T436/111666
摘要： The invention provides a chemical analysis apparatus which easily agitates and warms up. A chemical analysis apparatus has a motor, a retaining disc which can be rotated by the motor, a plurality of inspection cartridges which are arranged on the retaining disc, a punching machine for punching the inspection cartridges, a warming apparatus and a detection apparatus. The inspection cartridge includes a container formed by a concave portion and a base plate having a flow path. A cover covering the container and the flow path is installed to the base plate. A liquid solution is moved to the container in an outer peripheral side with respect to a rotation axis from the container in an inner peripheral side with respect to the rotation axis via the flow path, by utilizing a centrifugal force generated on the basis of the rotation of the retaining disc. The inspection cartridge is provided with an agitating means for agitating the liquid solution within the container and a warming means for warming up the liquid solution within the container.
摘要翻译：本发明提供一种容易搅动和加热的化学分析装置。化学分析装置具有电动机，可由电动机旋转的保持盘，设置在保持盘上的多个检查筒，冲压检查筒的冲孔机，加温装置和检测装置。检查筒包括由凹部形成的容器和具有流路的基板。覆盖容器和流路的盖子安装在基板上。通过利用基于旋转产生的离心力，液体溶液在相对于旋转轴线的旋转轴线的相对于旋转轴线的内周侧的外周侧经由流路被移动到容器的保持盘。检查筒设置有用于搅拌容器内的液体溶液的搅拌装置和用于预热容器内的液体溶液的加温装置。

3. 发明申请

US20060159586A1 Chemical analysis apparatus and chemical analysis cartridge 有权
标题翻译：化学分析仪和化学分析盒
公开(公告)号：US20060159586A1
公开(公告)日：2006-07-20
申请号：US11319680
申请日：2005-12-29
申请人： Shigeyuki Sasaki , Yoshihiro Nagaoka , Noriyo Nishijima , Naruo Watanabe , Michihiro Saito , Taisaku Seino , Satoshi Takahashi
发明人： Shigeyuki Sasaki , Yoshihiro Nagaoka , Noriyo Nishijima , Naruo Watanabe , Michihiro Saito , Taisaku Seino , Satoshi Takahashi
IPC分类号： G01N31/22
CPC分类号： B01F11/0071 , B01F13/0059 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/1816 , B01L2400/0409 , B01L2400/0442 , B01L2400/0475 , G01N21/0332 , G01N21/07 , G01N21/645 , G01N2021/0325 , G01N2035/00148 , G01N2035/00495 , G01N2035/00534 , Y10T436/111666
摘要： The invention provides a chemical analysis apparatus which easily agitates and warms up. A chemical analysis apparatus has a motor, a retaining disc which can be rotated by the motor, a plurality of inspection cartridges which are arranged on the retaining disc, a punching machine for punching the inspection cartridges, a warming apparatus and a detection apparatus. The inspection cartridge includes a container formed by a concave portion and a base plate having a flow path. A cover covering the container and the flow path is installed to the base plate. A liquid solution is moved to the container in an outer peripheral side with respect to a rotation axis from the container in an inner peripheral side with respect to the rotation axis via the flow path, by utilizing a centrifugal force generated on the basis of the rotation of the retaining disc. The inspection cartridge is provided with an agitating means for agitating the liquid solution within the container and a warming means for warming up the liquid solution within the container.
摘要翻译：本发明提供一种容易搅动和加热的化学分析装置。化学分析装置具有电动机，可由电动机旋转的保持盘，设置在保持盘上的多个检查筒，冲压检查筒的冲孔机，加温装置和检测装置。检查筒包括由凹部形成的容器和具有流路的基板。覆盖容器和流路的盖子安装在基板上。通过利用基于旋转产生的离心力，液体溶液在相对于旋转轴线的旋转轴线的相对于旋转轴线的内周侧的外周侧经由流路被移动到容器的保持盘。检查筒设置有用于搅拌容器内的液体溶液的搅拌装置和用于预热容器内的液体溶液的加温装置。

4. 发明申请

US20090016931A1 CHEMICAL ANALYSIS DEVICE 审中-公开
标题翻译：化学分析装置
公开(公告)号：US20090016931A1
公开(公告)日：2009-01-15
申请号：US12169968
申请日：2008-07-09
申请人： Taisaku Seino , Hiroshi Umetsu , Michihiro Saito , Takayuki Kanda , Kumiko Hattori
发明人： Taisaku Seino , Hiroshi Umetsu , Michihiro Saito , Takayuki Kanda , Kumiko Hattori
IPC分类号： G01N35/10 , B01L3/02
CPC分类号： G01N35/10 , B01L3/502 , G01N2035/103 , G01N2035/1051 , G01N2035/1062
摘要： A chemical analysis device capable of suppressing deterioration of analysis and test accuracy while avoiding contamination by residual samples or reagents and having no complicated configuration is constructed.A pipetting unit is equipped with a syringe, plunger, and needle unit in which a carrier for capturing nucleic acid and a detection cell is mounted on the needle unit. A pipetting unit drive system is configured so that the pipetting unit is detachable. After the detection cell is removed from the pipetting unit and fixed to a nucleic acid amplification detection unit, a suction/dispensing operation of samples/reagents is performed by the pipetting unit and components to be measured are captured by the carrier. Captured components are measured after being dispensed into the detection cell fixed to the nucleic acid amplification detection unit. Then, the detection cell is taken out from the nucleic acid amplification detection unit while mounted on the pipetting unit and the whole pipetting unit is removed from the pipetting unit drive system.
摘要翻译：能够抑制分析和测试精度恶化的化学分析装置，同时避免残留的样品或试剂的污染并且没有复杂的结构。移液单元配备有注射器，柱塞和针单元，其中用于捕获核酸的载体和检测单元安装在针单元上。移液单元驱动系统被构造成使得移液单元可拆卸。在从移液单元取出检测单元并固定在核酸扩增检测单元上之后，通过移液单元进行样品/试剂的抽吸/分注操作，由载体捕获要测量的成分。在分配到固定在核酸扩增检测单元上的检测单元之后，测量捕获的成分。然后，在安装在移液单元上的情况下，从核酸扩增检测单元取出检测单元，从移液单元驱动系统中取出整个移液单元。

5. 发明授权

US5867607A Digital halftoning apparatus and method 失效
标题翻译：数字半色调装置及方法
公开(公告)号：US5867607A
公开(公告)日：1999-02-02
申请号：US617032
申请日：1996-03-18
申请人： Takeshi Shibuya , Tatsunari Satou , Taisaku Seino
发明人： Takeshi Shibuya , Tatsunari Satou , Taisaku Seino
IPC分类号： B41J2/52 , G06T5/00 , H04N1/405 , H04N1/52 , G06K9/38 , H04N1/40
CPC分类号： H04N1/52
摘要： A raster device such as a digital printer or the like which sequentially compares input image data with each element in a threshold matrix to convert the input image data into binary or multi-level pixel data. For providing both a higher resolution and a larger number of halftone levels for an output image at a low cost, an input image is decomposed into four color planes as CMYK data, and data on each color plane is compared with a dither matrix in a binarization circuit to be converted to binary data. The dither matrix generates a dither pattern composed of eight clusters having substantially the same shape as a kernel cluster capable of expressing 15 or more halftone levels. In this way, a smooth gradation having 120 or more halftone levels is realized by repetitively applying a small pattern having approximately 15 halftone levels.
摘要翻译：诸如数字打印机等的光栅装置顺序地将输入图像数据与阈值矩阵中的每个元素进行比较，以将输入图像数据转换为二进制或多级像素数据。为了以低成本为输出图像提供更高分辨率和更大数量的半色调水平，输入图像被分解成四个颜色平面作为CMYK数据，并且将每个颜色平面上的数据与二值化中的抖动矩阵进行比较电路转换为二进制数据。抖动矩阵产生由能够表达15个或更多半色调水平的核心簇具有基本相同形状的8个簇组成的抖动图案。以这种方式，通过重复施加具有大约15个半色调水平的小图案来实现具有120个或更多半色调水平的平滑等级。

6. 发明授权

US07309568B2 Method in inspecting DNA and apparatus therefor 有权
标题翻译：检查DNA及其仪器的方法
公开(公告)号：US07309568B2
公开(公告)日：2007-12-18
申请号：US10229204
申请日：2002-08-26
申请人： Yoshitada Oshida , Satoshi Takahashi , Kenji Yasuda , Taisaku Seino
发明人： Yoshitada Oshida , Satoshi Takahashi , Kenji Yasuda , Taisaku Seino
IPC分类号： C12Q1/68 , C12M1/00 , B32B5/02 , G01N21/00
CPC分类号： G01N21/6428 , G01J3/4406 , G01N21/6452
摘要： A method and apparatus of stably obtaining fluorescent images of two or more fluorescent samples includes disposing the samples onto compartments defined on a substrate. The compartments are sequentially irradiated with an exciting light where the intensity varies. A value of fluorescence as generated from each of the samples is determined, and a fluorescent image is obtained based on the value of fluorescence.
摘要翻译：稳定地获得两个或多个荧光样品的荧光图像的方法和装置包括将样品设置在限定在基底上的隔室上。这些隔室用强度变化的激发光依次照射。确定从每个样品产生的荧光值，并且基于荧光值获得荧光图像。

7. 发明授权

US5548411A Facsimile apparatus 失效
标题翻译：传真机
公开(公告)号：US5548411A
公开(公告)日：1996-08-20
申请号：US427279
申请日：1995-04-24
申请人： Kazutaka Sato , Michihiro Watanabe , Masahisa Aoyagi , Taisaku Seino , Katsuo Ohki , Hiromitsu Fukuda , Hideyuki Kawase , Kimio Oga , Akira Shimizu , Youichi Narui , Tsuguo Suzuki , Yasuo Otsuka , Kazutoshi Konno
发明人： Kazutaka Sato , Michihiro Watanabe , Masahisa Aoyagi , Taisaku Seino , Katsuo Ohki , Hiromitsu Fukuda , Hideyuki Kawase , Kimio Oga , Akira Shimizu , Youichi Narui , Tsuguo Suzuki , Yasuo Otsuka , Kazutoshi Konno
IPC分类号： H04N1/00 , H04N1/04
CPC分类号： H04N1/0057 , H04N1/00543
摘要： A facsimile apparatus has a lower structure and an upper structure which is swingable between a raised open position an a lowered close position about a pivot located at a lower part of the rear end portion of the apparatus. A thermal print head is fixed to the front end portion of the upper structure. A recording medium conveyor roller is fixed to the front end portion of the lower structure. A linear image sensor and an original sheet conveyor roller are fixed to a central portion of the lower structure. The recording medium is placed on the lower structure at a position between the thermal print head and the linear image sensor.
摘要翻译：传真装置具有下部结构和上部结构，所述上部结构可以在围绕位于所述装置的后端部分的下部的枢轴的升高的打开位置和降低的关闭位置之间摆动。热敏打印头固定到上部结构的前端部分。记录介质传送辊固定到下部结构的前端部分。线性图像传感器和原稿输送辊固定到下部结构的中心部分。记录介质在热打印头和线性图像传感器之间的位置处放置在下部结构上。

8. 发明申请

US20120183439A1 CHEMICAL ANALYZER 审中-公开
标题翻译：化学分析仪
公开(公告)号：US20120183439A1
公开(公告)日：2012-07-19
申请号：US13389974
申请日：2010-08-10
申请人： Taisaku Seino , Takenori Okusa
发明人： Taisaku Seino , Takenori Okusa
IPC分类号： G01N30/00
CPC分类号： G01N35/04
摘要： A chemical analyzer has a reaction vessel magazine 1 having multiple magazine cells 2 having an opening at each of its two ends that houses a reaction vessel 3, and the openings are sealed with protective films 4 and 5. A cutter 9 faces one of the openings of a magazine cell 2 so as to cut the protective film 5 of the magazine cell 2. Also, a pushrod 8 is provided in such a way as to face the other opening of the magazine cell 2 so as to push out the reaction vessel 3 placed inside the cell 2 through the other opening of the cell 2 that the cutter 9 faces. Thus, during removal of the reaction vessel 3 from the magazine cell 2, the antibody or antigen layer on the reaction vessel 3 can be prevented from being damaged.
摘要翻译：化学分析仪具有反应容器料盒1，反应容器料盒1具有多个料盒单元2，其两端各具有开口，容纳反应容器3，开口用保护膜4和5密封。切割器9面向其中一个开口以切断刀库单元2的保护膜5.此外，推杆8设置成面向刀库单元2的另一个开口以推出反应容器3 通过切割器9面对的单元2的另一个开口放置在单元2内。因此，在从盒式电池2移除反应容器3时，可以防止反应容器3上的抗体或抗原层被损坏。

9. 发明授权

US07217352B2 Capillary electrophoresis device 有权
标题翻译：毛细管电泳装置
公开(公告)号：US07217352B2
公开(公告)日：2007-05-15
申请号：US10446107
申请日：2003-05-28
申请人： Taisaku Seino , Tomoyuki Sakai , Miho Ozawa , Masaya Kojima , Eric S. Nordman
发明人： Taisaku Seino , Tomoyuki Sakai , Miho Ozawa , Masaya Kojima , Eric S. Nordman
IPC分类号： G01N27/26
CPC分类号： G01N27/44704 , G01N27/44782
摘要： An electrophoresis device is disclosed that is capable of reducing waves occurring in a fluid in which the capillary tips of a capillary assay are immersed. A plurality of partition plate members can be provided in a container containing the fluid to divide the surface of the fluid into several sections. The container can be transported at a high speed, and the capillary tips can be immersed in the fluid quickly, thereby preventing resolution degradation caused by a long period of exposure of the capillary tips to air. Throughput of sample analysis can also be improved because it is not necessary to wait until waves disappear before conducting an analysis.
摘要翻译：公开了一种电泳装置，其能够减少毛细管测定的毛细管尖端浸入其中的流体中发生的波。可以在容纳流体的容器中设置多个隔板构件，以将流体的表面分成若干部分。容器可以高速运输，并且毛细管尖端可以快速地浸入流体中，从而防止毛细管尖端长时间暴露于空气引起的分解降解。也可以提高样本分析的吞吐量，因为在进行分析之前不必等到波浪消失。

10. 发明授权

US5838465A Color compensating method of color image and color image generating apparatus 失效
标题翻译：彩色图像和彩色图像生成装置的颜色补偿方法
公开(公告)号：US5838465A
公开(公告)日：1998-11-17
申请号：US566108
申请日：1995-12-01
申请人： Tatsunari Satou , Taisaku Seino , Takeshi Shibuya
发明人： Tatsunari Satou , Taisaku Seino , Takeshi Shibuya
IPC分类号： G03F3/08 , H04N1/60 , G06K9/00
CPC分类号： H04N1/6033
摘要： A color correcting method for a color image generating apparatus for overlapping 3 or 4 color materials according to color image data of 3 separated colors of yellow (Y), magenta (M) and cyan (C) or of 4 separated colors of Y, M, C and black (K) to obtain a multicolor image, wherein the apparatus includes a color detector, a test pattern is printed in a vertical/horizontal stripe form of 2-color combinations of 2 of the 3 or 4 colors and is measured by the color detector to find a hue value, a relative overlap deviation of the colors Y, M, C or Y, M, C, K is calculated from the found hue value, and an irradiation start position of a semiconductor laser in a main-scan direction and an irradiation start position of the semiconductor laser in a feed direction are controlled to correct the relative overlap deviation. Or a color correcting method and apparatus in which a color correction coefficient or one of a plurality of color correction tables previously prepared for overlap deviations corresponding to the color drift is selected and set in color correcting means for color correction, or color drifts in a continuous print mode and in a non-continuous print mode are corrected.
摘要翻译：根据黄色（Y），品红色（M）和青色（C）的3种分离颜色的彩色图像数据或Y，M的4种分离颜色，重叠3或4种颜色材料的彩色图像产生装置的颜色校正方法，C和黑色（K），以获得多色图像，其中该装置包括颜色检测器，测试图案以3或4种颜色的2种2色组合的垂直/水平条纹形式印刷，并通过根据所发现的色调值计算颜色Y，M，C或Y，M，C，K的相对重叠偏差，以及主色调中的半导体激光器的照射开始位置，扫描方向和半导体激光器在进给方向的照射开始位置被控制以校正相对重叠偏差。或者颜色校正方法和装置，其中选择预先准备用于与颜色漂移相对应的重叠偏差的颜色校正系数或多个颜色校正表中的一个，并将其设置在用于颜色校正的颜色校正装置中，或者在连续的颜色校正装置中进行颜色漂移打印模式和非连续打印模式被更正。

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