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1. 发明申请

US20070123930A1 Embolic filtering devices 审中-公开
标题翻译：栓塞过滤装置
公开(公告)号：US20070123930A1
公开(公告)日：2007-05-31
申请号：US11652167
申请日：2007-01-11
申请人： Scott Huter , John Papp , Douglas Gesswein , Wayne Cornish , Peter D'Aquanni , Thomas Tokarchik , Andy Denison , Kevin Magrini , Benjamin Huter , Charles Peterson , William Boyle , Mark Richardson , Ryan Grandfield , Kathern Lind
发明人： Scott Huter , John Papp , Douglas Gesswein , Wayne Cornish , Peter D'Aquanni , Thomas Tokarchik , Andy Denison , Kevin Magrini , Benjamin Huter , Charles Peterson , William Boyle , Mark Richardson , Ryan Grandfield , Kathern Lind
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： An expandable frame for an embolic filtering device used to capture embolic debris in a body vessel includes a first half frame having a first control arm connected to a second control arm by a partial loop and a second half frame having a first control arm connected to a second control arm by a partial loop. The partial loops cooperatively form a composite loop for attachment of a filtering element which will expand in the body vessel to capture embolic debris entrained in the fluid of the vessel. The expandable frame and filtering element can be mounted on a filter support structure, such as a coiled wire, and mounted on a guide wire. The expandable frames includes an articulation region which helps to distribute the strain which can be developed when the frame moves between an expanded and deployed position. The expandable frame may include further strain distributing bends which help distribute strain and increase the bendability of the frame.
摘要翻译：用于捕获身体血管中的栓塞碎片的栓塞过滤装置的可膨胀框架包括：第一半框架，具有通过部分回路连接到第二控制臂的第一控制臂，以及具有连接到第二控制臂的第二控制臂的第二半框架第二控制臂通过部分回路。部分回路协同地形成用于附接过滤元件的复合回路，该过滤元件将在体内容器中膨胀以捕获携带在血管流体中的栓塞碎片。可膨胀框架和过滤元件可以安装在诸如线圈的过滤器支撑结构上，并且安装在导丝上。可扩展框架包括铰接区域，其有助于分布当框架在展开位置和展开位置之间移动时可展开的应变。可扩展框架可以包括进一步的应变分布弯曲，其有助于分布应变并增加框架的可弯曲性。

2. 发明申请

US20070167975A1 Embolic protection devices 有权
标题翻译：栓塞保护装置
公开(公告)号：US20070167975A1
公开(公告)日：2007-07-19
申请号：US11651667
申请日：2007-01-10
申请人： William Boyle , David Burkett , Andy Denison , Benjamin Huter , Scott Huter , Arkady Kokish , Kent Stalker , Chicheng Wang , John Whitfield
发明人： William Boyle , David Burkett , Andy Denison , Benjamin Huter , Scott Huter , Arkady Kokish , Kent Stalker , Chicheng Wang , John Whitfield
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61F2230/008
摘要： An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guidewire and is deployed within the patient's vasculature as the guidewire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature. Interventional devices can be delivered over the guidewire and any embolic debris created during the interventional procedure and released into the blood stream will enter the filtering assembly and be captured therein. Other embodiments include filtering assemblies attached to an outer tubular member and inner shaft member which apply axial force to the distal ends of the assembly to either expand or contract the struts as needed.
摘要翻译：一种用于血管中的栓塞保护装置，当在狭窄或闭塞区域进行介入手术以捕获可能在手术期间产生和释放到血流中的任何栓塞物质。该装置包括具有自扩张支柱组件和附接到其上的过滤元件的过滤组件。在一个实施例中，过滤组件附接到导丝的远端，并且当导线被操纵进入治疗区域时，其部署在患者的脉管系统内。以同轴布置放置在过滤组件上方的限制护套将过滤组件保持在其收缩位置，直到其准备好被医师部署为止。此后，护套可缩回以露出过滤组件，然后过滤组件将在患者的脉管系统内自我扩张。介入装置可以在导丝上传送，并且在介入手术期间产生的并释放到血流中的任何栓塞碎片将进入过滤组件并被捕获在其中。其他实施例包括附接到外部管状构件和内部轴构件的过滤构件，其向组件的远端施加轴向力，以根据需要来扩展或收缩支柱。

3. 发明申请

US20070208374A1 EMBOLIC PROTECTION DEVICES 审中-公开
标题翻译：嵌入式保护装置
公开(公告)号：US20070208374A1
公开(公告)日：2007-09-06
申请号：US11747459
申请日：2007-05-11
申请人： William Boyle , Andy Denison , Benjamin Huter , Scott Huter , Richard Stack , Kent Stalker , Christopher Tarapata , John Whitfield
发明人： William Boyle , Andy Denison , Benjamin Huter , Scott Huter , Richard Stack , Kent Stalker , Christopher Tarapata , John Whitfield
IPC分类号： A61F2/01 , A61M29/00
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guide wire and is deployed within the patient's vasculature as the guide wire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature. Interventional devices can be delivered over the guide wire and any embolic debris created during the interventional procedure and released into the blood stream will enter the filtering assembly and be captured therein. Other embodiments include filtering assemblies attached to an outer tubular member and inner shaft member which apply axial force to the distal ends of the assembly to either expand or contract the struts as needed.
摘要翻译：一种用于血管中的栓塞保护装置，当在狭窄或闭塞区域进行介入手术以捕获可能在手术期间产生和释放到血流中的任何栓塞物质。该装置包括具有自扩张支柱组件和附接到其上的过滤元件的过滤组件。在一个实施例中，过滤组件附接到导丝的远端，并且当导丝被操纵进入治疗区域时，其被布置在患者的脉管系统内。以同轴布置放置在过滤组件上方的限制护套将过滤组件保持在其收缩位置，直到其准备好由医师部署。此后，护套可缩回以露出过滤组件，然后过滤组件将在患者的脉管系统内自我扩张。介入装置可以在导丝上传送，并且在介入手术期间产生的并释放到血流中的任何栓塞碎片将进入过滤组件并被捕获在其中。其他实施例包括附接到外部管状构件和内部轴构件的过滤构件，其向组件的远端施加轴向力，以根据需要来扩展或收缩支柱。

4. 发明申请

US20050228439A1 Delivery and recovery system for embolic protection system 审中-公开
标题翻译：用于栓塞保护系统的交付和恢复系统
公开(公告)号：US20050228439A1
公开(公告)日：2005-10-13
申请号：US11139462
申请日：2005-05-26
申请人： Christopher Andrews , William Boyle , Sergio Correa , Andy Denison , Benjamin Huter , Scott Huter , Brad Jordan , Paul Muller , Paul Neale , Samir Patel , Richard Stack
发明人： Christopher Andrews , William Boyle , Sergio Correa , Andy Denison , Benjamin Huter , Scott Huter , Brad Jordan , Paul Muller , Paul Neale , Samir Patel , Richard Stack
IPC分类号： A61F2/01 , A61F2/06 , A61M29/00
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A system for enabling the insertion and removal of an embolic protection device, for capturing and retaining embolic debris which can be created during the performance of a therapeutic interventional procedure in a stenosed or occluded region of a blood vessel. The system, in an embodiment thereof, is capable of enabling at least one operator to control the delivery and removal of an embolic protection device to a position in a patient's vasculature distal to an interventional procedure site, to enable the exchange of the delivery and recovery system. The system, in another embodiment thereof, includes a delivery system and a recovery system which are capable of enabling the delivery and recovery of an embolic protection device so as to maintain a clinically acceptable profile and flexibility through the patient's vasculature.
摘要翻译：一种能够插入和移除栓塞保护装置的系统，用于捕获和保持在血管狭窄或阻塞区域中执行治疗性介入手术期间可产生的栓塞残留物。该系统在其一个实施例中能够使至少一个操作者能够将栓塞保护装置的输送和移除控制到远离介入手术部位的患者脉管系统中的位置，以实现交付和恢复的交换系统。该系统在其另一个实施例中包括输送系统和恢复系统，其能够实现栓塞保护装置的输送和恢复，以便通过患者的脉管系统保持临床可接受的特征和灵活性。

5. 发明申请

US20080091231A1 EXPANDABLE CAGES FOR EMBOLIC FILTERING DEVICES 审中-公开
标题翻译：用于嵌入式过滤装置的可扩展的纸张
公开(公告)号：US20080091231A1
公开(公告)日：2008-04-17
申请号：US11956990
申请日：2007-12-14
申请人： William Boyle , William Harrison , Benjamin Huter , Scott Huter , Paul Muller , John Papp
发明人： William Boyle , William Harrison , Benjamin Huter , Scott Huter , Paul Muller , John Papp
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： A self-expanding cage for use in conjunction with an embolic filtering device includes a circumferential member adapted to expand from an unexpanded position to a expanded position within the patient's body vessel. A proximal strut and distal strut are attached to the circumferential member to form the cage. A plurality of proximal and distal struts may be attached the circumferential member. Additionally, a second circumferential member can be attached to the first circumferential member. Each circumferential member can be connected by a single or a plurality of connecting struts. One embodiment of the cage utilizes a single wire to form to the cage. A delivery system attached to the single wire cage moves the cage and its associated filter element between the expanded and unexpanded positions through relative movement of the distal delivery system. This can be accomplished by either torquing the guide wire onto which the expandable cage is mounted or by longitudinally moving a tubular member which forms part of the delivery system longitudinally in relation to the guide wire.
摘要翻译：用于与栓塞过滤装置结合使用的自膨胀笼包括适于从未膨胀位置膨胀到患者体内容器内的扩张位置的周向构件。近端支柱和远侧支柱附接到周向构件以形成保持架。多个近端和远侧支柱可以附接在周向构件上。此外，第二周向构件可以附接到第一圆周构件。每个周向构件可以通过单个或多个连接支柱连接。笼的一个实施例使用单个线来形成笼。附接到单线笼的输送系统通过远端输送系统的相对运动使笼及其相关联的过滤元件在膨胀位置和未膨胀位置之间移动。这可以通过扭转其上安装有可膨胀笼的引导线或通过纵向移动相对于导丝纵向移动形成输送系统的一部分的管状构件来实现。

6. 发明申请

US20070250108A1 FLEXIBLE AND COMFORMABLE EMBOLIC FILTERING DEVICES 有权
标题翻译：柔性和可变的嵌入式滤波器件
公开(公告)号：US20070250108A1
公开(公告)日：2007-10-25
申请号：US11767784
申请日：2007-06-25
申请人： William Boyle , Benjamin Huter , Scott Huter , John Papp
发明人： William Boyle , Benjamin Huter , Scott Huter , John Papp
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/008
摘要： A self-expanding cage for use in conjunction with an embolic filtering device includes one or more circumferential members adapted to expand from an unexpanded position to a expanded position within the patient's body vessel. At least one proximal strut and at least one distal strut are attached to the circumferential member to form the basket. The circumferential member may include a plurality of bending regions which enhance the ability of the circumferential member to move between the unexpanded and expanded positions. The proximal and distal struts can be attached to one of the bending regions. When two or more circumferential members are utilized, each member may be connected by a connecting strut which may be connected at a bending region. The connecting strut can be a straight segment or may have a non-linear shape to provide additional flexibility. The expandable cage can be mounted to a elongated member, such as a guide wire, and can be either permanently mounted or rotatably mounted thereto.
摘要翻译：用于与栓塞过滤装置结合使用的自膨胀笼包括适于从未膨胀位置扩展到患者体内容器内的扩张位置的一个或多个周向构件。至少一个近端支柱和至少一个远端支柱附接到周向构件以形成篮。周向构件可以包括多个弯曲区域，这些弯曲区域增强了圆周构件在未膨胀和膨胀位置之间移动的能力。近端和远端支柱可以附接到一个弯曲区域。当使用两个或更多个周向构件时，每个构件可以通过可在弯曲区域处连接的连接支柱连接。连接支柱可以是直线段，或者可以具有非线性形状以提供额外的灵活性。可扩展的保持架可以安装到诸如导丝的细长构件上，并且可以永久地安装或可旋转地安装在其上。

7. 发明申请

US20050004595A1 Embolic filtering devices 有权
标题翻译：栓塞过滤装置
公开(公告)号：US20050004595A1
公开(公告)日：2005-01-06
申请号：US10675611
申请日：2003-09-29
申请人： William Boyle , John Papp , Charles Peterson , Paul Muller , Donald Schwarten , Kathern Lind
发明人： William Boyle , John Papp , Charles Peterson , Paul Muller , Donald Schwarten , Kathern Lind
IPC分类号： A61F2/01 , A61M25/06 , A61M29/00
CPC分类号： A61F2/013 , A61F2/97 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： An expandable frame for an embolic filtering device used to capture embolic debris in a body vessel includes a first half frame having a first control arm connected to a second control arm by a partial loop and a second half frame having a first control arm connected to a second control arm by a partial loop. The partial loops cooperatively form a composite loop for attachment of a filtering element which will expand in the body vessel to capture embolic debris entrained in the fluid of the vessel. The expandable frame and filtering element can be mounted on a filter support structure, such as a coiled wire, and mounted on a guide wire. The expandable frames include an articulation region which helps to distribute the strain which can be developed when the frame moves between an expanded and deployed position. The expandable frame may include further strain distributing bends which help distribute strain and increase the bendability of the frame. A modified torque device with extension arm prevents guide wire damage, prevents distal propagation of the peeling action and facilitates filter deployment during operation.
摘要翻译：用于捕获身体血管中的栓塞碎片的栓塞过滤装置的可膨胀框架包括：第一半框架，具有通过部分回路连接到第二控制臂的第一控制臂，以及具有连接到第二控制臂的第二控制臂的第二半框架第二控制臂通过部分回路。部分回路协同地形成用于附接过滤元件的复合回路，该过滤元件将在体内容器中膨胀以捕获携带在血管流体中的栓塞碎片。可膨胀框架和过滤元件可以安装在诸如线圈的过滤器支撑结构上，并且安装在导丝上。可扩展框架包括铰接区域，其有助于分布当框架在展开位置和展开位置之间移动时可展开的应变。可扩展框架可以包括进一步的应变分布弯曲，其有助于分布应变并增加框架的可弯曲性。具有延伸臂的改进的扭矩装置防止导丝损坏，防止剥离动作的远端传播，并且在操作期间有助于过滤器部署。

8. 发明申请

US20050182441A1 Embolic filtering devices for bifurcated vessels 有权
公开(公告)号：US20050182441A1
公开(公告)日：2005-08-18
申请号：US11108309
申请日：2005-04-18
申请人： Andy Denison , William Boyle
发明人： Andy Denison , William Boyle
IPC分类号： A61F2/01 , A61F2/06 , A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2002/065 , A61F2230/0008 , A61F2230/001 , A61F2230/008
摘要： An embolic filtering device for use in a bifurcated vessel includes delivery device having a first guide wire and a second guide wire. The second guide wire diverges from the distal-end region of the first guide wire. The filter device also includes a filter support having a first deployment member and a second deployment member. These deployment members can be formed as a first loop and a second loop. A bifurcated filter element is coupled to the filter support. The distal-end region of the first guide wire extends through a first leg of the filter element and the second guide wire extends through a second leg of the filter element. During use, the first leg of the filter element is deployed within a first branch of the bifurcated vessel and the second leg of the filter element is deployed within a second branch of the bifurcated vessel.

9. 发明申请

US20070167976A1 Support structures for embolic filtering devices 审中-公开
标题翻译：栓塞过滤装置的支撑结构
公开(公告)号：US20070167976A1
公开(公告)日：2007-07-19
申请号：US11698516
申请日：2007-01-25
申请人： William Boyle , John Papp , Francisco Sanchez , Steven Saville
发明人： William Boyle , John Papp , Francisco Sanchez , Steven Saville
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008 , A61M25/0014
摘要： An inner support structure for an embolic filtering device includes a tubular member having a first support region for supporting the proximal portion of a filter assembly and a second support region for supporting the distal portion of the filter assembly. The inner support structure facilitates rotation and restricts longitudinal movement of the embolic filtering device relative to a guide wire. Alternatively, the inner support structure includes a bushing coupled to the guide wire and a sleeve with a head on its proximal end positioned within a cavity in the bushing, thereby facilitating rotation and restricting longitudinal movement of the sleeve. The proximal portion of the filter assembly is supported on the sleeve. A sleeve for retaining the struts of an expandable cage of the embolic filtering device includes a central lumen for positioning the sleeve onto a guide wire and peripheral lumens for positioning and retaining the struts.
摘要翻译：用于栓塞过滤装置的内部支撑结构包括管状构件，其具有用于支撑过滤器组件的近侧部分的第一支撑区域和用于支撑过滤器组件的远端部分的第二支撑区域。内部支撑结构有助于旋转并且限制栓塞过滤装置相对于导丝的纵向移动。或者，内部支撑结构包括联接到导丝的衬套和套筒，其顶端位于其近端位于套管内的空腔内，从而有助于旋转并限制套筒的纵向移动。过滤器组件的近端部分被支撑在套筒上。用于保持栓塞过滤装置的可膨胀笼的支柱的套筒包括用于将套管定位在导丝和用于定位和保持支柱的外围腔的中央腔。

10. 发明申请

US20050075663A1 Offset proximal cage for embolic filtering devices 审中-公开
标题翻译：用于栓塞过滤装置的偏心近端笼
公开(公告)号：US20050075663A1
公开(公告)日：2005-04-07
申请号：US10954532
申请日：2004-09-30
申请人： William Boyle , John Papp
发明人： William Boyle , John Papp
IPC分类号： A61F2/01 , A61M29/00
CPC分类号： B82Y30/00 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0076 , A61F2230/008 , B82Y20/00
摘要： An expandable cage used in conjunction with an embolic filtering device has a strut configuration including a proximal strut assembly coupled to a distal strut assembly. A filter can be attached to the distal strut assembly which has an inlet opening. The proximal strut assembly is “offset” from the distal strut assembly in that these proximal struts extend substantially along the vessel wall of the patient, rather than being “centered” in the body vessel.,when the cage is expanded in a body vessel. As a result, there is little cage structure directly in front of the opening of the filter, resulting in a virtually unobstructed opening for the filter.
摘要翻译：与栓塞过滤装置结合使用的可膨胀笼具有支柱构造，其包括联接到远侧支柱组件的近侧支柱组件。过滤器可以连接到具有入口开口的远端支柱组件。近端支柱组件与远侧支柱组件“偏移”，因为这些近端支柱基本上沿着患者的血管壁延伸，而不是在体腔中被“中心”延伸。结果，直接在过滤器开口的前方存在很少的笼结构，导致过滤器几乎无障碍地打开。

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