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1. 发明申请

WO2009069086A3 COMPOSITE MATERIALS INCLUDING AN INTRINSICALLY CONDUCTING POLYMER, AND METHODS AND DEVICES 审中-公开
公开(公告)号：WO2009069086A3
公开(公告)日：2009-06-04
申请号：PCT/IB2008/054967
申请日：2008-11-26
申请人： STRÖMME, Maria , NYHOLM, Leif , MIHRANYAN, Albert
发明人： STRÖMME, Maria , NYHOLM, Leif , MIHRANYAN, Albert
IPC分类号： H01B1/12
摘要： A composite material in the form of a continuous structure comprises an intrinsically conducting polymer (ICP) layer coated on a substrate, the composite material having a surface area of at least 0.1 m 2 /g, at least 1 m 2 /g, or at least 5 m 2 /g. Methods of manufacturing the composite material comprise coating the substrate with a layer of the intrinsically conducting polymer. Electrochemical or electrical devices comprise at least one component formed of the composite material.

2. 发明申请

WO2007066222A1 CELLULOSE GEL FORMULATIONS 审中-公开
标题翻译：纤维素凝胶制剂
公开(公告)号：WO2007066222A1
公开(公告)日：2007-06-14
申请号：PCT/IB2006/003571
申请日：2006-12-06
申请人： MIHRANYAN, Albert , STRÖMME, Maria
发明人： MIHRANYAN, Albert , STRÖMME, Maria
IPC分类号： C08L1/02 , A61L27/20 , C08J3/12
CPC分类号： C08L5/00 , A23L29/262 , A23L33/24 , A61K8/042 , A61K8/63 , A61K8/731 , A61K8/9706 , A61K9/0014 , A61K47/38 , A61L27/20 , A61Q19/00 , C08J3/122 , C08J2301/02 , C08L1/02 , C08L1/286 , C08L5/04 , C08L2666/26
摘要： The invention relates to dispersible cellulose powder compositions comprising non-seed cellulose powder derived from algae, fungi or tunicates, which compositions are useful in a variety of products such as food products, pharmaceuticals, cosmetics, paints, biocompatible materials for artificial tissue engineering and implantable biomaterials and relates to methods for preparing non-seed cellulose powder compositions.
摘要翻译：本发明涉及包含衍生自藻类，真菌或衣壳的非种子纤维素粉末的可分散纤维素粉末组合物，该组合物可用于各种产品，例如食品，药物，化妆品，油漆，用于人造组织工程的生物相容性材料和可植入生物材料，涉及制备非种子纤维素粉末组合物的方法。

3. 发明申请

WO2010029517A1 VINYL ALCOHOL CO-POLYMER CRYOGELS, VINYL ALCOHOL CO-POLYMERS, AND METHODS AND PRODUCTS THEREOF 审中-公开
标题翻译：乙烯醇共聚物聚合物，乙烯醇共聚物及其制备方法
公开(公告)号：WO2010029517A1
公开(公告)日：2010-03-18
申请号：PCT/IB2009/054012
申请日：2009-09-14
申请人： STRÖMME, Maria , MIHRANYAN, Albert
发明人： STRÖMME, Maria , MIHRANYAN, Albert
IPC分类号： C08F8/12 , C08F218/08 , A61K9/00
CPC分类号： A61L27/16 , A61K9/0014 , A61K9/0024 , A61K9/0031 , A61K9/006 , A61K9/0065 , A61K9/06 , A61K9/19 , A61K9/7007 , A61K47/34 , A61L27/52 , C08F8/12 , C08F218/08 , C08F220/06 , C08F220/56 , C08J5/18 , C08L29/04
摘要： A cryogel-forming vinyl alcohol co-polymer is operable to form a cryogel, i.e., a hydrogel formed by crytropic gelation, in an aqueous solution at a concentration of less than about 10% by weight, in the absence of a chemical cross-linking agent and in the absence of an emulsifier. In one embodiment, a vinyl alcohol co-polymer cryogel comprises at least about 75% by weight water and a vinyl alcohol co-polymer, wherein the vinyl alcohol co-polymer is operable to form a cryogel in an aqueous solution at a concentration of less than about 10% by weight, in the absence of a chemical cross-linking agent and in the absence of an emulsifier. In another embodiment, a vinyl alcohol co-polymer cryogel comprises at least abut 75% by weight water and a vinyl alcohol co-polymer comprising a saponified product of a vinyl acetate co- polymer formed from at least about 80% by weight of vinyl acetate monomer, and (i) at least about 3% by weight of acrylamide monomer or a mixture of acrylamide monomer and acrylic acid monomer, or (ii) at least about 5% by weight acrylic acid monomer. The vinyl acetate co- polymer, vinyl alcohol co-polymer and vinyl alcohol co-polymer cryogel may be formed according to particular methods, and the vinyl alcohol co-polymer cryogels may be used in various applications including biomedical implants and thin films and for delivery of therapeutic or cosmetic agents.
摘要翻译：低温凝胶形成乙烯醇共聚物可操作以在不存在化学交联的情况下，以小于约10重量％的浓度在水溶液中形成冷冻凝胶，即通过热溶胶凝胶形成的水凝胶并且在不存在乳化剂的情况下。在一个实施方案中，乙烯醇共聚物冷冻凝胶包含至少约75重量％的水和乙烯醇共聚物，其中乙烯醇共聚物可操作以在浓度较低的水溶液中形成冷冻凝胶在不存在化学交联剂的情况下和在不存在乳化剂的情况下。在另一个实施方案中，乙烯醇共聚物冷冻凝胶包含至少约75重量％的水和包含由至少约80重量％的乙酸乙烯酯形成的乙酸乙烯酯共聚物的皂化产物的乙烯醇共聚物单体，和（i）至少约3重量％的丙烯酰胺单体或丙烯酰胺单体和丙烯酸单体的混合物，或（ii）至少约5重量％的丙烯酸单体。可以根据具体方法形成乙酸乙烯酯共聚物，乙烯醇共聚物和乙烯醇共聚物冷冻凝胶，并且乙烯醇共聚物冷冻凝胶可用于各种应用，包括生物医学植入物和薄膜并用于递送的治疗或化妆品。

4. 发明申请

WO2006061716A1 PHARMACEUTICAL FORMULATION COMPRISING LOW CRYSTALLINITY CELLULOSE 审中-公开
标题翻译：包含低结晶性纤维素的药物制剂
公开(公告)号：WO2006061716A1
公开(公告)日：2006-06-15
申请号：PCT/IB2005/003806
申请日：2005-12-09
申请人： EK, Ragnar , STRÖMME, Maria , MIHRANYAN, Albert
发明人： EK, Ragnar , STRÖMME, Maria , MIHRANYAN, Albert
IPC分类号： A61K9/20 , A61K9/16 , A61K31/616
CPC分类号： A61K47/38 , A61K9/1652 , A61K9/2054 , A61K31/616
摘要： A pharmaceutical composition comprises a pharmaceutically effective amount of an active ingredient and low crystallinity cellulose having a crystallinity index of less than about 75% as measured by X-ray diffraction. The compositions advantageously may be provided in tablet form or granulate form and provide good stability against moisture degradation.
摘要翻译：药物组合物包含药学有效量的通过X射线衍射测量的结晶度指数小于约75％的活性成分和低结晶度纤维素。组合物有利地可以片剂形式或颗粒形式提供，并提供对水分降解的良好稳定性。

5. 发明申请

WO2016146188A1 CELLULOSE NANOFIBER MEMBRANE, ITS PREPARATION AND ITS USE 审中-公开
标题翻译：纤维素纳米纤维膜，其制备及其用途
公开(公告)号：WO2016146188A1
公开(公告)日：2016-09-22
申请号：PCT/EP2015/055708
申请日：2015-03-18
申请人： MIHRANYAN, Albert
发明人： MIHRANYAN, Albert
IPC分类号： B01D67/00 , B01D69/02 , B01D71/10 , D21H17/02 , D21H25/04 , D21H11/18 , D21H21/52
CPC分类号： B01D71/10 , B01D67/0004 , B01D67/0083 , B01D67/009 , B01D69/02 , B01D2323/283 , B01D2323/30 , D21H11/18 , D21H17/02 , D21H21/52 , D21H25/04
摘要： A filtration membrane comprising cellulose fibres, the membrane having a pore size distribution such that the modal pore diameter is between 10nm and 25nm and/or wherein less than 5% of the pore volume comprises pores of greater than 40nm and having a total porosity greater than 30%.
摘要翻译：一种包含纤维素纤维的过滤膜，所述膜的孔径分布使得模态孔径在10nm和25nm之间和/或其中小于5％的孔体积包含大于40nm的孔，并且具有大于 30％。

6. 发明申请

WO2017216584A1 NEW COMPOSITIONS 审中-公开
标题翻译：新组合物
公开(公告)号：WO2017216584A1
公开(公告)日：2017-12-21
申请号：PCT/GB2017/051782
申请日：2017-06-19
申请人： MIHRANYAN, Albert
发明人： MIHRANYAN, Albert
IPC分类号： A61K9/16 , A61K9/20 , A61K47/38 , C08L1/02
CPC分类号： A61K9/2054 , A61K9/1652 , A61K47/38 , C08L1/02
摘要： There is provided a pharmaceutical composition comprising a modified microcrystalline cellulose excipient and an active pharmaceutical ingredient (e.g. from the Type 2 or 4 BCS class), wherein the modified microcrystalline cellulose excipient has a relatively high5 surface area. Compositions of the invention find particularly utility as formulations comprising BCS Type 2 and 4 drugs, including NSAIDs or other drugs, that may be employed in the treatment of migraine and dysmenorrhea, as well as formulations comprising other poorly soluble active ingredients where rapid release in vivo is advantageous.
摘要翻译：提供了包含改性微晶纤维素赋形剂和活性药物成分（例如来自2型或4型BCS类）的药物组合物，其中改性微晶纤维素赋形剂具有相对高的表面积。本发明的组合物特别适用于包含可用于治疗偏头痛和痛经的包含BCS 2型和4型药物（包括NSAID或其它药物）的制剂，以及包含其他难溶性活性成分的制剂，其中体内快速释放是有利的。

7. 发明申请

WO2017137762A1 NEW COMPOSITIONS 审中-公开
标题翻译：新组合物
公开(公告)号：WO2017137762A1
公开(公告)日：2017-08-17
申请号：PCT/GB2017/050345
申请日：2017-02-10
申请人： MIHRANYAN, Albert
发明人： MIHRANYAN, Albert
IPC分类号： A61K9/14 , A61K31/192
CPC分类号： A61K9/146 , A61K31/192 , A61K31/196 , A61K31/405 , A61K31/5415 , A61K31/565
摘要： There is provided a pharmaceutical composition comprising cellulose obtained from algae, or a derivative of said cellulose, and an active pharmaceutical ingredient (e.g. from Type 2 and 4 BCS class), wherein the active pharmaceutical ingredient is in a predominantly amorphous form. Compositions of the invention find particularly utility as formulations comprising BCS Type 2 and 4 drugs, including NSAIDs or other drugs, that may be employed in the treatment of migraine or dysmenorrhea, as well as formulations comprising other poorly soluble active ingredients where rapid release in vivo is advantageous.
摘要翻译：提供了一种药物组合物，其包含从藻类或所述纤维素的衍生物和活性药物成分（例如2型和4型BCS类）获得的纤维素，其中活性药物成分在主要是无定形形式。本发明的组合物特别适用于包含可用于治疗偏头痛或痛经的包含BCS 2型和4型药物（包括NSAID或其他药物）的制剂，以及包含其他难溶性活性成分的制剂，其中体内快速释放是有利的。

8. 发明申请

WO2015101786A1 PROCESSES FOR THE PREPARATION OF CELLULOSE BEADS BY REACTION OF A CELLULOSE SUBSTRATE WITH AN OXIDANT 审中-公开
标题翻译：通过反应含有氧化物的纤维素基质制备纤维素珠粒的方法
公开(公告)号：WO2015101786A1
公开(公告)日：2015-07-09
申请号：PCT/GB2014/053855
申请日：2014-12-30
申请人： LINDH, Jonas , MIHRANYAN, Albert
发明人： LINDH, Jonas , MIHRANYAN, Albert
IPC分类号： C08B15/02 , C08L1/04 , C08J3/12 , C08J3/14
CPC分类号： C08B15/02 , C08L1/04 , C08L2205/18
摘要： There is provided a process for the preparation of cellulose beads comprising the step of reacting a cellulose substrate with an oxidant.
摘要翻译：提供了一种制备纤维素珠粒的方法，包括使纤维素底物与氧化剂反应的步骤。

9. 发明申请

WO2005023227A2 NICOTINE FORMULATIONS AND USE THEREOF 审中-公开
标题翻译： NICOTINE制剂及其用途
公开(公告)号：WO2005023227A2
公开(公告)日：2005-03-17
申请号：PCT/IB2004/002787
申请日：2004-08-27
申请人： PFIZER HEALTH AB , EK, Bo, Ragnar , MIHRANYAN, Albert , ANDERSSON, Sven-Börje , BOSSON, Bengt, Ake , LINDBERG, Nils-Olof
发明人： EK, Bo, Ragnar , MIHRANYAN, Albert , ANDERSSON, Sven-Börje , BOSSON, Bengt, Ake , LINDBERG, Nils-Olof
IPC分类号： A61K9/22
CPC分类号： A61K9/0075 , A61K9/0056 , A61K9/0058 , A61K9/006 , A61K9/146 , A61K9/7053 , A61K9/7084 , A61K31/4439 , A61K31/465
摘要： Nicotine-containing pharmaceutical compositions wherein nicotine is absorbed into and/or adsorbed onto cellulose of non-seed organism origin, especially cellulose from algae, bacteria and/or fungi. Use of such compositions in therapy.
摘要翻译：含尼古丁的药物组合物，其中尼古丁被吸收到非种子生物来源的纤维素上和/或吸附，特别是来自藻类，细菌和/或真菌的纤维素。在治疗中使用这些组合物。

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