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1. 发明申请

WO2014012996A1 DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置
公开(公告)号：WO2014012996A1
公开(公告)日：2014-01-23
申请号：PCT/EP2013/065130
申请日：2013-07-17
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： HARMS, Michael , HOFMANN, Verena , ROBERTS, Gareth , WARD, Chris , WILSON, Graham
IPC分类号： A61M5/32
CPC分类号： A61M5/3272 , A61M5/3204 , A61M5/326 , A61M5/3287 , A61M5/46 , A61M2005/3247 , A61M2005/3267 , A61M2205/582 , A61M2205/583 , A61M2205/586
摘要： The invention relates to a drug delivery device (1) for setting and dispensing a dose of a drug, comprising: • - a support body (2) having a first end defining a first opening and a second end defining a second opening, the support body (2) configured to retain a syringe barrel (5) sealed by a stopper (7) slidably disposed therein along an axial direction and adapted to have an integrated needle (6) or to be coupled with a needle assembly, • - a needle shield (4) adapted to be coupled to one of the ends of the support body (2), slidably disposed thereon and keyed to the support body (2) for preventing relative rotation, wherein at least one guiding track (2.3) is defined on the support body (2) and at least one retaining clip (4.5) arranged on the needle shield (4) is deflectable by the guiding track (2.3), wherein the guiding track (2.3) is configured such that the retaining clip (4.5) follows a first path when the needle shield (4) is depressed from an extended position to a retracted position for needle extension and that the retaining clip (4.5) follows a different second path when the needle shield (4) is subsequently extended, wherein a non-return catch (2.3.4) is arranged for catching the retaining clip (4.5) at the end of the second path.
摘要翻译：本发明涉及一种用于设置和分配药物剂量的药物输送装置（1），包括： - 支撑体（2），其具有限定第一开口的第一端和限定第二开口的第二端，所述支撑体（2）构造成保持由可滑动地设置在其中的止动件（7）密封的注射器筒（5）轴向并且适于具有一体的针（6）或与针组件联接。 - 适于联接到所述支撑体（2）的一个端部的针护罩（4），其可滑动地设置在其上并且键合到所述支撑体（2）以防止相对旋转，其中至少一个导轨（2.3）被限定在所述支撑体（2）上，并且布置在所述针护罩（4）上的至少一个保持夹（4.5）可被所述导轨（2.3）偏转，其中所述导轨（2.3）被构造成使得所述保持夹当针护罩（4）从延伸位置压缩到用于针伸出的缩回位置时，（4,5）遵循第一路径，并且当针护罩（4）随后延伸时，保持夹（4.5）遵循不同的第二路径，其中布置有止回夹（2.3.4），用于在第二路径的末端捕捉固定夹（4.5）。

2. 发明申请

WO2014012994A1 DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置
公开(公告)号：WO2014012994A1
公开(公告)日：2014-01-23
申请号：PCT/EP2013/065128
申请日：2013-07-17
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： HARMS, Michael , HOFMANN, Verena , ROBERTS, Gareth , WARD, Chris , WILSON, Graham
IPC分类号： A61M5/32
CPC分类号： A61M5/3271 , A61M5/3135 , A61M5/3204 , A61M5/3232 , A61M5/3245 , A61M5/3257 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M5/46 , A61M2005/3247 , A61M2005/3267 , A61M2205/582 , A61M2205/583 , A61M2205/586
摘要： The invention relates to a drug delivery device (1) for setting and dispensing a dose of a drug, comprising: a support body (2) having a first end defining a first opening and a second end defining a second opening and a centered outer indicator ring (2.2), a syringe barrel (5) sealed by a stopper (7) slidably disposed therein along an axial direction and adapted to have an integrated needle (6) or to be coupled with a needle assembly, wherein the syringe barrel (5) is positioned within the support body (2), a needle shield (4) adapted to be coupled to one of the ends of the support body (2) and slidably disposed thereon;, an outer body (3) adapted to be coupled to the other end of the support body (2) and slidably disposed thereon;, wherein the outer indicator ring (2.2) limits the movement of the outer body (3) as well as of the needle shield (4).
摘要翻译：本发明涉及一种用于设置和分配药物剂量的药物输送装置（1），包括：支撑体（2），其具有限定第一开口的第一端和限定第二开口的第二端和中心的外指示器环（2.2），注射器筒（5），其通过沿轴向方向可滑动地设置在其中的适于具有整体针（6）或与针组件联接的止动件（7）密封，其中注射器筒）定位在所述支撑体（2）内，针护罩（4）适于联接到所述支撑体（2）的一个端部并且可滑动地设置在其上;外主体（3），适于联接到支撑体（2）的另一端并可滑动地设置在其上，其中外指示环（2.2）限制了外主体（3）以及针护罩（4）的移动。

3. 发明申请

WO2012093070A1 A SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND AN INJECTION DEVICE 审中-公开
标题翻译：一种用于预充填的注射器和注射装置的安全装置
公开(公告)号：WO2012093070A1
公开(公告)日：2012-07-12
申请号：PCT/EP2011/074275
申请日：2011-12-30
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , EKMAN, Matthew
发明人： ROBERTS, Gareth , EKMAN, Matthew
IPC分类号： A61M5/20 , A61M5/32
CPC分类号： A61M5/3234 , A61M5/3202 , A61M5/3243 , A61M5/3257 , A61M5/326 , A61M2005/3241 , A61M2005/3267
摘要： A safety device(1) for a pre-filled syringe (2) is proposed that comprises -a hollow support body (1.2) with a helical groove (1.2.2) formed into an inner surface thereof, -a mounting collar (1.4) for mounting the pre-filled syringe (2) to the support body (1.2), -a spinning collar (1.5) with a helical tongue (1.5.2) formed to an outer surface thereof and -a torsion spring(1.6). The helical groove (1.2.2) accommodates the helical tongue (1.5.2). Upon release, the torsion spring (1.6) is capable of exerting a torque upon the spinning collar (1.5) which causes the spinning collar(1.5) to rotate within the support body(1.2). The engagement of the helical groove (1.2.2) and the helical tongue (1.5.2) redirects the rotational movement of the spinning collar (1.5) to a translatory movement that moves the mounting collar (1.4) in a proximal direction.
摘要翻译：提出了一种用于预填充注射器（2）的安全装置（1），其包括：具有形成在其内表面中的螺旋槽（1.2.2）的中空支撑体（1.2）， - 安装套环（1.4）用于将预填充的注射器（2）安装到支撑体（1.2）上， - 具有形成在其外表面上的螺旋舌（1.5.2）的旋转轴环（1.5）和 - 扭力弹簧（1.6）。螺旋槽（1.2.2）容纳螺旋舌（1.5.2）。释放后，扭转弹簧（1.6）能够在旋转轴环（1.5）上施加扭矩，这使得旋转轴环（1.5）在支撑体（1.2）内旋转。螺旋槽（1.2.2）和螺旋舌（1.5.2）的接合将旋转轴环（1.5）的旋转运动重定向到使得安装套环（1.4）沿近端方向移动的平移运动。

4. 发明申请

WO2012093069A1 ADAPTOR MEANS FOR USE IN COMBINATION WITH A PRE-FILLED SYRINGE AND A SAFETY DEVICE, SAFETY DEVICE AND INJECTION DEVICE 审中-公开
标题翻译：适用于与预充填的注射器和安全装置，安全装置和注射装置组合使用的装置
公开(公告)号：WO2012093069A1
公开(公告)日：2012-07-12
申请号：PCT/EP2011/074274
申请日：2011-12-30
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
发明人： ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
IPC分类号： A61M5/32 , A61M5/28
CPC分类号： A61M5/3243 , A61M5/28 , A61M5/326 , A61M5/3271 , A61M2005/3247
摘要： According to the invention, an adaptor means (1) for use in combination with a pre-filled syringe (2) and a safety device (3) for the pre-filled syringe (2) is adapted to affix the pre-filled syringe (2) thereto, whereby the adaptor means (1) engages a barrel (2.1) of the pre-filled syringe (2). The adaptor means (1) comprises at least one locking projection (1.1.1) that is adapted to lock the adaptor means (1) to the safety device (3).
摘要翻译：根据本发明，用于与预填充注射器（2）和预填充注射器（2）的安全装置（3）组合使用的适配器装置（1）适于将预先填充的注射器 2），由此适配器装置（1）接合预填充注射器（2）的筒体（2.1）。适配器装置（1）包括适于将适配器装置（1）锁定到安全装置（3）的至少一个锁定突起（1.1.1）。

5. 发明申请

WO2015078866A1 BOOT REMOVER 审中-公开
公开(公告)号：WO2015078866A1
公开(公告)日：2015-06-04
申请号：PCT/EP2014/075555
申请日：2014-11-25
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： WARD, Chris , ROBERTS, Gareth , WILSON, Graham , BAKER, Troy
IPC分类号： A61M5/32 , A61M5/00
CPC分类号： A61M5/3204 , A61M5/002 , A61M5/3202 , A61M5/3257 , A61M5/326 , A61M2005/3125 , A61M2005/3247 , A61M2005/3267
摘要： The invention relates to a boot remover (10) for removing a protective needle boot (11) from a drug delivery device (1), wherein the boot remover (10) is substantially sleeve shaped with an internal diameter and a length adapted to receive and substantially cover a needle shield (4), wherein the boot remover (10) is arranged to engage the protective needle boot (11) when attached to the drug delivery device (1). Furthermore, the invention relates to a drug delivery device (1) comprising a boot remover (10).
摘要翻译：本发明涉及一种用于从药物输送装置（1）移除保护针罩（11）的靴子去除器（10），其中靴子去除器（10）基本上是套筒形的，其内径和长度适于接收和基本上覆盖针护罩（4），其中所述护罩移除器（10）被布置成在附接到药物输送装置（1）时接合保护针罩（11）。此外，本发明涉及一种药物输送装置（1），其包括靴子去除器（10）。

6. 发明申请

WO2013037743A1 SAFETY DEVICE AND INJECTION DEVICE 审中-公开
标题翻译：安全装置和注射装置
公开(公告)号：WO2013037743A1
公开(公告)日：2013-03-21
申请号：PCT/EP2012/067688
申请日：2012-09-11
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , EKMAN, Matthew , SMITH, Christopher James , BAKER, Troy , WILSON, Graham , ROBERTS, Gareth , TUCKER, Carl
发明人： EKMAN, Matthew , SMITH, Christopher James , BAKER, Troy , WILSON, Graham , ROBERTS, Gareth , TUCKER, Carl
IPC分类号： A61M5/50 , A61M5/32 , A61M5/28
CPC分类号： A61M5/326 , A61M5/28 , A61M2005/3247
摘要： According to the invention, a safety device suitable (S) for a pre-filled syringe (2) containing a medicament comprises - a chassis (3) adapted to be affixed to the pre-filled syringe (2), - a deformable flexible outer structure (4) made from a material with a shape memory and - a substantially cylindrical needle shield (5) affixed or integral to the outer structure (4). The deformed flexible outer structure (4) is capable of advancing the needle shield (5) with respect to the chassis (3) in a distal direction (D) into a position in which the needle shield (5) projects from the chassis (3) in the distal direction (D). A biasing force for advancing the needle shield (5) originates from a shape memory effect that causes the deformed flexible outer structure (4) to substantially return to its unstressed shape.
摘要翻译：根据本发明，适用于包含药物的预填充注射器（2）的安全装置（S）包括 - 适于固定到预填充注射器（2）的底架（3）， - 可变形的柔性外部结构（4）由具有形状记忆的材料制成，以及 - 固定或与外部结构（4）成一体的大致圆柱形的针护罩（5）。变形的柔性外部结构（4）能够使针罩（5）相对于底架（3）沿远端方向（D）前进到针罩（5）从底架（3）突出的位置）在远端方向（D）。用于使针护罩（5）前进的偏压力来自形状记忆效应，其使得变形的柔性外部结构（4）基本上恢复到其不受应力的形状。

7. 发明申请

WO2012000834A1 SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND INJECTION DEVICE 审中-公开
标题翻译：一种预填充注射器和注射装置的安全装置
公开(公告)号：WO2012000834A1
公开(公告)日：2012-01-05
申请号：PCT/EP2011/060318
申请日：2011-06-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
发明人： ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
IPC分类号： A61M5/32
CPC分类号： A61M5/3271 , A61M5/28 , A61M5/3213 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M2005/3267
摘要： A safety device (1) for a pre-filled syringe (2) comprises a hollow support body (1.2) to retain the pre-filled syringe (2) therein,a hollow needle shield (1.1) that is slidable relative to the support body (1.2)and guiding means for guiding the movement of the needle shield (1.1.) relative to the support body (1.2).The guiding means comprise a deflectable flexible arm (1.1.4), a guide pin (1.1.3) and a guide track (1.2.2). The deflectable flexible arm extends essentially parallel to a central axis (A) of the safety device (1). The guide pin (1.1.3) extends radial from the flexible arm (1.1.4). The guide track (1.2.2) guides the guide pin (1.1.3) within and along the guide track (1.2.2) when the needle shield (1.1) is slid relative to the support body (1.2).
摘要翻译：用于预填充注射器（2）的安全装置（1）包括用于将预填充注射器（2）保持在其中的中空支撑体（1.2），可相对于支撑体滑动的中空针护罩（1.1）（1.2）和用于引导针护罩（1.1）相对于支撑体（1.2）的运动的引导装置。引导装置包括可偏转的柔性臂（1.1.4），引导销（1.1.3）和导轨（1.2.2）。可偏转的柔性臂基本上平行于安全装置（1）的中心轴线（A）延伸。导向销（1.1.3）从柔性臂（1.1.4）径向延伸。当针护罩（1.1）相对于支撑体（1.2）滑动时，导轨（1.2.2）将引导销（1.1.3）引导到引导轨道（1.2.2）内和沿导轨（1.2.2）。

8. 发明申请

WO2012093072A1 A SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND AN INJECTION DEVICE 审中-公开
标题翻译：一种用于预充式注射器和注射装置的安全装置
公开(公告)号：WO2012093072A1
公开(公告)日：2012-07-12
申请号：PCT/EP2011/074277
申请日：2011-12-30
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , SLEMMEN, John , EKMAN, Matthew
发明人： ROBERTS, Gareth , SLEMMEN, John , EKMAN, Matthew
IPC分类号： A61M5/20 , A61M5/32
CPC分类号： A61M5/3202 , A61M5/20 , A61M5/3213 , A61M5/3245 , A61M5/326 , A61M5/3287 , A61M2005/2073 , A61M2005/3223 , A61M2005/3247 , A61M2005/3267 , A61M2205/583 , A61M2205/59
摘要： According to the invention, a safety device (1) for a pre-filled syringe (2) with an injection needle (2.1) comprises - a support body (1.2) adapted to mount the pre-filled syringe (2), - a needle shield (1.1) slidably arranged with respect to the support body (1.2), - a retention and locking means (M) for retaining and locking the needle shield (1.1) with respect to the support body (1.2) in a first and a second advanced position (PA1, PA2) and in a retracted position (PR). The needle shield (1.1) comprises an annular flange (1.1.1) adapted to rest on the skin of the patient receiving an injection. The retention and locking means (M) are arranged at a distal end of the safety device (1).
摘要翻译：根据本发明，用于具有注射针（2.1）的预填充注射器（2）的安全装置（1）包括 - 适于安装预填充注射器（2）的支撑体（1.2）， - 针相对于所述支撑体（1.2）可滑动地布置的护罩（1.1）; - 保持和锁定装置（M），用于在第一和第二部分中相对于所述支撑体（1.2）保持和锁定所述针护罩前进位置（PA1，PA2）和缩回位置（PR）。针护罩（1.1）包括适于搁置在接受注射的患者的皮肤上的环形凸缘（1.1.1）。保持和锁定装置（M）布置在安全装置（1）的远端。

9. 发明申请

WO2012000838A3 SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND INJECTION DEVICE 审中-公开
公开(公告)号：WO2012000838A3
公开(公告)日：2012-01-05
申请号：PCT/EP2011/060322
申请日：2011-06-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
发明人： ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
IPC分类号： A61M5/20 , A61M5/32
摘要： A safety device(1) for a pre-filled syringe(2) comprises a hollow support body (1.2) to retain the pre-filled syringe (2), a retaining collar (1.5) and a rotating collar (1.4) arranged within the support body (1.2). The retaining collar (1.5) is releasably mounted to the support body (1.2). The rotating collar(1.4) is slidable along an axial length of the support body(1.2) and rotatable around a central axis (A) of the safety device (1). The retaining collar (1.5) is movable with respect to the support body (1.2) in a proximal direction when the retaining collar (1.5) is released from being mounted to the support body (1.2) by the rotating collar (1.4).

10. 发明申请

WO2012000836A1 SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND INJECTION DEVICE 审中-公开
标题翻译：一种预充式注射器和注射装置的安全装置
公开(公告)号：WO2012000836A1
公开(公告)日：2012-01-05
申请号：PCT/EP2011/060320
申请日：2011-06-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , WARD, Chris , EKMAN, Matthew
发明人： ROBERTS, Gareth , WARD, Chris , EKMAN, Matthew
IPC分类号： A61M5/50 , A61M5/32
CPC分类号： A61M5/3245 , A61M5/3202 , A61M5/3204 , A61M5/326 , A61M5/3271 , A61M5/3272 , A61M5/3287 , A61M2005/3268
摘要： According to the invention a safety device (1) for a pre-filled syringe (2) comprises a substantially cylindrical and hollow support body (1.2) and a hollow needle shield (1.1) slideably arranged relative to the support body (1.2). The support body (1.2) comprises at least one resilient arm (1.2.3) and the hollow needle shield (1.1) or a needle shield assembly comprises at least one curved actuation ramp (1.1.2). The curved actuation ramp (1.1.2) protrudes in a lateral direction (L) perpendicular to a central axis (A) of the safety device (1). The curved actuation ramp (1.1.2) comprises a first lateral dimension (L1) at a proximal end of the needle shield (1.1) and a second lateral dimension (L2) exceeding the first lateral dimension (L1) at a distal end of the needle shield (1.1). The resilient arm (1.2.3) engages the curved actuation ramp (1.1.2) when the needle shield (1.1) is slid relative to the support body (1.2).
摘要翻译：根据本发明，用于预填充注射器（2）的安全装置（1）包括基本上圆柱形的中空支撑体（1.2）和相对于支撑体（1.2）可滑动地布置的中空针护罩（1.1）。支撑体（1.2）包括至少一个弹性臂（1.2.3）和中空针护罩（1.1）或针护罩组件，其包括至少一个弯曲致动斜面（1.1.2）。弯曲的致动斜面（1.1.2）沿垂直于安全装置（1）的中心轴线（A）的横向方向（L）突出。弯曲的致动斜面（1.1.2）包括在针护罩（1.1）的近端处的第一横向尺寸（L1）和超过第一横向尺寸（L2）的第二横向尺寸（L2）针罩（1.1）。当针护罩（1.1）相对于支撑体（1.2）滑动时，弹性臂（1.2.3）接合弯曲的致动斜面（1.1.2）。

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