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1. 发明申请

WO2012000833A1 SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND INJECTION DEVICE 审中-公开
标题翻译：一种预充式注射器和注射装置的安全装置
公开(公告)号：WO2012000833A1
公开(公告)日：2012-01-05
申请号：PCT/EP2011/060317
申请日：2011-06-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
发明人： ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
IPC分类号： A61M5/32
CPC分类号： A61M5/322 , A61M5/3213 , A61M5/326 , A61M5/3272 , A61M2005/3267 , A61M2205/59
摘要： According to the invention, a safety device (1) for a pre-filled syringe (2) comprises a hollow support body (1.2) having a releasable mounting means (1.2.6) adapted to mount a pre-filled syringe (2) within the support body (1.2), a hollow outer body (1.3) sildably arranged with respect to the support body (1.2) and adapted to receive the support body (1.2) and a release collar (1.4) non-rotatably arranged within the support body (1.2). The release collar (1.4) is movable relative to the support body (1.2) and adapted to release the mounting means (1.2.6). A guide track (1.2.4) is formed into at least one substantially planar side wall (1.2.1 ) of the support body (1.2). The release collar (1.4) comprises at least one flexible arm (1.4.5) with a guide pin (1.4.6) that extends from the flexible arm (1.4.5) and protrudes through the guide track (1.2.4). The guide pin (1.4.6) is movable within and along the guide track (1.2.4) in a plane defined by the substantially planar side wall (1.2.1). A guide rail (1.3.5) is formed into at least one substantially planar inner surface of the outer body (1.3). The guide rail (1.3.5) is adapted to abut against the guide pin (1.4.6) to guide the movement of the guide pin (1.4.6) along the guide track (1.2.4) when the outer body (1.3) is slid relative to the support body (1.2).
摘要翻译：根据本发明，用于预填充注射器（2）的安全装置（1）包括具有适于将预填充的注射器（2）安装在其中的可释放安装装置（1.2.6）的中空支撑体（1.2）所述支撑体（1.2），相对于所述支撑体（1.2）相对于所述支撑体（1.2）发光并且适于接纳所述支撑体（1.2）的空心外体（1.3）和不可旋转地布置在所述支撑体内的释放套环（1.4）（1.2）。释放套环（1.4）可相对于支撑体（1.2）移动并且适于释放安装装置（1.2.6）。引导轨道（1.2.4）形成为支撑体（1.2）的至少一个基本平坦的侧壁（1.2.1）。释放套环（1.4）包括至少一个具有从柔性臂（1.4.5）延伸并通过导轨（1.2.4）突出的引导销（1.4.6）的柔性臂（1.4.5）。引导销（1.4.6）可在导轨（1.2.4）内和沿着基本平坦的侧壁（1.2.1）所限定的平面内移动。导轨（1.3.5）形成为外体（1.3）的至少一个基本平坦的内表面。导轨（1.3.5）适于抵靠引导销（1.4.6），以在外部主体（1.3）上引导引导销（1.4.6）沿导轨（1.2.4）的移动，相对于支撑体（1.2）滑动。

2. 发明申请

WO2012000834A1 SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND INJECTION DEVICE 审中-公开
标题翻译：一种预填充注射器和注射装置的安全装置
公开(公告)号：WO2012000834A1
公开(公告)日：2012-01-05
申请号：PCT/EP2011/060318
申请日：2011-06-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
发明人： ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
IPC分类号： A61M5/32
CPC分类号： A61M5/3271 , A61M5/28 , A61M5/3213 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M2005/3267
摘要： A safety device (1) for a pre-filled syringe (2) comprises a hollow support body (1.2) to retain the pre-filled syringe (2) therein,a hollow needle shield (1.1) that is slidable relative to the support body (1.2)and guiding means for guiding the movement of the needle shield (1.1.) relative to the support body (1.2).The guiding means comprise a deflectable flexible arm (1.1.4), a guide pin (1.1.3) and a guide track (1.2.2). The deflectable flexible arm extends essentially parallel to a central axis (A) of the safety device (1). The guide pin (1.1.3) extends radial from the flexible arm (1.1.4). The guide track (1.2.2) guides the guide pin (1.1.3) within and along the guide track (1.2.2) when the needle shield (1.1) is slid relative to the support body (1.2).
摘要翻译：用于预填充注射器（2）的安全装置（1）包括用于将预填充注射器（2）保持在其中的中空支撑体（1.2），可相对于支撑体滑动的中空针护罩（1.1）（1.2）和用于引导针护罩（1.1）相对于支撑体（1.2）的运动的引导装置。引导装置包括可偏转的柔性臂（1.1.4），引导销（1.1.3）和导轨（1.2.2）。可偏转的柔性臂基本上平行于安全装置（1）的中心轴线（A）延伸。导向销（1.1.3）从柔性臂（1.1.4）径向延伸。当针护罩（1.1）相对于支撑体（1.2）滑动时，导轨（1.2.2）将引导销（1.1.3）引导到引导轨道（1.2.2）内和沿导轨（1.2.2）。

3. 发明申请

WO2012093069A1 ADAPTOR MEANS FOR USE IN COMBINATION WITH A PRE-FILLED SYRINGE AND A SAFETY DEVICE, SAFETY DEVICE AND INJECTION DEVICE 审中-公开
标题翻译：适用于与预充填的注射器和安全装置，安全装置和注射装置组合使用的装置
公开(公告)号：WO2012093069A1
公开(公告)日：2012-07-12
申请号：PCT/EP2011/074274
申请日：2011-12-30
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
发明人： ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
IPC分类号： A61M5/32 , A61M5/28
CPC分类号： A61M5/3243 , A61M5/28 , A61M5/326 , A61M5/3271 , A61M2005/3247
摘要： According to the invention, an adaptor means (1) for use in combination with a pre-filled syringe (2) and a safety device (3) for the pre-filled syringe (2) is adapted to affix the pre-filled syringe (2) thereto, whereby the adaptor means (1) engages a barrel (2.1) of the pre-filled syringe (2). The adaptor means (1) comprises at least one locking projection (1.1.1) that is adapted to lock the adaptor means (1) to the safety device (3).
摘要翻译：根据本发明，用于与预填充注射器（2）和预填充注射器（2）的安全装置（3）组合使用的适配器装置（1）适于将预先填充的注射器 2），由此适配器装置（1）接合预填充注射器（2）的筒体（2.1）。适配器装置（1）包括适于将适配器装置（1）锁定到安全装置（3）的至少一个锁定突起（1.1.1）。

4. 发明申请

WO2012093075A1 SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND INJECTION DEVICE 审中-公开
标题翻译：一种预充式注射器和注射装置的安全装置
公开(公告)号：WO2012093075A1
公开(公告)日：2012-07-12
申请号：PCT/EP2011/074280
申请日：2011-12-30
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
发明人： ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
IPC分类号： A61M5/20 , A61M5/32
CPC分类号： A61M5/3245 , A61M5/3204 , A61M5/3257 , A61M5/326 , A61M5/3287 , A61M2005/3267
摘要： According to the invention, a safety device (1) for a pre-filled syringe (2) comprises a hollow support body 1.2) for retaining the pre-filled syringe (2), a hollow needle shield (1.1) that is movable relative to the support body (1.2) from a first position(I) to a second position (II), releasable mounting means(M) to mount the pre-filled syringe (2) within the support body (1.2) and a spring means (1.4) arranged within the support body(1.2) in a non-energized or only slightly energized state. The movement of the needle shield (1.1) from the first position(I) to the second position(II) fully energizes the spring means (1.4).
摘要翻译：根据本发明，用于预填充注射器（2）的安全装置（1）包括用于保持预填充注射器（2）的中空支撑体1.2），中空针护罩（1.1），其可相对于支撑体（1.2）从第一位置（I）到第二位置（II），可释放的安装装置（M）将预填充的注射器（2）安装在支撑体（1.2）内以及弹簧装置（1.4））布置在支撑体（1.2）内，处于非通电状态或仅微动作状态。针护罩（1.1）从第一位置（I）到第二位置（II）的运动使弹簧装置（1.4）完全通电。

5. 发明申请

WO2012000839A3 NEEDLE SHIELD FOR A SAFETY DEVICE, SAFETY DEVICE AND INJECTION DEVICE 审中-公开
公开(公告)号：WO2012000839A3
公开(公告)日：2012-01-05
申请号：PCT/EP2011/060324
申请日：2011-06-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
发明人： ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
IPC分类号： A61M5/32
摘要： A needle shield (1.1) comprising at least two different plastic materials of different flexibility and a central aperture (1.1.3) of variable diameter (D1, D2). The central aperture (1.1.3) comprises a first diameter (D1) for retaining a needle cap (2.2) therein. The diameter of the central aperture (1.1.3) changes upon removal of the needle cap (2.2) from the first diameter (D1) to a second diameter (D2) by virtue of a memory effect of the material of the needle shield (1.1). The needle shield (1.1) is made by an injection moulding process.

6. 发明申请

WO2012000838A3 SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND INJECTION DEVICE 审中-公开
公开(公告)号：WO2012000838A3
公开(公告)日：2012-01-05
申请号：PCT/EP2011/060322
申请日：2011-06-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
发明人： ROBERTS, Gareth , OWEN, Sioned , EKMAN, Matthew
IPC分类号： A61M5/20 , A61M5/32
摘要： A safety device(1) for a pre-filled syringe(2) comprises a hollow support body (1.2) to retain the pre-filled syringe (2), a retaining collar (1.5) and a rotating collar (1.4) arranged within the support body (1.2). The retaining collar (1.5) is releasably mounted to the support body (1.2). The rotating collar(1.4) is slidable along an axial length of the support body(1.2) and rotatable around a central axis (A) of the safety device (1). The retaining collar (1.5) is movable with respect to the support body (1.2) in a proximal direction when the retaining collar (1.5) is released from being mounted to the support body (1.2) by the rotating collar (1.4).

7. 发明申请

WO2012093070A1 A SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND AN INJECTION DEVICE 审中-公开
标题翻译：一种用于预充填的注射器和注射装置的安全装置
公开(公告)号：WO2012093070A1
公开(公告)日：2012-07-12
申请号：PCT/EP2011/074275
申请日：2011-12-30
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , EKMAN, Matthew
发明人： ROBERTS, Gareth , EKMAN, Matthew
IPC分类号： A61M5/20 , A61M5/32
CPC分类号： A61M5/3234 , A61M5/3202 , A61M5/3243 , A61M5/3257 , A61M5/326 , A61M2005/3241 , A61M2005/3267
摘要： A safety device(1) for a pre-filled syringe (2) is proposed that comprises -a hollow support body (1.2) with a helical groove (1.2.2) formed into an inner surface thereof, -a mounting collar (1.4) for mounting the pre-filled syringe (2) to the support body (1.2), -a spinning collar (1.5) with a helical tongue (1.5.2) formed to an outer surface thereof and -a torsion spring(1.6). The helical groove (1.2.2) accommodates the helical tongue (1.5.2). Upon release, the torsion spring (1.6) is capable of exerting a torque upon the spinning collar (1.5) which causes the spinning collar(1.5) to rotate within the support body(1.2). The engagement of the helical groove (1.2.2) and the helical tongue (1.5.2) redirects the rotational movement of the spinning collar (1.5) to a translatory movement that moves the mounting collar (1.4) in a proximal direction.
摘要翻译：提出了一种用于预填充注射器（2）的安全装置（1），其包括：具有形成在其内表面中的螺旋槽（1.2.2）的中空支撑体（1.2）， - 安装套环（1.4）用于将预填充的注射器（2）安装到支撑体（1.2）上， - 具有形成在其外表面上的螺旋舌（1.5.2）的旋转轴环（1.5）和 - 扭力弹簧（1.6）。螺旋槽（1.2.2）容纳螺旋舌（1.5.2）。释放后，扭转弹簧（1.6）能够在旋转轴环（1.5）上施加扭矩，这使得旋转轴环（1.5）在支撑体（1.2）内旋转。螺旋槽（1.2.2）和螺旋舌（1.5.2）的接合将旋转轴环（1.5）的旋转运动重定向到使得安装套环（1.4）沿近端方向移动的平移运动。

8. 发明申请

WO2012093073A1 SAFETY DEVICE AND INJECTION DEVICE 审中-公开
标题翻译：安全装置和注射装置
公开(公告)号：WO2012093073A1
公开(公告)日：2012-07-12
申请号：PCT/EP2011/074278
申请日：2011-12-30
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , SLEMMEN, John , EKMAN, Matthew
发明人： ROBERTS, Gareth , SLEMMEN, John , EKMAN, Matthew
IPC分类号： A61M5/32
CPC分类号： A61M5/3221 , A61M5/28 , A61M5/3204 , A61M5/326 , A61M5/3287 , A61M2005/3247
摘要： According to the invention, a safety device (1) for a pre-filled syringe (2) comprises a needle shield (1.1) adapted to cover an injection needle (2.1) of the pre-filled syringe (2) before and after an injection, a support body (1.2) with at least one pivoting arm (1.2.2) adapted to engage a barrel collar (2.2.1) of the pre-filled syringe (2) and an outer body (1.3) with a first inner sleeve (1.3.5) comprising a bevelled section (1.3.7). The needle shield (1.1), the support body (1.2) and the outer body(1.3) are telescopically arranged. The needle shield (1.1), the support body (1.2) and the outer body (1.3) may telescope with respect to each other to cover and to expose the injection needle (2.1) of the pre-filled syringe (2).The bevelled section (1.3.7) is arranged to abut against the pivoting arm (1.2.2) connected to the support body (1.2) by a living hinge (1.2.3) to deflect the pivoting arm (1.2.2) radially inwards, so that the pivoting arm may engage the barrel collar after a dose of a medicament contained in the pre-filled syringe has been disposed beneath the skin of a patient receiving the injection.
摘要翻译：根据本发明，用于预填充注射器（2）的安全装置（1）包括适于在注射之前和之后覆盖预填充注射器（2）的注射针（2.1）的针护罩（1.1），具有至少一个枢转臂（1.2.2）的支撑体（1.2），其适于接合预填充的注射器（2）的筒套环（2.2.1）和外部主体（1.3），第一内套筒（1.3.5）包括斜切部分（1.3.7）。针罩（1.1），支撑体（1.2）和外体（1.3）可伸缩地布置。针罩（1.1），支撑体（1.2）和外体（1.3）可以相对于彼此望远镜以覆盖并暴露预填充注射器（2）的注射针（2.1）。斜面（1.3.7）布置成通过活动铰链（1.2.3）抵靠连接到支撑体（1.2）的枢转臂（1.2.2），以使枢转臂（1.2.2）径向向内偏转，因此在预先填充的注射器中包含的药物的剂量已经被布置在接受注射的患者的皮肤下方之前，枢转臂可以与筒套接合。

9. 发明申请

WO2012093071A1 A SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND AN INJECTION DEVICE 审中-公开
标题翻译：一种用于预充式注射器和注射装置的安全装置
公开(公告)号：WO2012093071A1
公开(公告)日：2012-07-12
申请号：PCT/EP2011/074276
申请日：2011-12-30
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , EKMAN, Matthew
发明人： ROBERTS, Gareth , EKMAN, Matthew
IPC分类号： A61M5/50 , A61M5/32 , A61M5/28
CPC分类号： A61M5/326 , A61M5/28 , A61M2005/3261 , A61M2005/3263 , A61M2005/3267
摘要： According to the invention, a safety device(1) for a pre-filled syringe(2) comprises - a support body(1.3) adapted to mount the pre-filled syringe(2), - a first needle shield(1.1) slidably arranged with respect to the support body(1.3) and - a second needle shield(1.2) slidably arranged with respect to the support body(1.4) and releasably retained in a retracted position(PR). A proximal movement of the first needle shield(1.1) with respect to the support body(1.3) releases the retention of the second needle shield(1.2) in the retracted position(PR), so that the second needle shield(1.2) is allowed to slide in the distal direction towards an advanced position(PA).
摘要翻译：根据本发明，用于预填充注射器（2）的安全装置（1）包括 - 适于安装预填充注射器（2）的支撑体（1.3）， - 可滑动地布置的第一针护罩相对于支撑体（1.3）和相对于支撑体（1.4）可滑动地布置并且可释放地保持在缩回位置（PR）中的第二针护罩（1.2）。第一针护罩（1.1）相对于支撑体（1.3）的近端移动释放第二针护罩（1.2）在缩回位置（PR）中的保持，使得允许第二针护罩（1.2）沿远端方向向前进位置（PA）滑动。

10. 发明申请

WO2012000835A1 SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND INJECTION DEVICE 审中-公开
标题翻译：一种预充式注射器和注射装置的安全装置
公开(公告)号：WO2012000835A1
公开(公告)日：2012-01-05
申请号：PCT/EP2011/060319
申请日：2011-06-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , ROBERTS, Gareth , WARD, Chris , EKMAN, Matthew
发明人： ROBERTS, Gareth , WARD, Chris , EKMAN, Matthew
IPC分类号： A61M5/32 , A61M5/50 , A61M5/28
CPC分类号： A61M5/3204 , A61M5/28 , A61M5/326 , A61M5/3272 , A61M2005/3267
摘要： According to the invention, a safety device (1) for a pre-filled syringe (2) comprises a hollow support body (1.2) for mounting the pre-filled syringe (2) therein, a hollow needle shield (1.1) that is slidable relative to the support body (1.2) and guiding means for guiding the movement of the needle shield (1.1) relative to the support body (1.2). The guiding means comprise a flexible arm (1.1.4) with a guide pin (1.1.3), a guide track (1.2.5) and a separating wall (1.2.6). The guide pin (1.1.3) extends from the flexible arm (1.14) in a radial direction, and protrudes into the guide track (1.2.5). The separating wall (1.2.6) extends into the guide track (1.2.5) in a direction parallel to a central axis (A) of the safety device (1). When the needle shield (1.1) is slid relative to the support body (1.2) the guide pin (1.1.3) moves along the guide track (1.2.5) to deflect the flexible arm (1.1.4) in a lateral direction (L) perpendicular to the central axis (A) and the movement of the guide pin (1.1.3) along the guide track (1.2.5) is guided by the interplay of the flexible arm (1.1.4) and the separating wall (1.2.6).
摘要翻译：根据本发明，用于预填充注射器（2）的安全装置（1）包括用于将预填充注射器（2）安装在其中的中空支撑体（1.2），可滑动的中空针护罩（1.1）相对于支撑体（1.2）和用于引导针护罩（1.1）相对于支撑体（1.2）的移动的引导装置。引导装置包括具有引导销（1.1.3），导轨（1.2.5）和分隔壁（1.2.6）的柔性臂（1.1.4）。引导销（1.1.3）从柔性臂（1.14）沿径向方向延伸，并突出到导轨（1.2.5）中。分离壁（1.2.6）在平行于安全装置（1）的中心轴线（A）的方向上延伸到导轨（1.2.5）中。当针护罩（1.1）相对于支撑体（1.2）滑动时，引导销（1.1.3）沿着导轨（1.2.5）移动，以使柔性臂（1.1.4）沿横向（垂直于中心轴线（A）的L（L）和引导销（1.1.3）沿着导轨（1.2.5）的移动由柔性臂（1.1.4）和分隔壁 1.2.6）。

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