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1. 发明授权

US10052195B2 Adaptive intraocular lens 有权
公开(公告)号：US10052195B2
公开(公告)日：2018-08-21
申请号：US13885366
申请日：2011-11-14
申请人： Ronald David Blum , Rudy Mazzocchi
发明人： Ronald David Blum , Rudy Mazzocchi
IPC分类号： A61F2/16
CPC分类号： A61F2/1624 , A61F2/1613 , A61F2/1627 , A61F2/1635 , A61F2/1648 , A61F2210/008 , A61F2210/009
摘要： An implantable ophthalmic device with flexible, fluid-filled membranes provide dynamically variable optical power to restore lost accommodation in individuals suffering from presbyopia or aphakia without moving parts or reducing the amount of transmitted light. Actuating the device causes the fluid-filled membrane to change curvature, which produces a corresponding change in optical power. For instance, squeezing the edge of the membrane causes the center of the membrane to bulge by an amount proportional to the squeezing force. Alternatively, heating or applying a voltage to the membrane may cause the liquid in the membrane to undergo a phase transition accompanied by a corresponding change in volume that causes the membrane to inflate so as to change the optical power of the device.

2. 发明申请

US20130338767A1 DEVICES AND METHODS FOR DYNAMIC FOCUSING MOVEMENT 审中-公开
标题翻译：用于动态聚焦运动的装置和方法
公开(公告)号：US20130338767A1
公开(公告)日：2013-12-19
申请号：US13976406
申请日：2011-12-28
申请人： Rudy Mazzocchi , Ronald David Blum
发明人： Rudy Mazzocchi , Ronald David Blum
IPC分类号： A61F2/16
CPC分类号： A61F2/1635 , A61F2/1629 , A61F2/1648 , A61F2002/1681 , A61F2210/0014 , A61F2210/0023 , A61F2210/0033 , A61F2210/0038 , A61F2250/0002
摘要： An implantable ophthalmic device with one or more optical elements coupled to one or more shape-memory members provides dynamically variable optical power to restore lost accommodation in individuals suffering from presbyopia or aphakia. Running current from a power supply through the shape-memory members causes the shape-memory members to heat up. Once the current heats the shape-memory members past a forward phase-transition temperature, the shape-memory members change shape, which, in turn, causes the optical element(s) to move, yielding a corresponding change in effective optical power. Cooling the shape-memory members (e.g., by reducing or stopping the flow of current) below a reverse phase-transition temperature causes the shape-memory members to return to their original shape, which, in turn, restoring the optical element(s) to their original positions and returning the effective optical power to its original level.
摘要翻译：具有耦合到一个或多个形状记忆部件的一个或多个光学元件的可植入眼科装置提供动态可变的光学功率，以恢复患有老花眼或无晶状体的个体的失去的适应性。从电源通过形状记忆部件运行电流导致形状记忆部件加热。一旦电流加热形状记忆元件超过正向相变温度，则形状记忆元件改变形状，这又导致光学元件移动，产生有效光功率的相应变化。将形状记忆体（例如，通过减少或停止电流的流动）冷却到反相转变温度以下，导致形状记忆元件返回到其原始形状，这反过来恢复光学元件，到原来的位置，并将有效光功率恢复到原来的水平。

3. 发明申请

US20130245754A1 ADAPTIVE INTRAOCULAR LENS 审中-公开
标题翻译：自适应眼科镜片
公开(公告)号：US20130245754A1
公开(公告)日：2013-09-19
申请号：US13885366
申请日：2011-11-14
申请人： Ronald David Blum , Rudy Mazzocchi
发明人： Ronald David Blum , Rudy Mazzocchi
IPC分类号： A61F2/16
CPC分类号： A61F2/1624 , A61F2/1613 , A61F2/1627 , A61F2/1635 , A61F2/1648 , A61F2210/008 , A61F2210/009
摘要： An implantable ophthalmic device with flexible, fluid-filled membranes provide dynamically variable optical power to restore lost accommodation in individuals suffering from presbyopia or aphakia without moving parts or reducing the amount of transmitted light. Actuating the device causes the fluid-filled membrane to change curvature, which produces a corresponding change in optical power. For instance, squeezing the edge of the membrane causes the center of the membrane to bulge by an amount proportional to the squeezing force. Alternatively, heating or applying a voltage to the membrane may cause the liquid in the membrane to undergo a phase transition accompanied by a corresponding change in volume that causes the membrane to inflate so as to change the optical power of the device.
摘要翻译：具有柔性流体填充膜的可植入眼科装置提供动态可变的光学功率，以恢复患有老花眼或无晶状体的个体的失去的适应性，而无需移动部件或减少透射光量。驱动该装置导致流体填充的膜改变曲率，这产生相应的光功率变化。例如，挤压膜的边缘导致膜的中心膨胀与挤压力成比例的量。或者，加热或向膜施加电压可能导致膜中的液体经历伴随相应的体积变化的相变，导致膜膨胀以改变装置的光功率。

4. 发明授权

US07828815B2 Method and device for filtering body fluid 有权
公开(公告)号：US07828815B2
公开(公告)日：2010-11-09
申请号：US11120830
申请日：2005-05-03
申请人： Rudy Mazzocchi , Timothy Claude , James Segermark
发明人： Rudy Mazzocchi , Timothy Claude , James Segermark
IPC分类号： A61F11/00 , A61M29/00
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12099 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B17/12177 , A61B17/221 , A61B2017/00526 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2230/008 , B21F45/008
摘要： Medical devices for filtering fluids flowing through a lumen and a method of forming medical devices. The devices can be used in vascular channels, urinary tracts, biliary ducts and the like, and filter emboli and other debris generated at a treatment site.

5. 发明授权

US07578829B2 Medical grafting methods and apparatus 失效
公开(公告)号：US07578829B2
公开(公告)日：2009-08-25
申请号：US10680036
申请日：2003-10-06
申请人： David S. Goldsteen , Thomas J. Bachinski , Rudy Mazzocchi , Daniel J. Sullivan
发明人： David S. Goldsteen , Thomas J. Bachinski , Rudy Mazzocchi , Daniel J. Sullivan
IPC分类号： A61B17/08
CPC分类号： A61B1/0058 , A61B17/0057 , A61B17/11 , A61B17/1114 , A61B17/221 , A61B17/32056 , A61B2017/003 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139 , A61B2017/2212 , A61B2017/2939 , A61B2090/306 , A61B2090/3614 , A61F2/06 , A61F2/064 , A61F2/07 , A61F2/90 , A61F2/95 , A61F2/954 , A61F2/958 , A61F2002/061 , A61F2002/065 , A61F2002/3008 , A61F2002/30092 , A61F2002/826 , A61F2002/8486 , A61F2210/0014 , A61F2240/001 , A61F2250/0098 , A61M25/0041 , A61M25/0108 , A61M25/0133 , A61M25/0147 , A61M25/0152 , A61M25/04 , A61M25/09025 , A61M2025/0293 , A61M2025/1052 , Y10S623/903
摘要： Methods and apparatus for delivering and installing a new length of tubing between two sections of a patient's existing body organ tubing and at least partly outside of that existing structure. For example, the new length of tubing may be for the purpose of providing the patient with a coronary bypass. The new tubing may be an artificial graft, a natural graft (harvested elsewhere from the patient), or both. The new tubing is delivered to and installed at the operative site primarily by working through the patient's existing tubular body organ structure. This avoids the need for any significant surgery on the patient. The artificial grafts may have shapes other than tubular. Certain procedural and apparatus aspects of the invention have uses other than in connection with grafting in general or tubular grafting in particular.

6. 发明申请

US20080071309A1 METHOD AND DEVICE FOR FILTERING BODY FLUID 失效
公开(公告)号：US20080071309A1
公开(公告)日：2008-03-20
申请号：US11939827
申请日：2007-11-14
申请人： Rudy Mazzocchi , Timothy Claude , James Segermark
发明人： Rudy Mazzocchi , Timothy Claude , James Segermark
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12099 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B17/12177 , A61B17/221 , A61B2017/00526 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2230/008 , B21F45/008
摘要： Medical devices for filtering fluids flowing through a lumen and a method of forming medical devices. The devices can be used in vascular channels, urinary tracts, biliary ducts and the like, and filter emboli and other debris generated at a treatment site.

7. 发明申请

US20080065146A1 METHOD AND DEVICE FOR FILTERING BODY FLUID 失效
公开(公告)号：US20080065146A1
公开(公告)日：2008-03-13
申请号：US11939888
申请日：2007-11-14
申请人： Rudy Mazzocchi , Timothy Claude , James Segermark
发明人： Rudy Mazzocchi , Timothy Claude , James Segermark
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12099 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B17/12177 , A61B17/221 , A61B2017/00526 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2230/008 , B21F45/008
摘要： Medical devices for filtering fluids flowing through a lumen and a method of forming medical devices. The devices can be used in vascular channels, urinary tracts, biliary ducts and the like, and filter emboli and other debris generated at a treatment site.

8. 发明申请

US20070255275A1 SHEATH ASSEMBLY FOR AN ACCESS DEVICE AND METHOD THEREFOR 有权
标题翻译：用于访问设备的护套组件及其方法
公开(公告)号：US20070255275A1
公开(公告)日：2007-11-01
申请号：US11768741
申请日：2007-06-26
申请人： James Skakoon , Robert Wharen , Matthew Solar , Kari Parmer , Rudy Mazzocchi , John David , Frank Murdock , David Hatcher , Thomas Miller , Timothy Parmer , Charles Truwit
发明人： James Skakoon , Robert Wharen , Matthew Solar , Kari Parmer , Rudy Mazzocchi , John David , Frank Murdock , David Hatcher , Thomas Miller , Timothy Parmer , Charles Truwit
IPC分类号： A61B18/18
CPC分类号： A61N1/0539 , A61B34/20 , A61B90/11 , A61B2017/0023 , A61B2017/00398 , A61B2017/00911 , A61B2017/3407 , A61B2017/3409 , A61B2017/3411 , A61B2017/347 , A61B2034/2051 , A61B2034/2055 , A61B2090/103 , A61B2090/363 , A61B2090/374 , A61B2090/3762 , A61B2090/3983 , A61N1/0534
摘要： Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems.
摘要翻译：装置和方法提供将电极或其他器械精确地靶向，放置和/或稳定到脑或其他身体器官中，例如治疗严重的震颤或其它神经障碍。使用任何形式的图像引导进行定向，包括实时MRI，CT或无框架手术导航系统。

9. 发明申请

US20070250076A1 DEVICE FOR IMMOBILIZING A PRIMARY INSTRUMENT AND METHOD THEREFOR 有权
公开(公告)号：US20070250076A1
公开(公告)日：2007-10-25
申请号：US11768077
申请日：2007-06-25
申请人： James Skakoon , Robert Wharen , Matthew Solar , Kari Parmer , Rudy Mazzocchi , John David , Frank Murdock , David Hatcher , Thomas Miller , Timothy Parmer , Charles Truwit
发明人： James Skakoon , Robert Wharen , Matthew Solar , Kari Parmer , Rudy Mazzocchi , John David , Frank Murdock , David Hatcher , Thomas Miller , Timothy Parmer , Charles Truwit
IPC分类号： A61B19/00
CPC分类号： A61N1/0539 , A61B34/20 , A61B90/11 , A61B2017/0023 , A61B2017/00398 , A61B2017/00911 , A61B2017/3407 , A61B2017/3409 , A61B2017/3411 , A61B2017/347 , A61B2034/2051 , A61B2034/2055 , A61B2090/103 , A61B2090/363 , A61B2090/374 , A61B2090/3762 , A61B2090/3983 , A61N1/0534
摘要： Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems.

10. 发明授权

US07048752B2 Method and device for filtering body fluid 有权
公开(公告)号：US07048752B2
公开(公告)日：2006-05-23
申请号：US10051648
申请日：2002-01-18
申请人： Rudy Mazzocchi , Timothy Claude , James Segermark
发明人： Rudy Mazzocchi , Timothy Claude , James Segermark
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12099 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B17/12177 , A61B17/221 , A61B2017/00526 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2230/008 , B21F45/008
摘要： Medical devices for filtering fluids flowing through a lumen and a method of forming medical devices. The devices can be used in vascular channels, urinary tracts, biliary ducts and the like, and filter emboli and other debris generated at a treatment site.

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