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    • 2. 发明申请
    • Fungicides
    • US20060240988A1
    • 2006-10-26
    • US10536516
    • 2003-11-10
    • Roger SalmonPatrick CrowleyDavid Bacon
    • Roger SalmonPatrick CrowleyDavid Bacon
    • A01N37/18
    • C07D249/08A01N39/04C07C235/20C07C255/30C07C317/28C07C323/41
    • Fungicidal compounds of the general formula (1): wherein X, Y and Z are independently H, halogen, C1-4 alkyl, halo(C1-4)alkyl, C2-4alkenyl, halo(C2-4)alkenyl, C24 alkynyl, halo(C2-4)alkynyl, C1-4 alkoxy, halo(C1-4)alkoxy, —S(O)n(C1-4)alkyl where n is 0, 1 or 2 and the alkyl group is optionally substituted with fluoro, —OS02(C1-4)alkyl where the alkyl group is optionally substituted with fluoro, cyano, nitro, C1-4 alkoxycarbonyl, —CONR′R″, —COR′, —NR′COR″ or —NR′COOR′″ where R′ and R″ are independently H or C1-4, alkyl and R′″ is C1-4 alkyl, provided that at least one of X and Z is other than H; R1 is C1-4alkyl, C2-4 alkenyl or C2-4 alkynyl in which the alkyl, alkenyl and alkynyl groups are optionally substituted on their terminal carbon atom with one, two or three halogen atoms, with a cyano group, with a C1-4 alkylcarbonyl group, with a C1-4 alkoxycarbonyl group or with a hydroxy group; R2 is H, C1-4 alkyl, C1-4 alkoxymethyl or benzyloxymethyl in which the phenyl ring of the benzyl moiety is optionally substituted with C1-4alkoxy; R3 and R4 are independently H, C1-3 alkyl, C2-3 alkenyl or C2-3 alkynyl provided that both are not H and that when both are other than H their combined total of carbon atoms does not exceed 4, or R3 and R4 join with the carbon atom to which they are attached to form a 3 or 4 membered carbocyclic ring optionally containing one 0, S or N atom and optionally substituted with halo or C1-4alkyl; and R5 is unsubstituted C3-4 alkyl, unsubstituted C3-6 cycloalkyl or C1-4 alkyl or C3-6 cycloalkyl in which the alkyl and cycloalkyl groups are substituted with halo, hydroxy, C1-6 alkoxy, cyano, C1-4 alkylcarbonyloxy, aminocarbonyloxy, mono- or di(C1-4)alkylaminocarbonyloxy, —S(O)″(C1-6)alkyl where n is 0, 1 or 2, triazolyl, tri(C1-4)alkylsilyloxy, optionally substituted phenoxy, optionally substituted thienyloxy, optionally substituted benzyloxy or optionally substituted thienyl-methoxy, in which the optionally substituted phenyl and thienyl rings of phenoxy, thienyloxy, benzyloxy and thienylmethoxy are optionally substituted with one, two or three substituents selected from halo, hydroxy, mercapto, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4alkoxy, C2-4 alkenyloxy, C2-4 alkynyloxy, halo(C1-4)alkyl, halo(C1-4)alkoxy, C1-4 alkylthio; halo(C1-4)alkylthio, hydroxy(C1-4)alkyl, C1-4 alkoxy(C1-4)alkyl, C3-6 cycloalkyl, C3-6 cycloalkyl(C1-4)alkyl, phenoxy, benzyloxy, benzoyloxy, cyano, isocyano, thiocyanato, isothiocyanato, nitro, —NR—R′, —NHCORm, —NHCONRmR″, —CONRmR″, —S02Rm, —OS02Rm, —CORM, —CR′═NR″ or —N═CRmR″, in which R′″ and R″ are independently hydrogen, CI-4 alkyl, halo(C1-4)alkyl, C1-4 alkoxy, halo(C1-4)alkoxy, C1-4alkylthio, C3-6 cycloalkyl, C3-6 cycloalkyl(C1-4)alkyl, phenyl or benzyl, the phenyl and benzyl groups being optionally substituted with halogen, C1-4alkyl or C1-4 alkoxy.
    • 9. 发明申请
    • Fungicides
    • 杀菌剂
    • US20070066605A1
    • 2007-03-22
    • US10540040
    • 2003-12-04
    • Patrick CrowleyMarkus DoblerUrs MuellerJohn Williams
    • Patrick CrowleyMarkus DoblerUrs MuellerJohn Williams
    • C07D487/02A01N43/90
    • C07D239/42A01N43/90C07D471/04
    • Fungicidal compositions having the general formula (1): formula (1) wherein W and Y are both N and X and Z are both CR8 or X and Z are both N and W and Y are both C6, R8 is H, halo, C1-4 alkyl, C1-4alkoxy or halo(C1-4)alkyl; R and R2 are independently H, halo, C1-8alkyl, C1-8alkoxy, C1-8alkylthio, C2-8alkenyl, C2-8 alkynyl, cyano or NR3R4, provided that at least one of R and R2 is NR3R4; R1 is halo, C1-8alkyl, C2-8alkenyl, C2-8alkynyl, C3-8cycloalkyl, C3-8cycloalkyl(C1-6)-alkyl, C1-8alkoxy, C1-8 alkylthio, aryl, aryloxy, arylthio, heteroaryl, heteroaryloxy, heteroarylthio, aryl(C1-4)alkyl, aryl(CI4,)alkoxy, heteroaryl(C1-4)alkyl, heteroaryl(C1-4)alkoxy, aryl(C1-4)alkylthio, heteroaryl(C1-4)alkylthiio, morpholiiio, piperidino or pynrolidino.
    • 具有通式(1):式(1)的杀真菌组合物,其中W和Y都是N,X和Z都是CR 8或X和Z都是N,W和Y都是C R 8是H,卤素,C 1-4烷基,C 1-4烷氧基或卤代 (C 1-4烷基)烷基; R和R 2独立地为H,卤素,C 1-8烷基,C 1-8烷氧基,C 1-8 C 2〜C 8烷基,C 2-8链烯基,C 2-8炔基,氰基或NR 3 R 4, SUP>,条件是R和R 2中的至少一个是NR 3 R 4; R 1是卤素,C 1-8烷基,C 2-8链烯基,C 2-8炔基 C 3-8环烷基,C 3-8环烷基(C 1-6 - ) - 烷基,C 1-8 - C 1-4烷基,芳基,芳氧基,芳硫基,杂芳基,杂芳氧基,杂芳硫基,芳基(C 1-4 - )烷基,芳基(C 1-4, )烷氧基,杂芳基(C 1-4 - )烷基,杂芳基(C 1-4 - )烷氧基,芳基(C 1-4 - )烷硫基 ,杂芳基(C 1-4烷基)硫代,吗啉代,哌啶子基或鸟嘌呤基。